Continuous positive airway pressure reduces blood pressure in patients with obstructive sleep apnea; A systematic review and meta-analysis with 1000 patients

Journal of Hypertension

Volumn 32, Issue 9, 2014, Pages 1762-1773

  Schein, Andressa S O ^a   Kerkhoff, Alessandra C ^a,b   Coronel, Christian C ^a   Plentz, Rodrigo D M ^a,c   Sbruzzi, Graciele ^a,b  

^a INSTITUTO DE CARDIOLOGIA DO RIO GRANDE DO SUL   (Brazil)

^b FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^c UNIVERSIDADE FEDERAL DE CIÊNCIAS DA SAÚDE DE PORTO ALEGRE   (Brazil)

Author keywords

arterial pressure; continuous positive airway pressure; hypertension; obstructive sleep apnea syndromes; sleep apnea

Indexed keywords

BLOOD PRESSURE MONITORING; BLOOD PRESSURE REGULATION; DIASTOLIC BLOOD PRESSURE; HUMAN; META ANALYSIS; POSITIVE END EXPIRATORY PRESSURE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); REVIEW; SLEEP DISORDERED BREATHING; SYSTEMATIC REVIEW; SYSTOLIC BLOOD PRESSURE; BLOOD PRESSURE; BLOOD PRESSURE MEASUREMENT; CIRCADIAN RHYTHM; COMPLICATION; HYPERTENSION; PATHOPHYSIOLOGY; PHYSIOLOGY; PROCEDURES; RISK FACTOR;

BLOOD PRESSURE; BLOOD PRESSURE DETERMINATION; BLOOD PRESSURE MONITORING, AMBULATORY; CIRCADIAN RHYTHM; CONTINUOUS POSITIVE AIRWAY PRESSURE; HUMANS; HYPERTENSION; RANDOMIZED CONTROLLED TRIALS AS TOPIC; RISK FACTORS; SLEEP APNEA, OBSTRUCTIVE;

EID: 84906098898     PISSN: 02636352     EISSN: 14735598     Source Type: Journal    
DOI: 10.1097/HJH.0000000000000250     Document Type: Review

References (51)

1. Young T, Palta M, Dempsey J, Skatrud J, Weber S, Badr S. The occurrence of sleep-disordered breathing among middle-Aged adults. N Engl J Med 1993; 328:1230-1235
2. Young T, Peppard PE, Gottlieb DJ. Epidemiology of obstructive sleep apnea: A population health perspective. Am J Respir Crit Care Med 2002; 165:1217-1239
3. Marin JM, Carrizo SJ, Vicente E, Agusti AG. Long-Term cardiovascular outcomes in men with obstructive sleep apnoea-hypopnoea with or without treatment with continuous positive airway pressure: An observational study. Lancet 2005; 365:1046-1053
4. Marshall NS, Wong KK, Liu PY, Cullen SR, Knuiman MW, Grunstein RR. Sleep apnea as an independent risk factor for all-cause mortality: The Busselton Health Study. Sleep 2008; 31:1079-1085
5. Martinez-Garcia MA, Campos-Rodriguez F, Catalan-Serra P, Soler-Cataluna JJ, Almeida-Gonzalez C, De La Cruz Moron I, et al. Cardiovascular mortality in obstructive sleep apnea in the elderly: Role of long-Term continuous positive airway pressure treatment: A prospective observational study. Am J Respir Crit Care Med 2012; 186:909-916
6. Young T, Finn L, Peppard PE, Szklo-Coxe M, Austin D, Nieto FJ, et al. Sleep disordered breathing and mortality: Eighteen-year follow-up of the Wisconsin sleep cohort. Sleep 2008; 31:1071-1078
7. Carlson JT, Hedner J, Elam M, Ejnell H, Sellgren J, Wallin BG. Augmented resting sympathetic activity in awake patients with obstructive sleep apnea. Chest 1993; 103:1763-1768
8. Gapelyuk A, Riedl M, Suhrbier A, Kraemer JF, Bretthauer G, Malberg H, et al. Cardiovascular regulation in different sleep stages in the obstructive sleep apnea syndrome. Biomed Tech (Berl) 2011; 56:207-213
9. Mediano O, Barcelo A, De La Pena M, Gozal D, Agusti A, Barbe F. Daytime sleepiness and polysomnographic variables in sleep apnoea patients. Eur Respir J 2007; 30:110-113
10. Somers VK, Dyken ME, Clary MP, Abboud FM. Sympathetic neural mechanisms in obstructive sleep apnea. J Clin Invest 1995; 96:1897-1904
11. Becker HF, Jerrentrup A, Ploch T, Grote L, Penzel T, Sullivan CE, Peter JH. Effect of nasal continuous positive airway pressure treatment on blood pressure in patients with obstructive sleep apnea. Circulation 2003; 107:68-73
12. Kapa S, Sert Kuniyoshi FH, Somers VK. Sleep apnea and hypertension: Interactions and implications for management. Hypertension 2008; 51:605-608
13. Chobanian AV, Bakris GL, Black HR, Cushman WC, Green LA, Izzo JL Jr, et al. Seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure. Hypertension 2003; 42:1206-1252
14. Lewington S, Clarke R, Qizilbash N, Peto R, Collins R. Age-specific relevance of usual blood pressure to vascular mortality: A meta-Analysis of individual data for one million adults in 61 prospective studies. Lancet 2002; 360:1903-1913
15. Barnes M, McEvoy RD, Banks S, Tarquinio N, Murray CG, Vowles N, Pierce RJ. Efficacy of positive airway pressure and oral appliance in mild to moderate obstructive sleep apnea. Am J Respir Crit Care Med 2004; 170:656-664
16. Kohler M, Pepperell JC, Casadei B, Craig S, Crosthwaite N, Stradling JR, Davies RJ. CPAP and measures of cardiovascular risk in males with OSAS. Eur Respir J 2008; 32:1488-1496
17. Narkiewicz K, Kato M, Phillips BG, Pesek CA, Davison DE, Somers VK. Nocturnal continuous positive airway pressure decreases daytime sympathetic traffic in obstructive sleep apnea. Circulation 1999; 100:2332-2335
18. Pepperell JC, Ramdassingh-Dow S, Crosthwaite N, Mullins R, Jenkinson C, Stradling JR, Davies RJ. Ambulatory blood pressure after therapeutic and subtherapeutic nasal continuous positive airway pressure for obstructive sleep apnoea: A randomised parallel trial. Lancet 2002; 359:204-210
19. Stanchina ML, Welicky LM, Donat W, Lee D, Corrao W, Malhotra A. Impact of CPAP use and age on mortality in patients with combined COPD and obstructive sleep apnea: The overlap syndrome. J Clin Sleep Med 2013; 9:767-772
20. Toraldo DM, De Nuccio F, Nicolardi G. Effects of nCPAP therapy on cardiorespiratory outcomes in obstructive sleep apnea syndrome: Compliance and technological advancements. Expert Rev Respir Med 2011; 5:41-47
21. Duran-Cantolla J, Aizpuru F, Montserrat JM, Ballester E, Teran-Santos J, Aguirregomoscorta JI, et al. Continuous positive airway pressure as treatment for systemic hypertension in people with obstructive sleep apnoea: Randomised controlled trial. BMJ 2010; 341:c5991
22. Drager LF, Pedrosa RP, Diniz PM, Diegues-Silva L, Marcondes B, Couto RB, et al. The effects of continuous positive airway pressure on prehypertension and masked hypertension in men with severe obstructive sleep apnea. Hypertension 2011; 57:549-555
23. Barbe F, Mayoralas LR, Duran J, Masa JF, Maimo A, Montserrat JM, et al. Treatment with continuous positive airway pressure is not effective in patients with sleep apnea but no daytime sleepiness. A randomized, controlled trial. Ann Intern Med 2001; 134:1015-1023
24. Robinson GV, Smith DM, Langford BA, Davies RJ, Stradling JR. Continuous positive airway pressure does not reduce blood pressure in nonsleepy hypertensive OSA patients. Eur Respir J 2006; 27:1229-1235
25. Campos-Rodriguez F, Grilo-Reina A, Perez-Ronchel J, Merino-Sanchez M, Gonzalez-Benitez MA, Beltran-Robles M, Almeida-Gonzalez C. Effect of continuous positive airway pressure on ambulatory BP in patients with sleep apnea and hypertension: A placebo-controlled trial. Chest 2006; 129:1459-1467
26. Moher D, Liberati A, Tetzlaff J, Altman DG. Preferred reporting items for systematic reviews and meta-Analyses: The PRISMA statement. Int J Surg 2010; 8:336-341
27. Robinson KA, Dickersin K. Development of a highly sensitive search strategy for the retrieval of reports of controlled trials using PubMed. Int J Epidemiol 2002; 31:150-153
28. Engleman HM, Gough K, Martin SE, Kingshott RN, Padfield PL, Douglas NJ. Ambulatory blood pressure on and off continuous positive airway pressure therapy for the sleep apnea/hypopnea syndrome: Effects in nondippers. Sleep 1996; 19:378-381
29. Norman D, Loredo JS, Nelesen RA, Ancoli-Israel S, Mills PJ, Ziegler MG, Dimsdale JE. Effects of continuous positive airway pressure versus supplemental oxygen on 24-h ambulatory blood pressure. Hypertension 2006; 47:840-845
30. Sleep-related breathing disorders in adults: Recommendations for syndrome definition and measurement techniques in clinical research. The Report of an American Academy of Sleep Medicine Task, Force. Sleep 1999; 22:667-689
31. Alonso-Fernandez A, Garcia-Rio F, Arias MA, Hernanz A, De La Pena M, Pierola J, et al. Effects of CPAP on oxidative stress and nitrate efficiency in sleep apnoea: A randomised trial. Thorax 2009; 64:581-586
32. Cross MD, Mills NL, Al-Abri M, Riha R, Vennelle M, Mackay TW, et al. Continuous positive airway pressure improves vascular function in obstructive sleep apnoea/hypopnoea syndrome: A randomised controlled trial. Thorax 2008; 63:578-583
33. Dimsdale JE, Loredo JS, Profant J. Effect of continuous positive airway pressure on blood pressure: A placebo trial. Hypertension 2000; 35 (1 Pt1):144-147
34. Hui DS, To KW, Ko FW, Fok JP, Chan MC, Ngai JC, et al. Nasal CPAP reduces systemic blood pressure in patients with obstructive sleep apnoea and mild sleepiness. Thorax 2006; 61:1083-1090
35. Kohler M, Stoewhas AC, Ayers L, Senn O, Bloch KE, Russi EW, Stradling JR. Effects of continuous positive airway pressure therapy withdrawal in patients with obstructive sleep apnea: A randomized controlled trial. Am J Respir Crit Care Med 2011; 184:1192-1199
36. Lam JC, Lam B, Yao TJ, Lai AY, Ooi CG, Tam S, et al. A randomised controlled trial of nasal continuous positive airway pressure on insulin sensitivity in obstructive sleep apnoea. Eur Respir J 2010; 35:138-145
37. Mills PJ, Kennedy BP, Loredo JS, Dimsdale JE, Ziegler MG. Effects of nasal continuous positive airway pressure and oxygen supplementation on norepinephrine kinetics and cardiovascular responses in obstructive sleep apnea. J Appl Physiol 2006; 100:343-348
38. Nguyen PK, Katikireddy CK, McConnell MV, Kushida C, Yang PC. Nasal continuous positive airway pressure improves myocardial perfusion reserve and endothelial-dependent vasodilation in patients with obstructive sleep apnea. J Cardiovasc Magn Reson 2010; 12:50
39. Patruno V, Beghi AS, Chiesa G, Malianni L, Montano AN. Different efficacy of CPAP and Auto CPAP therapy in patients with sleep apnea syndrome (SAOS): Preliminary results. Rass Di Patol Dellapparato Resp 2005; 20:107-116
40. Buchner NJ, Quack I, Stegbauer J, Woznowski M, Kaufmann A, Rump LC. Treatment of obstructive sleep apnea reduces arterial stiffness. Sleep Breath 2012; 16:123-133
41. Haentjens P, Van Meerhaeghe A, Moscariello A, De Weerdt S, Poppe K, Dupont A, Velkeniers B. The impact of continuous positive airway pressure on blood pressure in patients with obstructive sleep apnea syndrome: Evidence from a meta-Analysis of placebo-controlled randomized trials. Arch Intern Med 2007; 167:757-764
42. He J, Whelton PK. Elevated systolic blood pressure and risk of cardiovascular and renal disease: Overview of evidence from observational epidemiologic studies and randomized controlled trials. Am Heart J 1999; 138 (3 Pt 2):211-219
43. Goff DC Jr, Lloyd-Jones DM, Bennett G, ODonnell CJ, Coady S, Robinson J, et al. 2013 ACC/AHA Guideline on the Assessment of Cardiovascular Risk. J Am Coll Cardiol 2014; doi: 10.1016/j.jacc.2013.11.005
44. James PA, Oparil S, Carter BL, Cushman WC, Dennison-Himmelfarb C, Handler J, et al. 2014 evidence-based guideline for the management of high blood pressure in adults: Report from the panel members appointed to the Eighth Joint National Committee (JNC 8). JAMA 2014; 311:507-520
45. Hansen TW, Li Y, Boggia J, Thijs L, Richart T, Staessen JA. Predictive role of the nighttime blood pressure. Hypertension 2011; 57:3-10
46. Vaile JC, Stallard TJ, al-Ani M, Jordan PJ, Townend JN, Littler WA. Sleep and blood pressure: Spontaneous baroreflex sensitivity in dippers and nondippers. J Hypertens 1996; 14:1427-1432
47. Phillips CL, ODriscoll DM. Hypertension and obstructive sleep apnea. Nat Sci Sleep 2013; 5:43-52
48. Frattola A, Parati G, Cuspidi C, Albini F, Mancia G. Prognostic value of 24-h blood pressure variability. J Hypertens 1993; 11:1133-1137
49. White WB, Dey HM, Schulman P. Assessment of the daily blood pressure load as a determinant of cardiac function in patients with mild-To-moderate hypertension. Am Heart J 1989; 118:782-795
50. Montesi SB, Edwards BA, Malhotra A, Bakker JP. The effect of continuous positive airway pressure treatment on blood pressure: A systematic review and meta-Analysis of randomized controlled trials. J Clin Sleep Med 2012; 8:587-596
51. Fava C, Dorigoni S, Dalle Vedove F, Danese E, Montagnana M, Guidi GC, et al. Effect of continuous positive airway pressure (Cpap) on blood pressure in patients with obstructive sleep apnea/hypopnea. A systematic review and meta-Analysis. Chest 2014; 145:762-771.