Time to declare a moratorium on stress ulcer prophylaxis in critically Ill

Critical Care Medicine

Volumn 42, Issue 9, 2014, Pages

  Alaniz, Cesar ^a   Hyzy, Robert C ^a  

^a UNIVERSITY OF MICHIGAN HOSPITALS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HISTAMINE H2 RECEPTOR ANTAGONIST; PLACEBO; PROTON PUMP INHIBITOR;

CLOSTRIDIUM DIFFICILE INFECTION; COST EFFECTIVENESS ANALYSIS; CRITICALLY ILL PATIENT; ENTERIC FEEDING; GASTROINTESTINAL HEMORRHAGE; HOSPITAL ACQUIRED PNEUMONIA; HUMAN; INTENSIVE CARE; INTENSIVE CARE UNIT; LETTER; MORTALITY; PRIORITY JOURNAL; PROPHYLAXIS; RISK FACTOR; STRESS ULCER;

CRITICAL ILLNESS; HISTAMINE H2 ANTAGONISTS; HUMANS; INTENSIVE CARE UNITS; PEPTIC ULCER; PROTON PUMPS; STRESS, PHYSIOLOGICAL;

EID: 84906345933     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0000000000000471     Document Type: Letter

References (5)

1. MacLaren R, Campbell J: Cost-Effectiveness of Histamine Receptor-2 Antagonist Versus Proton Pump Inhibitor for Stress Ulcer Prophylaxis in Critically Ill Patients. Crit Care Med 2014; 42:809-815
2. Krag M, Perner A, Wetterslev J, et al: Stress ulcer prophylaxis versus placebo or no prophylaxis in critically ill patients. A systematic review of randomised clinical trials with meta-analysis and trial sequential analysis. Intensive Care Med 2014; 40:11-22
3. Marik PE, Vasu T, Hirani A, et al: Stress ulcer prophylaxis in the new millennium: A systematic review and meta-analysis. Crit Care Med 2010; 38:2222-2228
4. Alaniz C, Hyzy RC: Albumin meta-analysis and epochs of care. Crit Care Med 2011; 39:1852
5. Buendgens L, Bruensing J, Matthes M, et al: Administration of proton pump inhibitors in critically ill medical patients is associated with increased risk of developing Clostridium difficile-associated diarrhea. J Crit Care 2014; 29: 696.e11-696.e15