Aberrant DNA hypermethylation of SDHC: A novel mechanism of tumor development in Carney triad

Endocrine-Related Cancer

Volumn 21, Issue 4, 2014, Pages 567-577

  Haller, Florian ^a   Moskalev, Evgeny A ^a   Faucz, Fabio R ^b   Barthelmeß, Sarah ^a   Wiemann, Stefan ^c   Bieg, Matthias ^c   Assie, Guillaume ^d,e   Bertherat, Jerome ^d,e   Schaefer, Inga Marie ^f,k   Otto, Claudia ^g   Rattenberry, Eleanor ^h   Maher, Eamonn R ^h,i   Ströbel, Philipp ^f   Werner, Martin ^g   Carney, J Aidan ^j   Hartmann, Arndt ^a   Stratakis, Constantine A ^b   Agaimy, Abbas ^a  

^a UNIVERSITY HOSPITAL ERLANGEN   (Germany)

^b EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^c GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^d INSTITUT COCHIN   (France)

^e Institut Cochin CNRS UMR 8104 Université Paris Descartes ^*  (France)

^f UNIVERSITY OF GÖTTINGEN   (Germany)

^g UNIVERSITY OF FREIBURG   (Germany)

^h UNIVERSITY OF BIRMINGHAM   (United Kingdom)

ⁱ UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^j MAYO CLINIC   (United States)

^k BRIGHAM AND WOMEN S HOSPITAL   (United States)

more..

Author keywords

Carney triad; GIST; Paraganglioma; SDH complex; SDHC

Indexed keywords

MESSENGER RNA; STEM CELL FACTOR RECEPTOR; SUCCINATE DEHYDROGENASE; SUCCINATE DEHYDROGENASE (UBIQUINONE); SUCCINATE DEHYDROGENASE COMPLEX SUBUNIT A; SUCCINATE DEHYDROGENASE COMPLEX SUBUNIT C; UNCLASSIFIED DRUG; MEMBRANE PROTEIN; SDHC PROTEIN, HUMAN;

ADOLESCENT; ADULT; AGED; ARTICLE; CARCINOGENESIS; CARNEY COMPLEX; CARNEY STRATAKIS SYNDROME; CHONDROMA; CLINICAL ARTICLE; CONTROLLED STUDY; CPG ISLAND; DNA METHYLATION; ENZYME ACTIVITY; EPIGENETICS; FAMILIAL DISEASE; FEMALE; GASTROINTESTINAL STROMAL TUMOR; GENE INACTIVATION; GENE LOCUS; GENE MUTATION; HUMAN; LUNG HAMARTOMA; MALE; PARAGANGLIOMA; PARALLEL BISULFITE SEQUENCING; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; RARE DISEASE; RECEPTOR DOWN REGULATION; SEQUENCE ANALYSIS; STOMACH MUCOSA; VERY ELDERLY; CASE REPORT; CHEMODECTOMA; DOWN REGULATION; GENETIC EPIGENESIS; GENETICS; LEIOMYOSARCOMA; LUNG TUMOR; METABOLISM; MIDDLE AGED; MUTATION; STOMACH TUMOR; YOUNG ADULT;

ADOLESCENT; ADULT; CHONDROMA; CPG ISLANDS; DNA METHYLATION; DOWN-REGULATION; EPIGENESIS, GENETIC; FEMALE; HUMANS; LEIOMYOSARCOMA; LUNG NEOPLASMS; MEMBRANE PROTEINS; MIDDLE AGED; MUTATION; PARAGANGLIOMA, EXTRA-ADRENAL; STOMACH NEOPLASMS; YOUNG ADULT;

EID: 84905973034     PISSN: 13510088     EISSN: 14796821     Source Type: Journal    
DOI: 10.1530/ERC-14-0254     Document Type: Article

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