LncRNA H19/miR-675 axis represses prostate cancer metastasis by targeting TGFBI

FEBS Journal

Volumn 281, Issue 16, 2014, Pages 3766-3775

  Zhu, Miaojun ^a,b   Chen, Qin ^b   Liu, Xin ^b   Sun, Qian ^b   Zhao, Xian ^b   Deng, Rong ^b   Wang, Yanli ^b   Huang, Jian ^b   Xu, Ming ^a   Yan, Jianshe ^b   Yu, Jianxiu ^a,b  

^a School of Medicine   (China)

^b SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

lncRNA H19; miR 675; prostate cancer; TGFBI; tumor metastasis

Indexed keywords

MESSENGER RNA; MICRORNA; MICRORNA 675; RNA H19; TRANSFORMING GROWTH FACTOR BETA INDUCED PROTEIN; TUMOR PROTEIN; UNCLASSIFIED DRUG;

3' UNTRANSLATED REGION; ARTICLE; BINDING SITE; CELL MIGRATION; CELL MOTILITY; CONTROLLED STUDY; GENE OVEREXPRESSION; GENE REPRESSION; GENE SEQUENCE; GENE TARGETING; HUMAN; HUMAN CELL; LUCIFERASE ASSAY; MALE; METASTASIS; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROSTATE CANCER; PROSTATE CANCER CELL LINE; PROTEIN EXPRESSION; TGFBI GENE; TUMOR GENE;

LNCRNA H19; MIR-675; PROSTATE CANCER; TGFBI; TUMOR METASTASIS;

3' UNTRANSLATED REGIONS; BASE SEQUENCE; BINDING SITES; BONE NEOPLASMS; CELL LINE, TUMOR; CELL MOVEMENT; EPITHELIAL CELLS; EXTRACELLULAR MATRIX PROTEINS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MALE; MICRORNAS; PROSTATE; PROSTATIC NEOPLASMS; RNA INTERFERENCE; RNA, LONG NONCODING; RNA, MESSENGER; TRANSFORMING GROWTH FACTOR BETA;

EID: 84906791656     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/febs.12902     Document Type: Article

References (39)

1. Siegel R, DeSantis C, Virgo K, Stein K, Mariotto A, Smith T, Cooper D, Gansler T, Lerro C, Fedewa S, et al,. (2012) Cancer treatment and survivorship statistics, 2012. CA Cancer J Clin 62, 220-241.
2. Sturge J, Caley MP, &, Waxman J, (2011) Bone metastasis in prostate cancer: emerging therapeutic strategies. Nat Rev Clin Oncol 8, 357-368.
3. Lustig-Yariv O, Schulze E, Komitowski D, Erdmann V, Schneider T, De Groot N, &, Hochberg A, (1997) The expression of the imprinted genes H19 and IGF-2 in choriocarcinoma cell lines. Is H19 a tumor suppressor gene? Oncogene 15, 169-177.
4. Ariel I, Sughayer M, Fellig Y, Pizov G, Ayesh S, Podeh D, Libdeh B, Levy C, Birman T, &, Tykocinski M, (2000) The imprinted H19 gene is a marker of early recurrence in human bladder carcinoma. Mol Pathol 53, 320-323.
5. Gabory A, Ripoche M-A, Le Digarcher A, Watrin F, Ziyyat A, Forné T, Jammes H, Ainscough JF, Surani MA, &, Journot L, (2009) H19 acts as a trans regulator of the imprinted gene network controlling growth in mice. Development 136, 3413-3421.
6. Dao D, Walsh CP, Yuan L, Gorelov D, Feng L, Hensle T, Nisen P, Yamashiro DJ, Bestor TH, &, Tycko B, (1999) Multipoint analysis of human chromosome 11p15/mouse distal chromosome 7: inclusion of H19/IGF2 in the minimal WT2 region, gene specificity of H19 silencing in Wilms' tumorigenesis and methylation hyper-dependence of H19 imprinting. Human Mol Genet 8, 1337-1352.
7. Juan V, Crain C, &, Wilson C, (2000) Evidence for evolutionarily conserved secondary structure in the H19 tumor suppressor RNA. Nucleic Acids Res 28, 1221-1227.
8. Yoshimizu T, Miroglio A, Ripoche M-A, Gabory A, Vernucci M, Riccio A, Colnot S, Godard C, Terris B, &, Jammes H, (2008) The H19 locus acts in vivo as a tumor suppressor. Proc Natl Acad Sci USA 105, 12417-12422.
9. Yang F, Bi J, Xue X, Zheng L, Zhi K, Hua J, &, Fang G, (2012) Up-regulated long non-coding RNA H19 contributes to proliferation of gastric cancer cells. FEBS J 279, 3159-3165.
10. Kallen AN, Zhou X-B, Xu J, Qiao C, Ma J, Yan L, Lu L, Liu C, Yi J-S, &, Zhang H, (2013) The imprinted H19 lncRNA antagonizes let-7 microRNAs. Mol Cell 52, 101-112.
11. Cai X, &, Cullen BR, (2007) The imprinted H19 noncoding RNA is a primary microRNA precursor. RNA 13, 313-316.
12. Tsang WP, Ng EK, Ng SS, Jin H, Yu J, Sung JJ, &, Kwok TT, (2010) Oncofetal H19-derived miR-675 regulates tumor suppressor RB in human colorectal cancer. Carcinogenesis 31, 350-358.
13. Keniry A, Oxley D, Monnier P, Kyba M, Dandolo L, Smits G, &, Reik W, (2012) The H19 lincRNA is a developmental reservoir of miR-675 that suppresses growth and Igf1r. Nat Cell Biol 14, 659-665.
14. Bae VL, Jackson-Cook CK, Brothman AR, Maygarden SJ, &, Ware JL, (1994) Tumorigenicity of SV40 T antigen immortalized human prostate epithelial cells: association with decreased epidermal growth factor receptor (EGFR) expression. Int J Cancer 58, 721-729.
15. Bae VL, Jackson-Cook CK, Maygarden SJ, Plymate SR, Chen J, &, Ware JL, (1998) Metastatic sublines of an SV40 large T antigen immortalized human prostate epithelial cell line. Prostate 34, 275-282.
16. Liu X, Chen Q, Yan J, Wang Y, Zhu C, Chen C, Zhao X, Xu M, Sun Q, &, Deng R, (2013) MiRNA-296-3p-ICAM-1 axis promotes metastasis of prostate cancer by possible enhancing survival of natural killer cell-resistant circulating tumour cells. Cell Death Dis 4, e928.
17. Ke N, Wang X, Xu X, &, Abassi YA, (2011) The xCELLigence system for real-time and label-free monitoring of cell viability. Methods Mol Biol 740, 33-43.
18. Qu Y, Chen Q, Lai X, Zhu C, Chen C, Zhao X, Deng R, Xu M, Yuan H, Wang Y, et al,. (2014) SUMOylation of Grb2 enhances the ERK activity by increasing its binding with Sos1. Mol Cancer 13, 95.
19. Lustig O, Ariel I, Ilan J, Lev-Lehman E, De-Groot N, &, Hochberg A, (1994) Expression of the imprinted gene H19 in the human fetus. Mol Reprod Dev 38, 239-246.
20. Ohlsson R, Hedborg F, Holmgren L, Walsh C, &, Ekstrom T, (1994) Overlapping patterns of IGF2 and H19 expression during human development: biallelic IGF2 expression correlates with a lack of H19 expression. Development 120, 361-368.
21. Doucrasy S, Coll J, Barrois M, Joubel A, Prost S, Dozier C, Stéhelin D, &, Riou G, (1993) Expression of the human fetal BAC H19 gene in invasive cancers. Int J Oncol 2, 753-758.
22. Vennin C, Dahmani F, Spruyt N, &, Adriaenssens E, (2013) Role of long non-coding RNA in cells: example of the H19/IGF2 locus. Adv Biosci Biotechnol 4, 34-44.
23. Smits G, Mungall AJ, Griffiths-Jones S, Smith P, Beury D, Matthews L, Rogers J, Pask AJ, Shaw G, &, VandeBerg JL, (2008) Conservation of the H19 noncoding RNA and H19-IGF2 imprinting mechanism in therians. Nat Genet 40, 971-976.
24. Viswanathan SR, Daley GQ, &, Gregory RI, (2008) Selective blockade of microRNA processing by Lin28. Science 320, 97-100.
25. Krützfeldt J, Rajewsky N, Braich R, Rajeev KG, Tuschl T, Manoharan M, &, Stoffel M, (2005) Silencing of microRNAs in vivo with 'antagomirs'. Nature 438, 685-689.
26. Ameres SL, Horwich MD, Hung J-H, Xu J, Ghildiyal M, Weng Z, &, Zamore PD, (2010) Target RNA-directed trimming and tailing of small silencing RNAs. Science 328, 1534-1539.
27. Ibrahim F, Rymarquis LA, Kim E-J, Becker J, Balassa E, Green PJ, &, Cerutti H, (2010) Uridylation of mature miRNAs and siRNAs by the MUT68 nucleotidyl transferase promotes their degradation in Chlamydomonas. Proc Natl Acad Sci USA 107, 3906-3911.
28. Baccarini A, Chauhan H, Gardner TJ, Jayaprakash AD, Sachidanandam R, &, Brown BD, (2011) Kinetic analysis reveals the fate of a microRNA following target regulation in mammalian cells. Curr Biol 21, 369-376.
29. Bail S, Swerdel M, Liu H, Jiao X, Goff LA, Hart RP, &, Kiledjian M, (2010) Differential regulation of microRNA stability. RNA 16, 1032-1039.
30. Zhang Z, Zou J, Wang G-K, Zhang J-T, Huang S, Qin Y-W, &, Jing Q, (2011) Uracils at nucleotide position 9-11 are required for the rapid turnover of miR-29 family. Nucleic Acids Res 39, 4387-4395.
31. Parry DH, Xu J, &, Ruvkun G, (2007) A whole-genome RNAi screen for C. elegans miRNA pathway genes. Curr Biol 17, 2013-2022.
32. Zhang X, Fournier MV, Ware JL, Bissell MJ, Yacoub A, &, Zehner ZE, (2009) Inhibition of vimentin or beta1 integrin reverts morphology of prostate tumor cells grown in laminin-rich extracellular matrix gels and reduces tumor growth in vivo. Mol Cancer Ther 8, 499-508.
33. Skonier J, Neubauer M, Madisen L, Bennett K, Plowman GD, &, Purchio A, (1992) cDNA cloning and sequence analysis of βig-h3, a novel gene induced in a human adenocarcinoma cell line after treatment with transforming growth factor-β. DNA Cell Biol 11, 511-522.
34. Lee JM, Dedhar S, Kalluri R, &, Thompson EW, (2006) The epithelial-mesenchymal transition: new insights in signaling, development, and disease. J Cell Biol 172, 973-981.
35. Hourihan R, O'Sullivan G, &, Morgan J, (2002) Transcriptional gene expression profiles of oesophageal adenocarcinoma and normal oesophageal tissues. Anticancer Res 23, 161-165.
36. Tomioka H, Morita KI, Hasegawa S, &, Omura K, (2006) Gene expression analysis by cDNA microarray in oral squamous cell carcinoma. J Oral Pathol Med 35, 206-211.
37. Lin B, Madan A, Yoon J-G, Fang X, Yan X, Kim T-K, Hwang D, Hood L, &, Foltz G, (2010) Massively parallel signature sequencing and bioinformatics analysis identifies up-regulation of TGFBI and SOX4 in human glioblastoma. PLoS ONE 5, e10210.
38. Ma C, Rong Y, Radiloff DR, Datto MB, Centeno B, Bao S, Cheng AWM, Lin F, Jiang S, &, Yeatman TJ, (2008) Extracellular matrix protein βig-h3/TGFBI promotes metastasis of colon cancer by enhancing cell extravasation. Genes Dev 22, 308-321.
39. Shang D, Liu Y, Yang P, Chen Y, &, Tian Y, (2012) TGFBI-promoted adhesion, migration and invasion of human renal cell carcinoma depends on inactivation of von Hippel-Lindau tumor suppressor. Urology 79, 966.e1-966.e7.