Catheter-based renal denervation versus intensified medical treatment in patients with resistant hypertension: Rationale and design of a multicenter randomized study-PRAGUE-15

Cor et Vasa

Volumn 56, Issue 3, 2014, Pages

  Tousek, Petr ^a   Widimsky, Jiri ^b   Rosa, Jan ^a,b   Curila, Karol ^a   Branny, Marian ^c   Nykl, Igor ^c   Taborsky, Milos ^d   Vaclavik, Jan ^d   Widimsky, Petr ^a  

^a CHARLES UNIVERSITY   (Czech Republic)

^b CHARLES UNIVERSITY   (Czech Republic)

^c Nemocnice Podlesí   (Czech Republic)

^d UNIVERSITY HOSPITAL OLOMOUC   (Czech Republic)

Author keywords

Adherence to treatment; Ambulatory blood pressure monitoring; Catheter based renal denervation; Resistant hypertension; Spironolactone

Indexed keywords

SPIRONOLACTONE;

ADULT; ARTICLE; BLOOD PRESSURE MONITORING; CATHETER BASED RENAL DENERVATION; DIASTOLIC BLOOD PRESSURE; DOUBLE BLIND PROCEDURE; FEMALE; HUMAN; KIDNEY DENERVATION; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; PATIENT COMPLIANCE; RESISTANT HYPERTENSION; SYSTOLIC BLOOD PRESSURE; TREATMENT DURATION;

EID: 84906069099     PISSN: 00108650     EISSN: 18037712     Source Type: Journal    
DOI: 10.1016/j.crvasa.2014.04.004     Document Type: Article

References (24)

1. P.M. Kearney, M. Whelton, K. Reynolds, et al., Global burden of hypertension: analysis of worldwide data, Lancet 365 (9455) (2005) 217-223.
2. C.M. Lawes, S. Vander Hoorn, A. Rodgers, Global burden of blood-pressure-related disease, Lancet 371 (9623) (2001) 1513-1518, 2008.
3. S. Lewington, R. Clarke, N. Qizilbash, et al., Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies, Lancet 360 (9349) (2002) 1903-1913.
4. D.M. Lloyd-Jones, J.C. Evans, D. Levy, Hypertension in adults across the age spectrum: current outcomes and control in the community, Journal of the American Medical Association 294 (4) (2005) 466-472.
5. D.A. Calhoun, D. Jones, S. Textor, et al., Resistant hypertension: diagnosis, evaluation, and treatment: a scientific statement from the American Heart Association Professional Education Committee of the Council for High Blood Pressure Research, Circulation 117 (25) (2008) e510-e526.
6. G. Mancia, R. Fagard, K. Nirkiewicz, et al., 2013 ESH/ESC Guidelines for the management of arterial hypertension: The Task Force for the management of arterial hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC), European Heart Journal 34 (28) (2013) 2159-2219.
7. Y. Huan, D.L. Cohen, Renal denervation: a potential new treatment for severe hypertension, Clinical Cardiology 36 (1) (2013) 10-14.
8. M.D. Esler, H. Krum, P.A. Sobotka, et al., Renal sympathetic denervation in patients with treatment-resistant hypertension (the Symplicity HTN-2 Trial): a randomised controlled trial, Lancet 376 (9756) (2010) 1903-1909.
9. D.L. Bhatt, D.E. Kandzari, W.W. O'Neill, et al., A controlled trial of renal denervation for resistant hypertension, New England Journal of Medicine 370 (15) (2014) 1393-1401.
10. P. Widimsky, J. Filipovsky, J. Widimsky Jr., et al., Expert consensus statement of the Czech Society of Cardiology and the Czech Society of Hypertension on catheter-based sympathetic renal denervation procedures (RDN) in the Czech Republic, Cor et Vasa 54 (2012) e108-e112.
11. J. Vaclavik, R. Sedlak, M. Plachy, et al., Addition of spironolactone in patients with resistant arterial hypertension (ASPIRANT): a randomized, double-blind, placebo-controlled trial, Hypertension 57 (6) (2011) 1069-1075.
12. J.W. Funder, R.M. Carrey, C. Fardella, et al., Case detection, diagnosis, and treatment of patients with primary aldosteronism: an endocrine society clinical practice guideline, Journal of Clinical Endocrinology and Metabolism 93 (9) (2008) 3266-3281.
13. B. Strauch, O. Petrak, T. Zelinka, et al., Precise assessment of noncompliance with the antihypertensive therapy in patients with resistant hypertension using toxicological serum analysis, Journal of Hypertension 31 (12) (2013) 2455-2461.
14. O. Gonzalez, R.M. Alonso, N. Ferreirós, et al., LC-MS/MS method for the determination of several drugs used in combined cardiovascular therapy in human plasma, Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences 878 (28) (2010) 2685-2692.
15. L. Chytil, B. Strauch, J. Cvacka, et al., Determination of doxazosin and verapamil in human serum by fast LC-MS/ MS: application to document non-compliance of patients, Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences 878 (30) (2010) 3167-3173.
16. F. Mahfoud, C. Ukena, R.E. Schmieder, et al., Ambulatory blood pressure changes after renal sympathetic denervation in patients with resistant hypertension, Circulation 128 (2) (2013) 132-140.
17. F. de Souza, E. Muxfeldt, R. Fiszman, et al., Efficacy of spironolactone therapy in patients with true resistant hypertension, Hypertension 55 (1) (2010) 147-152.
18. S.G. Worthley, C.P. Tsioufis, M.I. Worthley, et al., Safety and efficacy of a multi-electrode renal sympathetic denervation system in resistant hypertension: the EnligHTN I trial, European Heart Journal 34 (28) (2013) 2132-2140.
19. Symplicity HTN-1 Investigators, Catheter-based renal sympathetic denervation for resistant hypertension: durability of blood pressure reduction out to 24 months, Hypertension 57 (5) (2011) 911-917.
20. P. Widimsky, P. Osmancik, J. Widimsky Jr., et al., Renal denervation: the hope for patients with refractory hypertension? Cor et Vasa 53 (2011) 517-521.
21. G. Grassi, R. Facchetti, G. Seravalle, et al., Home and ambulatory blood pressure in resistant hypertension, EuroIntervention 9 (Suppl. R) (2013) R35-R41.
22. A. Persu, M. Azizi, M. Burnier, et al., Residual effect of renal denervation in patients with truly resistant hypertension, Hypertension 62 (3) (2013) 450-452.
23. D.E. Kandzari, D.L. Bhatt, P.A. Sobotka, et al., Catheter- based renal denervation for resistant hypertension: rationale and design of the SYMPLICITY HTN-3 Trial, Clinical Cardiology 35 (9) (2012) 528-535.
24. R. Sega, R. Facchetti, M. Bombelli, et al., Prognostic value of ambulatory and home blood pressures compared with office blood pressure in the general population: follow-up results from the Pressioni Arteriose Monitorate e Loro Associazioni (PAMELA) study, Circulation 111 (14) (2005) 1777-1783.