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Volumn 18, Issue 8, 2014, Pages 1623-1630

Treatment with actovegin improves spatial learning and memory in rats following transient forebrain ischaemia

Author keywords

Actovegin; Ischaemia; Learning; Memory; Neuroprotection; Stroke

Indexed keywords

RATTUS;

EID: 84906818491     PISSN: 15821838     EISSN: 15824934     Source Type: Journal    
DOI: 10.1111/jcmm.12297     Document Type: Article
Times cited : (29)

References (40)
  • 1
    • 0345830736 scopus 로고    scopus 로고
    • Burden of first-ever ischemic stroke in the oldest old: evidence from a population-based study
    • Marini C, Baldassarre M, Russo T, et al. Burden of first-ever ischemic stroke in the oldest old: evidence from a population-based study. Neurology. 2004; 62: 77-81.
    • (2004) Neurology , vol.62 , pp. 77-81
    • Marini, C.1    Baldassarre, M.2    Russo, T.3
  • 2
    • 0031924906 scopus 로고    scopus 로고
    • Economic burden of stroke and the evaluation of new therapies
    • Kaste M, Fogelholm R, Rissanen A. Economic burden of stroke and the evaluation of new therapies. Public Health. 1998; 112: 103-12.
    • (1998) Public Health , vol.112 , pp. 103-112
    • Kaste, M.1    Fogelholm, R.2    Rissanen, A.3
  • 3
    • 0030890075 scopus 로고    scopus 로고
    • Dementia three months after stroke. Baseline frequency and effect of different definitions of dementia in the Helsinki Stroke Aging Memory Study (SAM) cohort
    • Pohjasvaara T, Erkinjuntti T, Vataja R, et al. Dementia three months after stroke. Baseline frequency and effect of different definitions of dementia in the Helsinki Stroke Aging Memory Study (SAM) cohort. Stroke. 1997; 28: 785-92.
    • (1997) Stroke , vol.28 , pp. 785-792
    • Pohjasvaara, T.1    Erkinjuntti, T.2    Vataja, R.3
  • 4
    • 33646676302 scopus 로고    scopus 로고
    • Clinical determinants of dementia and mild cognitive impairment following ischaemic stroke: the Sydney Stroke Study
    • Sachdev PS, Brodaty H, Valenzuela MJ, et al. Clinical determinants of dementia and mild cognitive impairment following ischaemic stroke: the Sydney Stroke Study. Dement Geriatr Cogn Disord. 2006; 21: 275-83.
    • (2006) Dement Geriatr Cogn Disord , vol.21 , pp. 275-283
    • Sachdev, P.S.1    Brodaty, H.2    Valenzuela, M.J.3
  • 5
    • 33845338724 scopus 로고    scopus 로고
    • Projections of global mortality and burden of disease from 2002 to 2030
    • Mathers CD, Loncar D. Projections of global mortality and burden of disease from 2002 to 2030. PLoS Med. 2006; 3: e442.
    • (2006) PLoS Med , vol.3
    • Mathers, C.D.1    Loncar, D.2
  • 6
    • 79960796056 scopus 로고    scopus 로고
    • Investigational therapies for ischemic stroke: neuroprotection and neurorecovery
    • Sahota P, Savitz SI. Investigational therapies for ischemic stroke: neuroprotection and neurorecovery. Neurotherapeutics. 2011; 8: 434-51.
    • (2011) Neurotherapeutics , vol.8 , pp. 434-451
    • Sahota, P.1    Savitz, S.I.2
  • 7
    • 33644818304 scopus 로고    scopus 로고
    • 1,026 experimental treatments in acute stroke
    • O'Collins VE, Macleod MR, Donnan GA, et al. 1, 026 experimental treatments in acute stroke. Ann Neurol. 2006; 59: 467-77.
    • (2006) Ann Neurol , vol.59 , pp. 467-477
    • O'Collins, V.E.1    Macleod, M.R.2    Donnan, G.A.3
  • 8
    • 48849089052 scopus 로고    scopus 로고
    • Neuroprotection for ischemic stroke: past, present and future
    • Ginsberg MD. Neuroprotection for ischemic stroke: past, present and future. Neuropharmacology. 2008; 55: 363-89.
    • (2008) Neuropharmacology , vol.55 , pp. 363-389
    • Ginsberg, M.D.1
  • 9
    • 80052690917 scopus 로고    scopus 로고
    • The ischemic penumbra: correlates in imaging and implications for treatment of ischemic stroke. The Johann Jacob Wepfer award 2011
    • Heiss WD. The ischemic penumbra: correlates in imaging and implications for treatment of ischemic stroke. The Johann Jacob Wepfer award 2011. Cerebrovasc Dis. 2011; 32: 307-20.
    • (2011) Cerebrovasc Dis , vol.32 , pp. 307-320
    • Heiss, W.D.1
  • 10
    • 71049180369 scopus 로고    scopus 로고
    • Inflammatory mechanisms in ischemic stroke: therapeutic approaches
    • Lakhan SE, Kirchgessner A, Hofer M. Inflammatory mechanisms in ischemic stroke: therapeutic approaches. J Transl Med. 2009; 7: 97.
    • (2009) J Transl Med , vol.7 , pp. 97
    • Lakhan, S.E.1    Kirchgessner, A.2    Hofer, M.3
  • 11
    • 0030976784 scopus 로고    scopus 로고
    • Reperfusion damage following focal ischemia: pathophysiology and therapeutic windows
    • Kuroda S, Siesjo BK. Reperfusion damage following focal ischemia: pathophysiology and therapeutic windows. Clin Neurosci. 1997; 4: 199-212.
    • (1997) Clin Neurosci , vol.4 , pp. 199-212
    • Kuroda, S.1    Siesjo, B.K.2
  • 12
    • 35649015344 scopus 로고    scopus 로고
    • NADPH oxidase plays a central role in blood-brain barrier damage in experimental stroke
    • Kahles T, Luedike P, Endres M, et al. NADPH oxidase plays a central role in blood-brain barrier damage in experimental stroke. Stroke. 2007; 38: 3000-6.
    • (2007) Stroke , vol.38 , pp. 3000-3006
    • Kahles, T.1    Luedike, P.2    Endres, M.3
  • 13
    • 33846993419 scopus 로고    scopus 로고
    • Peroxynitrite diminishes myogenic tone in cerebral arteries: role of nitrotyrosine and F-actin
    • Maneen MJ, Cipolla MJ. Peroxynitrite diminishes myogenic tone in cerebral arteries: role of nitrotyrosine and F-actin. Am J Physiol Heart Circ Physiol. 2007; 292: H1042-50.
    • (2007) Am J Physiol Heart Circ Physiol , vol.292
    • Maneen, M.J.1    Cipolla, M.J.2
  • 14
    • 84867582424 scopus 로고    scopus 로고
    • Neuroprotection in vascular dementia: a future path
    • Skoog I, Korczyn AD, Guekht A. Neuroprotection in vascular dementia: a future path. J Neurol Sci. 2012; 322: 232-6.
    • (2012) J Neurol Sci , vol.322 , pp. 232-236
    • Skoog, I.1    Korczyn, A.D.2    Guekht, A.3
  • 15
    • 68149106189 scopus 로고    scopus 로고
    • Treatment of symptomatic polyneuropathy with actovegin in type 2 diabetic patients
    • Ziegler D, Movsesyan L, Mankovsky B, et al. Treatment of symptomatic polyneuropathy with actovegin in type 2 diabetic patients. Diabetes Care. 2009; 32: 1479-84.
    • (2009) Diabetes Care , vol.32 , pp. 1479-1484
    • Ziegler, D.1    Movsesyan, L.2    Mankovsky, B.3
  • 16
    • 33644669423 scopus 로고
    • Actovegin infusion treatment in patients with primarily degenerative dementia of the Alzheimer type and multi-infarct dementia
    • Herrmann WM, Bohn-Olszewsky WJ, Kuntz G. Actovegin infusion treatment in patients with primarily degenerative dementia of the Alzheimer type and multi-infarct dementia. Zeitschrift für Geriatrie. 1992; 5: 46-55.
    • (1992) Zeitschrift für Geriatrie , vol.5 , pp. 46-55
    • Herrmann, W.M.1    Bohn-Olszewsky, W.J.2    Kuntz, G.3
  • 17
    • 0029148184 scopus 로고
    • Confirmed clinical efficacy of Actovegin in elderly patients with organic brain syndrome
    • Kanowski S, Kinzler E, Lehmann E, et al. Confirmed clinical efficacy of Actovegin in elderly patients with organic brain syndrome. Pharmacopsychiatry. 1995; 28: 125-33.
    • (1995) Pharmacopsychiatry , vol.28 , pp. 125-133
    • Kanowski, S.1    Kinzler, E.2    Lehmann, E.3
  • 18
    • 84858151034 scopus 로고    scopus 로고
    • Treatment with Actovegin(R) improves sensory nerve function and pathology in streptozotocin-diabetic rats via mechanisms involving inhibition of PARP activation
    • Dieckmann A, Kriebel M, Andriambeloson E, et al. Treatment with Actovegin(R) improves sensory nerve function and pathology in streptozotocin-diabetic rats via mechanisms involving inhibition of PARP activation. Exp Clin Endocrinol Diabetes. 2012; 120: 132-8.
    • (2012) Exp Clin Endocrinol Diabetes , vol.120 , pp. 132-138
    • Dieckmann, A.1    Kriebel, M.2    Andriambeloson, E.3
  • 19
    • 84855879666 scopus 로고    scopus 로고
    • Neuroprotective and anti-oxidative effects of the hemodialysate actovegin on primary rat neurons in vitro
    • Elmlinger MW, Kriebel M, Ziegler D. Neuroprotective and anti-oxidative effects of the hemodialysate actovegin on primary rat neurons in vitro. Neuromolecular Med. 2011; 13: 266-74.
    • (2011) Neuromolecular Med , vol.13 , pp. 266-274
    • Elmlinger, M.W.1    Kriebel, M.2    Ziegler, D.3
  • 20
    • 84867577337 scopus 로고    scopus 로고
    • Pleiotropic neuroprotective and metabolic effects of Actovegin's mode of action
    • Machicao F, Muresanu DF, Hundsberger H, et al. Pleiotropic neuroprotective and metabolic effects of Actovegin's mode of action. J Neurol Sci. 2012; 322: 222-7.
    • (2012) J Neurol Sci , vol.322 , pp. 222-227
    • Machicao, F.1    Muresanu, D.F.2    Hundsberger, H.3
  • 21
    • 79953307499 scopus 로고    scopus 로고
    • Actovegin(R): a biological drug for more than 5 decades
    • Buchmayer F, Pleiner J, Elmlinger MW, et al. Actovegin(R): a biological drug for more than 5 decades. Wien Med Wochenschr. 2011; 161: 80-8.
    • (2011) Wien Med Wochenschr , vol.161 , pp. 80-88
    • Buchmayer, F.1    Pleiner, J.2    Elmlinger, M.W.3
  • 22
    • 84882608622 scopus 로고    scopus 로고
    • GluR6-FasL-Trx2 mediates denitrosylation and activation of procaspase-3 in cerebral ischemia/reperfusion in rats
    • Sun N, Hao JR, Li XY, et al. GluR6-FasL-Trx2 mediates denitrosylation and activation of procaspase-3 in cerebral ischemia/reperfusion in rats. Cell Death Dis. 2013; 4: e771.
    • (2013) Cell Death Dis , vol.4
    • Sun, N.1    Hao, J.R.2    Li, X.Y.3
  • 23
    • 84878564227 scopus 로고    scopus 로고
    • Partial role of multiple pathways in infarct size limiting effect of quercetin and rutin against cerebral ischemia-reperfusion injury in rats
    • Annapurna A, Ansari MA, Manjunath PM. Partial role of multiple pathways in infarct size limiting effect of quercetin and rutin against cerebral ischemia-reperfusion injury in rats. Eur Rev Med Pharmacol Sci. 2013; 17: 491-500.
    • (2013) Eur Rev Med Pharmacol Sci , vol.17 , pp. 491-500
    • Annapurna, A.1    Ansari, M.A.2    Manjunath, P.M.3
  • 24
    • 0023724443 scopus 로고
    • The four-vessel occlusion rat model: method for complete occlusion of vertebral arteries and control of collateral circulation
    • Pulsinelli WA, Buchan AM. The four-vessel occlusion rat model: method for complete occlusion of vertebral arteries and control of collateral circulation. Stroke. 1988; 19: 913-4.
    • (1988) Stroke , vol.19 , pp. 913-914
    • Pulsinelli, W.A.1    Buchan, A.M.2
  • 25
    • 0018347695 scopus 로고
    • A new model of bilateral hemispheric ischemia in the unanesthetized rat
    • Pulsinelli WA, Brierley JB. A new model of bilateral hemispheric ischemia in the unanesthetized rat. Stroke. 1979; 10: 267-72.
    • (1979) Stroke , vol.10 , pp. 267-272
    • Pulsinelli, W.A.1    Brierley, J.B.2
  • 26
    • 84871433905 scopus 로고    scopus 로고
    • Piperphentonamine (PPTA) attenuated cerebral ischemia-induced memory deficits via neuroprotection associated with anti-apoptotic activity
    • Bin J, Wang Q, Zhuo YY, et al. Piperphentonamine (PPTA) attenuated cerebral ischemia-induced memory deficits via neuroprotection associated with anti-apoptotic activity. Metab Brain Dis. 2012; 27: 495-505.
    • (2012) Metab Brain Dis , vol.27 , pp. 495-505
    • Bin, J.1    Wang, Q.2    Zhuo, Y.Y.3
  • 27
    • 0022483830 scopus 로고
    • Forebrain ischemia in the rat. Relation between duration of ischemia, use of adjunctive ganglionic blockade and long-term recovery
    • Grogaard B, Gerdin B, Arfors KE. Forebrain ischemia in the rat. Relation between duration of ischemia, use of adjunctive ganglionic blockade and long-term recovery. Stroke. 1986; 17: 1010-5.
    • (1986) Stroke , vol.17 , pp. 1010-1015
    • Grogaard, B.1    Gerdin, B.2    Arfors, K.E.3
  • 28
    • 77958555016 scopus 로고    scopus 로고
    • Role of Rac1 GTPase in NADPH oxidase activation and cognitive impairment following cerebral ischemia in the rat
    • Raz L, Zhang QG, Zhou CF, et al. Role of Rac1 GTPase in NADPH oxidase activation and cognitive impairment following cerebral ischemia in the rat. PLoS ONE. 2010; 5: e12606.
    • (2010) PLoS ONE , vol.5
    • Raz, L.1    Zhang, Q.G.2    Zhou, C.F.3
  • 29
    • 79959362175 scopus 로고    scopus 로고
    • Temporal and sequential changes of glial cells and cytokine expression during neuronal degeneration after transient global ischemia in rats
    • Yasuda Y, Shimoda T, Uno K, et al. Temporal and sequential changes of glial cells and cytokine expression during neuronal degeneration after transient global ischemia in rats. J Neuroinflammation. 2011; 8: 70.
    • (2011) J Neuroinflammation , vol.8 , pp. 70
    • Yasuda, Y.1    Shimoda, T.2    Uno, K.3
  • 30
    • 84859791412 scopus 로고    scopus 로고
    • Inhibition of P2X7 receptor ameliorates transient global cerebral ischemia/reperfusion injury via modulating inflammatory responses in the rat hippocampus
    • Chu K, Yin B, Wang J, et al. Inhibition of P2X7 receptor ameliorates transient global cerebral ischemia/reperfusion injury via modulating inflammatory responses in the rat hippocampus. J Neuroinflammation. 2012; 9: 69.
    • (2012) J Neuroinflammation , vol.9 , pp. 69
    • Chu, K.1    Yin, B.2    Wang, J.3
  • 31
    • 0026470907 scopus 로고
    • Ischemia-induced extracellular release of serotonin plays a role in CA1 neuronal cell death in rats
    • Globus MY, Wester P, Busto R, et al. Ischemia-induced extracellular release of serotonin plays a role in CA1 neuronal cell death in rats. Stroke. 1992; 23: 1595-601.
    • (1992) Stroke , vol.23 , pp. 1595-1601
    • Globus, M.Y.1    Wester, P.2    Busto, R.3
  • 32
    • 0034554854 scopus 로고    scopus 로고
    • Impaired recognition memory in rats after damage to the hippocampus
    • Clark RE, Zola SM, Squire LR. Impaired recognition memory in rats after damage to the hippocampus. J Neurosci. 2000; 20: 8853-60.
    • (2000) J Neurosci , vol.20 , pp. 8853-8860
    • Clark, R.E.1    Zola, S.M.2    Squire, L.R.3
  • 33
  • 34
    • 33646851212 scopus 로고    scopus 로고
    • Hippocampal lesion prevents spatial relational learning in adult macaque monkeys
    • Lavenex PB, Amaral DG, Lavenex P. Hippocampal lesion prevents spatial relational learning in adult macaque monkeys. J Neurosci. 2006; 26: 4546-58.
    • (2006) J Neurosci , vol.26 , pp. 4546-4558
    • Lavenex, P.B.1    Amaral, D.G.2    Lavenex, P.3
  • 35
    • 77953551558 scopus 로고    scopus 로고
    • Focal lesions of human hippocampal CA1 neurons in transient global amnesia impair place memory
    • Bartsch T, Schonfeld R, Muller FJ, et al. Focal lesions of human hippocampal CA1 neurons in transient global amnesia impair place memory. Science. 2010; 328: 1412-5.
    • (2010) Science , vol.328 , pp. 1412-1415
    • Bartsch, T.1    Schonfeld, R.2    Muller, F.J.3
  • 36
    • 0024350190 scopus 로고
    • Elimination of the delayed postischemic energy deficit in cerebral cortex and hippocampus of aged rats with a dried, deproteinized blood extract (Actovegin)
    • Hoyer S, Betz K. Elimination of the delayed postischemic energy deficit in cerebral cortex and hippocampus of aged rats with a dried, deproteinized blood extract (Actovegin). Arch Gerontol Geriatr. 1989; 9: 181-92.
    • (1989) Arch Gerontol Geriatr , vol.9 , pp. 181-192
    • Hoyer, S.1    Betz, K.2
  • 37
    • 64549158079 scopus 로고    scopus 로고
    • Genomic and biochemical approaches in the discovery of mechanisms for selective neuronal vulnerability to oxidative stress
    • Wang X, Zaidi A, Pal R, et al. Genomic and biochemical approaches in the discovery of mechanisms for selective neuronal vulnerability to oxidative stress. BMC Neurosci. 2009; 10: 12.
    • (2009) BMC Neurosci , vol.10 , pp. 12
    • Wang, X.1    Zaidi, A.2    Pal, R.3
  • 38
    • 0026080976 scopus 로고
    • Nature of enhanced mitochondrial oxidative metabolism by a calf blood extract
    • Kuninaka T, Senga Y, Senga H, et al. Nature of enhanced mitochondrial oxidative metabolism by a calf blood extract. J Cell Physiol. 1991; 146: 148-55.
    • (1991) J Cell Physiol , vol.146 , pp. 148-155
    • Kuninaka, T.1    Senga, Y.2    Senga, H.3
  • 39
    • 53549096496 scopus 로고    scopus 로고
    • Experience in the use of Actovegin in the treatment of patients with cognitive disorders in the acute period of stroke
    • Derev'yannykh EA, Bel'skaya GN, Knoll EA, et al. Experience in the use of Actovegin in the treatment of patients with cognitive disorders in the acute period of stroke. Neurosci Behav Physiol. 2008; 38: 873-5.
    • (2008) Neurosci Behav Physiol , vol.38 , pp. 873-875
    • Derev'yannykh, E.A.1    Bel'skaya, G.N.2    Knoll, E.A.3
  • 40
    • 84870538997 scopus 로고    scopus 로고
    • Sildenafil provides sustained neuroprotection in the absence of learning recovery following the 4-vessel occlusion/internal carotid artery model of chronic cerebral hypoperfusion in middle-aged rats
    • Dias Fiuza FE, Valerio RC, Cypriano PE, et al. Sildenafil provides sustained neuroprotection in the absence of learning recovery following the 4-vessel occlusion/internal carotid artery model of chronic cerebral hypoperfusion in middle-aged rats. Brain Res Bull. 2013; 90: 58-65.
    • (2013) Brain Res Bull , vol.90 , pp. 58-65
    • Dias Fiuza, F.E.1    Valerio, R.C.2    Cypriano, P.E.3


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