메뉴 건너뛰기




Volumn 111, Issue 33, 2014, Pages 11967-11972

Evolved developmental homeostasis disturbed in LB1 from Flores, Indonesia, denotes Down syndrome and not diagnostic traits of the invalid species Homo floresiensis

Author keywords

Asymmetry; Atavism; Body height; Body mass

Indexed keywords

ARTHROPATHY; ARTICLE; ATLANTOOCCIPITAL JOINT; BONE DYSPLASIA; BRACHYCEPHALY; BRAIN SIZE; CAVE; CEREBELLUM; CLINICAL STUDY; DENTAL CARIES; DOWN SYNDROME; FACE ASYMMETRY; FEMUR; GEOGRAPHIC DISTRIBUTION; HOMEOSTASIS; HOMO FLORESIENSIS; HUMAN; HYPOTHYROIDISM; INDONESIA; MICROGNATHIA; PERIODONTITIS; PLAGIOCEPHALY; PREDICTION; PRIORITY JOURNAL; SHORT STATURE; SKULL; WRIST DISEASE;

EID: 84906311187     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1407382111     Document Type: Article
Times cited : (37)

References (75)
  • 2
    • 77952756773 scopus 로고    scopus 로고
    • Homo floresiensis. What is it? Where does it fit in the human story?
    • ed Indriati E (Laboratory of Bioanthropology and Paleoanthropology, Faculty of Medicine, Gadjah Mada Univ, Yogyakarta, Indonesia)
    • Argue D, Morwood M, Sutikna T Jatmiko, and Saptomo W (2007) Homo floresiensis. What is it? Where does it fit in the human story? Recent Advances on Southeast Asian Paleoanthropology and Archaeology, ed Indriati E (Laboratory of Bioanthropology and Paleoanthropology, Faculty of Medicine, Gadjah Mada Univ, Yogyakarta, Indonesia), pp 47-53.
    • (2007) Recent Advances on Southeast Asian Paleoanthropology and Archaeology , pp. 47-53
    • Argue, D.1    Morwood, M.2    Sutikna, T.3    Jatmiko4    Saptomo, W.5
  • 4
    • 84906308313 scopus 로고
    • Forward
    • eds Müller DW, McKenzie JA, Weissert H (Academic Press, London)
    • Schlanger SO (1991) Forward. Controversies in Modern Geology, eds Müller DW, McKenzie JA, Weissert H (Academic Press, London), p xi.
    • (1991) Controversies in Modern Geology
    • Schlanger, S.O.1
  • 5
    • 84906323536 scopus 로고    scopus 로고
    • Foreword
    • eds Briegel U, Xiao W (Elsevier, Amsterdam)
    • Briegel U (2001) Foreword. Paradoxes in Geology, eds Briegel U, Xiao W (Elsevier, Amsterdam), p v.
    • (2001) Paradoxes in Geology
    • Briegel, U.1
  • 6
    • 0002239908 scopus 로고
    • The desiccated deep basinmodel for the Messinian events
    • ed Drooger CW (Kon Ned Akad Weten, Amsterdam)
    • Hsü KJ (1973) The desiccated deep basinmodel for the Messinian events. Messinian Events in the Mediterranean, ed Drooger CW (Kon Ned Akad Weten, Amsterdam), pp 60-67.
    • (1973) Messinian Events in the Mediterranean , pp. 60-67
    • Hsü, K.J.1
  • 7
    • 36949052160 scopus 로고
    • Late Miocene desiccation of the Mediterranean
    • Hsü KJ, Ryan WBF, Cita MB (1972) Late Miocene desiccation of the Mediterranean. Nature 242(5395):240-244.
    • (1972) Nature , vol.242 , Issue.5395 , pp. 240-244
    • Hsü, K.J.1    Ryan, W.B.F.2    Cita, M.B.3
  • 8
  • 9
    • 72049130334 scopus 로고    scopus 로고
    • Catastrophic flood of the Mediterranean after the Messinian salinity crisis
    • Garcia-Castellanos D, et al. (2009) Catastrophic flood of the Mediterranean after the Messinian salinity crisis. Nature 462(7274):778-781.
    • (2009) Nature , vol.462 , Issue.7274 , pp. 778-781
    • Garcia-Castellanos, D.1
  • 12
    • 33748936304 scopus 로고    scopus 로고
    • Homo floresiensis: Microcephalic, pygmoid, Australopithecus, or Homo?
    • Argue D, Donlon D, Groves C, Wright R (2006) Homo floresiensis: microcephalic, pygmoid, Australopithecus, or Homo? J Hum Evol 51(4):360-374.
    • (2006) J Hum Evol , vol.51 , Issue.4 , pp. 360-374
    • Argue, D.1    Donlon, D.2    Groves, C.3    Wright, R.4
  • 13
    • 84877657906 scopus 로고    scopus 로고
    • Outside of Africa: Our surprising origins
    • Barras C (2013) Outside of Africa: Our surprising origins. New Sci 218(2916):40-43.
    • (2013) New Sci , vol.218 , Issue.2916 , pp. 40-43
    • Barras, C.1
  • 17
    • 84869867273 scopus 로고    scopus 로고
    • Flores feet, factoids, and fairytales
    • Eckhardt RB, Henneberg M (2012) Flores feet, factoids, and fairytales. Am J Phys Anthropol 80(Suppl):137.
    • (2012) Am J Phys Anthropol , vol.80 , Issue.SUPPL. , pp. 137
    • Eckhardt, R.B.1    Henneberg, M.2
  • 19
    • 77149135049 scopus 로고    scopus 로고
    • The mode and rate of human evolution and the recent Liang Bua finds
    • ed Indriati E (Laboratory of Bioanthropology and Paleoanthropology, Faculty of Medicine, Gadjah Mada University, Yogyakarta, Indonesia)
    • Henneberg M (2007) The mode and rate of human evolution and the recent Liang Bua finds. Recent Advances of Southeast Asia Paleoanthropology and Archaeology, ed Indriati E (Laboratory of Bioanthropology and Paleoanthropology, Faculty of Medicine, Gadjah Mada University, Yogyakarta, Indonesia), pp 24-29.
    • (2007) Recent Advances of Southeast Asia Paleoanthropology and Archaeology , pp. 24-29
    • Henneberg, M.1
  • 20
    • 0003108480 scopus 로고
    • Development of a scientific controversy
    • eds Müller DW, McKenzie JA, Weissert H (Academic Press, London)
    • Cita M (1991) Development of a scientific controversy. Controversies in Modern Geology, eds Müller DW, McKenzie JA, Weissert H (Academic Press, London), pp 13-23.
    • (1991) Controversies in Modern Geology , pp. 13-23
    • Cita, M.1
  • 22
    • 80455174377 scopus 로고    scopus 로고
    • Craniofacial morphology of Homo floresiensis: Description, taxonomic affinities, and evolutionary implication
    • Kaifu Y, et al. (2011) Craniofacial morphology of Homo floresiensis: Description, taxonomic affinities, and evolutionary implication. J Hum Evol 61(6):644-682.
    • (2011) J Hum Evol , vol.61 , Issue.6 , pp. 644-682
    • Kaifu, Y.1
  • 23
    • 84879045552 scopus 로고    scopus 로고
    • Brain size of Homo floresiensis and its evolutionary implications
    • Kubo D, Kono RT, Kaifu Y (2013) Brain size of Homo floresiensis and its evolutionary implications. Proc Biol Sci 280(1760):20130338.
    • (2013) Proc Biol Sci , vol.280 , Issue.1760 , pp. 20130338
    • Kubo, D.1    Kono, R.T.2    Kaifu, Y.3
  • 24
    • 68949122633 scopus 로고    scopus 로고
    • The type specimen (LB1) of Homo floresiensis did not have Laron syndrome
    • Falk D, et al. (2009) The type specimen (LB1) of Homo floresiensis did not have Laron syndrome. Am J Phys Anthropol 140(1):52-63.
    • (2009) Am J Phys Anthropol , vol.140 , Issue.1 , pp. 52-63
    • Falk, D.1
  • 25
    • 70449107133 scopus 로고    scopus 로고
    • Size, shape, and asymmetry in fossil hominins: The status of the LB1 cranium based on 3D morphometric analyses
    • Baab KL, McNulty KP (2009) Size, shape, and asymmetry in fossil hominins: the status of the LB1 cranium based on 3D morphometric analyses. J Hum Evol 57(5):608-622.
    • (2009) J Hum Evol , vol.57 , Issue.5 , pp. 608-622
    • Baab, K.L.1    McNulty, K.P.2
  • 26
    • 68949113843 scopus 로고    scopus 로고
    • Brief communication: "Pathological" deformation in the skull of LB1, the type specimen of Homo floresiensis
    • Kaifu Y, et al. (2009) Brief communication: "Pathological" deformation in the skull of LB1, the type specimen of Homo floresiensis. Am J Phys Anthropol 140(1):177-185.
    • (2009) Am J Phys Anthropol , vol.140 , Issue.1 , pp. 177-185
    • Kaifu, Y.1
  • 27
    • 34548751187 scopus 로고    scopus 로고
    • Comparative skeletal features between Homo floresiensis and patients with primary growth hormone insensitivity (Laron Syndrome)
    • DOI 10.1002/ajpa.20655
    • Hershkovitz I, Kornreich L, Laron Z (2007) Comparative skeletal features between Homo floresiensis and patients with primary growth hormone insensitivity (Laron Syndrome). Am J Phys Anthropol 134(2):198-208. (Pubitemid 47438654)
    • (2007) American Journal of Physical Anthropology , vol.134 , Issue.2 , pp. 198-208
    • Hershkovitz, I.1    Kornreich, L.2    Laron, Z.3
  • 28
    • 33750028230 scopus 로고    scopus 로고
    • Genetic, physiologic and ecogeographic factors contributing to variation in Homo sapiens: Homo floresiensis reconsidered
    • Richards GD (2006) Genetic, physiologic and ecogeographic factors contributing to variation in Homo sapiens: Homo floresiensis reconsidered. J Evol Biol 19(6):1744-1767.
    • (2006) J Evol Biol , vol.19 , Issue.6 , pp. 1744-1767
    • Richards, G.D.1
  • 31
    • 77958563252 scopus 로고    scopus 로고
    • Post-cranial skeletons of hypothyroid cretins show a similar anatomical mosaic as Homo floresiensis
    • Oxnard C, Obendorf PJ, Kefford BJ (2010) Post-cranial skeletons of hypothyroid cretins show a similar anatomical mosaic as Homo floresiensis. PLoS ONE 5(9):e13018.
    • (2010) PLoS ONE , vol.5 , Issue.9
    • Oxnard, C.1    Obendorf, P.J.2    Kefford, B.J.3
  • 32
    • 78349248331 scopus 로고    scopus 로고
    • LB1 from Liang Bua, Flores: Craniofacial asymmetry confirmed, plagiocephaly diagnosis dubious
    • Eckhardt RB, Henneberg M (2010) LB1 from Liang Bua, Flores: Craniofacial asymmetry confirmed, plagiocephaly diagnosis dubious. Am J Phys Anthropol 143(3):331-334.
    • (2010) Am J Phys Anthropol , vol.143 , Issue.3 , pp. 331-334
    • Eckhardt, R.B.1    Henneberg, M.2
  • 34
    • 0020661091 scopus 로고
    • Down syndrome - A disruption of homeostasis
    • Shapiro BL (1983) Down syndrome - A disruption of homeostasis. Am J Med Genet 14(2):241-269.
    • (1983) Am J Med Genet , vol.14 , Issue.2 , pp. 241-269
    • Shapiro, B.L.1
  • 35
    • 67649605380 scopus 로고    scopus 로고
    • Descriptions of the upper limb skeleton of Homo floresiensis
    • Larson SG, et al. (2009) Descriptions of the upper limb skeleton of Homo floresiensis. J Hum Evol 57(5):555-570.
    • (2009) J Hum Evol , vol.57 , Issue.5 , pp. 555-570
    • Larson, S.G.1
  • 36
    • 0006504614 scopus 로고
    • Further investigation of the morphometric characters of the individual bones of the human skull
    • Pearson K, Woo TL (1935) Further investigation of the morphometric characters of the individual bones of the human skull. Biometrika 27(3-4):424-465.
    • (1935) Biometrika , vol.27 , Issue.3-4 , pp. 424-465
    • Pearson, K.1    Woo, T.L.2
  • 37
    • 0019439982 scopus 로고
    • Facial asymmetry in healthy North American Caucasians. An anthropometrical study
    • Farkas LG, Cheung G (1981) Facial asymmetry in healthy North American Caucasians. An anthropometrical study. Angle Orthod 51(1):70-77.
    • (1981) Angle Orthod , vol.51 , Issue.1 , pp. 70-77
    • Farkas, L.G.1    Cheung, G.2
  • 38
    • 0031299445 scopus 로고    scopus 로고
    • The prevalence of facial asymmetry in the dentofacial deformities population at the University of North Carolina
    • Severt JR, Proffit WR (1997) The prevalence of facial asymmetry in the dentofacial deformities population at the University of North Carolina. Int J Adult Orthodont Orthognath Surg 12(3):171-176.
    • (1997) Int J Adult Orthodont Orthognath Surg , vol.12 , Issue.3 , pp. 171-176
    • Severt, J.R.1    Proffit, W.R.2
  • 39
    • 0642376662 scopus 로고    scopus 로고
    • Craniofacial anthropometric analysis in Down's syndrome patients
    • Bagić I, Verzak Z (2003) Craniofacial anthropometric analysis in Down's syndrome patients. Coll Antropol 27(Suppl 2):23-30. (Pubitemid 38353160)
    • (2003) Collegium Antropologicum , vol.27 , Issue.SUPPL. 2 , pp. 23-30
    • Bagic, I.1    Verzak, Z.2
  • 40
    • 70449107246 scopus 로고    scopus 로고
    • Liang Bua Homo floresiensis mandibles and mandibular teeth: A contribution to the comparative morphology of a new hominin species
    • Brown P, Maeda T (2009) Liang Bua Homo floresiensis mandibles and mandibular teeth: A contribution to the comparative morphology of a new hominin species. J Hum Evol 57(5):571-596.
    • (2009) J Hum Evol , vol.57 , Issue.5 , pp. 571-596
    • Brown, P.1    Maeda, T.2
  • 42
    • 84880018778 scopus 로고    scopus 로고
    • Homo floresiensis contextualized: A geometric morphometric comparative analysis of fossil and pathological human samples
    • Baab KL, McNulty KP, Harvati K (2013) Homo floresiensis contextualized: A geometric morphometric comparative analysis of fossil and pathological human samples. PLoS ONE 8(7):e69119.
    • (2013) PLoS ONE , vol.8 , Issue.7
    • Baab, K.L.1    McNulty, K.P.2    Harvati, K.3
  • 43
    • 84906319872 scopus 로고    scopus 로고
    • Microcephaly: A clinical genetics approach
    • Available at Accessed April 11, 2014
    • Firth HV (2014) Microcephaly: A clinical genetics approach. UpToDate. Available at www.uptodate.com/contents/microcephaly-a-clinical-genetics- approach. Accessed April 11, 2014.
    • (2014) UpToDate
    • Firth, H.V.1
  • 45
    • 0037433652 scopus 로고    scopus 로고
    • Down's syndrome
    • DOI 10.1016/S0140-6736(03)12987-X
    • Roizen NJ, Patterson D (2003) Down's syndrome. Lancet 361(9365):1281-1289. (Pubitemid 36428586)
    • (2003) Lancet , vol.361 , Issue.9365 , pp. 1281-1289
    • Roizen, N.J.1    Patterson, D.2
  • 47
    • 0036097525 scopus 로고    scopus 로고
    • Variation in soft-tissue thicknesses on the human face and their relation to craniometric dimensions
    • DOI 10.1002/ajpa.10073
    • Simpson E, Henneberg M (2002) Variation in soft-tissue thicknesses on the human face and their relation to craniometric dimensions. Am J Phys Anthropol 118(2):121-133. (Pubitemid 34521284)
    • (2002) American Journal of Physical Anthropology , vol.118 , Issue.2 , pp. 121-133
    • Simpson, E.1    Henneberg, M.2
  • 49
    • 84872024423 scopus 로고    scopus 로고
    • The DYRK1A gene is a cause of syndromic intellectual disability with severe microcephaly and epilepsy
    • Courcet J-B, et al. (2012) The DYRK1A gene is a cause of syndromic intellectual disability with severe microcephaly and epilepsy. J Med Genet 49(12):731-736.
    • (2012) J Med Genet , vol.49 , Issue.12 , pp. 731-736
    • Courcet, J.-B.1
  • 50
    • 0025668992 scopus 로고
    • Down syndrome children often have brain with maturation delay, retardation of growth, and cortical dysgenesis
    • Wisniewski KE (1990) Down syndrome children often have brain with maturation delay, retardation of growth, and cortical dysgenesis. Am J Med Genet Suppl 7:274-281.
    • (1990) Am J Med Genet Suppl , vol.7 , pp. 274-281
    • Wisniewski, K.E.1
  • 51
    • 65549118172 scopus 로고    scopus 로고
    • The foot of Homo floresiensis
    • Jungers WL, et al. (2009) The foot of Homo floresiensis. Nature 459(7243):81-84.
    • (2009) Nature , vol.459 , Issue.7243 , pp. 81-84
    • Jungers, W.L.1
  • 53
    • 77957753372 scopus 로고    scopus 로고
    • Anthropometry of the Singaporean and Indonesian populations
    • Chuan TK, Hartono M, Kumar N (2010) Anthropometry of the Singaporean and Indonesian populations. Int J Ind Ergon 40(6):757-766.
    • (2010) Int J Ind Ergon , vol.40 , Issue.6 , pp. 757-766
    • Chuan, T.K.1    Hartono, M.2    Kumar, N.3
  • 55
    • 71749094700 scopus 로고    scopus 로고
    • In searching for constant body ratio benchmarks
    • Wang EM, Chao WC (2010) In searching for constant body ratio benchmarks. Int J Ind Ergon 40(1):59-67.
    • (2010) Int J Ind Ergon , vol.40 , Issue.1 , pp. 59-67
    • Wang, E.M.1    Chao, W.C.2
  • 56
    • 0031091966 scopus 로고    scopus 로고
    • Relative foot size and shape to general body size in Javanese, Filipinas and Japanese with special reference to habitual footwear types
    • Ashizawa K, Kumakura C, Kusomoto A, Narasaki S (1997) Relative foot size and shape to general body size in Javanese, Filipinas and Japanese with special reference to habitual footwear types. Ann Hum Biol 24(2):117-129. (Pubitemid 127467418)
    • (1997) Annals of Human Biology , vol.24 , Issue.2 , pp. 117-129
    • Ashizawa, K.1    Kumakura, C.2    Kusumoto, A.3    Narasaki, S.4
  • 57
    • 77049240680 scopus 로고
    • The length of the body and long bones of the Javanese
    • Bergman RAM, Hoo TT (1955) The length of the body and long bones of the Javanese. Doc Med Geogr Trop 7(3):197-214.
    • (1955) Doc Med Geogr Trop , vol.7 , Issue.3 , pp. 197-214
    • Bergman, R.A.M.1    Hoo, T.T.2
  • 58
    • 0019345955 scopus 로고
    • An anthropometric study of body size in Down syndrome
    • Jaswal S, Jaswal IJ (1981) An anthropometric study of body size in Down syndrome. Indian J Pediatr 48(390):81-84.
    • (1981) Indian J Pediatr , vol.48 , Issue.390 , pp. 81-84
    • Jaswal, S.1    Jaswal, I.J.2
  • 59
    • 54049146703 scopus 로고    scopus 로고
    • Early onset of stabilizing strategies for gait and obstacles: Older adults with Down syndrome
    • Smith BA, Ulrich BD (2008) Early onset of stabilizing strategies for gait and obstacles: Older adults with Down syndrome. Gait Posture 28(3):448-455.
    • (2008) Gait Posture , vol.28 , Issue.3 , pp. 448-455
    • Smith, B.A.1    Ulrich, B.D.2
  • 61
    • 10844222529 scopus 로고    scopus 로고
    • Anthropology. The astonishing micropygmies
    • Diamond J (2004) Anthropology. The astonishing micropygmies. Science 306(5704):2047-2048.
    • (2004) Science , vol.306 , Issue.5704 , pp. 2047-2048
    • Diamond, J.1
  • 63
    • 0001802861 scopus 로고
    • A re-evaluation of estimation of stature based on measurements of stature taken during life and of long bones after death
    • Trotter M, Gleser GC (1958) A re-evaluation of estimation of stature based on measurements of stature taken during life and of long bones after death. Am J Phys Anthropol 16(1):79-123.
    • (1958) Am J Phys Anthropol , vol.16 , Issue.1 , pp. 79-123
    • Trotter, M.1    Gleser, G.C.2
  • 64
    • 84906317193 scopus 로고    scopus 로고
    • Pathology of LB1 (Flores, Indonesia): Down syndrome considered
    • Eckhardt RB, Chavanaves S, Henneberg M (2013) Pathology of LB1 (Flores, Indonesia): Down syndrome considered. Am J Phys Anthropol 150:117.
    • (2013) Am J Phys Anthropol , vol.150 , pp. 117
    • Eckhardt, R.B.1    Chavanaves, S.2    Henneberg, M.3
  • 65
    • 84856511761 scopus 로고    scopus 로고
    • LB1 and LB6 Homo floresiensis are not modern human (Homo sapiens) cretins
    • Brown P (2012) LB1 and LB6 Homo floresiensis are not modern human (Homo sapiens) cretins. J Hum Evol 62(2):201-224.
    • (2012) J Hum Evol , vol.62 , Issue.2 , pp. 201-224
    • Brown, P.1
  • 66
    • 0019274379 scopus 로고
    • Taurodontism, an isolated trait associated with syndromes and X-chromosomal aneuploidy
    • Jaspers MT, Witkop CJ, Jr (1980) Taurodontism, an isolated trait associated with syndromes and X-chromosomal aneuploidy. Am J Hum Genet 32(3):396-413. (Pubitemid 11105565)
    • (1980) American Journal of Human Genetics , vol.32 , Issue.3 , pp. 396-413
    • Jaspers, M.T.1    Witkop Jr., C.J.2
  • 68
    • 79953328063 scopus 로고    scopus 로고
    • Metric dimensions of the proximal phalanges of the human hand and their relationship to side, position, and asymmetry
    • Garrido Varas CE, Thompson TJU (2011) Metric dimensions of the proximal phalanges of the human hand and their relationship to side, position, and asymmetry. J Compar Human Biol 62(2):126-143.
    • (2011) J Compar Human Biol , vol.62 , Issue.2 , pp. 126-143
    • Garrido Varas, C.E.1    Thompson, T.J.U.2
  • 69
    • 0016820286 scopus 로고
    • Down syndrome and thyroid function in adults
    • Baxter RG, et al. (1975) Down syndrome and thyroid function in adults. Lancet 2(7939):794-796.
    • (1975) Lancet , vol.2 , Issue.7939 , pp. 794-796
    • Baxter, R.G.1
  • 71
    • 0033170702 scopus 로고    scopus 로고
    • Down syndrome and thyroid disorders: A review
    • Prasher VP (1999) Down syndrome and thyroid disorders: A review. Downs Syndr Res Pract 6(1):25-42.
    • (1999) Downs Syndr Res Pract , vol.6 , Issue.1 , pp. 25-42
    • Prasher, V.P.1
  • 73
    • 84906316979 scopus 로고    scopus 로고
    • New wrist bones from Homo floresiensis
    • Orr CM, et al. (2011) New wrist bones from Homo floresiensis. Am J Phys Anthropol Suppl 144(S52):230-231.
    • (2011) Am J Phys Anthropol Suppl , vol.144 , Issue.S52 , pp. 230-231
    • Orr, C.M.1
  • 74
    • 80052185712 scopus 로고    scopus 로고
    • Craniometric ratios of microcephaly and LB1, Homo floresiensis, using MRI and endocasts
    • Vannucci RC, Barron TF, Holloway RL (2011) Craniometric ratios of microcephaly and LB1, Homo floresiensis, using MRI and endocasts. Proc Natl Acad Sci USA 108(34): 14043-14048.
    • (2011) Proc Natl Acad Sci USA , vol.108 , Issue.34 , pp. 14043-14048
    • Vannucci, R.C.1    Barron, T.F.2    Holloway, R.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.