Degradation and biocompatibility of multistage nanovectors in physiological systems

Journal of Biomedical Materials Research - Part A

Volumn 102, Issue 10, 2014, Pages 3540-3549

  Martinez, Jonathan O ^a,b   Evangelopoulos, Michael ^a   Chiappini, Ciro ^a,c,d   Liu, Xuewu ^a   Ferrari, Mauro ^a   Tasciotti, Ennio ^a  

^a HOUSTON METHODIST RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF TEXAS   (United States)

^c The University of Texas at Austin   (United States)

^d IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

cytocompatibility; degradation; drug delivery; multistage nanovectors; porous silicon

Indexed keywords

BIOCOMPATIBILITY; DEGRADATION; ENDOTHELIAL CELLS; NUCLEATION; POROSITY; POROUS SILICON;

ACCELERATED DEGRADATION; CELLULAR INTERNALIZATION; CYTOCOMPATIBILITY; DEGRADATION BY-PRODUCTS; DEGRADATION KINETICS; NANOVECTORS; PHYSIOLOGICAL SYSTEMS; PRE-CLINICAL TESTING;

DRUG DELIVERY;

MULTISTAGE NANOVECTOR; NANOMATERIAL; UNCLASSIFIED DRUG; BIOMATERIAL; BUFFER; DRUG CARRIER; NANOPARTICLE;

ARTICLE; ATOMIC EMISSION SPECTROMETRY; BIOCOMPATIBILITY; BIODEGRADABILITY; CELL CYCLE; CELL CYCLE PROGRESSION; CELL PROLIFERATION; CELL STRUCTURE; CYTOARCHITECTURE; DEGRADATION KINETICS; DRUG DELIVERY SYSTEM; ENDOTHELIUM CELL; FLOW CYTOMETRY; HUMAN; HUMAN CELL; INTERNALIZATION; PARTICLE SIZE; PH; POROSITY; SCANNING ELECTRON MICROSCOPY; UMBILICAL VEIN ENDOTHELIAL CELL; ZETA POTENTIAL; CHEMISTRY; CYTOLOGY; ENDOCYTOSIS; ULTRASTRUCTURE;

BIOCOMPATIBLE MATERIALS; BUFFERS; DRUG CARRIERS; ENDOCYTOSIS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; HYDROGEN-ION CONCENTRATION; NANOPARTICLES; POROSITY;

EID: 84906782364     PISSN: 15493296     EISSN: 15524965     Source Type: Journal    
DOI: 10.1002/jbm.a.35017     Document Type: Article

References (29)

1. Canham LT,. Bioactive silicon structure fabrication through nanoetching techniques. Adv Mater 1995; 7: 1033-1037.
2. Bayliss SC, Heald R, Fletcher DI, Buckberry LD,. The culture of mammalian cells on nanostructured silicon. Adv Mater 1999; 11: 318-321.
3. Pavesi L, Ceschini M, Rossi F,. Photoluminescence of porous silicon. J Lumin 1993; 57: 131-135.
4. Pavlikov AV, Lartsev AV, Gayduchenko IA, Yu Timoshenko V,. Optical properties of materials based on oxidized porous silicon and their applications for UV protection. Microelectron Eng 2012; 90: 96-98.
5. Ko PJ, Ishikawa R, Takamura T, Morimoto Y, Cho B, Sohn H, Sandhu A,. Porous-silicon photonic-crystal platform for the rapid detection of nano-sized superparamagnetic beads for biosensing applications. Nanosci Nanotechnol Lett 2011; 3: 612-616.
6. Bogaerts W, De Heyn P, Van Vaerenbergh T, De Vos K, Kumar Selvaraja S, Claes T, Dumon P, Bienstman P, Van Thourhout D, Baets R,. Silicon microring resonators. Laser Photonics Rev 2012; 6: 47-73.
7. Sun W, Puzas JE, Sheu T-J, Fauchet PM,. Porous silicon as a cell interface for bone tissue engineering. Phys Status Solidi A 2007; 204: 1429-1433.
8. Coffer JL, Whitehead MA, Nagesha DK, Mukherjee P, Akkaraju G, Totolici M, Saffie RS, Canham LT,. Porous silicon-based scaffolds for tissue engineering and other biomedical applications. Phys Status Solidi A 2005; 202: 1451-1455.
9. Wu EC, Park J-H, Park J, Segal E, Cunin Fdr, Sailor MJ,. Oxidation-triggered release of fluorescent molecules or drugs from mesoporous Si microparticles. ACS Nano 2008; 2: 2401-2409.
10. Salonen J, Laitinen L, Kaukonen AM, Tuura J, Björkqvist M, Heikkilä T, Vähä-Heikkilä K, Hirvonen J, Lehto VP,. Mesoporous silicon microparticles for oral drug delivery: Loading and release of five model drugs. J Controlled Release 2005; 108: 362-374.
11. Parodi A, Quattrocchi N, van de Ven AL, Chiappini C, Evangelopoulos M, Martinez JO, Brown BS, Khaled SZ, Yazdi IK, Enzo MV, Isenhart L, Ferrari M, Tasciotti E,. Synthetic nanoparticles functionalized with biomimetic leukocyte membranes possess cell-like functions. Nat Nanotechnol 2013; 8: 61-68.
12. Prestidge CA, Barnes TJ, Lau CH, Barnett C, Loni A, Canham L,. Mesoporous silicon: A platform for the delivery of therapeutics. Expert Opin Drug Deliv 2007; 4: 101-110.
13. Low SP, Voelcker NH, Canham LT, Williams KA,. The biocompatibility of porous silicon in tissues of the eye. Biomaterials 2009; 30: 2873-2880.
14. Jurkic LM, Cepanec I, Pavelic SK, Pavelic K,. Biological and therapeutic effects of ortho-silicic acid and some ortho-silicic acid-releasing compounds: New perspectives for therapy. Nutr Metab (Lond) 2013; 10: 2.
15. Jugdaohsingh R, Reffitt DM, Oldham C, Day JP, Fifield LK, Thompson RP, Powell JJ,. Oligomeric but not monomeric silica prevents aluminum absorption in humans. Am J Clin Nutr 2000; 71: 944-949.
16. Kawahara M, Kato-Negishi M,. Link between aluminum and the pathogenesis of Alzheimer's disease: The integration of the aluminum and amyloid cascade hypotheses. Int J Alzheimers Dis 2011; 2011: 276393.
17. Reffitt DM, Ogston N, Jugdaohsingh R, Cheung HF, Evans BA, Thompson RP, Powell JJ, Hampson GN,. Orthosilicic acid stimulates collagen type 1 synthesis and osteoblastic differentiation in human osteoblast-like cells in vitro. Bone 2003; 32: 127-135.
18. Chiappini C, Tasciotti E, Fakhoury JR, Fine D, Pullan L, Wang YC, Fu L, Liu X, Ferrari M,. Tailored porous silicon microparticles: Fabrication and properties. Chemphyschem 2010; 11: 1029-1035.
19. Tasciotti E, Liu X, Bhavane R, Plant K, Leonard AD, Price BK, Cheng MM-C, Decuzzi P, Tour JM, Robertson F, Ferrari M,. Mesoporous silicon particles as a multistage delivery system for imaging and therapeutic applications. Nat Nano 2008; 3: 151-157.
20. Ananta JS, Godin B, Sethi R, Moriggi L, Liu X, Serda RE, Krishnamurthy R, Muthupillai R, Bolskar RD, Helm L, Ferrari M, Wilson LJ, Decuzzi P,. Geometrical confinement of gadolinium-based contrast agents in nanoporous particles enhances T1 contrast. Nat Nanotechnol 2010; 5: 815-821.
21. Tanaka T, Mangala LS, Vivas-Mejia PE, Nieves-Alicea R, Mann AP, Mora E, Han HD, Shahzad MM, Liu X, Bhavane R, Gu J, Fakhoury JR, Chiappini C, Lu C, Matsuo K, Godin B, Stone RL, Nick AM, Lopez-Berestein G, Sood AK, Ferrari M,. Sustained small interfering RNA delivery by mesoporous silicon particles. Cancer Res 2010; 70: 3687-3696.
22. Godin B, Gu J, Serda RE, Bhavane R, Tasciotti E, Chiappini C, Liu X, Tanaka T, Decuzzi P, Ferrari M,. Tailoring the degradation kinetics of mesoporous silicon structures through PEGylation. J Biomed Mater Res A 2010; 94: 1236-1243.
23. Bimbo LM, Makila E, Laaksonen T, Lehto VP, Salonen J, Hirvonen J, Santos HA,. Drug permeation across intestinal epithelial cells using porous silicon nanoparticles. Biomaterials 2011; 32: 2625-2633.
24. Martinez JO, Chiappini C, Ziemys A, Faust AM, Kojic M, Liu X, Ferrari M, Tasciotti E,. Engineering multi-stage nanovectors for controlled degradation and tunable release kinetics. Biomaterials 2013; 34: 8469-8477.
25. Martinez JO, Boada C, Yazdi IK, Evangelopoulos M, Brown BS, Liu X, Ferrari M, Tasciotti E,. Short and long term, in vitro and in vivo correlations of cellular and tissue responses to mesoporous silicon nanovectors. Small 2013; 9: 1722-1733.
26. Genzel Y, Konig S, Reichl U,. Amino acid analysis in mammalian cell culture media containing serum and high glucose concentrations by anion exchange chromatography and integrated pulsed amperometric detection. Anal Biochem 2004; 335: 119-125.
27. Sailor MJ,. Fundamentals of Porous Silicon Preparation. Porous Silicon in Practice. Germany: Wiley-VCH Verlag GmbH & Co. KGaA; 2011. p 1-42.
28. Carlisle EM,. Silicon: An essential element for the chick. Science 1972; 178: 619-621.
29. Martinez JO, Parodi A, Liu X, Kolonin MG, Ferrari M, Tasciotti E,. Evaluation of cell function upon nanovector internalization. Small 2013; 9: 1696-1702.