The large GTPase Mx1 is involved in apical transport in MDCK cells

Traffic

Volumn 15, Issue 9, 2014, Pages 983-996

  Hoff, Florian ^a   Greb, Christoph ^a   Hollmann, Christina ^a   Hönig, Ellena ^a   Jacob, Ralf ^a  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

Author keywords

Apical trafficking; MDCK cells; Mx proteins; Polarized epithelia; Transport vesicle

Indexed keywords

DYNAMIN; GREEN FLUORESCENT PROTEIN; GUANOSINE TRIPHOSPHATASE; GUANOSINE TRIPHOSPHATASE MX1; MOLECULAR MOTOR; NEUROTROPHIN RECEPTOR P75; RAB PROTEIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; CARRIER PROTEIN; NERVE GROWTH FACTOR RECEPTOR;

ANIMAL CELL; APICAL MEMBRANE; APICAL TRAFFICKING; ARTICLE; CELL MEMBRANE; CELL TRANSPORT; EPITHELIUM CELL; FLUORESCENCE MICROSCOPY; MDCK CELL LINE; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN PURIFICATION; PROTEIN TRANSPORT; ANIMAL; CELL LINE; DOG; GOLGI COMPLEX; METABOLISM; PHYSIOLOGY; PROCEDURES;

ANIMALS; CARRIER PROTEINS; CELL LINE; CELL MEMBRANE; DOGS; EPITHELIAL CELLS; GOLGI APPARATUS; GTP PHOSPHOHYDROLASES; MADIN DARBY CANINE KIDNEY CELLS; MICROSCOPY, FLUORESCENCE; PROTEIN TRANSPORT; RECEPTOR, NERVE GROWTH FACTOR;

EID: 84906311450     PISSN: 13989219     EISSN: 16000854     Source Type: Journal    
DOI: 10.1111/tra.12186     Document Type: Article

References (30)

1. Apodaca G, Gallo LI, Bryant DM. Role of membrane traffic in the generation of epithelial cell asymmetry. Nat Cell Biol 2012;14:1235-1243.
2. Rodriguez-Boulan E, Kreitzer G, Musch A. Organization of vesicular trafficking in epithelia. Nat Rev Mol Cell Biol 2005;6:233-247.
3. Breuza L, Garcia M, Delgrossi MH, Le Bivic A. Role of the membrane-proximal O-glycosylation site in sorting of the human receptor for neurotrophins to the apical membrane of MDCK cells. Exp Cell Res 2002;273:178-186.
4. Yeaman C, Le Gall AH, Baldwin AN, Monlauzeur L, Le Bivic A, Rodriguez-Boulan E. The O-glycosylated stalk domain is required for apical sorting of neurotrophin receptors in polarized MDCK cells. J Cell Biol 1997;139:929-940.
5. Delacour D, Greb C, Koch A, Salomonsson E, Leffler H, Le Bivic A, Jacob R. Apical sorting by galectin-3-dependent glycoprotein clustering. Traffic 2007;8:379-388.
6. Kreitzer G, Marmorstein A, Okamoto P, Vallee R, Rodriguez-Boulan E. Kinesin and dynamin are required for post-Golgi transport of a plasma-membrane protein. Nat Cell Biol 2000;2:125-127.
7. Salvarezza SB, Deborde S, Schreiner R, Campagne F, Kessels MM, Qualmann B, Caceres A, Kreitzer G, Rodriguez-Boulan E. LIM kinase 1 and cofilin regulate actin filament population required for dynamin-dependent apical carrier fission from the trans-Golgi network. Mol Biol Cell 2009;20:438-451.
8. Astanina K, Jacob R. KIF5C, a kinesin motor involved in apical trafficking of MDCK cells. Cell Mol Life Sci 2010;67:1331-1342.
9. Jaulin F, Xue X, Rodriguez-Boulan E, Kreitzer G. Polarization-dependent selective transport to the apical membrane by KIF5B in MDCK cells. Dev Cell 2007;13:511-522.
10. Ang AL, Folsch H, Koivisto UM, Pypaert M, Mellman I. The Rab8 GTPase selectively regulates AP-1B-dependent basolateral transport in polarized Madin-Darby canine kidney cells. J Cell Biol 2003;163:339-350.
11. Cramm-Behrens CI, Dienst M, Jacob R. Apical cargo traverses endosomal compartments on the passage to the cell surface. Traffic 2008;9:2206-2220.
12. Cresawn KO, Potter BA, Oztan A, Guerriero CJ, Ihrke G, Goldenring JR, Apodaca G, Weisz OA. Differential involvement of endocytic compartments in the biosynthetic traffic of apical proteins. EMBO J 2007;26:3737-3748.
13. Haller O, Staeheli P, Kochs G. Interferon-induced Mx proteins in antiviral host defense. Biochimie 2007;89:812-818.
14. Seitz C, Frensing T, Hoper D, Kochs G, Reichl U. High yields of influenza A virus in Madin-Darby canine kidney cells are promoted by an insufficient interferon-induced antiviral state. J Gen Virol 2010;91(Pt 7):1754-1763.
15. Chi RJ, Liu J, West M, Wang J, Odorizzi G, Burd CG. Fission of SNX-BAR-coated endosomal retrograde transport carriers is promoted by the dynamin-related protein Vps1. J Cell Biol 2014;204:793-806.
16. Rothman JH, Raymond CK, Gilbert T, O'Hara PJ, Stevens TH. A putative GTP binding protein homologous to interferon-inducible Mx proteins performs an essential function in yeast protein sorting. Cell 1990;61:1063-1074.
17. Jatiani SS, Mittal R. Expression of the antiviral protein MxA in cells transiently perturbs endocytosis. Biochem Biophys Res Commun 2004;323:541-546.
18. Palm M, Garigliany MM, Cornet F, Desmecht D. Interferon-induced Sus scrofa Mx1 blocks endocytic traffic of incoming influenza A virus particles. Vet Res 2010;41:29.
19. Toyokawa K, Carling SJ, Ott TL. Cellular localization and function of the antiviral protein, ovine Mx1 (oMx1): I. Ovine Mx1 is secreted by endometrial epithelial cells via an 'unconventional' secretory pathway. Am J Reprod Immunol 2007;57:13-22.
20. Stertz S, Reichelt M, Krijnse-Locker J, Mackenzie J, Simpson JC, Haller O, Kochs G. Interferon-induced, antiviral human MxA protein localizes to a distinct subcompartment of the smooth endoplasmic reticulum. J Interferon Cytokine Res 2006;26:650-660.
21. Straube T, von Mach T, Honig E, Greb C, Schneider D, Jacob R. PH-dependent recycling of galectin-3 at the apical membrane of epithelial cells. Traffic 2013;14:1014-1027.
22. Racicot K, Schmitt A, Ott T. The myxovirus-resistance protein, MX1, is a component of exosomes secreted by uterine epithelial cells. Am J Reprod Immunol 2012;67:498-505.
23. Mushinski JF, Nguyen P, Stevens LM, Khanna C, Lee S, Chung EJ, Lee MJ, Kim YS, Linehan WM, Horisberger MA, Trepel JB. Inhibition of tumor cell motility by the interferon-inducible GTPase MxA. J Biol Chem 2009;284:15206-15214.
24. Huotari J, Helenius A. Endosome maturation. EMBO J 2011;30:3481-3500.
25. Lindstedt R, Apodaca G, Barondes SH, Mostov KE, Leffler H. Apical secretion of a cytosolic protein by Madin-Darby canine kidney cells. Evidence for polarized release of an endogenous lectin by a nonclassical secretory pathway. J Biol Chem 1993;268:11750-11757.
26. Accola MA, Huang B, Al MA, McNiven MA. The antiviral dynamin family member, MxA, tubulates lipids and localizes to the smooth endoplasmic reticulum. J Biol Chem 2002;277:21829-21835.
27. Gao S, von der Malsburg A, Paeschke S, Behlke J, Haller O, Kochs G, Daumke O. Structural basis of oligomerization in the stalk region of dynamin-like MxA. Nature 2010;465:502-506.
28. von der Malsburg A, Abutbul-Ionita I, Haller O, Kochs G, Danino D. Stalk domain of the dynamin-like MxA GTPase protein mediates membrane binding and liposome tubulation via the unstructured L4 loop. J Biol Chem 2011;286:37858-37865.
29. Bonekamp NA, Vormund K, Jacob R, Schrader M. Dynamin-like protein 1 at the Golgi complex: a novel component of the sorting/targeting machinery en route to the plasma membrane. Exp Cell Res 2010;316:3454-3467.
30. Fairn GD, Schieber NL, Ariotti N, Murphy S, Kuerschner L, Webb RI, Grinstein S, Parton RG. High-resolution mapping reveals topologically distinct cellular pools of phosphatidylserine. J Cell Biol 2011;194:257-275.