Hypertrophic chondrocytes in the rabbit growth plate can proliferate and differentiate into osteogenic cells when capillary invasion is interposed by a membrane filter

PLoS ONE

Volumn 9, Issue 8, 2014, Pages

  Enishi, Tetsuya ^a   Yukata, Kiminori ^a   Takahashi, Mitsuhiko ^a   Sato, Ryosuke ^a   Sairyo, Koichi ^a   Yasui, Natsuo ^a  

^a UNIVERSITY OF TOKUSHIMA   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; COLLAGEN TYPE 1; OSTEOCALCIN; OSTEONECTIN;

ANGIOGENESIS; ANIMAL; BONE; BONE DEVELOPMENT; CAPILLARY; CARTILAGE; CARTILAGE CELL; CELL DIFFERENTIATION; CELL PROLIFERATION; CHONDROGENESIS; GROWTH PLATE; HYPERTROPHY; MALE; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; RABBIT;

ANIMALS; BONE AND BONES; CAPILLARIES; CARTILAGE; CASPASE 3; CELL DIFFERENTIATION; CELL PROLIFERATION; CHONDROCYTES; CHONDROGENESIS; COLLAGEN TYPE I; GROWTH PLATE; HYPERTROPHY; MALE; NEOVASCULARIZATION, PHYSIOLOGIC; OSTEOCALCIN; OSTEOGENESIS; OSTEONECTIN; RABBITS;

EID: 84905987355     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0104638     Document Type: Article

References (39)

1. Erlebacher A, Filvaroff EH, Gitelman SE, Derynck R (1995) Toward a molecular understanding of skeletal development. Cell 80: 371-378.
2. Tsumaki N, Yoshikawa H (2005) The role of bone morphogenetic proteins in endochondral bone formation. Cytokine & growth factor reviews 16: 279-285. (Pubitemid 40910317)
3. Olsen BR, Reginato AM, Wang WF (2000) Bone development. Annual Review of Cell and Developmental Biology 16: 191-220. (Pubitemid 32037505)
4. Kronenberg HM (2003) Developmental regulation of the growth plate. Nature 423: 332-336.
5. Yeung Tsang K, Wa Tsang S, Chan D, Cheah KS (2014) The chondrocytic journey in endochondral bone growth and skeletal dysplasia. Birth defects research Part C, Embryo today: reviews 102: 52-73.
6. Brighton CT, Sugioka Y, Hunt RM (1973) Cytoplasmic structures of epiphyseal plate chondrocytes. Quantitative evaluation using electron micrographs of rat costochondral junctions with special reference to the fate of hypertrophic cells. The Journal of bone and joint surgery American volume 55: 771-784.
7. Gibson G, Kohler W, Schaffler M (1995) Chondrocyte apoptosis in endochondral ossification of chick sterna. Dev Dyn 203: 468-476.
8. Shapiro IM, Adams CS, Freeman T, Srinivas V (2005) Fate of the hypertrophic chondrocyte: microenvironmental perspectives on apoptosis and survival in the epiphyseal growth plate. Birth defects research Part C, Embryo today: reviews 75: 330-339.
9. Gibson G, Lin D, Roque M (1997) Apoptosis of terminally differentiated chondrocytes in culture. Exp Cell Res 233: 372-382. (Pubitemid 27252017)
10. Roach H, Shearer J (1989) Cartilage resorption and endochondral bone formation during the development of long bones in chick embryos. Bone Miner 6: 289-309. (Pubitemid 19169332)
11. Holtrop ME (1972) The ultrastructure of the epiphyseal plate. II. The hypertrophic chondrocyte. Calcified tissue research 9: 140-151.
12. Galotto M, Campanile G, Robino G, Cancedda FD, Bianco P, et al. (1994) Hypertrophic chondrocytes undergo further differentiation to osteoblast-like cells and participate in the initial bone formation in developing chick embryo. Journal of bone and mineral research: the official journal of the American Society for Bone and Mineral Research 9: 1239-1249.
13. Descalzi Cancedda F, Gentili C, Manduca P, Cancedda R (1992) Hypertrophic chondrocytes undergo further differentiation in culture. The Journal of cell biology 117: 427-435.
14. Roach HI (1997) New aspects of endochondral ossification in the chick: chondrocyte apoptosis, bone formation by former chondrocytes, and acid phosphatase activity in the endochondral bone matrix. Journal of bone and mineral research: the official journal of the American Society for Bone and Mineral Research 12: 795-805.
15. Bianco P, Cancedda FD, Riminucci M, Cancedda R (1998) Bone formation via cartilage models: the "borderline" chondrocyte. Matrix biology: journal of the International Society for Matrix Biology 17: 185-192.
16. Roach H (1992) Trans-differentiation of hypertrophic chondrocytes into cells capable of producing a mineralized bone matrix. Bone Miner 19: 1-20.
17. Wlodarski KH, Wlodarski PK, Brodzikowska A (2006) Metaplasia of chondrocytes into osteoblasts. Folia Biologica-Krakow 54: 75-80. (Pubitemid 44545234)
18. Higashino K, Sairyo K, Sakamaki T, Komatsubara S, Yukata K, et al. (2007) Vertebral rounding deformity in pediatric spondylolisthesis occurs due to deficient of endochondral ossification of the growth plate: radiological, histological and immunohistochemical analysis of a rat spondylolisthesis model. Spine 32: 2839-2845. (Pubitemid 351339354)
19. Beresford WA (1981) Chondroid bone, secondary cartilage, and metaplasia. Baltimore, Md.: Urban & Schwarzenberg. xvii, 454 p. p.
20. Roach H, Clarke N (2000) Physiological cell death of chondrocytes in vivo is not confined to apoptosis. New observations on the mammalian growth plate. J Bone Joint Surg Br 82: 601-613. (Pubitemid 30312832)
21. Gibson G (1998) Active role of chondrocyte apoptosis in endochondral ossification. Microscopy research and technique 43: 191-204.
22. Kahn A, Simmons D (1977) Chondrocyte-to-osteocyte transformation in grafts of perichondrium-free epiphyseal cartilage. Clin Orthop Relat Res: 299-304. (Pubitemid 8295565)
23. Shimomura Y, Yoneda T, Suzuki F (1975) Osteogenesis by chondrocytes from growth cartilage of rat rib. Calcified tissue research 19: 179-187.
24. Bahney CS, Hu DP, Taylor AJ, Ferro F, Britz HM, et al. (2013) Stem Cell Derived Endochondral Cartilage Stimulates Bone Healing by Tissue Transformation. Journal of bone and mineral research: the official journal of the American Society for Bone and Mineral Research.
25. Yasui N, Sato M, Ochi T, Kimura T, Kawahata H, et al. (1997) Three modes of ossification during distraction osteogenesis in the rat. J Bone Joint Surg Br 79: 824-830. (Pubitemid 27434508)
26. Bruckner P, Horler I, Mendler M, Houze Y, Winterhalter KH, et al. (1989) Induction and prevention of chondrocyte hypertrophy in culture. The Journal of cell biology 109: 2537-2545. (Pubitemid 19282637)
27. Roach HI, Erenpreisa J, Aigner T (1995) Osteogenic differentiation of hypertrophic chondrocytes involves asymmetric cell divisions and apoptosis. The Journal of cell biology 131: 483-494.
28. Roach H, Erenpreisa J (1996) The phenotypic switch from chondrocytes to bone-forming cells involves asymmetric cell division and apoptosis. Connect Tissue Res 35: 85-91. (Pubitemid 27118840)
29. Hayman AR, Jones SJ, Boyde A, Foster D, Colledge WH, et al. (1996) Mice lacking tartrate-resistant acid phosphatase (Acp 5) have disrupted endochondral ossification and mild osteopetrosis. Development 122: 3151-3162. (Pubitemid 26371980)
30. Nordahl J, Andersson G, Reinholt FP (1998) Chondroclasts and osteoclasts in bones of young rats: comparison of ultrastructural and functional features. Calcified tissue international 63: 401-408. (Pubitemid 28476330)
31. Kronenberg HM (2007) The role of the perichondrium in fetal bone development. Annals of the New York Academy of Sciences 1116: 59-64.
32. Maes C, Kobayashi T, Selig MK, Torrekens S, Roth SI, et al. (2010) Osteoblast precursors, but not mature osteoblasts, move into developing and fractured bones along with invading blood vessels. Developmental cell 19: 329-344.
33. Maye P, Fu Y, Butler DL, Chokalingam K, Liu Y, et al. (2011) Generation and characterization of Col10a1-mcherry reporter mice. Genesis 49: 410-418.
34. Kretzschmar K, Watt FM (2012) Lineage tracing. Cell 148: 33-45.
35. Eguchi G, Kodama R (1993) Transdifferentiation. Curr Opin Cell Biol 5: 1023-1028. (Pubitemid 23340510)
36. Salter R, Harris W (1963) Injuries Involving the Epiphyseal Plate. J Bone Joint Surg Am 45: 587-622.
37. Chung R, Foster BK, Xian CJ (2011) Injury responses and repair mechanisms of the injured growth plate. Frontiers in bioscience 3: 117-125.
38. Musumeci G, Castrogiovanni P, Loreto C, Castorina S, Pichler K, et al. (2013) Post-traumatic caspase-3 expression in the adjacent areas of growth plate injury site: a morphological study. International journal of molecular sciences 14: 15767-15784.
39. Wattenbarger JM, Gruber HE, Phieffer LS (2002) Physeal fractures, part I: histologic features of bone, cartilage, and bar formation in a small animal model. Journal of pediatric orthopedics 22: 703-709. (Pubitemid 35215935)