Development and implementation of a two-semester introductory organic-bioorganic chemistry sequence: Conclusions from the first six years

Journal of Chemical Education

Volumn 91, Issue 8, 2014, Pages 1169-1173

  Goess, Brian C ^a  

^a FURMAN UNIVERSITY   (United States)

Author keywords

Bioorganic Chemistry; Curriculum; Interdisciplinary Multidisciplinary; Organic Chemistry; Second Year Undergraduate

Indexed keywords

EID: 84906057050     PISSN: 00219584     EISSN: 19381328     Source Type: Journal    
DOI: 10.1021/ed400264w     Document Type: Article

References (23)

1. Dagas, H. Teaching Bioorganic Chemistry: An Introductory Course J. Chem. Educ. 1992, 69, 268-269
2. Breslow, R. Bioorganic Chemistry: A Natural and Unnatural Science J. Chem. Educ. 1998, 75, 705-718
3. Reingold, I. D. Bioorganic First: A New Model for the College Chemistry Curriculum J. Chem. Educ. 2001, 78, 869-871
4. AAMC-HHMI Committee Report (2009), " Scientific Foundations for Future Physicians." https://www.aamc.org/download/271072/data/ scientificfoundationsforfuturephysicians.pdf (accessed May 2014).
5. McMurry, J. E. Organic Chemistry: With Biological Applications, 2 nd ed.; Brooks/Cole: Belmont, 2010.
6. Reingold, I. D. Organic Chemistry (Updated 2nd ed.): An Introductory Text Emphasizing Biological Connections; McGraw Hill Learning Solutions: Belmont, 2011.
7. Though we anticipate many excellent texts will be forthcoming, our unique solution to this problem included the creation of a wiki textbook that is written and curated collectively by every student who has taken the course. An online textbook along these lines is also available: Soderberg, T. Organic Chemistry with a Biological Emphasis. http://chemwiki.ucdavis.edu/Organic/ Chemistry/Organic/Chemistry/With/a/Biological/Emphasis (accessed May 2014).
8. McMurry, J. E. Fundamentals of Organic Chemistry, 7 th ed.; Brooks/Cole: Belmont, 2011.
9. Bruice, P. Y. Essential Organic Chemistry, 2 nd ed.; Prentice Hall: Essex, 2009.
10. Hart, D. J.; Hadad, C. M.; Craine, L. E.; Hart, H. Organic Chemistry A Short Course; Brooks/Cole: Belmont, 2012.
11. Van Vranken, D.; Weiss, G. A. Introduction to Bioorganic Chemistry and Chemical Biology; Garland Science: New York, 2012.
12. McMurry, J.; Tadhg, B. The Organic Chemistry of Biological Pathways; Roberts and Company: Englewood, 2005.
13. Silverman, R. B. The Organic Chemistry of Enzyme-Catalyzed Reactions, 2 nd ed.; Academic Press: London, 2002.
14. Bugg, T. H. D. Introduction to Enzyme and Coenzyme Chemistry, 3 rd ed.; Wiley: Oxford, 2012.
15. Dewick, P. M. Medicinal Natural Products: A Biosynthetic Approach, 3 rd ed.; Wiley: Chichester, 2009.
16. Lee, M. Microscale Yeast Mediated Enantiospecific Reduction of Vanillin, And the Absolute Configuration of (-)-(R)-[α]-Deuteriovanillyl Alcohol: A Bioorganic Chemistry Experiment J. Chem. Educ. 1993, 70, A155-A158
17. Lee, M. Enzymatic Synthesis of (S)-(-)-γ-Methyl-γ- butyrolactone from Racemic Methyl γ-Hydroxypentanoate: A Microscale Advanced Bioorganic Chemistry Laboratory Project J. Chem. Educ. 1998, 75, 217-219
18. Lee, M.; Huntington, M. A More Affordable Undergraduate Experiment on the Reduction of Acetophenone by Yeast J. Chem. Educ. 1998, 75, A62-A66
19. Brunauer, L. S.; Mogannam, A. C.; Hwee, W. B.; Chen, J. Y. Synthesis of Quaternary Ammonium Salts of Tricyclic Cationic Drugs: A One-Pot Synthesis for the Bioorganic Chemistry Laboratory J. Chem. Educ. 2007, 84, 1992-1994
20. Simon, E.; Cook, K.; Pritchard, M. R.; Stripe, W.; Bruch, M.; Bendinskas, K. Glycosidation of Methanol with Ribose: An Interdisciplinary Undergraduate Laboratory Experiment J. Chem. Educ. 2010, 87, 739-741
21. Narzi, M. M.; Samat, F. D.; Kavanagh, P. V.; Walsh, J. J. Nature's Cholesterol-Lowering Drug: Isolation and Structure Elucidation of Lovastatin from Red Yeast Rice-Containing Dietary Supplements J. Chem. Educ. 2012, 89, 138-140
22. 5th Comprehensive Review of the Medical College Admission Test (MCAT): Final MCAT Recommendations. https://www.aamc.org/download/275126/data/ finalrecommendationsupdate.pdf (accessed May 2014).
23. Robinson, R. A Synthesis of Tropinone J. Chem. Soc. 1917, 111, 762-768