Cooperation of structurally different aryl hydrocarbon receptor agonists and β-catenin in the regulation of CYP1A expression

Toxicology

Volumn 325, Issue , 2014, Pages 31-41

  Vaas, Sebastian ^a   Kreft, Luisa ^a   Schwarz, Michael ^a   Braeuning, Albert ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

Cytochrome P450; Dioxin receptor; Liver zonation; Perivenous hepatocyte; TCDD; Wnt signaling

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; 3 METHYLCHOLANTHRENE; AXIN; AXIN2; BETA CATENIN; BETA NAPHTHOFLAVONE; CYTOCHROME P450 1A1; CYTOCHROME P450 1A2; G PROTEIN COUPLED RECEPTOR; UNCLASSIFIED DRUG; AHR PROTEIN, MOUSE; AROMATIC HYDROCARBON RECEPTOR; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; CTNNB1 PROTEIN, MOUSE; CYTOCHROME P450 1A2 INDUCER; LIGAND; MESSENGER RNA; BUTYLATED HYDROXYANISOLE; CYTOCHROME P450 1A; GLUTATHIONE TRANSFERASE; TAMOXIFEN;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; GENE EXPRESSION; GENE INDUCTION; GENOTYPE; GPR49 PROTEIN; HUMAN; HUMAN CELL; LIVER CELL; MALE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; WNT SIGNALING PATHWAY; ZONATION; AGONISTS; ANIMAL; BIOSYNTHESIS; CHEMICAL STRUCTURE; CHEMISTRY; DEFICIENCY; DOSE RESPONSE; DRUG EFFECTS; ENZYME INDUCTION; ENZYMOLOGY; GENETICS; KNOCKOUT MOUSE; LIVER; METABOLISM; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION; TUMOR CELL LINE; BODY WEIGHT; DRUG PROTEIN BINDING; DRUG STRUCTURE; HEPATOMA CELL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; PROTEIN EXPRESSION; PROTEIN STRUCTURE;

ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BETA CATENIN; CELL LINE, TUMOR; CYTOCHROME P-450 CYP1A1; CYTOCHROME P-450 CYP1A2; CYTOCHROME P-450 CYP1A2 INDUCERS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INDUCTION; HEPATOCYTES; LIGANDS; LIVER; MICE, KNOCKOUT; MOLECULAR STRUCTURE; RECEPTORS, ARYL HYDROCARBON; RNA, MESSENGER; SIGNAL TRANSDUCTION; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84906861848     PISSN: 0300483X     EISSN: 18793185     Source Type: Journal    
DOI: 10.1016/j.tox.2014.08.010     Document Type: Article

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