Diterpenoid C of Radix Curcumae: An inhibitor of proliferation and inducer of apoptosis in human colon adenocarcinoma cells acting via inhibiting MAPK signaling pathway

Pharmaceutical Biology

Volumn 52, Issue 9, 2014, Pages 1158-1165

  Shen, Yan ^a,b   Lu, Bin ^a   Zhang, Shuo ^a   Ma, Zhong Jun ^c  

^a THE FIRST AFFILIATED HOSPITAL OF ZHEJIANG CHINESE MEDICAL UNIVERSITY   (China)

^b ZHEJIANG CHINESE MEDICAL UNIVERSITY   (China)

^c ZHEJIANG UNIVERSITY   (China)

Author keywords

Apoptosis; Caspase 3; Colon cancer; Diterpenoid C; MAPK; SW620 cell; Zingiberaceae

Indexed keywords

ANTINEOPLASTIC AGENT; CASPASE 3; DITERPENOID; DITERPENOID C; FLUOROURACIL; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; OXALIPLATIN; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG; DITERPENE; DITERPENOID C, RADIX CURCUMAE; PLATINUM COMPLEX;

ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CELL CYCLE ARREST; COLON ADENOCARCINOMA; CONCENTRATION RESPONSE; CONTROLLED STUDY; CURCUMA; HUMAN; HUMAN CELL; IC 50; PLANT ROOT; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; ADENOCARCINOMA; CELL CYCLE CHECKPOINT; CELL PROLIFERATION; CHEMISTRY; COLONIC NEOPLASMS; COMPARATIVE STUDY; DRUG EFFECTS; IC50; ISOLATION AND PURIFICATION; METABOLISM; PATHOLOGY; TIME; TUMOR CELL LINE;

ADENOCARCINOMA; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CASPASE 3; CELL CYCLE CHECKPOINTS; CELL LINE, TUMOR; CELL PROLIFERATION; COLONIC NEOPLASMS; CURCUMA; DITERPENES; FLUOROURACIL; HUMANS; INHIBITORY CONCENTRATION 50; MAP KINASE SIGNALING SYSTEM; ORGANOPLATINUM COMPOUNDS; TIME FACTORS;

EID: 84906052551     PISSN: 13880209     EISSN: 17445116     Source Type: Journal    
DOI: 10.3109/13880209.2013.879907     Document Type: Article

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