Beyond paraquats: Dialkyl 3,3′- and 3,4′-bipyridinium amphiphiles as antibacterial agents

Bioorganic and Medicinal Chemistry Letters

Volumn 24, Issue 16, 2014, Pages 3706-3709

  Ator, Laura E ^a   Jennings, Megan C ^b   McGettigan, Amanda R ^a   Paul, Jared J ^a   Wuest, William M ^b   Minbiole, Kevin P C ^a  

^a VILLANOVA UNIVERSITY   (United States)

^b Temple University   (United States)

Author keywords

Amphiphile; Antibacterial; Bipyridinium; Metaquat; Paraquat

Indexed keywords

ANTIINFECTIVE AGENT; PYRIDINIUM DERIVATIVE; DIALKYL 3,3' BIPYRIDINIUM; DIALKYL 3,4' BIPYRIDINIUM; PARAQUAT; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

CHEMICAL STRUCTURE; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; ENTEROCOCCUS FAECALIS; ESCHERICHIA COLI; GROWTH, DEVELOPMENT AND AGING; MICROBIAL SENSITIVITY TEST; PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS AUREUS; STRUCTURE ACTIVITY RELATION; SYNTHESIS; ANTIBACTERIAL ACTIVITY; ARTICLE; DRUG STRUCTURE; ELECTROCHEMISTRY; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; OXIDATION REDUCTION REACTION;

ANTI-BACTERIAL AGENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENTEROCOCCUS FAECALIS; ESCHERICHIA COLI; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; PSEUDOMONAS AERUGINOSA; PYRIDINIUM COMPOUNDS; STAPHYLOCOCCUS AUREUS; STRUCTURE-ACTIVITY RELATIONSHIP;

BACTERIA (MICROORGANISMS); NEGIBACTERIA; POSIBACTERIA;

EID: 84905906292     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2014.07.024     Document Type: Article

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