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Volumn 16, Issue 9, 2014, Pages 1366-1377

Leptospiral outer membrane protein LMB216 is involved in enhancement of phagocytic uptake by macrophages

Author keywords

[No Author keywords available]

Indexed keywords

FIBRONECTIN; OUTER MEMBRANE PROTEIN; PROTEIN LMB216; UNCLASSIFIED DRUG;

EID: 84906789689     PISSN: 14625814     EISSN: 14625822     Source Type: Journal    
DOI: 10.1111/cmi.12296     Document Type: Article
Times cited : (31)

References (49)
  • 1
    • 80052541260 scopus 로고    scopus 로고
    • Pathogenesis of leptospirosis: the influence of genomics
    • Adler, B., Lo, M., Seemann, T., and Murray, G.L. (2011) Pathogenesis of leptospirosis: the influence of genomics. Vet Microbiol.
    • (2011) Vet Microbiol
    • Adler, B.1    Lo, M.2    Seemann, T.3    Murray, G.L.4
  • 2
  • 3
    • 72049128053 scopus 로고    scopus 로고
    • Lp95, a novel leptospiral protein that binds extracellular matrix components and activates e-selectin on endothelial cells
    • Atzingen, M.V., Gomez, R.M., Schattner, M., Pretre, G., Goncales, A.P., de Morais, Z.M., etal. (2009) Lp95, a novel leptospiral protein that binds extracellular matrix components and activates e-selectin on endothelial cells. J Infect 59: 264-276.
    • (2009) J Infect , vol.59 , pp. 264-276
    • Atzingen, M.V.1    Gomez, R.M.2    Schattner, M.3    Pretre, G.4    Goncales, A.P.5    de Morais, Z.M.6
  • 4
    • 0037316303 scopus 로고    scopus 로고
    • A comparison of normalization methods for high density oligonucleotide array data based on variance and bias
    • Bolstad, B.M., Irizarry, R.A., Astrand, M., and Speed, T.P. (2003) A comparison of normalization methods for high density oligonucleotide array data based on variance and bias. Bioinformatics 19: 185-193.
    • (2003) Bioinformatics , vol.19 , pp. 185-193
    • Bolstad, B.M.1    Irizarry, R.A.2    Astrand, M.3    Speed, T.P.4
  • 5
    • 17644368883 scopus 로고    scopus 로고
    • Random insertional mutagenesis of Leptospira interrogans, the agent of leptospirosis, using a mariner transposon
    • Bourhy, P., Louvel, H., Saint Girons, I., and Picardeau, M. (2005) Random insertional mutagenesis of Leptospira interrogans, the agent of leptospirosis, using a mariner transposon. J Bacteriol 187: 3255-3258.
    • (2005) J Bacteriol , vol.187 , pp. 3255-3258
    • Bourhy, P.1    Louvel, H.2    Saint Girons, I.3    Picardeau, M.4
  • 6
    • 84857588385 scopus 로고    scopus 로고
    • Leptospiral immunoglobulin-like proteins interact with human complement regulators factor H, FHL-1, FHR-1, and C4BP
    • Castiblanco-Valencia, M.M., Fraga, T.R., Silva, L.B., Monaris, D., Abreu, P.A., Strobel, S., etal. (2012) Leptospiral immunoglobulin-like proteins interact with human complement regulators factor H, FHL-1, FHR-1, and C4BP. J Infect Dis 205: 995-1004.
    • (2012) J Infect Dis , vol.205 , pp. 995-1004
    • Castiblanco-Valencia, M.M.1    Fraga, T.R.2    Silva, L.B.3    Monaris, D.4    Abreu, P.A.5    Strobel, S.6
  • 7
    • 70149110267 scopus 로고    scopus 로고
    • TLR4- and TLR2-mediated B cell responses control the clearance of the bacterial pathogen, Leptospira interrogans
    • Chassin, C., Picardeau, M., Goujon, J.M., Bourhy, P., Quellard, N., Darche, S., etal. (2009) TLR4- and TLR2-mediated B cell responses control the clearance of the bacterial pathogen, Leptospira interrogans. J Immunol 183: 2669-2677.
    • (2009) J Immunol , vol.183 , pp. 2669-2677
    • Chassin, C.1    Picardeau, M.2    Goujon, J.M.3    Bourhy, P.4    Quellard, N.5    Darche, S.6
  • 8
    • 34248368916 scopus 로고    scopus 로고
    • Physiological osmotic induction of Leptospira interrogans adhesion: LigA and LigB bind extracellular matrix proteins and fibrinogen
    • Choy, H.A., Kelley, M.M., Chen, T.L., Moller, A.K., Matsunaga, J., and Haake, D.A. (2007) Physiological osmotic induction of Leptospira interrogans adhesion: LigA and LigB bind extracellular matrix proteins and fibrinogen. Infect Immun 75: 2441-2450.
    • (2007) Infect Immun , vol.75 , pp. 2441-2450
    • Choy, H.A.1    Kelley, M.M.2    Chen, T.L.3    Moller, A.K.4    Matsunaga, J.5    Haake, D.A.6
  • 9
    • 79951803975 scopus 로고    scopus 로고
    • The multifunctional LigB adhesin binds homeostatic proteins with potential roles in cutaneous infection by pathogenic Leptospira interrogans
    • Choy, H.A., Kelley, M.M., Croda, J., Matsunaga, J., Babbitt, J.T., Ko, A.I., etal. (2011) The multifunctional LigB adhesin binds homeostatic proteins with potential roles in cutaneous infection by pathogenic Leptospira interrogans. PLoS ONE 6: e16879.
    • (2011) PLoS ONE , vol.6
    • Choy, H.A.1    Kelley, M.M.2    Croda, J.3    Matsunaga, J.4    Babbitt, J.T.5    Ko, A.I.6
  • 10
    • 57349178393 scopus 로고    scopus 로고
    • Targeted mutagenesis in pathogenic Leptospira species: disruption of the LigB gene does not affect virulence in animal models of leptospirosis
    • Croda, J., Figueira, C.P., Wunder, E.A., Jr, Santos, C.S., Reis, M.G., Ko, A.I., and Picardeau, M. (2008) Targeted mutagenesis in pathogenic Leptospira species: disruption of the LigB gene does not affect virulence in animal models of leptospirosis. Infect Immun 76: 5826-5833.
    • (2008) Infect Immun , vol.76 , pp. 5826-5833
    • Croda, J.1    Figueira, C.P.2    Wunder Jr., E.A.3    Santos, C.S.4    Reis, M.G.5    Ko, A.I.6    Picardeau, M.7
  • 11
    • 84867602699 scopus 로고    scopus 로고
    • Leptospira interrogans catalase is required for resistance to H2O2 and for virulence
    • Eshghi, A., Lourdault, K., Murray, G.L., Bartpho, T., Sermswan, R.W., Picardeau, M., etal. (2012) Leptospira interrogans catalase is required for resistance to H2O2 and for virulence. Infect Immun 80: 3892-3899.
    • (2012) Infect Immun , vol.80 , pp. 3892-3899
    • Eshghi, A.1    Lourdault, K.2    Murray, G.L.3    Bartpho, T.4    Sermswan, R.W.5    Picardeau, M.6
  • 12
    • 79960280198 scopus 로고    scopus 로고
    • Heterologous expression of pathogen-specific genes ligA and ligB in the saprophyte Leptospira biflexa confers enhanced adhesion to cultured cells and fibronectin
    • Figueira, C.P., Croda, J., Choy, H.A., Haake, D.A., Reis, M.G., Ko, A.I., and Picardeau, M. (2011) Heterologous expression of pathogen-specific genes ligA and ligB in the saprophyte Leptospira biflexa confers enhanced adhesion to cultured cells and fibronectin. BMC Microbiol 11: 129.
    • (2011) BMC Microbiol , vol.11 , pp. 129
    • Figueira, C.P.1    Croda, J.2    Choy, H.A.3    Haake, D.A.4    Reis, M.G.5    Ko, A.I.6    Picardeau, M.7
  • 13
    • 0033910411 scopus 로고    scopus 로고
    • Spirochaetal lipoproteins and pathogenesis
    • Haake, D.A. (2000) Spirochaetal lipoproteins and pathogenesis. Microbiology 146 (Part 7): 1491-1504.
    • (2000) Microbiology , vol.146 , Issue.PART 7 , pp. 1491-1504
    • Haake, D.A.1
  • 14
    • 79954417801 scopus 로고    scopus 로고
    • Characterization of the immunogenic and antigenic potential of putative lipoproteins from Leptospira interrogans
    • Hartwig, D.D., Seixas, F.K., Cerqueira, G.M., McBride, A.J., and Dellagostin, O.A. (2011) Characterization of the immunogenic and antigenic potential of putative lipoproteins from Leptospira interrogans. Curr Microbiol 62: 1337-1341.
    • (2011) Curr Microbiol , vol.62 , pp. 1337-1341
    • Hartwig, D.D.1    Seixas, F.K.2    Cerqueira, G.M.3    McBride, A.J.4    Dellagostin, O.A.5
  • 15
    • 0025049546 scopus 로고
    • Neutrophil bactericidal activity against Staphylococcus aureus adherent on biological surfaces. Surface-bound extracellular matrix proteins activate intracellular killing by oxygen-dependent and -independent mechanisms
    • Hermann, M., Jaconi, M.E., Dahlgren, C., Waldvogel, F.A., Stendahl, O., and Lew, D.P. (1990) Neutrophil bactericidal activity against Staphylococcus aureus adherent on biological surfaces. Surface-bound extracellular matrix proteins activate intracellular killing by oxygen-dependent and -independent mechanisms. J Clin Invest 86: 942-951.
    • (1990) J Clin Invest , vol.86 , pp. 942-951
    • Hermann, M.1    Jaconi, M.E.2    Dahlgren, C.3    Waldvogel, F.A.4    Stendahl, O.5    Lew, D.P.6
  • 17
    • 79953700573 scopus 로고    scopus 로고
    • UafB is a serine-rich repeat adhesin of Staphylococcus saprophyticus that mediates binding to fibronectin, fibrinogen and human uroepithelial cells
    • King, N.P., Beatson, S.A., Totsika, M., Ulett, G.C., Alm, R.A., Manning, P.A., and Schembri, M.A. (2011) UafB is a serine-rich repeat adhesin of Staphylococcus saprophyticus that mediates binding to fibronectin, fibrinogen and human uroepithelial cells. Microbiology 157: 1161-1175.
    • (2011) Microbiology , vol.157 , pp. 1161-1175
    • King, N.P.1    Beatson, S.A.2    Totsika, M.3    Ulett, G.C.4    Alm, R.A.5    Manning, P.A.6    Schembri, M.A.7
  • 18
    • 70349269503 scopus 로고    scopus 로고
    • Leptospira: the dawn of the molecular genetics era for an emerging zoonotic pathogen
    • Ko, A.I., Goarant, C., and Picardeau, M. (2009) Leptospira: the dawn of the molecular genetics era for an emerging zoonotic pathogen. Nat Rev Microbiol 7: 736-747.
    • (2009) Nat Rev Microbiol , vol.7 , pp. 736-747
    • Ko, A.I.1    Goarant, C.2    Picardeau, M.3
  • 19
    • 1842456788 scopus 로고    scopus 로고
    • Leptospiral immunoglobulin-like proteins elicit protective immunity
    • Koizumi, N., and Watanabe, H. (2004) Leptospiral immunoglobulin-like proteins elicit protective immunity. Vaccine 22: 1545-1552.
    • (2004) Vaccine , vol.22 , pp. 1545-1552
    • Koizumi, N.1    Watanabe, H.2
  • 20
    • 1942535754 scopus 로고    scopus 로고
    • Structure of a thrombospondin C-terminal fragment reveals a novel calcium core in the type 3 repeats
    • Kvansakul, M., Adams, J.C., and Hohenester, E. (2004) Structure of a thrombospondin C-terminal fragment reveals a novel calcium core in the type 3 repeats. EMBO J 23: 1223-1233.
    • (2004) EMBO J , vol.23 , pp. 1223-1233
    • Kvansakul, M.1    Adams, J.C.2    Hohenester, E.3
  • 21
    • 85047688053 scopus 로고    scopus 로고
    • FlaA proteins in Leptospira interrogans are essential for motility and virulence but are not required for formation of the flagellum sheath
    • Lambert, A., Picardeau, M., Haake, D.A., Sermswan, R.W., Srikram, A., Adler, B., and Murray, G.A. (2012) FlaA proteins in Leptospira interrogans are essential for motility and virulence but are not required for formation of the flagellum sheath. Infect Immun 80: 2019-2025.
    • (2012) Infect Immun , vol.80 , pp. 2019-2025
    • Lambert, A.1    Picardeau, M.2    Haake, D.A.3    Sermswan, R.W.4    Srikram, A.5    Adler, B.6    Murray, G.A.7
  • 23
    • 36849009713 scopus 로고    scopus 로고
    • Comparison of invasion of fibroblasts and macrophages by high- and low-virulence Leptospira strains: colonization of the host-cell nucleus and induction of necrosis by the virulent strain
    • Li, L., Ojcius, D.M., and Yan, J. (2007) Comparison of invasion of fibroblasts and macrophages by high- and low-virulence Leptospira strains: colonization of the host-cell nucleus and induction of necrosis by the virulent strain. Arch Microbiol 188: 591-598.
    • (2007) Arch Microbiol , vol.188 , pp. 591-598
    • Li, L.1    Ojcius, D.M.2    Yan, J.3
  • 24
    • 77952357124 scopus 로고    scopus 로고
    • Replication or death: distinct fates of pathogenic Leptospira strain Lai within macrophages of human or mouse origin
    • Li, S., Ojcius, D.M., Liao, S., Li, L., Xue, F., Dong, H., and Yan, J. (2010) Replication or death: distinct fates of pathogenic Leptospira strain Lai within macrophages of human or mouse origin. Innate Immun 16: 80-92.
    • (2010) Innate Immun , vol.16 , pp. 80-92
    • Li, S.1    Ojcius, D.M.2    Liao, S.3    Li, L.4    Xue, F.5    Dong, H.6    Yan, J.7
  • 25
    • 73449089074 scopus 로고    scopus 로고
    • Inactivation of the fliY gene encoding a flagellar motor switch protein attenuates mobility and virulence of Leptospira interrogans strain Lai
    • Liao, S., Sun, A., Ojcius, D.M., Wu, S., Zhao, J., and Yan, J. (2009) Inactivation of the fliY gene encoding a flagellar motor switch protein attenuates mobility and virulence of Leptospira interrogans strain Lai. BMC Microbiol 9: 253.
    • (2009) BMC Microbiol , vol.9 , pp. 253
    • Liao, S.1    Sun, A.2    Ojcius, D.M.3    Wu, S.4    Zhao, J.5    Yan, J.6
  • 26
    • 70349152999 scopus 로고    scopus 로고
    • A novel fibronectin type III module binding motif identified on C-terminus of Leptospira immunoglobulin-like protein, LigB
    • Lin, Y.P., Greenwood, A., Yan, W., Nicholson, L.K., Sharma, Y., McDonough, S.P., and Chang, Y.F. (2009) A novel fibronectin type III module binding motif identified on C-terminus of Leptospira immunoglobulin-like protein, LigB. Biochem Biophys Res Commun 389: 57-62.
    • (2009) Biochem Biophys Res Commun , vol.389 , pp. 57-62
    • Lin, Y.P.1    Greenwood, A.2    Yan, W.3    Nicholson, L.K.4    Sharma, Y.5    McDonough, S.P.6    Chang, Y.F.7
  • 27
    • 77955295092 scopus 로고    scopus 로고
    • The terminal immunoglobulin-like repeats of LigA and LigB of Leptospira enhance their binding to gelatin binding domain of fibronectin and host cells
    • Lin, Y.P., McDonough, S.P., Sharma, Y., and Chang, Y.F. (2010) The terminal immunoglobulin-like repeats of LigA and LigB of Leptospira enhance their binding to gelatin binding domain of fibronectin and host cells. PLoS ONE 5: e11301.
    • (2010) PLoS ONE , vol.5
    • Lin, Y.P.1    McDonough, S.P.2    Sharma, Y.3    Chang, Y.F.4
  • 28
    • 33749259255 scopus 로고    scopus 로고
    • Effects of temperature on gene expression patterns in Leptospira interrogans serovar Lai as assessed by whole-genome microarrays
    • Lo, M., Bulach, D.M., Powell, D.R., Haake, D.A., Matsunaga, J., Paustian, M.L., etal. (2006) Effects of temperature on gene expression patterns in Leptospira interrogans serovar Lai as assessed by whole-genome microarrays. Infect Immun 74: 5848-5859.
    • (2006) Infect Immun , vol.74 , pp. 5848-5859
    • Lo, M.1    Bulach, D.M.2    Powell, D.R.3    Haake, D.A.4    Matsunaga, J.5    Paustian, M.L.6
  • 29
    • 10744230722 scopus 로고    scopus 로고
    • Pathogenic Leptospira species express surface-exposed proteins belonging to the bacterial immunoglobulin superfamily
    • Matsunaga, J., Barocchi, M.A., Croda, J., Young, T.A., Sanchez, Y., Siqueira, I., etal. (2003) Pathogenic Leptospira species express surface-exposed proteins belonging to the bacterial immunoglobulin superfamily. Mol Microbiol 49: 929-945.
    • (2003) Mol Microbiol , vol.49 , pp. 929-945
    • Matsunaga, J.1    Barocchi, M.A.2    Croda, J.3    Young, T.A.4    Sanchez, Y.5    Siqueira, I.6
  • 30
    • 0031035320 scopus 로고    scopus 로고
    • Invasion of Vero cells and induction of apoptosis in macrophages by pathogenic Leptospira interrogans are correlated with virulence
    • Merien, F., Baranton, G., and Perolat, P. (1997) Invasion of Vero cells and induction of apoptosis in macrophages by pathogenic Leptospira interrogans are correlated with virulence. Infect Immun 65: 729-738.
    • (1997) Infect Immun , vol.65 , pp. 729-738
    • Merien, F.1    Baranton, G.2    Perolat, P.3
  • 31
    • 84870254664 scopus 로고    scopus 로고
    • Vascular binding of a pathogen under shear force through mechanistically distinct sequential interactions with host macromolecules
    • Moriarty, T.J., Shi, M., Lin, Y.P., Ebady, R., Zhou, H., Odisho, T., etal. (2012) Vascular binding of a pathogen under shear force through mechanistically distinct sequential interactions with host macromolecules. Mol Microbiol 86: 1116-1131.
    • (2012) Mol Microbiol , vol.86 , pp. 1116-1131
    • Moriarty, T.J.1    Shi, M.2    Lin, Y.P.3    Ebady, R.4    Zhou, H.5    Odisho, T.6
  • 32
    • 84872486407 scopus 로고    scopus 로고
    • The lipoprotein LipL32, an enigma of leptospiral biology
    • Murray, G.L. (2013) The lipoprotein LipL32, an enigma of leptospiral biology. Vet Microbiol 162: 305-314.
    • (2013) Vet Microbiol , vol.162 , pp. 305-314
    • Murray, G.L.1
  • 33
    • 45849127235 scopus 로고    scopus 로고
    • Leptospira interrogans requires a functional heme oxygenase to scavenge iron from hemoglobin
    • Murray, G.L., Ellis, K.M., Lo, M., and Adler, B. (2008) Leptospira interrogans requires a functional heme oxygenase to scavenge iron from hemoglobin. Microbes Infect 10: 791-797.
    • (2008) Microbes Infect , vol.10 , pp. 791-797
    • Murray, G.L.1    Ellis, K.M.2    Lo, M.3    Adler, B.4
  • 35
    • 62449313550 scopus 로고    scopus 로고
    • Major surface protein LipL32 is not required for either acute or chronic infection with Leptospira interrogans
    • Murray, G.L., Srikram, A., Hoke, D.E., Wunder, E.A., Jr, Henry, R., Lo, M., etal. (2009b) Major surface protein LipL32 is not required for either acute or chronic infection with Leptospira interrogans. Infect Immun 77: 952-958.
    • (2009) Infect Immun , vol.77 , pp. 952-958
    • Murray, G.L.1    Srikram, A.2    Hoke, D.E.3    Wunder Jr., E.A.4    Henry, R.5    Lo, M.6
  • 37
    • 0036840589 scopus 로고    scopus 로고
    • Cloning and molecular characterization of an immunogenic LigA protein of Leptospira interrogans
    • Palaniappan, R.U., Chang, Y.F., Jusuf, S.S., Artiushin, S., Timoney, J.F., McDonough, S.P., etal. (2002) Cloning and molecular characterization of an immunogenic LigA protein of Leptospira interrogans. Infect Immun 70: 5924-5930.
    • (2002) Infect Immun , vol.70 , pp. 5924-5930
    • Palaniappan, R.U.1    Chang, Y.F.2    Jusuf, S.S.3    Artiushin, S.4    Timoney, J.F.5    McDonough, S.P.6
  • 38
    • 80355136058 scopus 로고    scopus 로고
    • Immuno-fluorescence assay of leptospiral surface-exposed proteins
    • pii: 2805. doi:10.3791/2805
    • Pinne, M., and Haake, D. (2011) Immuno-fluorescence assay of leptospiral surface-exposed proteins. J Vis Exp (53): pii: 2805. doi:10.3791/2805
    • (2011) J Vis Exp , Issue.53
    • Pinne, M.1    Haake, D.2
  • 39
    • 0037464546 scopus 로고    scopus 로고
    • Unique physiological and pathogenic features of Leptospira interrogans revealed by whole-genome sequencing
    • Ren, S.X., Fu, G., Jiang, X.G., Zeng, R., Miao, Y.G., Xu, H., etal. (2003) Unique physiological and pathogenic features of Leptospira interrogans revealed by whole-genome sequencing. Nature 422: 888-893.
    • (2003) Nature , vol.422 , pp. 888-893
    • Ren, S.X.1    Fu, G.2    Jiang, X.G.3    Zeng, R.4    Miao, Y.G.5    Xu, H.6
  • 41
    • 30744477217 scopus 로고    scopus 로고
    • Lipoprotein computational prediction in spirochaetal genomes
    • Setubal, J.C., Reis, M., Matsunaga, J., and Haake, D.A. (2006) Lipoprotein computational prediction in spirochaetal genomes. Microbiology 152: 113-121.
    • (2006) Microbiology , vol.152 , pp. 113-121
    • Setubal, J.C.1    Reis, M.2    Matsunaga, J.3    Haake, D.A.4
  • 42
    • 79959392159 scopus 로고    scopus 로고
    • Role of fibronectin-binding proteins A and B in in vitro cellular infections and in vivo septic infections by Staphylococcus aureus
    • Shinji, H., Yosizawa, Y., Tajima, A., Iwase, T., Sugimoto, S., Seki, K., and Mizunoe, Y. (2011) Role of fibronectin-binding proteins A and B in in vitro cellular infections and in vivo septic infections by Staphylococcus aureus. Infect Immun 79: 2215-2223.
    • (2011) Infect Immun , vol.79 , pp. 2215-2223
    • Shinji, H.1    Yosizawa, Y.2    Tajima, A.3    Iwase, T.4    Sugimoto, S.5    Seki, K.6    Mizunoe, Y.7
  • 43
    • 43149110212 scopus 로고    scopus 로고
    • Leptospira interrogans endostatin-like outer membrane proteins bind host fibronectin, laminin and regulators of complement
    • Stevenson, B., Choy, H.A., Pinne, M., Rotondi, M.L., Miller, M.C., Demoll, E., etal. (2007) Leptospira interrogans endostatin-like outer membrane proteins bind host fibronectin, laminin and regulators of complement. PLoS ONE 2: e1188.
    • (2007) PLoS ONE , vol.2
    • Stevenson, B.1    Choy, H.A.2    Pinne, M.3    Rotondi, M.L.4    Miller, M.C.5    Demoll, E.6
  • 44
    • 0037842810 scopus 로고    scopus 로고
    • Multiplex PCR assay for identification of human diarrheagenic Escherichia coli
    • Toma, C., Lu, Y., Higa, N., Nakasone, N., Chinen, I., Baschkier, A., etal. (2003) Multiplex PCR assay for identification of human diarrheagenic Escherichia coli. J Clin Microbiol 41: 2669-2671.
    • (2003) J Clin Microbiol , vol.41 , pp. 2669-2671
    • Toma, C.1    Lu, Y.2    Higa, N.3    Nakasone, N.4    Chinen, I.5    Baschkier, A.6
  • 45
    • 80054112939 scopus 로고    scopus 로고
    • Characteristic features of intracellular pathogenic Leptospira in infected murine macrophages
    • Toma, C., Okura, N., Takayama, C., and Suzuki, T. (2011) Characteristic features of intracellular pathogenic Leptospira in infected murine macrophages. Cell Microbiol 13: 1783-1792.
    • (2011) Cell Microbiol , vol.13 , pp. 1783-1792
    • Toma, C.1    Okura, N.2    Takayama, C.3    Suzuki, T.4
  • 46
    • 84857938819 scopus 로고    scopus 로고
    • Antibodies to a novel leptospiral protein, LruC, in the eye fluids and sera of horses with Leptospira-associated uveitis
    • Verma, A., Matsunaga, J., Artiushin, S., Pinne, M., Houwers, D.J., Haake, D.A., etal. (2012) Antibodies to a novel leptospiral protein, LruC, in the eye fluids and sera of horses with Leptospira-associated uveitis. Clin Vaccine Immunol 19: 452-456.
    • (2012) Clin Vaccine Immunol , vol.19 , pp. 452-456
    • Verma, A.1    Matsunaga, J.2    Artiushin, S.3    Pinne, M.4    Houwers, D.J.5    Haake, D.A.6
  • 47
    • 31844440188 scopus 로고    scopus 로고
    • Toll-like receptor 4 protects against lethal Leptospira interrogans serovar icterohaemorrhagiae infection and contributes to in vivo control of leptospiral burden
    • Viriyakosol, S., Matthias, M.A., Swancutt, M.A., Kirkland, T.N., and Vinetz, J.M. (2006) Toll-like receptor 4 protects against lethal Leptospira interrogans serovar icterohaemorrhagiae infection and contributes to in vivo control of leptospiral burden. Infect Immun 74: 887-895.
    • (2006) Infect Immun , vol.74 , pp. 887-895
    • Viriyakosol, S.1    Matthias, M.A.2    Swancutt, M.A.3    Kirkland, T.N.4    Vinetz, J.M.5
  • 48
    • 84862795039 scopus 로고    scopus 로고
    • The mammalian cell entry (Mce) protein of pathogenic Leptospira species is responsible for RGD motif-dependent infection of cells and animals
    • Zhang, L., Zhang, C., Ojcius, D.M., Sun, D., Zhao, J., Lin, X., etal. (2012) The mammalian cell entry (Mce) protein of pathogenic Leptospira species is responsible for RGD motif-dependent infection of cells and animals. Mol Microbiol 83: 1006-1023.
    • (2012) Mol Microbiol , vol.83 , pp. 1006-1023
    • Zhang, L.1    Zhang, C.2    Ojcius, D.M.3    Sun, D.4    Zhao, J.5    Lin, X.6
  • 49
    • 79961209179 scopus 로고    scopus 로고
    • Comparative proteogenomic analysis of the Leptospira interrogans virulence-attenuated strain IPAV against the pathogenic strain 56601
    • Zhong, Y., Chang, X., Cao, X.J., Zhang, Y., Zheng, H., Zhu, Y., etal. (2011) Comparative proteogenomic analysis of the Leptospira interrogans virulence-attenuated strain IPAV against the pathogenic strain 56601. Cell Res 21: 1210-1229.
    • (2011) Cell Res , vol.21 , pp. 1210-1229
    • Zhong, Y.1    Chang, X.2    Cao, X.J.3    Zhang, Y.4    Zheng, H.5    Zhu, Y.6


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