Quantitative regional differences in corneal endothelial abnormalities in the central and peripheral zones in Fuchs' endothelial corneal dystrophy

Investigative Ophthalmology and Visual Science

Volumn 55, Issue 8, 2014, Pages 5090-5098

  Fujimoto, Hisataka ^a   Maeda, Naoyuki ^a   Soma, Takeshi ^a   Oie, Yoshinori ^a   Koh, Shizuka ^a   Tsujikawa, Motokazu ^a   Nishida, Kohji ^a  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Endothelium; Fuchs' endothelial corneal dystrophy; Peripheral; Specular microscopy

Indexed keywords

ENDOTHELIUM; FUCHS' ENDOTHELIAL CORNEAL DYSTROPHY; PERIPHERAL; SPECULAR MICROSCOPY;

ADULT; AGED; AGED, 80 AND OVER; DISEASE PROGRESSION; ENDOTHELIUM, CORNEAL; FEMALE; FOLLOW-UP STUDIES; FUCHS' ENDOTHELIAL DYSTROPHY; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; MALE; MICROSCOPY, CONFOCAL; MIDDLE AGED; RETROSPECTIVE STUDIES; SEVERITY OF ILLNESS INDEX;

EID: 84906053061     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.14-14249     Document Type: Article

References (45)

1. Fuchs E. Dystrophia epithelialis corneae. Graefes Arch Clin Exp Ophthalmol. 1910;76:478-508.
2. Wilson SE, Bourne WM. Fuchs' dystrophy. Cornea. 1988;7:2-18.
3. Burns RR, Bourne WM, Brubaker RF. Endothelial function in patients with cornea guttata. Invest Ophthalmol Vis Sci. 1981; 20:77-85.
4. Adamis AP, Filatov V, Tripathi BJ, et al. Fuchs' endothelial dystrophy of the cornea. Surv Ophthalmol. 1993;38:149-168.
5. Schmedt T, Silva MM, Ziaei A, et al. Molecular bases of corneal endothelial dystrophies. Exp Eye Res. 2012;95:24-34.
6. Lorenzetti DWC, Votila MH, Parikh N, Kaufman HE. Central cornea guttata. Am J Ophthalmol. 1967;64:1155-1158.
7. Krachmer JH, Purcell JJ Jr, Young CW, et al. Corneal endothelial dystrophy. A study of 64 families. Arch Ophthalmol. 1978;96:2036-2039.
8. Brunette I, Sherknies D, Terry MA, et al. 3-D characterization of the corneal shape in Fuchs' dystrophy and pseudophakic keratopathy. Invest Ophthalmol Vis Sci. 2011;52:206-214.
9. Melles GR, Eggink FA, Lander F, et al. A surgical technique for posterior lamellar keratoplasty. Cornea. 1998;17:618-626.
10. Terry MA, Ousley PJ. Replacing the endothelium without corneal surface incisions or sutures: the first United States clinical series using the deep lamellar endothelial keratoplasty procedure. Ophthalmology. 2003;110:755-764.
11. Price FW Jr, Price MO. Descemet's stripping with endothelial keratoplasty in 200 eyes: early challenges and techniques to enhance donor adherence. J Cataract Refract Surg. 2006;32: 411-418.
12. Lee WB, Jacobs DS, Musch DC, et al. Descemet's stripping endothelial keratoplasty: safety and outcomes: a report by the American Academy of Ophthalmology. Ophthalmology. 2009; 116:1818-1830.
13. Melles GR, Ong TS, Ververs B, van der Wees J. Descemet membrane endothelial keratoplasty (DMEK). Cornea. 2006; 25:987-990.
14. Price MO, Giebel AW, Fairchild KM, Price FW Jr. Descemet's membrane endothelial keratoplasty: prospective multicenter study of visual and refractive outcomes and endothelial survival. Ophthalmology. 2009;116:2361-2368.
15. Waring GO, Bourne WM, Edelhauser HF, et al. The cornea1 endothelium; normal and pathologic structure and function. Ophthalmology. 1982;89:531-590.
16. Kuwabara T, Quevedo AR, Logan DC. An experimental study of dichloroethane poisoning. Arch Ophthalmol. 1968;79:321-330.
17. Louttit MD, Kopplin LJ, Igo RP Jr, et al. FECD Genetics Multi-Center Study Group. A multicenter study to map genes for Fuchs' endothelial corneal dystrophy: baseline characteristics and heritability. Cornea. 2012;31:26-35.
18. Zeger SL, Liang KY. Longitudinal data analysis for discrete and continuous outcomes. Biometrics. 1986;42:121-130.
19. Ratcliffe SJ, Shults J. GEEQBOX: a MATLAB toolbox for generalized estimating equations and quasi-least squares. J Stat Softw. 2008;25:1-14.
20. Bevington PR. Data Reduction and Error Analysis for the Physical Sciences. New York, NY: McGraw-Hill; 1969.
21. Boote C, Hayes S, Abahussin M, et al. Mapping collagen organization in the human cornea: left and right eyes are structurally distinct. Invest Ophthalmol Vis Sci. 2006;47:901-908.
22. Giasson CJ, Solomon LD, Polse KA. Morphometry of corneal endothelium in patients with corneal guttata. Ophthalmology. 2007;114:1469-1475.
23. Naumann GO, Schlötzer-Schrehardt U. Keratopathy in pseudoexfoliation syndrome as a cause of corneal endothelial decompensation: a clinicopathologic study. Ophthalmology. 2000;107:1111-1124.
24. Waring GO, Laibson PR, Rodrigues MM. Clinical and pathologic alterations of Descemet's membrane with emphasis on endothelial metaplasia. Surv Ophthalmol. 1974;18:325-368.
25. Repp DJ, Hodge DO, Baratz KH, et al. Fuchs' endothelial corneal dystrophy: subjective grading versus objective grading based on the central-to-peripheral thickness ratio. Ophthalmology. 2013;120:687-694.
26. Graves B. A bilateral chronic affection of the endothelial face of the cornea of elderly persons with an account of the technical and clinical principles of its slit-lamp observation. Br J Ophthalmol. 1924;8:502-544.
27. Friedenwald H, Friedenwald JS. Epithelial dystrophy of the cornea. Br J Ophthalmol. 1925;9:14-20.
28. Jun AS. One hundred years of Fuchs' dystrophy. Ophthalmology. 2010;117:859-860.
29. Maurice D. Cellular membrane activity in the corneal endothelium. Invest Ophthalmol. 1968;24:1094-1095.
30. McCarey BE. Noncontact specular microscopy of corneal endothelium. Invest Ophthalmol Vis Sci. 1978;17:118.
31. Laing RA, Leibowitz HM, Oak SS, et al. Endothelial mosaic in Fuchs' dystrophy. A qualitative evaluation with the specular microscope. Arch Ophthalmol. 1981;99:80-83.
32. Olsen T. On the significance of a low endothelial cell density in Fuchs' endothelial dystrophy. A specular microscopic study. Acta Ophthalmol. 1980;58:111-116.
33. Kitagawa K, Fujisawa A, Mizuno T, Sasaki K. Twenty-three cases of primary cornea guttata. Jpn J Ophthalmol. 2001;45: 93-98.
34. Gottsch JD, Sundin OH, Rencs EV, et al. Analysis and documentation of progression of Fuchs corneal dystrophy with retroillumination photography. Cornea. 2006;25:485-489.
35. Yamagami S, Yokoo S, Mimura T, et al. Distribution of precursors in human corneal stromal cells and endothelial cells. Ophthalmology. 2007;114:433-439.
36. Amann J, Holley GP, Lee SB, et al. Increased endothelial cell density in the paracentral and peripheral regions of the human cornea. Am J Ophthalmol. 2003;135:584-590.
37. Pitts DG, Cullen AP, Hacker PD. Ocular effects of ultraviolet radiation from 295 to 365 nm. Invest Ophthalmol Vis Sci. 1977;16:932-939.
38. Rosenblum P, Stark WJ, Maumenee IH, et al. Hereditary Fuchs' dystrophy. Am J Ophthalmol. 1980;90:455-462.
39. Wilson SE, Bourne WM, O'Brien PC, et al. Endothelial function and aqueous humor flow rate in patients with Fuchs' dystrophy. Am J Ophthalmol. 1988;106:270-278.
40. Wilson SE, Bourne WM, Maguire LJ, et al. Aqueous humor composition in Fuchs' dystrophy. Invest Ophthalmol Vis Sci. 1989;30:449-453.
41. Patel SV, Baratz KH, Hodge DO, et al. The effect of corneal light scatter on vision after Descemet stripping with endothelial keratoplasty. Arch Ophthalmol. 2009;127:153-160.
42. Nielsen E, Hjortdal J. Visual acuity and contrast sensitivity after posterior lamellar keratoplasty. Acta Ophthalmol. 2012;90: 756-760.
43. McLaren JW, Bachman LA, Kane KM, Patel SV. Objective assessment of the corneal endothelium in Fuchs' endothelial dystrophy. Invest Ophthalmol Vis Sci. 2014;55:1184-1190.
44. Hatou S, Shimmura S, Shimazaki J, et al. Mathematical projection model of visual loss due to Fuchs' corneal dystrophy. Invest Ophthalmol Vis Sci. 2011;52:7888-7893.
45. Martola EL, Baum JL. Central and peripheral corneal thickness. A clinical study. Arch Ophthalmol. 1968;79:28-30.