Magnesium-dependent folding of a picornavirus IRES element modulates RNA conformation and eIF4G interaction

FEBS Journal

Volumn 281, Issue 16, 2014, Pages 3685-3700

  Lozano, Gloria ^a   Fernandez, Noemi ^a   Martinez Salas, Encarnacion ^a  

^a UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

Author keywords

eIF4G binding; IRES dependent translation initiation; magnesium ions; RNA structure; SHAPE footprint

Indexed keywords

DIVALENT CATION; INITIATION FACTOR 4G; MAGNESIUM ION; VIRUS RNA;

ACYLATION; ARTICLE; COMPLEX FORMATION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DELETION MUTANT; FOOT AND MOUTH DISEASE VIRUS; INTERNAL RIBOSOME ENTRY SITE; MUTATIONAL ANALYSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PURIFICATION; PROTEIN RNA BINDING; RNA CONFORMATION; RNA FOLDING; RNA SEQUENCE; SEQUENCE ALIGNMENT;

EUKARYOTA; FOOT-AND-MOUTH DISEASE VIRUS; PICORNAVIRIDAE;

EIF4G-BINDING; IRES-DEPENDENT TRANSLATION INITIATION; MAGNESIUM IONS; RNA STRUCTURE; SHAPE FOOTPRINT;

ANIMALS; BASE SEQUENCE; BINDING SITES; CELL LINE; CONSENSUS SEQUENCE; CRICETINAE; EUKARYOTIC INITIATION FACTOR-4G; FOOT-AND-MOUTH DISEASE VIRUS; GENE EXPRESSION REGULATION, VIRAL; INVERTED REPEAT SEQUENCES; MAGNESIUM; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; REGULATORY ELEMENTS, TRANSCRIPTIONAL; RNA FOLDING; RNA, VIRAL;

EID: 84906791016     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/febs.12890     Document Type: Article

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