메뉴 건너뛰기




Volumn 16, Issue 10, 2014, Pages 1-7

Obstructive Sleep Apnea and Acute Coronary Syndromes: Etiology, Risk, and Management

Author keywords

Acute coronary syndrome (ACS); Coronary artery disease (CAD); Obstructive sleep apnea (OSA); Risk factor

Indexed keywords

ACUTE CORONARY SYNDROME; COMPLICATION; CORONARY DISEASE; HUMAN; PREVALENCE; RISK FACTOR; SLEEP APNEA, OBSTRUCTIVE;

EID: 84905889079     PISSN: 15233782     EISSN: 15343170     Source Type: Journal    
DOI: 10.1007/s11886-014-0535-y     Document Type: Review
Times cited : (26)

References (43)
  • 1
    • 48949085757 scopus 로고    scopus 로고
    • Sleep apnea and cardiovascular disease: an American Heart Association/American College of Cardiology Foundation Scientific Statement from the American Heart Association Council for High Blood Pressure Research Professional Education Committee, Council on Clinical Cardiology, Stroke Council, and Council on Cardiovascular Nursing
    • PID: 18702977
    • Somers VK, White DP, Amin R, et al. Sleep apnea and cardiovascular disease: an American Heart Association/American College of Cardiology Foundation Scientific Statement from the American Heart Association Council for High Blood Pressure Research Professional Education Committee, Council on Clinical Cardiology, Stroke Council, and Council on Cardiovascular Nursing. J Am Coll Cardiol. 2008;52:686–717.
    • (2008) J Am Coll Cardiol , vol.52 , pp. 686-717
    • Somers, V.K.1    White, D.P.2    Amin, R.3
  • 2
    • 0029984389 scopus 로고    scopus 로고
    • Sleep disordered breathing in men with coronary artery disease
    • PID: 8617073, COI: 1:STN:280:DyaK287otFyjsQ%3D%3D
    • Mooe T, Rabben T, Wiklund U, Franklin KA, Eriksson P. Sleep disordered breathing in men with coronary artery disease. Chest. 1996;109:659–63.
    • (1996) Chest , vol.109 , pp. 659-663
    • Mooe, T.1    Rabben, T.2    Wiklund, U.3    Franklin, K.A.4    Eriksson, P.5
  • 3
    • 33751289355 scopus 로고    scopus 로고
    • Increased incidence of coronary artery disease in sleep apnoea: a long-term follow-up
    • PID: 16641120, COI: 1:STN:280:DC%2BD28rit1WrtQ%3D%3D
    • Peker Y, Carlson J, Hedner J. Increased incidence of coronary artery disease in sleep apnoea: a long-term follow-up. Eur Respir J. 2006;28:596–602.
    • (2006) Eur Respir J , vol.28 , pp. 596-602
    • Peker, Y.1    Carlson, J.2    Hedner, J.3
  • 4
    • 33845715699 scopus 로고    scopus 로고
    • Impact of obstructive sleep apnea on clinical and angiographic outcomes following percutaneous coronary intervention in patients with acute coronary syndrome
    • PID: 17196456
    • Yumino D, Tsurumi Y, Takagi A, Suzuki K, Kasanuki H. Impact of obstructive sleep apnea on clinical and angiographic outcomes following percutaneous coronary intervention in patients with acute coronary syndrome. Am J Cardiol. 2007;99:26–30.
    • (2007) Am J Cardiol , vol.99 , pp. 26-30
    • Yumino, D.1    Tsurumi, Y.2    Takagi, A.3    Suzuki, K.4    Kasanuki, H.5
  • 5
    • 84879112093 scopus 로고    scopus 로고
    • Association between obesity and infarct size: insight into the obesity paradox
    • PID: 23102600
    • Cepeda-Valery B, Slipczuk L, Figueredo VM, et al. Association between obesity and infarct size: insight into the obesity paradox. Int J Cardiol. 2013;167:604–6.
    • (2013) Int J Cardiol , vol.167 , pp. 604-606
    • Cepeda-Valery, B.1    Slipczuk, L.2    Figueredo, V.M.3
  • 6
    • 77954761677 scopus 로고    scopus 로고
    • Obstructive sleep apnea as a risk factor for coronary events or cardiovascular death
    • PID: 19777281, This study found that OSA was an independent risk factor for cardiovascular events, including myocardial infarction
    • Shah NA, Yaggi HK, Concato J, Mohsenin V. Obstructive sleep apnea as a risk factor for coronary events or cardiovascular death. Sleep Breath. 2010;14:131–6. This study found that OSA was an independent risk factor for cardiovascular events, including myocardial infarction.
    • (2010) Sleep Breath , vol.14 , pp. 131-136
    • Shah, N.A.1    Yaggi, H.K.2    Concato, J.3    Mohsenin, V.4
  • 7
    • 17544390734 scopus 로고    scopus 로고
    • Obstructive sleep apnea as a risk marker in coronary artery disease
    • PID: 10702648, COI: 1:STN:280:DC%2BD3c7mvFWitA%3D%3D
    • Schafer H, Koehler U, Ewig S, et al. Obstructive sleep apnea as a risk marker in coronary artery disease. Cardiology. 1999;92:79–89.
    • (1999) Cardiology , vol.92 , pp. 79-89
    • Schafer, H.1    Koehler, U.2    Ewig, S.3
  • 8
    • 0035148723 scopus 로고    scopus 로고
    • Sleep-disordered breathing and cardiovascular disease: cross-sectional results of the Sleep Heart Health Study
    • PID: 11208620, COI: 1:STN:280:DC%2BD3MzgtVygsw%3D%3D
    • Shahar E, Whitney C, Redline S, et al. Sleep-disordered breathing and cardiovascular disease: cross-sectional results of the Sleep Heart Health Study. Am J Respir Crit Care Med. 2001;163:19–25.
    • (2001) Am J Respir Crit Care Med , vol.163 , pp. 19-25
    • Shahar, E.1    Whitney, C.2    Redline, S.3
  • 9
    • 77955171749 scopus 로고    scopus 로고
    • Prospective study of obstructive sleep apnea and incident coronary heart disease and heart failure: the Sleep Heart Health Study
    • PID: 20625114, This study is the 8-year follow-up of the Sleep Heart Health Study, a large population based study of patients free of coronary artery disease, and showed that OSA was a significant predictor of incident coronary artery disease, myocardial infarction, revascularization procedure, or cardiovascular death
    • Gottlieb DJ, Yenokyan G, Newman AB, et al. Prospective study of obstructive sleep apnea and incident coronary heart disease and heart failure: the Sleep Heart Health Study. Circulation. 2010;122:352–60. This study is the 8-year follow-up of the Sleep Heart Health Study, a large population based study of patients free of coronary artery disease, and showed that OSA was a significant predictor of incident coronary artery disease, myocardial infarction, revascularization procedure, or cardiovascular death.
    • (2010) Circulation , vol.122 , pp. 352-360
    • Gottlieb, D.J.1    Yenokyan, G.2    Newman, A.B.3
  • 10
    • 0035891601 scopus 로고    scopus 로고
    • Sleep disordered breathing and coronary artery disease: long-term prognosis
    • PID: 11734445, COI: 1:STN:280:DC%2BD3Mnosl2kuw%3D%3D
    • Mooe T, Franklin KA, Holmström K, Rabben T, Wiklund U. Sleep disordered breathing and coronary artery disease: long-term prognosis. Am J Respir Crit Care Med. 2001;164:1910–3.
    • (2001) Am J Respir Crit Care Med , vol.164 , pp. 1910-1913
    • Mooe, T.1    Franklin, K.A.2    Holmström, K.3    Rabben, T.4    Wiklund, U.5
  • 11
    • 84885111728 scopus 로고    scopus 로고
    • Clinical characteristics of patients with acute coronary syndrome at high clinical suspicion for obstructive sleep apnea syndrome
    • Szymanski FM, Filipiak KJ, Hrynkiewicz-Szymanska A, et al. Clinical characteristics of patients with acute coronary syndrome at high clinical suspicion for obstructive sleep apnea syndrome. Hell J Cardiol. 2013;54:348–55.
    • (2013) Hell J Cardiol , vol.54 , pp. 348-355
    • Szymanski, F.M.1    Filipiak, K.J.2    Hrynkiewicz-Szymanska, A.3
  • 12
    • 77955889788 scopus 로고    scopus 로고
    • Under-diagnosis of sleep apnea in patients after acute myocardial infarction
    • PID: 20723806
    • Konecny T, Sert Kuniyoshi F, Orban M, et al. Under-diagnosis of sleep apnea in patients after acute myocardial infarction. J Am Coll Cardiol. 2010;56(9):742–3.
    • (2010) J Am Coll Cardiol , vol.56 , Issue.9 , pp. 742-743
    • Konecny, T.1    Sert Kuniyoshi, F.2    Orban, M.3
  • 13
    • 0029977318 scopus 로고    scopus 로고
    • Attenuated endothelium dependent vascular relaxation in patients with sleep apnea
    • PID: 8762200, COI: 1:STN:280:DyaK28zlvVSlsQ%3D%3D
    • Carlson JT, Rangemark C, Hedner JA. Attenuated endothelium dependent vascular relaxation in patients with sleep apnea. J Hypertens. 1996;14:577–84.
    • (1996) J Hypertens , vol.14 , pp. 577-584
    • Carlson, J.T.1    Rangemark, C.2    Hedner, J.A.3
  • 14
    • 0034890640 scopus 로고    scopus 로고
    • Hemodynamic effects of simulated obstructive apneas in humans with and without heart failure
    • PID: 11399711, COI: 1:STN:280:DC%2BD3Mzks1Kjtg%3D%3D
    • Bradley TD, Hall MJ, Ando S, Floras JS. Hemodynamic effects of simulated obstructive apneas in humans with and without heart failure. Chest. 2001;119:1827–35.
    • (2001) Chest , vol.119 , pp. 1827-1835
    • Bradley, T.D.1    Hall, M.J.2    Ando, S.3    Floras, J.S.4
  • 15
    • 62549144847 scopus 로고    scopus 로고
    • Obstructive sleep apnea leads to transient uncoupling of coronary blood flow and myocardial work in humans
    • PID: 19238814
    • Hamilton GS, Meredith IT, Walker AM, Solin P. Obstructive sleep apnea leads to transient uncoupling of coronary blood flow and myocardial work in humans. Sleep. 2009;32:263–70.
    • (2009) Sleep , vol.32 , pp. 263-270
    • Hamilton, G.S.1    Meredith, I.T.2    Walker, A.M.3    Solin, P.4
  • 16
    • 23944511645 scopus 로고    scopus 로고
    • Altered blood rheology in obstructive sleep apnea as a mediator of cardiovascular risk
    • PID: 16015032
    • Steiner S, Jax T, Evers S, Hennersdorf M, Schwalen A, Strauer BE. Altered blood rheology in obstructive sleep apnea as a mediator of cardiovascular risk. Cardiology. 2005;104:92–6.
    • (2005) Cardiology , vol.104 , pp. 92-96
    • Steiner, S.1    Jax, T.2    Evers, S.3    Hennersdorf, M.4    Schwalen, A.5    Strauer, B.E.6
  • 18
  • 19
    • 24144502902 scopus 로고    scopus 로고
    • Increased carotid intima-media thickness and serum inflammatory markers in obstructive sleep apnea
    • PID: 16120716
    • Minoguchi K, Yokoe T, Tazaki T, et al. Increased carotid intima-media thickness and serum inflammatory markers in obstructive sleep apnea. Am J Respir Crit Care Med. 2005;172:625–30.
    • (2005) Am J Respir Crit Care Med , vol.172 , pp. 625-630
    • Minoguchi, K.1    Yokoe, T.2    Tazaki, T.3
  • 20
    • 28144434536 scopus 로고    scopus 로고
    • The severity of oxygen desaturation is predictive of carotid wall thickening and plaque occurrence
    • PID: 16304292
    • Baguet JP, Hammer L, Levy P, et al. The severity of oxygen desaturation is predictive of carotid wall thickening and plaque occurrence. Chest. 2005;128:3407–12.
    • (2005) Chest , vol.128 , pp. 3407-3412
    • Baguet, J.P.1    Hammer, L.2    Levy, P.3
  • 21
    • 42149171750 scopus 로고    scopus 로고
    • Independent association between obstructive sleep apnea and subclinical coronary artery disease
    • PID: 18263678
    • Sorajja D, Gami AS, Somers VK, et al. Independent association between obstructive sleep apnea and subclinical coronary artery disease. Chest. 2008;133:927–33.
    • (2008) Chest , vol.133 , pp. 927-933
    • Sorajja, D.1    Gami, A.S.2    Somers, V.K.3
  • 22
    • 84866154235 scopus 로고    scopus 로고
    • Links between sleep disordered breathing, coronary atherosclerotic burden, and cardiac biomarkers in patients with stable coronary artery disease
    • PID: 22525967
    • Inami T, Seino Y, Otsuka T, et al. Links between sleep disordered breathing, coronary atherosclerotic burden, and cardiac biomarkers in patients with stable coronary artery disease. J Cardiol. 2012;60:180–6.
    • (2012) J Cardiol , vol.60 , pp. 180-186
    • Inami, T.1    Seino, Y.2    Otsuka, T.3
  • 23
    • 84893648726 scopus 로고    scopus 로고
    • OSA and coronary plaque characteristics
    • PID: 24178625
    • Tan A, Hau W, Ho HH, et al. OSA and coronary plaque characteristics. Chest. 2014;145:322–30.
    • (2014) Chest , vol.145 , pp. 322-330
    • Tan, A.1    Hau, W.2    Ho, H.H.3
  • 24
    • 84867230873 scopus 로고    scopus 로고
    • Independent association between obstructive sleep apnea and noncalcified coronary plaque demonstrated by noninvasive coronary computed tomography angiography
    • PID: 22949086
    • Sharma S, Gebregziabher M, Parker AT, et al. Independent association between obstructive sleep apnea and noncalcified coronary plaque demonstrated by noninvasive coronary computed tomography angiography. Clin Cardiol. 2012;35:641–5.
    • (2012) Clin Cardiol , vol.35 , pp. 641-645
    • Sharma, S.1    Gebregziabher, M.2    Parker, A.T.3
  • 25
    • 13844315741 scopus 로고    scopus 로고
    • Cardiac rhythm disturbances an ST segment depression episodes in patients with obstructive sleep apnea-hypopnea syndrome and its mechanisms
    • PID: 15653957
    • Alonso-Fernandez A, Garcıa Rıo F, Racionero MA, et al. Cardiac rhythm disturbances an ST segment depression episodes in patients with obstructive sleep apnea-hypopnea syndrome and its mechanisms. Chest. 2005;127:15–22.
    • (2005) Chest , vol.127 , pp. 15-22
    • Alonso-Fernandez, A.1    Garcıa Rıo, F.2    Racionero, M.A.3
  • 26
    • 0034124418 scopus 로고    scopus 로고
    • Sleep-disordered breathing and myocardial ischemia in patients with coronary artery disease
    • PID: 10858389, COI: 1:STN:280:DC%2BD3czhs12ntw%3D%3D
    • Mooe T, Franklin KA, Wiklund U, Rabben T, Holmström K. Sleep-disordered breathing and myocardial ischemia in patients with coronary artery disease. Chest. 2000;117:1597–602.
    • (2000) Chest , vol.117 , pp. 1597-1602
    • Mooe, T.1    Franklin, K.A.2    Wiklund, U.3    Rabben, T.4    Holmström, K.5
  • 27
    • 47349106112 scopus 로고    scopus 로고
    • Day–night variation of acute myocardial infarction in obstructive sleep apnea
    • PID: 18652941
    • Kuniyoshi FH, Garcia-Touchard A, Gami AS, et al. Day–night variation of acute myocardial infarction in obstructive sleep apnea. J Am Coll Cardiol. 2008;52:343–6.
    • (2008) J Am Coll Cardiol , vol.52 , pp. 343-346
    • Kuniyoshi, F.H.1    Garcia-Touchard, A.2    Gami, A.S.3
  • 28
    • 84878011302 scopus 로고    scopus 로고
    • Obstructive sleep apnea and acute myocardial infarction severity: ischemic preconditioning?
    • PID: 23090861, This study found that OSA was associated with smaller infarct size in patients presenting with nonfatal myocardial infarct
    • Shah N, Redline S, Yaggi HK, et al. Obstructive sleep apnea and acute myocardial infarction severity: ischemic preconditioning? Sleep Breath. 2013;17:819–26. This study found that OSA was associated with smaller infarct size in patients presenting with nonfatal myocardial infarct.
    • (2013) Sleep Breath , vol.17 , pp. 819-826
    • Shah, N.1    Redline, S.2    Yaggi, H.K.3
  • 29
    • 77949517064 scopus 로고    scopus 로고
    • Occurrence of coronary collateral vessels in patients with sleep apnea and total coronary occlusion
    • Stephan S, Schueller PO, Schulze VM, Strauer BE. Occurrence of coronary collateral vessels in patients with sleep apnea and total coronary occlusion. Chest. 2010;137:516–20.
    • (2010) Chest , vol.137 , pp. 516-520
    • Stephan, S.1    Schueller, P.O.2    Schulze, V.M.3    Strauer, B.E.4
  • 30
    • 84871968092 scopus 로고    scopus 로고
    • Endothelial progenitor cells in acute myocardial infarction and sleep-disordered breathing
    • PID: 23155141, COI: 1:CAS:528:DC%2BC3sXhvFGisrc%3D
    • Berger S, Aronson D, Lavie P, Lavie L. Endothelial progenitor cells in acute myocardial infarction and sleep-disordered breathing. Am J Respir Crit Care Med. 2013;187:90–8.
    • (2013) Am J Respir Crit Care Med , vol.187 , pp. 90-98
    • Berger, S.1    Aronson, D.2    Lavie, P.3    Lavie, L.4
  • 31
    • 33749021087 scopus 로고    scopus 로고
    • Obstructive sleep apnea inhibits the recovery of left ventricular function in patients with acute myocardial infarction
    • PID: 16956914
    • Nakashima H, Katayama T, Takagi C, et al. Obstructive sleep apnea inhibits the recovery of left ventricular function in patients with acute myocardial infarction. Eur Heart J. 2006;27:2317–22.
    • (2006) Eur Heart J , vol.27 , pp. 2317-2322
    • Nakashima, H.1    Katayama, T.2    Takagi, C.3
  • 32
    • 79960391943 scopus 로고    scopus 로고
    • Patients with obstructive sleep apnea exhibit impaired endothelial function after myocardial infarction
    • PID: 21349927
    • Sert Kuniyoshi FH, Singh P, Gami AS, et al. Patients with obstructive sleep apnea exhibit impaired endothelial function after myocardial infarction. Chest. 2011;140:62–7.
    • (2011) Chest , vol.140 , pp. 62-67
    • Sert Kuniyoshi, F.H.1    Singh, P.2    Gami, A.S.3
  • 33
    • 84862973432 scopus 로고    scopus 로고
    • Severe obstructive sleep apnea and outcomes following myocardial infarction
    • Lee CH, Khoo SM, Chan MY, et al. Severe obstructive sleep apnea and outcomes following myocardial infarction. J Clin Sleep Med. 2011;15(7):616–21.
    • (2011) J Clin Sleep Med , vol.15 , Issue.7 , pp. 616-621
    • Lee, C.H.1    Khoo, S.M.2    Chan, M.Y.3
  • 34
    • 84857598585 scopus 로고    scopus 로고
    • Sleep disordered breathing in patients with acute coronary syndromes
    • Schiza SE, Simantirakis E, Bouloukaki I, et al. Sleep disordered breathing in patients with acute coronary syndromes. J Clin Sleep Med. 2012;15(8):21–6.
    • (2012) J Clin Sleep Med , vol.15 , Issue.8 , pp. 21-26
    • Schiza, S.E.1    Simantirakis, E.2    Bouloukaki, I.3
  • 35
    • 77949526342 scopus 로고    scopus 로고
    • Interactions between obesity and obstructive sleep apnea: implications for treatment
    • PID: 20202954, COI: 1:CAS:528:DC%2BC3cXksVyku7Y%3D
    • Romero-Corral A, Caples SM, Lopez-Jimenez F, Somers VK. Interactions between obesity and obstructive sleep apnea: implications for treatment. Chest. 2010;137:711–9.
    • (2010) Chest , vol.137 , pp. 711-719
    • Romero-Corral, A.1    Caples, S.M.2    Lopez-Jimenez, F.3    Somers, V.K.4
  • 36
    • 15244344823 scopus 로고    scopus 로고
    • Long-term cardiovascular outcomes in men with obstructive sleep apnoea-hypopnoea with or without treatment with continuous positive airway pressure: an observational study
    • PID: 15781100
    • Marin JM, Carrizo SJ, Vicente E, Agusti AG. Long-term cardiovascular outcomes in men with obstructive sleep apnoea-hypopnoea with or without treatment with continuous positive airway pressure: an observational study. Lancet. 2005;365:1046–53.
    • (2005) Lancet , vol.365 , pp. 1046-1053
    • Marin, J.M.1    Carrizo, S.J.2    Vicente, E.3    Agusti, A.G.4
  • 37
    • 2442453389 scopus 로고    scopus 로고
    • Benefits of obstructive sleep apnea treatment in coronary artery disease: a long term follow-up study
    • PID: 15120882
    • Milleron O, Pilliere R, Foucher A, et al. Benefits of obstructive sleep apnea treatment in coronary artery disease: a long term follow-up study. Eur Heart J. 2004;25:728–34.
    • (2004) Eur Heart J , vol.25 , pp. 728-734
    • Milleron, O.1    Pilliere, R.2    Foucher, A.3
  • 38
    • 0028930199 scopus 로고
    • Sleep apnea and nocturnal angina
    • PID: 7715342, COI: 1:STN:280:DyaK2M3jtFWksw%3D%3D
    • Franklin KA, Nilsson JB, Sahlin C, Naslund U. Sleep apnea and nocturnal angina. Lancet. 1995;345:1085–7.
    • (1995) Lancet , vol.345 , pp. 1085-1087
    • Franklin, K.A.1    Nilsson, J.B.2    Sahlin, C.3    Naslund, U.4
  • 39
    • 0033571791 scopus 로고    scopus 로고
    • Nocturnal ischemic events in patients with obstructive sleep apnea syndrome and ischemic heart disease: effects of continuous positive air pressure treatment
    • PID: 10577565, COI: 1:STN:280:DC%2BD3c%2FktlCqtQ%3D%3D
    • Peled N, Abinader EG, Pillar G, Sharif D, Lavie P. Nocturnal ischemic events in patients with obstructive sleep apnea syndrome and ischemic heart disease: effects of continuous positive air pressure treatment. J Am Coll Cardiol. 1999;34:1744–9.
    • (1999) J Am Coll Cardiol , vol.34 , pp. 1744-1749
    • Peled, N.1    Abinader, E.G.2    Pillar, G.3    Sharif, D.4    Lavie, P.5
  • 40
    • 84885320893 scopus 로고    scopus 로고
    • CPAP effect on recurrent episodes in patients with sleep apnea and myocardial infarction
    • Garcia-Rio F, Alonso-Fernandez A, Armada E, et al. CPAP effect on recurrent episodes in patients with sleep apnea and myocardial infarction. Int J Cardiol. 2013;30(168):1328–35.
    • (2013) Int J Cardiol , vol.30 , Issue.168 , pp. 1328-1335
    • Garcia-Rio, F.1    Alonso-Fernandez, A.2    Armada, E.3
  • 41
    • 84939871862 scopus 로고    scopus 로고
    • Obstructive sleep apnea in the acute myocardial infarction setting—should I treat my patient? J Sleep Disor.2013
    • Shah N, Kizer JR, Mohsenin V. Obstructive sleep apnea in the acute myocardial infarction setting—should I treat my patient? J Sleep Disor.2013. Treat Care 2:1.
    • Treat Care , vol.2 , pp. 1
    • Shah, N.1    Kizer, J.R.2    Mohsenin, V.3
  • 42
    • 84883865909 scopus 로고    scopus 로고
    • Rationale and methodology of the impact of continuous positive airway pressure on patients with ACS and nonsleepy OSA: The ISAACC Trial
    • Methodology of the ISAAC trial: Impact of Continuous Positive Airway Pressure on Patients with Acute coronary syndrome and Non-sleepy OSA
    • Esquinas C, Sanchez-de-la Torre M, Aldoma A, et al. Rationale and methodology of the impact of continuous positive airway pressure on patients with ACS and nonsleepy OSA: The ISAACC Trial. Clin Cardiol. 2013;36:495–501. Methodology of the ISAAC trial: Impact of Continuous Positive Airway Pressure on Patients with Acute coronary syndrome and Non-sleepy OSA.
    • (2013) Clin Cardiol , vol.36 , pp. 495-501
    • Esquinas, C.1    Sanchez-de-la Torre, M.2    Aldoma, A.3
  • 43
    • 84861969568 scopus 로고    scopus 로고
    • The sleep apnea cardiovascular endpoints (SAVE) trial: rationale and start-up phase
    • PID: 22263035
    • McEvoy D, Anderson CS, Antic NA, et al. The sleep apnea cardiovascular endpoints (SAVE) trial: rationale and start-up phase. J Thorac Dis. 2010;2(3):138–43.
    • (2010) J Thorac Dis , vol.2 , Issue.3 , pp. 138-143
    • McEvoy, D.1    Anderson, C.S.2    Antic, N.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.