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Volumn 8, Issue 10, 2013, Pages
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A high-content small molecule screen identifies sensitivity of glioblastoma stem cells to inhibition of polo-like kinase 1.
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Author keywords
[No Author keywords available]
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Indexed keywords
(6,7 DIMETHOXY 2,4 DIHYDROINDENO(1,2 C)PYRAZOL 3 YL)(3 FLUOROPHENYL)AMINE;
(6,7-DIMETHOXY-2,4-DIHYDROINDENO(1,2-C)PYRAZOL-3-YL)(3-FLUOROPHENYL)AMINE;
4 (8 CYCLOPENTYL 7 ETHYL 5,6,7,8 TETRAHYDRO 5 METHYL 6 OXO 2 PTERIDINYLAMINO) 3 METHOXY N (1 METHYL 4 PIPERIDINYL)BENZAMIDE;
BENZIMIDAZOLE DERIVATIVE;
CELL CYCLE PROTEIN;
GSK 461364;
INDAN DERIVATIVE;
ONCOPROTEIN;
POLO LIKE KINASE 1;
POLO-LIKE KINASE 1;
PROTEIN KINASE INHIBITOR;
PROTEIN P53;
PROTEIN SERINE THREONINE KINASE;
PTERIDINE DERIVATIVE;
PYRAZOLE DERIVATIVE;
THIOPHENE DERIVATIVE;
VOLASERTIB;
ANIMAL;
ARTICLE;
BLOOD BRAIN BARRIER;
BRAIN TUMOR;
CANCER STEM CELL;
CELL CULTURE;
CELL CYCLE CHECKPOINT;
CELL SURVIVAL;
DRUG ANTAGONISM;
DRUG EFFECT;
DRUG SCREENING;
ENZYMOLOGY;
GENETICS;
GLIOBLASTOMA;
HUMAN;
KNOCKOUT MOUSE;
METABOLISM;
METHODOLOGY;
MOLECULAR LIBRARY;
MOUSE;
NEURAL STEM CELL;
PATHOLOGY;
REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;
SWINE;
TUMOR CELL LINE;
WESTERN BLOTTING;
ANIMALS;
BENZIMIDAZOLES;
BLOOD-BRAIN BARRIER;
BLOTTING, WESTERN;
BRAIN NEOPLASMS;
CELL CYCLE CHECKPOINTS;
CELL CYCLE PROTEINS;
CELL LINE, TUMOR;
CELL SURVIVAL;
CELLS, CULTURED;
DRUG SCREENING ASSAYS, ANTITUMOR;
GLIOBLASTOMA;
HUMANS;
INDANS;
MICE;
MICE, KNOCKOUT;
NEOPLASTIC STEM CELLS;
NEURAL STEM CELLS;
PROTEIN KINASE INHIBITORS;
PROTEIN-SERINE-THREONINE KINASES;
PROTO-ONCOGENE PROTEINS;
PTERIDINES;
PYRAZOLES;
REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;
SMALL MOLECULE LIBRARIES;
SWINE;
THIOPHENES;
TUMOR SUPPRESSOR PROTEIN P53;
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EID: 84906526438
PISSN: None
EISSN: 19326203
Source Type: Journal
DOI: 10.1371/journal.pone.0077053 Document Type: Article |
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Times cited : (52)
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References (0)
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