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Volumn 193, Issue 4, 2014, Pages 1709-1716

Increased antitumor effects using IL-2 with Anti-TGF-β reveals competition between mouse NK and CD8 T Cells

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; INTERLEUKIN 2; INTERLEUKIN 6; LIVER ENZYME; NATURAL KILLER CELL RECEPTOR NKG2D; TRANSFORMING GROWTH FACTOR BETA ANTIBODY;

EID: 84905992207     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1400034     Document Type: Article
Times cited : (36)

References (54)
  • 1
    • 67650433317 scopus 로고    scopus 로고
    • Natural killer cell-based immunotherapy in cancer: Current insights and future prospects
    • Sutlu, T., and E. Alici. 2009. Natural killer cell-based immunotherapy in cancer: current insights and future prospects. J. Intern. Med. 266: 154-181.
    • (2009) J. Intern. Med , vol.266 , pp. 154-181
    • Sutlu, T.1    Alici, E.2
  • 3
    • 79959845267 scopus 로고    scopus 로고
    • Individual patient data meta-Analysis of randomized trials evaluating IL-2 monotherapy as remission maintenance therapy in acute myeloid leukemia
    • Buyse, M., P. Squifflet, B. J. Lange, T. A. Alonzo, R. A. Larson, J. E. Kolitz, S. L. George, C. D. Bloomfield, S. Castaigne, S. Chevret, et al. 2011. Individual patient data meta-Analysis of randomized trials evaluating IL-2 monotherapy as remission maintenance therapy in acute myeloid leukemia. Blood 117: 7007-7013.
    • (2011) Blood , vol.117 , pp. 7007-7013
    • Buyse, M.1    Squifflet, P.2    Lange, B.J.3    Alonzo, T.A.4    Larson, R.A.5    Kolitz, J.E.6    George, S.L.7    Bloomfield, C.D.8    Castaigne, S.9    Chevret, S.10
  • 4
    • 0024490846 scopus 로고
    • Toxicity and therapeutic efficacy of highdose interleukin 2. in vivo infusion of antibody to NK-1.1 attenuates toxicity without compromising efficacy against murine leukemia
    • Peace, D. J., and M. A. Cheever. 1989. Toxicity and therapeutic efficacy of highdose interleukin 2. In vivo infusion of antibody to NK-1.1 attenuates toxicity without compromising efficacy against murine leukemia. J. Exp. Med. 169: 161-173.
    • (1989) J. Exp. Med , vol.169 , pp. 161-173
    • Peace, D.J.1    Cheever, M.A.2
  • 5
    • 84855804372 scopus 로고    scopus 로고
    • Interleukin-15 biology and its therapeutic implications in cancer
    • Steel, J. C., T. A. Waldmann, and J. C. Morris. 2012. Interleukin-15 biology and its therapeutic implications in cancer. Trends Pharmacol. Sci. 33: 35-41.
    • (2012) Trends Pharmacol. Sci , vol.33 , pp. 35-41
    • Steel, J.C.1    Waldmann, T.A.2    Morris, J.C.3
  • 7
    • 20644472421 scopus 로고    scopus 로고
    • Transforming growth factor-beta controls T helper type 1 cell development through regulation of natural killer cell interferon-gamma
    • Laouar, Y., F. S. Sutterwala, L. Gorelik, and R. A. Flavell. 2005. Transforming growth factor-beta controls T helper type 1 cell development through regulation of natural killer cell interferon-gamma. Nat. Immunol. 6: 600-607.
    • (2005) Nat. Immunol , vol.6 , pp. 600-607
    • Laouar, Y.1    Sutterwala, F.S.2    Gorelik, L.3    Flavell, R.A.4
  • 8
    • 33750691006 scopus 로고    scopus 로고
    • The role of regulatory T cells in the control of natural killer cells: Relevance during tumor progression
    • Ghiringhelli, F., C. Ménard, F. Martin, and L. Zitvogel. 2006. The role of regulatory T cells in the control of natural killer cells: relevance during tumor progression. Immunol. Rev. 214: 229-238.
    • (2006) Immunol. Rev , vol.214 , pp. 229-238
    • Ghiringhelli, F.1    Ménard, C.2    Martin, F.3    Zitvogel, L.4
  • 11
    • 84865787544 scopus 로고    scopus 로고
    • Molecular pathways: Targeting the TGF-b pathway for cancer therapy
    • Smith, A. L., T. P. Robin, and H. L. Ford. 2012. Molecular pathways: targeting the TGF-b pathway for cancer therapy. Clin. Cancer Res. 18: 4514-4521.
    • (2012) Clin. Cancer Res , vol.18 , pp. 4514-4521
    • Smith, A.L.1    Robin, T.P.2    Ford, H.L.3
  • 12
    • 44249100929 scopus 로고    scopus 로고
    • TGF beta secreted by B16 melanoma antagonizes cancer gene immunotherapy bystander effect
    • Penafuerte, C., and J. Galipeau. 2008. TGF beta secreted by B16 melanoma antagonizes cancer gene immunotherapy bystander effect. Cancer Immunol. Immunother. 57: 1197-1206.
    • (2008) Cancer Immunol. Immunother , vol.57 , pp. 1197-1206
    • Penafuerte, C.1    Galipeau, J.2
  • 13
    • 70349339390 scopus 로고    scopus 로고
    • Disruption of TGF-beta signaling prevents the generation of tumor-sensitized regulatory T cells and facilitates therapeutic antitumor immunity
    • Petrausch, U., S. M. Jensen, C. Twitty, C. H. Poehlein, D. P. Haley, E. B. Walker, and B. A. Fox. 2009. Disruption of TGF-beta signaling prevents the generation of tumor-sensitized regulatory T cells and facilitates therapeutic antitumor immunity. J. Immunol. 183: 3682-3689.
    • (2009) J. Immunol , vol.183 , pp. 3682-3689
    • Petrausch, U.1    Jensen, S.M.2    Twitty, C.3    Poehlein, C.H.4    Haley, D.P.5    Walker, E.B.6    Fox, B.A.7
  • 14
    • 45549085803 scopus 로고    scopus 로고
    • An anti-transforming growth factor beta antibody suppresses metastasis via cooperative effects on multiple cell compartments
    • Nam, J. S., M. Terabe, M. Mamura, M. J. Kang, H. Chae, C. Stuelten, E. Kohn, B. Tang, H. Sabzevari, M. R. Anver, et al. 2008. An anti-transforming growth factor beta antibody suppresses metastasis via cooperative effects on multiple cell compartments. Cancer Res. 68: 3835-3843.
    • (2008) Cancer Res , vol.68 , pp. 3835-3843
    • Nam, J.S.1    Terabe, M.2    Mamura, M.3    Kang, M.J.4    Chae, H.5    Stuelten, C.6    Kohn, E.7    Tang, B.8    Sabzevari, H.9    Anver, M.R.10
  • 15
    • 45849090359 scopus 로고    scopus 로고
    • Treatment of transforming growth factorbeta-insensitive mouse Renca tumor by transforming growth factor-beta elimination
    • Perry, K., L. Wong, V. Liu, I. Park, Q. Zhang, V. Rejen, X. Huang, N. D. Smith, B. Jovanovic, S. Lonning, et al. 2008. Treatment of transforming growth factorbeta-insensitive mouse Renca tumor by transforming growth factor-beta elimination. Urology 72: 225-229.
    • (2008) Urology , vol.72 , pp. 225-229
    • Perry, K.1    Wong, L.2    Liu, V.3    Park, I.4    Zhang, Q.5    Rejen, V.6    Huang, X.7    Smith, N.D.8    Jovanovic, B.9    Lonning, S.10
  • 16
    • 29444455376 scopus 로고    scopus 로고
    • NKG2D in NK and T cell-mediated immunity
    • Ogasawara, K., and L. L. Lanier. 2005. NKG2D in NK and T cell-mediated immunity. J. Clin. Immunol. 25: 534-540.
    • (2005) J. Clin. Immunol , vol.25 , pp. 534-540
    • Ogasawara, K.1    Lanier, L.L.2
  • 18
    • 70350738483 scopus 로고    scopus 로고
    • Synergistic enhancement of CD8+ T cell-mediated tumor vaccine efficacy by an anti-transforming growth factorbeta monoclonal antibody
    • Terabe, M., E. Ambrosino, S. Takaku, J. J. O'Konek, D. Venzon, S. Lonning, J. M. McPherson, and J. A. Berzofsky. 2009. Synergistic enhancement of CD8+ T cell-mediated tumor vaccine efficacy by an anti-transforming growth factorbeta monoclonal antibody. Clin. Cancer Res. 15: 6560-6569.
    • (2009) Clin. Cancer Res , vol.15 , pp. 6560-6569
    • Terabe, M.1    Ambrosino, E.2    Takaku, S.3    O'Konek, J.J.4    Venzon, D.5    Lonning, S.6    McPherson, J.M.7    Berzofsky, J.A.8
  • 19
    • 51649084785 scopus 로고    scopus 로고
    • Combination therapy using IL-2 and anti-CD25 results in augmented natural killer cell-mediated antitumor responses
    • Hallett, W. H., E. Ames, M. Alvarez, I. Barao, P. A. Taylor, B. R. Blazar, and W. J. Murphy. 2008. Combination therapy using IL-2 and anti-CD25 results in augmented natural killer cell-mediated antitumor responses. Biol. Blood Marrow Transplant. 14: 1088-1099.
    • (2008) Biol. Blood Marrow Transplant , vol.14 , pp. 1088-1099
    • Hallett, W.H.1    Ames, E.2    Alvarez, M.3    Barao, I.4    Taylor, P.A.5    Blazar, B.R.6    Murphy, W.J.7
  • 22
    • 0034660066 scopus 로고    scopus 로고
    • Synergistic effects of in vivo depletion of Ly-49A and Ly-49G2 natural killer cell subsets in the rejection of H2(b) bone marrow cell allografts
    • Raziuddin, A., M. Bennett, R. Winkler-Pickett, J. R. Ortaldo, D. L. Longo, and W. J. Murphy. 2000. Synergistic effects of in vivo depletion of Ly-49A and Ly-49G2 natural killer cell subsets in the rejection of H2(b) bone marrow cell allografts. Blood 95: 3840-3844.
    • (2000) Blood , vol.95 , pp. 3840-3844
    • Raziuddin, A.1    Bennett, M.2    Winkler-Pickett, R.3    Ortaldo, J.R.4    Longo, D.L.5    Murphy, W.J.6
  • 26
    • 0037306606 scopus 로고    scopus 로고
    • Therapeutic role of TGF-beta-neutralizing antibody in mouse cyclosporin A nephropathy: Morphologic improvement associated with functional preservation
    • Ling, H., X. Li, S. Jha, W. Wang, L. Karetskaya, B. Pratt, and S. Ledbetter. 2003. Therapeutic role of TGF-beta-neutralizing antibody in mouse cyclosporin A nephropathy: morphologic improvement associated with functional preservation. J. Am. Soc. Nephrol. 14: 377-388.
    • (2003) J. Am. Soc. Nephrol , vol.14 , pp. 377-388
    • Ling, H.1    Li, X.2    Jha, S.3    Wang, W.4    Karetskaya, L.5    Pratt, B.6    Ledbetter, S.7
  • 28
    • 84905970560 scopus 로고    scopus 로고
    • Therapeutic applications: Natural killer cells in the clinic
    • Miller, J. S. 2013. Therapeutic applications: natural killer cells in the clinic. Hematology Am. Soc. Hematol. Educ. Prog. 2013: 247-253.
    • (2013) Hematology Am. Soc. Hematol. Educ. Prog , vol.2013 , pp. 247-253
    • Miller, J.S.1
  • 29
    • 31144449386 scopus 로고    scopus 로고
    • CD27 dissects mature NK cells into two subsets with distinct responsiveness and migratory capacity
    • Hayakawa, Y., and M. J. Smyth. 2006. CD27 dissects mature NK cells into two subsets with distinct responsiveness and migratory capacity. J. Immunol. 176: 1517-1524.
    • (2006) J. Immunol , vol.176 , pp. 1517-1524
    • Hayakawa, Y.1    Smyth, M.J.2
  • 31
    • 0042834325 scopus 로고    scopus 로고
    • An IL-2-dependent switch between CD95 signaling pathways sensitizes primary human T cells toward CD95-mediated activationinduced cell death
    • Schmitz, I., A. Krueger, S. Baumann, H. Schulze-Bergkamen, P. H. Krammer, and S. Kirchhoff. 2003. An IL-2-dependent switch between CD95 signaling pathways sensitizes primary human T cells toward CD95-mediated activationinduced cell death. J. Immunol. 171: 2930-2936.
    • (2003) J. Immunol , vol.171 , pp. 2930-2936
    • Schmitz, I.1    Krueger, A.2    Baumann, S.3    Schulze-Bergkamen, H.4    Krammer, P.H.5    Kirchhoff, S.6
  • 32
    • 70350471155 scopus 로고    scopus 로고
    • Activating receptors promote NK cell expansion for maintenance. IL-10 production and CD8 T cell regulation during viral infection
    • Lee, S. H., K. S. Kim, N. Fodil-Cornu, S. M. Vidal, and C. A. Biron. 2009. Activating receptors promote NK cell expansion for maintenance, IL-10 production and CD8 T cell regulation during viral infection. J. Exp. Med. 206: 2235-2251.
    • (2009) J. Exp. Med , vol.206 , pp. 2235-2251
    • Lee, S.H.1    Kim, K.S.2    Fodil-Cornu, N.3    Vidal, S.M.4    Biron, C.A.5
  • 33
    • 84855999478 scopus 로고    scopus 로고
    • Natural killer cells act as rheostats modulating antiviral T cells
    • Waggoner, S. N., M. Cornberg, L. K. Selin, and R. M. Welsh. 2012. Natural killer cells act as rheostats modulating antiviral T cells. Nature 481: 394-398.
    • (2012) Nature , vol.481 , pp. 394-398
    • Waggoner, S.N.1    Cornberg, M.2    Selin, L.K.3    Welsh, R.M.4
  • 36
    • 17544398702 scopus 로고    scopus 로고
    • Biochemical mechanisms of IL-2-regulated Fas-mediated T cell apoptosis
    • Refaeli, Y., L. Van Parijs, C. A. London, J. Tschopp, and A. K. Abbas. 1998. Biochemical mechanisms of IL-2-regulated Fas-mediated T cell apoptosis. Immunity 8: 615-623.
    • (1998) Immunity , vol.8 , pp. 615-623
    • Refaeli, Y.1    Van Parijs, L.2    London, C.A.3    Tschopp, J.4    Abbas, A.K.5
  • 39
    • 84887163293 scopus 로고    scopus 로고
    • Gamma interferon regulates contraction of the influenza virus-specific CD8 T cell response and limits the size of the memory population
    • Prabhu, N., A. W. Ho, K. H. Wong, P. E. Hutchinson, Y. L. Chua, M. Kandasamy, D. C. Lee, B. Sivasankar, and D. M. Kemeny. 2013. Gamma interferon regulates contraction of the influenza virus-specific CD8 T cell response and limits the size of the memory population. J. Virol. 87: 12510-12522.
    • (2013) J. Virol , vol.87 , pp. 12510-12522
    • Prabhu, N.1    Ho, A.W.2    Wong, K.H.3    Hutchinson, P.E.4    Chua, Y.L.5    Kandasamy, M.6    Lee, D.C.7    Sivasankar, B.8    Kemeny, D.M.9
  • 40
    • 38849186081 scopus 로고    scopus 로고
    • CCL2 inhibits the apoptosis program induced by growth factor deprivation, rescuing functional T cells
    • Diaz-Guerra, E., R. Vernal, M. J. del Prete, A. Silva, and J. A. Garcia-Sanz. 2007. CCL2 inhibits the apoptosis program induced by growth factor deprivation, rescuing functional T cells. J. Immunol. 179: 7352-7357.
    • (2007) J. Immunol , vol.179 , pp. 7352-7357
    • Diaz-Guerra, E.1    Vernal, R.2    Del Prete, M.J.3    Silva, A.4    Garcia-Sanz, J.A.5
  • 41
    • 78650737758 scopus 로고    scopus 로고
    • Mature natural killer cells with phenotypic and functional alterations accumulate upon sustained stimulation with IL-15/IL-15Ralpha complexes
    • Elpek, K. G., M. P. Rubinstein, A. Bellemare-Pelletier, A. W. Goldrath, and S. J. Turley. 2010. Mature natural killer cells with phenotypic and functional alterations accumulate upon sustained stimulation with IL-15/IL-15Ralpha complexes. Proc. Natl. Acad. Sci. USA 107: 21647-21652.
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 21647-21652
    • Elpek, K.G.1    Rubinstein, M.P.2    Bellemare-Pelletier, A.3    Goldrath, A.W.4    Turley, S.J.5
  • 42
    • 79956077563 scopus 로고    scopus 로고
    • T cell exhaustion
    • Wherry, E. J. 2011. T cell exhaustion. Nat. Immunol. 12: 492-499.
    • (2011) Nat. Immunol , vol.12 , pp. 492-499
    • Wherry, E.J.1
  • 44
    • 0037322642 scopus 로고    scopus 로고
    • Functional interactions between dendritic cells and NK cells during viral infection
    • Andrews, D. M., A. A. Scalzo, W. M. Yokoyama, M. J. Smyth, and M. A. Degli-Esposti. 2003. Functional interactions between dendritic cells and NK cells during viral infection. Nat. Immunol. 4: 175-181.
    • (2003) Nat. Immunol , vol.4 , pp. 175-181
    • Andrews, D.M.1    Scalzo, A.A.2    Yokoyama, W.M.3    Smyth, M.J.4    Degli-Esposti, M.A.5
  • 45
    • 0037017379 scopus 로고    scopus 로고
    • Contactdependent stimulation and inhibition of dendritic cells by natural killer cells
    • Piccioli, D., S. Sbrana, E. Melandri, and N. M. Valiante. 2002. Contactdependent stimulation and inhibition of dendritic cells by natural killer cells. J. Exp. Med. 195: 335-341.
    • (2002) J. Exp. Med , vol.195 , pp. 335-341
    • Piccioli, D.1    Sbrana, S.2    Melandri, E.3    Valiante, N.M.4
  • 46
    • 0038205944 scopus 로고    scopus 로고
    • NK cells regulate CD4 responses prior to antigen encounter
    • Dowdell, K. C., D. J. Cua, E. Kirkman, and S. A. Stohlman. 2003. NK cells regulate CD4 responses prior to antigen encounter. J. Immunol. 171: 234-239.
    • (2003) J. Immunol , vol.171 , pp. 234-239
    • Dowdell, K.C.1    Cua, D.J.2    Kirkman, E.3    Stohlman, S.A.4
  • 47
    • 33749027763 scopus 로고    scopus 로고
    • Reciprocal regulation between natural killer cells and autoreactive T cells
    • Shi, F. D., and L. Van Kaer. 2006. Reciprocal regulation between natural killer cells and autoreactive T cells. Nat. Rev. Immunol. 6: 751-760.
    • (2006) Nat. Rev. Immunol , vol.6 , pp. 751-760
    • Shi, F.D.1    Van Kaer, L.2
  • 48
    • 0024342935 scopus 로고
    • Role of natural killer cells as immune effectors in encephalitis and demyelination induced by Theiler's virus
    • Paya, C. V., A. K. Patick, P. J. Leibson, and M. Rodriguez. 1989. Role of natural killer cells as immune effectors in encephalitis and demyelination induced by Theiler's virus. J. Immunol. 143: 95-102.
    • (1989) J. Immunol , vol.143 , pp. 95-102
    • Paya, C.V.1    Patick, A.K.2    Leibson, P.J.3    Rodriguez, M.4
  • 49
    • 34248206736 scopus 로고    scopus 로고
    • NK cells negatively regulate antigen presentation and tumor-specific CTLs in a syngeneic lymphoma model
    • Barber, M. A., T. Zhang, B. A. Gagne, and C. L. Sentman. 2007. NK cells negatively regulate antigen presentation and tumor-specific CTLs in a syngeneic lymphoma model. J. Immunol. 178: 6140-6147.
    • (2007) J. Immunol , vol.178 , pp. 6140-6147
    • Barber, M.A.1    Zhang, T.2    Gagne, B.A.3    Sentman, C.L.4
  • 50
    • 0034286992 scopus 로고    scopus 로고
    • In vivo acute depletion of CD8(+) T cells before murine cytomegalovirus infection upregulated innate antiviral activity of natural killer cells
    • Salem, M. L., and M. S. Hossain. 2000. In vivo acute depletion of CD8(+) T cells before murine cytomegalovirus infection upregulated innate antiviral activity of natural killer cells. Int. J. Immunopharmacol. 22: 707-718.
    • (2000) Int. J. Immunopharmacol , vol.22 , pp. 707-718
    • Salem, M.L.1    Hossain, M.S.2
  • 51
    • 79955974536 scopus 로고    scopus 로고
    • DNAM-1 ligand expression on Ag-stimulated T lymphocytes is mediated by ROS-dependent activation of DNA-damage response: Relevance for NK-T cell interaction
    • Ardolino, M., A. Zingoni, C. Cerboni, F. Cecere, A. Soriani, M. L. Iannitto, and A. Santoni. 2011. DNAM-1 ligand expression on Ag-stimulated T lymphocytes is mediated by ROS-dependent activation of DNA-damage response: relevance for NK-T cell interaction. Blood 117: 4778-4786.
    • (2011) Blood , vol.117 , pp. 4778-4786
    • Ardolino, M.1    Zingoni, A.2    Cerboni, C.3    Cecere, F.4    Soriani, A.5    Iannitto, M.L.6    Santoni, A.7
  • 52
    • 84874968418 scopus 로고    scopus 로고
    • Alloreactive CD8 T cells rescued from apoptosis during co-stimulation blockade by Toll-like receptor stimulation remain susceptible to Fas-induced cell death
    • Priyadharshini, B., T. B. Thornley, K. A. Daniels, A. Cuthbert, R. M. Welsh, D. L. Greiner, and M. A. Brehm. 2013. Alloreactive CD8 T cells rescued from apoptosis during co-stimulation blockade by Toll-like receptor stimulation remain susceptible to Fas-induced cell death. Immunology 138: 322-332.
    • (2013) Immunology , vol.138 , pp. 322-332
    • Priyadharshini, B.1    Thornley, T.B.2    Daniels, K.A.3    Cuthbert, A.4    Welsh, R.M.5    Greiner, D.L.6    Brehm, M.A.7
  • 53
    • 0036231207 scopus 로고    scopus 로고
    • Immune privilege and FasL: Two ways to inactivate effector cytotoxic T lymphocytes by FasL-expressing cells
    • Li, J. H., D. Rosen, P. Sondel, and G. Berke. 2002. Immune privilege and FasL: two ways to inactivate effector cytotoxic T lymphocytes by FasL-expressing cells. Immunology 105: 267-277.
    • (2002) Immunology , vol.105 , pp. 267-277
    • Li, J.H.1    Rosen, D.2    Sondel, P.3    Berke, G.4
  • 54
    • 54049139577 scopus 로고    scopus 로고
    • IFN-gamma-dependent recruitment of mature CD27(high) NK cells to lymph nodes primed by dendritic cells
    • Watt, S. V., D. M. Andrews, K. Takeda, M. J. Smyth, and Y. Hayakawa. 2008. IFN-gamma-dependent recruitment of mature CD27(high) NK cells to lymph nodes primed by dendritic cells. J. Immunol. 181: 5323-5330.
    • (2008) J. Immunol , vol.181 , pp. 5323-5330
    • Watt, S.V.1    Andrews, D.M.2    Takeda, K.3    Smyth, M.J.4    Hayakawa, Y.5


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