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Volumn 95, Issue PART 9, 2014, Pages 1900-1910

Hepatitis C virus infection mediates cholesteryl ester synthesis to facilitate infectious particle production

Author keywords

[No Author keywords available]

Indexed keywords

ACAT1 ENZYME; ACAT2 ENZYME; CALRETICULIN; CHOLESTEROL; CHOLESTEROL ACYLTRANSFERASE INHIBITOR; CHOLESTEROL ESTER; ENZYME; FAT DROPLET; FILIPIN; MESSENGER RNA; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; VIRUS RNA;

EID: 84906256916     PISSN: 00221317     EISSN: 14652099     Source Type: Journal    
DOI: 10.1099/vir.0.065300-0     Document Type: Article
Times cited : (32)

References (51)
  • 1
    • 0033607281 scopus 로고    scopus 로고
    • Hepatitis C virus and other flaviviridae viruses enter cells via low density lipoprotein receptor
    • Agnello, V., Abel, G., Elfahal, M., Knight, G. B. & Zhang, Q. X. (1999). Hepatitis C virus and other flaviviridae viruses enter cells via low density lipoprotein receptor. Proc Natl Acad Sci U S A 96, 12766-12771.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 12766-12771
    • Agnello, V.1    Abel, G.2    Elfahal, M.3    Knight, G.B.4    Zhang, Q.X.5
  • 2
    • 2942715265 scopus 로고    scopus 로고
    • Characterization of the hepatitis C virus RNA replication complex associated with lipid rafts
    • Aizaki, H., Lee, K. J., Sung, V. M., Ishiko, H. & Lai, M. M. (2004). Characterization of the hepatitis C virus RNA replication complex associated with lipid rafts. Virology 324, 450-461.
    • (2004) Virology , vol.324 , pp. 450-461
    • Aizaki, H.1    Lee, K.J.2    Sung, V.M.3    Ishiko, H.4    Lai, M.M.5
  • 3
    • 77951986878 scopus 로고    scopus 로고
    • Inhibition of acylcoenzyme A: Cholesterol acyltransferase 2 (ACAT2) prevents dietary cholesterol-associated steatosis by enhancing hepatic triglyceride mobilization
    • Alger, H. M., Brown, J. M., Sawyer, J. K., Kelley, K. L., Shah, R., Wilson, M. D., Willingham, M. C. & Rudel, L. L. (2010). Inhibition of acylcoenzyme A: cholesterol acyltransferase 2 (ACAT2) prevents dietary cholesterol-associated steatosis by enhancing hepatic triglyceride mobilization. J Biol Chem 285, 14267-14274.
    • (2010) J Biol Chem , vol.285 , pp. 14267-14274
    • Alger, H.M.1    Brown, J.M.2    Sawyer, J.K.3    Kelley, K.L.4    Shah, R.5    Wilson, M.D.6    Willingham, M.C.7    Rudel, L.L.8
  • 4
    • 0030955346 scopus 로고    scopus 로고
    • Epidemiology of hepatitis C
    • Alter, M. J. (1997). Epidemiology of hepatitis C. Hepatology 26 (Suppl. 1), 62S-65S.
    • (1997) Hepatology , vol.26 , Issue.SUPPL. 1
    • Alter, M.J.1
  • 6
    • 34547592075 scopus 로고    scopus 로고
    • Disrupting the association of hepatitis C virus core protein with lipid droplets correlates with a loss in production of infectious virus
    • Boulant, S., Targett-Adams, P. & McLauchlan, J. (2007). Disrupting the association of hepatitis C virus core protein with lipid droplets correlates with a loss in production of infectious virus. J Gen Virol 88, 2204-2213.
    • (2007) J Gen Virol , vol.88 , pp. 2204-2213
    • Boulant, S.1    Targett-Adams, P.2    McLauchlan, J.3
  • 8
    • 80055073369 scopus 로고    scopus 로고
    • Trafficking of hepatitis C virus core protein during virus particle assembly
    • Counihan, N. A., Rawlinson, S. M. & Lindenbach, B. D. (2011). Trafficking of hepatitis C virus core protein during virus particle assembly. PLoS Pathog 7, e1002302.
    • (2011) PLoS Pathog , vol.7
    • Counihan, N.A.1    Rawlinson, S.M.2    Lindenbach, B.D.3
  • 9
    • 0032146915 scopus 로고    scopus 로고
    • Host-and disease-specific factors affecting steatosis in chronic hepatitis C
    • Czaja, A. J., Carpenter, H. A., Santrach, P. J. & Moore, S. B. (1998). Host-and disease-specific factors affecting steatosis in chronic hepatitis C. J Hepatol 29, 198-206.
    • (1998) J Hepatol , vol.29 , pp. 198-206
    • Czaja, A.J.1    Carpenter, H.A.2    Santrach, P.J.3    Moore, S.B.4
  • 10
    • 0036100578 scopus 로고    scopus 로고
    • Expression of hepatitis C virus proteins induces distinct membrane alterations including a candidate viral replication complex
    • Egger, D., Wölk, B., Gosert, R., Bianchi, L., Blum, H. E., Moradpour, D. & Bienz, K. (2002). Expression of hepatitis C virus proteins induces distinct membrane alterations including a candidate viral replication complex. J Virol 76, 5974-5984.
    • (2002) J Virol , vol.76 , pp. 5974-5984
    • Egger, D.1    Wölk, B.2    Gosert, R.3    Bianchi, L.4    Blum, H.E.5    Moradpour, D.6    Bienz, K.7
  • 11
    • 72949108686 scopus 로고    scopus 로고
    • Do statins reduce hepatitis C RNA titers during routine clinical use?
    • Forde, K. A., Law, C., O'Flynn, R. & Kaplan, D. E. (2009). Do statins reduce hepatitis C RNA titers during routine clinical use? World J Gastroenterol 15, 5020-5027.
    • (2009) World J Gastroenterol , vol.15 , pp. 5020-5027
    • Forde, K.A.1    Law, C.2    O'Flynn, R.3    Kaplan, D.E.4
  • 13
    • 82755163055 scopus 로고    scopus 로고
    • Hepatitis C virus core protein decreases lipid droplet turnover: A mechanism for core-induced steatosis
    • Harris, C., Herker, E., Farese, R. V., Jr & Ott, M. (2011). Hepatitis C virus core protein decreases lipid droplet turnover: a mechanism for core-induced steatosis. J Biol Chem 286, 42615-42625.
    • (2011) J Biol Chem , vol.286 , pp. 42615-42625
    • Harris, C.1    Herker, E.2    Farese Jr., R.V.3    Ott, M.4
  • 14
    • 0033880575 scopus 로고    scopus 로고
    • Sequence motifs required for lipid droplet association and protein stability are unique to the hepatitis C virus core protein
    • Hope, R. G. & McLauchlan, J. (2000). Sequence motifs required for lipid droplet association and protein stability are unique to the hepatitis C virus core protein. J Gen Virol 81, 1913-1925.
    • (2000) J Gen Virol , vol.81 , pp. 1913-1925
    • Hope, R.G.1    McLauchlan, J.2
  • 16
    • 34250337631 scopus 로고    scopus 로고
    • Hepatitis C virus production by human hepatocytes dependent on assembly and secretion of very low-density lipoproteins
    • Huang, H., Sun, F., Owen, D. M., Li, W., Chen, Y., Gale, M., Jr & Ye, J. (2007). Hepatitis C virus production by human hepatocytes dependent on assembly and secretion of very low-density lipoproteins. Proc Natl Acad Sci U S A 104, 5848-5853.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 5848-5853
    • Huang, H.1    Sun, F.2    Owen, D.M.3    Li, W.4    Chen, Y.5    Gale Jr., M.6    Ye, J.7
  • 20
    • 0034520194 scopus 로고    scopus 로고
    • Differential expression of ACAT1 and ACAT2 among cells within liver, intestine, kidney, and adrenal of nonhuman primates
    • Lee, R. G., Willingham, M. C., Davis, M. A., Skinner, K. A. & Rudel, L. L. (2000). Differential expression of ACAT1 and ACAT2 among cells within liver, intestine, kidney, and adrenal of nonhuman primates. J Lipid Res 41, 1991-2001.
    • (2000) J Lipid Res , vol.41 , pp. 1991-2001
    • Lee, R.G.1    Willingham, M.C.2    Davis, M.A.3    Skinner, K.A.4    Rudel, L.L.5
  • 21
    • 24944558128 scopus 로고    scopus 로고
    • ACAT2 contributes cholesteryl esters to newly secreted VLDL, whereas LCAT adds cholesteryl ester to LDL in mice
    • Lee, R. G., Shah, R., Sawyer, J. K., Hamilton, R. L., Parks, J. S. & Rudel, L. L. (2005). ACAT2 contributes cholesteryl esters to newly secreted VLDL, whereas LCAT adds cholesteryl ester to LDL in mice. J Lipid Res 46, 1205-1212.
    • (2005) J Lipid Res , vol.46 , pp. 1205-1212
    • Lee, R.G.1    Shah, R.2    Sawyer, J.K.3    Hamilton, R.L.4    Parks, J.S.5    Rudel, L.L.6
  • 23
    • 62649118779 scopus 로고    scopus 로고
    • ACAT inhibition and progression of carotid atherosclerosis in patients with familial hypercholesterolemia: The CAPTIVATE randomized trial
    • Meuwese, M. C., de Groot, E., Duivenvoorden, R., Trip, M. D., Ose, L., Maritz, F. J., Basart, D. C., Kastelein, J. J., Habib, R. & other authors (2009). ACAT inhibition and progression of carotid atherosclerosis in patients with familial hypercholesterolemia: the CAPTIVATE randomized trial. JAMA 301, 1131-1139.
    • (2009) JAMA , vol.301 , pp. 1131-1139
    • Meuwese, M.C.1    de Groot, E.2    Duivenvoorden, R.3    Trip, M.D.4    Ose, L.5    Maritz, F.J.6    Basart, D.C.7    Kastelein, J.J.8    Habib, R.9
  • 24
    • 42349086670 scopus 로고    scopus 로고
    • Modification of intracellular membrane structures for virus replication
    • Miller, S. & Krijnse-Locker, J. (2008). Modification of intracellular membrane structures for virus replication. Nat Rev Microbiol 6, 363-374.
    • (2008) Nat Rev Microbiol , vol.6 , pp. 363-374
    • Miller, S.1    Krijnse-Locker, J.2
  • 25
    • 0035104157 scopus 로고    scopus 로고
    • Overexpression of SR-BI in hamsters treated with a novel ACAT inhibitor (F12511)
    • Milliat, F., Férézou, J., Delhon, A. & Lutton, C. (2001). Overexpression of SR-BI in hamsters treated with a novel ACAT inhibitor (F12511). C R Acad Sci III 324, 229-234.
    • (2001) C R Acad Sci III , vol.324 , pp. 229-234
    • Milliat, F.1    Férézou, J.2    Delhon, A.3    Lutton, C.4
  • 28
    • 77952567110 scopus 로고    scopus 로고
    • Hepatitis C virus-induced steatosis: An overview
    • Negro, F. (2010). Hepatitis C virus-induced steatosis: an overview. Dig Dis 28, 294-299.
    • (2010) Dig Dis , vol.28 , pp. 294-299
    • Negro, F.1
  • 29
    • 33144465371 scopus 로고    scopus 로고
    • Association between hepatitis C virus and very-low-density lipoprotein (VLDL)/LDL analyzed in iodixanol density gradients
    • Nielsen, S. U., Bassendine, M. F., Burt, A. D., Martin, C., Pumeechockchai, W. & Toms, G. L. (2006). Association between hepatitis C virus and very-low-density lipoprotein (VLDL)/LDL analyzed in iodixanol density gradients. J Virol 80, 2418-2428.
    • (2006) J Virol , vol.80 , pp. 2418-2428
    • Nielsen, S.U.1    Bassendine, M.F.2    Burt, A.D.3    Martin, C.4    Pumeechockchai, W.5    Toms, G.L.6
  • 31
    • 79955602758 scopus 로고    scopus 로고
    • Pyripyropene A, an acyl-coenzyme A: Cholesterol acyltransferase 2-selective inhibitor, attenuates hypercholesterolemia and atherosclerosis in murine models of hyperlipidemia
    • Ohshiro, T., Matsuda, D., Sakai, K., Degirolamo, C., Yagyu, H., Rudel, L. L., Omura, S., Ishibashi, S. & Tomoda, H. (2011). Pyripyropene A, an acyl-coenzyme A: cholesterol acyltransferase 2-selective inhibitor, attenuates hypercholesterolemia and atherosclerosis in murine models of hyperlipidemia. Arterioscler Thromb Vasc Biol 31, 1108-1115.
    • (2011) Arterioscler Thromb Vasc Biol , vol.31 , pp. 1108-1115
    • Ohshiro, T.1    Matsuda, D.2    Sakai, K.3    Degirolamo, C.4    Yagyu, H.5    Rudel, L.L.6    Omura, S.7    Ishibashi, S.8    Tomoda, H.9
  • 32
    • 84885995316 scopus 로고    scopus 로고
    • Morphological and biochemical characterization of the membranous hepatitis C virus replication compartment
    • Paul, D., Hoppe, S., Saher, G., Krijnse-Locker, J. & Bartenschlager, R. (2013). Morphological and biochemical characterization of the membranous hepatitis C virus replication compartment. J Virol 87, 10612-10627.
    • (2013) J Virol , vol.87 , pp. 10612-10627
    • Paul, D.1    Hoppe, S.2    Saher, G.3    Krijnse-Locker, J.4    Bartenschlager, R.5
  • 33
    • 18244365866 scopus 로고    scopus 로고
    • Hepatitis C virus core protein inhibits microsomal triglyceride transfer protein activity and very low density lipoprotein secretion: A model of viral-related steatosis
    • Perlemuter, G., Sabile, A., Letteron, P., Vona, G., Topilco, A., Chrétien, Y., Koike, K., Pessayre, D., Chapman, J. & other authors (2002). Hepatitis C virus core protein inhibits microsomal triglyceride transfer protein activity and very low density lipoprotein secretion: a model of viral-related steatosis. FASEB J 16, 185-194.
    • (2002) FASEB J , vol.16 , pp. 185-194
    • Perlemuter, G.1    Sabile, A.2    Letteron, P.3    Vona, G.4    Topilco, A.5    Chrétien, Y.6    Koike, K.7    Pessayre, D.8    Chapman, J.9
  • 34
    • 84882890676 scopus 로고    scopus 로고
    • PTEN protein phosphatase activity regulates hepatitis C virus secretion through modulation of cholesterol metabolism
    • Peyrou, M., Clément, S., Maier, C., Bourgoin, L., Branche, E., Conzelmann, S., Kaddai, V., Foti, M. & Negro, F. (2013). PTEN protein phosphatase activity regulates hepatitis C virus secretion through modulation of cholesterol metabolism. J Hepatol 59, 420-426.
    • (2013) J Hepatol , vol.59 , pp. 420-426
    • Peyrou, M.1    Clément, S.2    Maier, C.3    Bourgoin, L.4    Branche, E.5    Conzelmann, S.6    Kaddai, V.7    Foti, M.8    Negro, F.9
  • 35
    • 0038122773 scopus 로고    scopus 로고
    • Effect of treatment with peginterferon or interferon alfa-2b and ribavirin on steatosis in patients infected with hepatitis C
    • Poynard, T., Ratziu, V., McHutchison, J., Manns, M., Goodman, Z., Zeuzem, S., Younossi, Z. & Albrecht, J. (2003). Effect of treatment with peginterferon or interferon alfa-2b and ribavirin on steatosis in patients infected with hepatitis C. Hepatology 38, 75-85.
    • (2003) Hepatology , vol.38 , pp. 75-85
    • Poynard, T.1    Ratziu, V.2    McHutchison, J.3    Manns, M.4    Goodman, Z.5    Zeuzem, S.6    Younossi, Z.7    Albrecht, J.8
  • 36
    • 35548953149 scopus 로고    scopus 로고
    • Cholesterol regulates ACAT2 gene expression and enzyme activity in human hepatoma cells
    • Pramfalk, C., Angelin, B., Eriksson, M. & Parini, P. (2007). Cholesterol regulates ACAT2 gene expression and enzyme activity in human hepatoma cells. Biochem Biophys Res Commun 364, 402-409.
    • (2007) Biochem Biophys Res Commun , vol.364 , pp. 402-409
    • Pramfalk, C.1    Angelin, B.2    Eriksson, M.3    Parini, P.4
  • 38
    • 84856732297 scopus 로고    scopus 로고
    • Identification of the Niemann-Pick C1-like 1 cholesterol absorption receptor as a new hepatitis C virus entry factor
    • Sainz, B., Jr, Barretto, N., Martin, D. N., Hiraga, N., Imamura, M., Hussain, S., Marsh, K. A., Yu, X., Chayama, K. & other authors (2012). Identification of the Niemann-Pick C1-like 1 cholesterol absorption receptor as a new hepatitis C virus entry factor. Nat Med 18, 281-285.
    • (2012) Nat Med , vol.18 , pp. 281-285
    • Sainz Jr., B.1    Barretto, N.2    Martin, D.N.3    Hiraga, N.4    Imamura, M.5    Hussain, S.6    Marsh, K.A.7    Yu, X.8    Chayama, K.9
  • 41
    • 0035068318 scopus 로고    scopus 로고
    • Hepatitis C virus induced hypobetalipoproteinemia: A possible mechanism for steatosis in chronic hepatitis C
    • Serfaty, L., Andreani, T., Giral, P., Carbonell, N., Chazouillères, O. & Poupon, R. (2001). Hepatitis C virus induced hypobetalipoproteinemia: a possible mechanism for steatosis in chronic hepatitis C. J Hepatol 34, 428-434.
    • (2001) J Hepatol , vol.34 , pp. 428-434
    • Serfaty, L.1    Andreani, T.2    Giral, P.3    Carbonell, N.4    Chazouillères, O.5    Poupon, R.6
  • 42
    • 37549005607 scopus 로고    scopus 로고
    • The lipid droplet binding domain of hepatitis C virus core protein is a major determinant for efficient virus assembly
    • Shavinskaya, A., Boulant, S., Penin, F., McLauchlan, J. & Bartenschlager, R. (2007). The lipid droplet binding domain of hepatitis C virus core protein is a major determinant for efficient virus assembly. J Biol Chem 282, 37158-37169.
    • (2007) J Biol Chem , vol.282 , pp. 37158-37169
    • Shavinskaya, A.1    Boulant, S.2    Penin, F.3    McLauchlan, J.4    Bartenschlager, R.5
  • 44
    • 0028886611 scopus 로고
    • TMP-153, a novel ACAT inhibitor, lowers plasma cholesterol through its hepatic action in golden hamsters
    • Sugiyama, Y., Odaka, H., Itokawa, S., Ishikawa, E., Tomari, Y. & Ikeda, H. (1995). TMP-153, a novel ACAT inhibitor, lowers plasma cholesterol through its hepatic action in golden hamsters. Atherosclerosis 118, 145-153.
    • (1995) Atherosclerosis , vol.118 , pp. 145-153
    • Sugiyama, Y.1    Odaka, H.2    Itokawa, S.3    Ishikawa, E.4    Tomari, Y.5    Ikeda, H.6
  • 45
    • 0036790413 scopus 로고    scopus 로고
    • Consequences of cellular cholesterol accumulation: Basic concepts and physiological implications
    • Tabas, I. (2002). Consequences of cellular cholesterol accumulation: basic concepts and physiological implications. J Clin Invest 110, 905-911.
    • (2002) J Clin Invest , vol.110 , pp. 905-911
    • Tabas, I.1
  • 46
    • 34548181881 scopus 로고    scopus 로고
    • ACAT2 stimulates cholesteryl ester secretion in apoB-containing lipoproteins
    • Temel, R. E., Hou, L., Rudel, L. L. & Shelness, G. S. (2007). ACAT2 stimulates cholesteryl ester secretion in apoB-containing lipoproteins. J Lipid Res 48, 1618-1627.
    • (2007) J Lipid Res , vol.48 , pp. 1618-1627
    • Temel, R.E.1    Hou, L.2    Rudel, L.L.3    Shelness, G.S.4
  • 49
  • 50
    • 0346103657 scopus 로고    scopus 로고
    • Disruption of hepatitis C virus RNA replication through inhibition of host protein geranylgeranylation
    • Ye, J., Wang, C., Sumpter, R., Jr, Brown, M. S., Goldstein, J. L. & Gale, M., Jr (2003). Disruption of hepatitis C virus RNA replication through inhibition of host protein geranylgeranylation. Proc Natl Acad Sci U S A 100, 15865-15870.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 15865-15870
    • Ye, J.1    Wang, C.2    Sumpter, R.3    Brown Jr., M.S.4    Goldstein, J.L.5    Gale Jr., M.6
  • 51
    • 0347356614 scopus 로고    scopus 로고
    • Conjugated linoleic acid upregulates LDL receptor gene expression in HepG2 cells
    • Yu-Poth, S., Yin, D., Zhao, G., Kris-Etherton, P. M. & Etherton, T. D. (2004). Conjugated linoleic acid upregulates LDL receptor gene expression in HepG2 cells. J Nutr 134, 68-71.
    • (2004) J Nutr , vol.134 , pp. 68-71
    • Yu-Poth, S.1    Yin, D.2    Zhao, G.3    Kris-Etherton, P.M.4    Etherton, T.D.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.