Breakthrough discoveries in drug delivery technologies: The next 30 years

Journal of Controlled Release

Volumn 190, Issue , 2014, Pages 9-14

  Brambilla, Davide ^a   Luciani, Paola ^a   Leroux, Jean Christophe ^a  

^a ETH ZURICH   (Switzerland)

Author keywords

Cell therapy; EPR effect; Microchips; Microneedles; Nanoparticles; Oncolytic viruses

Indexed keywords

NANOPARTICLES; VIRUSES;

CELL THERAPY; EPR EFFECT; MICROCHIPS; MICRONEEDLES; ONCOLYTIC VIRUS;

DRUG DELIVERY;

ONCOLYTIC VIRUS; DELAYED RELEASE FORMULATION; NANOPARTICLE;

BIOREACTOR; DRUG DELIVERY SYSTEM; ENHANCED PERMEATION AND RETENTION; HUMAN; IN VIVO STUDY; MEMBRANE VESICLE; NANOMEDICINE; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; REVIEW; TRANSDERMAL DRUG ADMINISTRATION; DELAYED RELEASE FORMULATION; FORECASTING; MEDICAL RESEARCH; MEMBRANE MICROPARTICLE; ONCOLYTIC VIROTHERAPY; TRENDS;

BIOMEDICAL RESEARCH; CELL-DERIVED MICROPARTICLES; DELAYED-ACTION PREPARATIONS; DRUG DELIVERY SYSTEMS; FORECASTING; HUMANS; NANOPARTICLES; ONCOLYTIC VIROTHERAPY;

EID: 84906788669     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2014.03.056     Document Type: Review

References (76)

1. Z. Liu, J.T. Robinson, X.M. Sun, and H.J. Dai PEGylated nanographene oxide for delivery of water-insoluble cancer drugs J. Am. Chem. Soc. 130 2008 10876 10877
2. X.M. Qian, X.H. Peng, D.O. Ansari, Q. Yin-Goen, G.Z. Chen, D.M. Shin, L. Yang, A.N. Young, M.D. Wang, and S.M. Nie In vivo tumor targeting and spectroscopic detection with surface-enhanced Raman nanoparticle tags Nat. Biotechnol. 26 2008 83 90
3. X.M. Sun, Z. Liu, K. Welsher, J.T. Robinson, A. Goodwin, S. Zaric, and H.J. Dai Nano-graphene oxide for cellular imaging and drug delivery Nano Res. 1 2008 203 212
4. P. Horcajada, T. Chalati, C. Serre, B. Gillet, C. Sebrie, T. Baati, J.F. Eubank, D. Heurtaux, P. Clayette, C. Kreuz, J.S. Chang, Y.K. Hwang, V. Marsaud, P.N. Bories, L. Cynober, S. Gil, G. Ferey, P. Couvreur, and R. Gref Porous metal-organic-framework nanoscale carriers as a potential platform for drug delivery and imaging Nat. Mater. 9 2010 172 178
5. M. Liong, J. Lu, M. Kovochich, T. Xia, S.G. Ruehm, A.E. Nel, F. Tamanoi, and J.I. Zink Multifunctional inorganic nanoparticles for imaging, targeting, and drug delivery ACS Nano 2 2008 889 896
6. J. Nicolas, S. Mura, D. Brambilla, N. Mackiewicz, and P. Couvreur Design, functionalization strategies and biomedical applications of targeted biodegradable/biocompatible polymer-based nanocarriers for drug delivery Chem. Soc. Rev. 42 2013 1147 1235
7. N.R. Patel, B.S. Pattni, A.H. Abouzeid, and V.P. Torchilin Nanopreparations to overcome multidrug resistance in cancer Adv. Drug Deliv. Rev. 65 2013 1748 1762
8. R. van der Meel, L.J.C. Vehmeijer, R.J. Kok, G. Storm, and E.V.B. van Gaal Ligand-targeted particulate nanomedicines undergoing clinical evaluation: current status Adv. Drug Deliv. Rev. 64 2013 1284 1298
9. Y. Barenholz Doxil® - the first FDA-approved nano-drug: lessons learned J. Control. Release 160 2012 117 134
10. R. Duncan, and R. Gaspar Nanomedicine(s) under the microscope Mol. Pharm. 8 2011 2101 2141
11. A.T. Florence Pharmaceutical Nanotechnology: more than size ten topics for research Int. J. Pharm. 339 2007 1 2 (Pubitemid 46977614)
12. V.J. Venditto, and F.C. Szoka Jr. Cancer nanomedicines: so many papers and so few drugs! Adv. Drug Deliv. Rev. 65 2013 80 88
13. D.L. Stirland, J.W. Nichols, S. Miura, and Y.H. Bae Mind the gap: a survey of how cancer drug carriers are susceptible to the gap between research and practice J. Control. Release 172 2013 1045 1064
14. M.S. Gerstel, V.A. Place, Drug delivery device, US Pat. 3964482 (A), 1976.
15. Y. Matsumura, and H. Maeda A new concept for macromolecular therapeutics in cancer-chemotherapy - mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs Cancer Res. 46 1986 6387 6392 (Pubitemid 17221789)
16. T. Lammers, P. Peschke, R. Kuehnlein, V. Subr, K. Ulbriich, J. Debus, P. Huber, W. Hennink, and G. Storm Effect of radiotherapy and hyperthermia on the tumor accumulation of HPMA copolymer-based drug delivery systems J. Control. Release 117 2007 333 341 (Pubitemid 46216581)
17. P. Ruenraroengsak, J.M. Cook, and A.T. Florence Nanosystem drug targeting: facing up to complex realities J. Control. Release 141 2010 265 276
18. K. Park Questions on the role of the EPR effect in tumor targeting J. Control. Release 172 2013 391
19. R.K. Jain Normalizing tumor microenvironment to treat cancer: bench to bedside to biomarkers J. Clin. Oncol. 31 2013 2205 2219
20. S. Stapleton, C. Allen, M. Pintilie, and D.A. Jaffray Tumor perfusion imaging predicts the intra-tumoral accumulation of liposomes J. Control. Release 172 2013 351 357
21. C.J. Li, Y. Miyamoto, Y. Kojima, and H. Maeda Augmentation of tumor delivery of macromolecular drugs with reduced bone-marrow delivery by elevating blood-pressure Br. J. Cancer 67 1993 975 980 (Pubitemid 23147488)
22. M.R. Kano, Y. Bae, C. Iwata, Y. Morishita, M. Yashiro, M. Oka, T. Fujii, A. Komuro, K. Kiyono, M. Kaminishi, K. Hirakawa, Y. Ouchi, N. Nishiyama, K. Kataoka, and K. Miyazono Improvement of cancer-targeting therapy, using nanocarriers for intractable solid tumors by inhibition of TGF-beta signaling Proc. Natl. Acad. Sci. U. S. A. 104 2007 3460 3465 (Pubitemid 46364181)
23. T. Seki, J. Fang, and H. Maeda Enhanced delivery of macromolecular antitumor drugs to tumors by nitroglycerin application Cancer Sci. 100 2009 2426 2430
24. J. Fang, H. Qin, H. Nakamura, K. Tsukigawa, T. Shin, and H. Maeda Carbon monoxide, generated by heme oxygenase-1, mediates the enhanced permeability and retention effect in solid tumors Cancer Sci. 103 2012 535 541
25. C. Godugu, A.R. Patel, R. Doddapaneni, S. Marepally, T. Jackson, and M. Singh Inhalation delivery of Telmisartan enhances intratumoral distribution of nanoparticles in lung cancer models J. Control. Release 172 2013 86 95
26. V.P. Chauhan, T. Stylianopoulos, J.D. Martin, Z. Popovic, O. Chen, W.S. Kamoun, M.G. Bawendi, D. Fukumura, and R.K. Jain Normalization of tumour blood vessels improves the delivery of nanomedicines in a size-dependent manner Nat. Nanotechnol. 7 2012 383 388
27. A.J. Gormley, N. Larson, A. Banisadr, R. Robinson, N. Frazier, A. Ray, and H. Ghandehari Plasmonic photothermal therapy increases the tumor mass penetration of HPMA copolymers J. Control. Release 166 2013 130 138
28. L. Li, T.L.M. ten Hagen, M. Bolkestein, A. Gasselhuber, J. Yatvin, G.C. van Rhoon, A.M.M. Eggermont, D. Haemmerich, and G.A. Koning Improved intratumoral nanoparticle extravasation and penetration by mild hyperthermia J. Control. Release 167 2013 130 137
29. M. Bazan-Peregrino, B. Rifai, R.C. Carlisle, J. Choi, C.D. Arvanitis, L.W. Seymour, and C.C. Coussios Cavitation-enhanced delivery of a replicating oncolytic adenovirus to tumors using focused ultrasound J. Control. Release 169 2013 40 47
30. U. Prabhakar, H. Maeda, R.K. Jain, E.M. Sevick-Muraca, W. Zamboni, O.C. Farokhzad, S.T. Barry, A. Gabizon, P. Grodzinski, and D.C. Blakey Challenges and key considerations of the enhanced permeability and retention effect for nanomedicine drug delivery in oncology Cancer Res. 73 2013 2412 2417
31. E. Mastrobattista Advanced drug delivery in motion Int. J. Pharm. 454 2013 517 520
32. P. Pouponneau, J.-C. Leroux, G. Soulez, L. Gaboury, and S. Martel Co-encapsulation of magnetic nanoparticles and doxorubicin into biodegradable microcarriers for deep tissue targeting by vascular MRI navigation Biomaterials 32 2011 3481 3486
33. C. Sun, J.S.H. Lee, and M. Zhang Magnetic nanoparticles in MR imaging and drug delivery Adv. Drug Deliv. Rev. 60 2008 1252 1265
34. J.L. Arias, L.H. Reddy, M. Othman, B. Gillet, D. Desmaële, F. Zouhiri, F. Dosio, R. Gref, and P. Couvreur Squalene based nanocomposites: a new platform for the design of multifunctional pharmaceutical theragnostics ACS Nano 5 2011 1513 1521
35. A. Yanai, U.O. Hafeli, A.L. Metcalfe, P. Soema, L. Addo, C.Y. Gregory-Evans, K. Po, X.H. Shan, O.L. Moritz, and K. Gregory-Evans Focused magnetic stem cell targeting to the retina using superparamagnetic iron oxide nanoparticles Cell Transplant. 21 2012 1137 1148
36. E.-S. Jang, J.-H. Shin, G. Ren, M.-J. Park, K. Cheng, X. Chen, J.C. Wu, J.B. Sunwoo, and Z. Cheng The manipulation of natural killer cells to target tumor sites using magnetic nanoparticles Biomaterials 33 2012 5584 5592
37. R.A. Rader FDA biopharmaceutical product approvals and trends in 2012 BioProcess Int. 11 2013 18 27
38. S.M. van Dommelen, P. Vader, S. Lakhal, S.A.A. Kooijmans, W.W. van Solinge, M.J.A. Wood, and R.M. Schiffelers Microvesicles and exosomes: opportunities for cell-derived membrane vesicles in drug delivery J. Control. Release 161 2012 635 644
39. L. Alvarez-Erviti, Y.Q. Seow, H.F. Yin, C. Betts, S. Lakhal, and M.J.A. Wood Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes Nat. Biotechnol. 29 2011 341 345
40. D. Sun, X. Zhuang, X. Xiang, Y. Liu, S. Zhang, C. Liu, S. Barnes, W. Grizzle, D. Miller, and H.-G. Zhang A novel nanoparticle drug delivery system: the anti-inflammatory activity of curcumin is enhanced when encapsulated in exosomes Mol. Ther. 18 2010 1606 1614
41. X. Zhuang, X. Xiang, W. Grizzle, D. Sun, S. Zhang, R.C. Axtell, S. Ju, J. Mu, L. Zhang, L. Steinman, D. Miller, and H.-G. Zhang Treatment of brain inflammatory diseases by delivering exosome encapsulated anti-inflammatory drugs from the nasal region to the brain Mol. Ther. 19 2011 1769 1779
42. J.L. Munoz, S.A. Bliss, S.J. Greco, S.H. Ramkissoon, K.L. Ligon, and P. Rameshwar Delivery of functional anti-miR-9 by mesenchymal stem cell-derived exosomes to glioblastoma multiforme cells conferred chemosensitivity Mol. Ther. Nucleic Acids 2 2013 e126
43. S.A.A. Kooijmans, S. Stremersch, K. Braeckmans, S.C. de Smedt, A. Hendrix, M.J.A. Wood, R.M. Schiffelers, K. Raemdonck, and P. Vader Electroporation-induced siRNA precipitation obscures the efficiency of siRNA loading into extracellular vesicles J. Control. Release 172 2013 229 238
44. E.N. Momin, G. Vela, H.A. Zaidi, and A. Quinones-Hinojosa The oncogenic potential of mesenchymal stem cells in the treatment of cancer: directions for future research Curr. Immunol. Rev. 6 2010 137 148
45. J.M. Karp, and G.S.L. Teol Mesenchymal stem cell homing: the devil is in the details Cell Stem Cell 4 2009 206 216
46. K. Shah Mesenchymal stem cells engineered for cancer therapy Adv. Drug Deliv. Rev. 64 2012 739 748
47. L.G. Menon, K. Kelly, H.W. Yang, S.-K. Kim, P.M. Black, and R.S. Carroll Human bone marrow-derived mesenchymal stromal cells expressing S-TRAIL as a cellular delivery vehicle for human glioma therapy Stem Cells 27 2009 2320 2330
48. I.T. Cavarretta, V. Altanerova, M. Matuskova, L. Kucerova, Z. Culig, and C. Altaner Adipose tissue-derived mesenchymal stem cells expressing prodrug-converting enzyme inhibit human prostate tumor growth Mol. Ther. 18 2010 223 231
49. L. Kucerova, V. Altanerova, M. Matuskova, S. Tyciakova, and C. Altaner Adipose tissue-derived human mesenchymal stem cells mediated prodrug cancer gene therapy Cancer Res. 67 2007 6304 6313 (Pubitemid 47037513)
50. R. Cattaneo, T. Miest, E.V. Shashkova, and M.A. Barry Reprogrammed viruses as cancer therapeutics: targeted, armed and shielded Nat. Rev. Microbiol. 6 2008 529 540 (Pubitemid 351850977)
51. C. Willmon, K. Harrington, T. Kottke, R. Prestwich, A. Melcher, and R. Vile Cell carriers for oncolytic viruses: fed ex for cancer therapy Mol. Ther. 17 2009 1667 1676
52. J. Qiao, T. Kottke, C. Willmon, F. Galivo, P. Wongthida, R.M. Diaz, J. Thompson, P. Ryno, G.N. Barber, J. Chester, P. Selby, K. Harrington, A. Melcher, and R.G. Vile Purging metastases in lymphoid organs using a combination of antigen-nonspecific adoptive T cell therapy, oncolytic virotherapy and immunotherapy Nat. Med. 14 2008 37 44
53. D.G. Roy, and J.C. Bell Cell carriers for oncolytic viruses: current challenges and future directions Oncolytic Virother. 2 2013 47 56
54. E.K. Mader, G. Butler, S.C. Dowdy, A. Mariani, K.L. Knutson, M.J. Federspiel, S.J. Russell, E. Galanis, A.B. Dietz, and K.W. Peng Optimizing patient derived mesenchymal stem cells as virus carriers for a phase I clinical trial in ovarian cancer J. Transl. Med. 11 2013 14
55. P. Van Arnum The future of dosage forms Pharm. Technol. 38 2014 28 32
56. J.M. Maloney, S.A. Uhland, B.F. Polito, N.F. Sheppard Jr., C.M. Pelta, and J.T. Santini Jr. Electrothermally activated microchips for implantable drug delivery and biosensing J. Control. Release 109 2005 244 255 (Pubitemid 41737268)
57. Y. Li, R.S. Shawgo, B. Tyler, P.T. Henderson, J.S. Vogel, A. Rosenberg, P.B. Storm, R. Langer, H. Brem, and M.J. Cima In vivo release from a drug delivery MEMS device J. Control. Release 100 2004 211 219 (Pubitemid 39491273)
58. J.T. Santini, M.J. Cima, and R. Langer A controlled-release microchip Nature 397 1999 335 338 (Pubitemid 29061643)
59. R. Farra, N.F. Sheppard Jr., L. McCabe, R.M. Neer, J.M. Anderson, J.T. Santini Jr., M.J. Cima, and R. Langer First-in-human testing of a wirelessly controlled drug delivery microchip Sci. Transl. Med. 4 2012
60. M.T. Salam, M. Mirzaei, M.S. Ly, N. Dang Khoa, and M. Sawan An implantable closedloop asynchronous drug delivery system for the treatment of refractory epilepsy IEEE Trans. Neural Syst. Rehabil. Eng. 20 2012 432 442
61. V. Ravaine, C. Ancla, and B. Catargi Chemically controlled closed-loop insulin delivery J. Control. Release 132 2008 2 11
62. S.K. Peasah, E. Azziz-Baumgartner, J. Breese, M.I. Meltzer, and M.-A. Widdowson Influenza cost and cost-effectiveness studies globally - a review Vaccine 31 2013 5339 5348
63. T.P. Monath Vaccines against diseases transmitted from animals to humans: a one health paradigm Vaccine 31 2013 5321 5338
64. M.R. Prausnitz, and R. Langer Transdermal drug delivery Nat. Biotechnol. 26 2008 1261 1268
65. J.W. Lee, J.H. Park, and M.R. Prausnitz Dissolving microneedles for transdermal drug delivery Biomaterials 29 2008 2113 2124
66. S. Henry, D.V. McAllister, M.G. Allen, and M.R. Prausnitz Microfabricated microneedles: a novel approach to transdermal drug delivery J. Pharm. Sci. 87 1998 922 925 (Pubitemid 28381247)
67. S.P. Sullivan, D.G. Koutsonanos, M.D. Martin, J.W. Lee, V. Zarnitsyn, S.O. Choi, N. Murthy, R.W. Compans, I. Skountzou, and M.R. Prausnitz Dissolving polymer microneedle patches for influenza vaccination Nat. Med. 16 2010 915 920
68. L.Y. Chu, and M.R. Prausnitz Separable arrowhead microneedles J. Control. Release 149 2011 242 249
69. M.C. Chen, S.F. Huang, K.Y. Lai, and M.H. Ling Fully embeddable chitosan microneedles as a sustained release depot for intradermal vaccination Biomaterials 34 2013 3077 3086
70. P.C. DeMuth, A.V. Li, P. Abbink, J. Liu, H. Li, K.A. Stanley, K.M. Smith, C.L. Lavine, M.S. Seaman, J.A. Kramer, A.D. Miller, W. Abraham, H. Suh, J. Elkhader, P.T. Hammond, D.H. Barouch, and D.J. Irvine Nat. Biotechnol. 31 2013 1082 1085
71. W.E. Katstra, R.D. Palazzolo, C.W. Rowe, B. Giritlioglu, P. Teung, and M.J. Cima Oral dosage forms fabricated by three dimensional printing™ J. Control. Release 66 2000 1 9 (Pubitemid 30116679)
72. N. Scoutaris, M.R. Alexander, P.R. Gellert, and C.J. Roberts Inkjet printing as a novel medicine formulation technique J. Control. Release 156 2011 179 185
73. L.G. Bermúdez-Humarán, C. Aubry, J.P. Motta, C. Deraison, L. Steidler, N. Vergnolle, J.M. Chatel, and P. Langella Engineering lactococci and lactobacilli for human health Curr. Opin. Microbiol. 16 2013 278 283
74. K. Chung, J. Wallace, S.Y. Kim, S. Kalyanasundaram, A.S. Andalman, T.J. Davidson, J.J. Mirzabekov, K.A. Zalocusky, J. Mattis, A.K. Denisin, S. Pak, H. Bernstein, C. Ramakrishnan, L. Grosenick, V. Gradinaru, and K. Deisseroth Structural and molecular interrogation of intact biological systems Nature 497 2013 332 337
75. G. Miesenböck The optogenetic catechism Science 326 2009 395 399
76. L. Xie, H. Kang, Q. Xu, M.J. Chen, Y. Liao, M. Thiyagarajan, J. O'Donnell, D.J. Christensen, C. Nicholson, J.J. Iliff, T. Takano, R. Deane, and M. Nedergaard Sleep drives metabolite clearance from the adult brain Science 2013 373 377