BRAF V600E mutation in two distinct meningeal melanocytomas associated with a nevus of ota

Journal of Clinical Oncology

Volumn 32, Issue 20, 2014, Pages

  Muñoz Hidalgo, Lisandra ^a   Lopez Gines, Concha ^a   Navarro, Lara ^a   Callaghan, Robert C ^a   San Miguel, Teresa ^a   Gil Benso, Rosario ^a   Quilis, Vicent ^b   Botella, Laura ^b   Gonzalez Darder, Jose ^b   Cerda Nicolas, Miguel ^a  

^a UNIVERSITY OF VALENCIA   (Spain)

^b HOSPITAL CLÍNICO UNIVERSITARIO   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

B RAF KINASE; KI 67 ANTIGEN; MELAN A; MONOCLONAL ANTIBODY HMB 45; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN NF2; PROTEIN S 100; UNCLASSIFIED DRUG; VIMENTIN;

ADOLESCENT; AMINO ACID SUBSTITUTION; ARTICLE; CASE REPORT; CELL PROLIFERATION; CYTOPLASM; DURA MATER; EPITHELIOID CELL; EXON; FOLLOW UP; GENE MUTATION; HEADACHE; HISTOPATHOLOGY; HUMAN; IMMUNOHISTOCHEMISTRY; INTRACRANIAL HYPERTENSION; MALE; MELANOCYTOSIS; MELANOSIS; MENINGEAL MELANOCYTOMA; MITOSIS; MULTIPLEX LIGATION DEPENDENT PROBE AMPLIFICATION; NAUSEA AND VOMITING; NEUROIMAGING; NUCLEAR MAGNETIC RESONANCE IMAGING; OTA NEVUS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; SPINDLE CELL; TEMPORAL LOBE; TUMOR VOLUME;

ADOLESCENT; CELL TRANSFORMATION, NEOPLASTIC; GLUTAMIC ACID; HUMANS; MALE; MELANOCYTES; MELANOMA; MENINGEAL NEOPLASMS; MUTATION; NEVUS OF OTA; PROTO-ONCOGENE PROTEINS B-RAF; SIGNAL TRANSDUCTION; SKIN NEOPLASMS; VALINE;

EID: 84905855460     PISSN: 0732183X     EISSN: 15277755     Source Type: Journal    
DOI: 10.1200/JCO.2013.48.8718     Document Type: Article

References (15)

1. Louis DN, Ohgaki H, Wiestler OD (eds), et al: WHO Classification of Tumours of the Central Nervous System (ed 4). Lyon, France, IARC, 2007, pp 181-183
2. Liubinas SV, Maartens N, Drummond KJ: Primary melanocytic neoplasms of the central nervous system. J Clin Neurosci 17:1227-1232, 2010
3. Navas M, Pascual JM, Fraga J, et al: Intracranial intermediate-grade meningeal melanocytoma with increased cellular proliferative index: An illustrative case associated with a nevus of Ota. J Neurooncol 95:105-115, 2009
4. Pan H, Wang H, Fan Y: Intracranial meningeal melanocytoma associated with nevus of Ota. J Clin Neurosci 18:1548-1550, 2011
5. Wang F, Qiao G, Lou X, et al: Malignant transformation of intracranial meningeal melanocytoma: Case report and review of the literature. Neuropathology 31:414-420, 2011
6. Hino K, Nagane M, Fujioka Y, et al: Meningeal melanocytoma associated with ipsilateral nevus of Ota presenting as intracerebral hemorrhage: Case report. Neurosurgery 56:E1376, 2005
7. Adameyko I, Lallemend F: Glial versus melanocyte cell fate choice: Schwann cell precursors as a cellular origin of melanocytes. Cell Mol Life Sci 67:3037-3055, 2010
8. Yazdi AS, Palmedo G, Flaig MJ, et al: Mutations of the BRAF gene in benign and malignant melanocytic lesions. J Invest Dermatol 121:1160-1162, 2003 (Pubitemid 37430987)
9. Vredeveld LC, Possik PA, Smit MA, et al: Abrogation of BRAFV600Einduced senescence by PI3K pathway activation contributes to melanomagenesis. Genes Dev 26:1055-1069, 2012
10. Paraiso KH, Xiang Y, Rebecca VW, et al: PTEN loss confers BRAF inhibitor resistance to melanoma cells through the suppression of BIM expression. Cancer Res 71:2750-2760, 2011
11. Murray LB, Lau YK, Yu Q: Merlin is a negative regulator of human melanoma growth. PLoS One 7:e43295, 2012
12. Evans DG, Huson SM, Donnai D, et al: A clinical study of type 2 neurofibromatosis. Q J Med 84:603-618, 1992 (Pubitemid 23007763)
13. Gutmann DH, Giordano MJ, Fishback AS, et al: Loss of merlin expression in sporadic meningiomas, ependymomas and schwannomas. Neurology 49:267-270, 1997 (Pubitemid 27328718)
14. Creuzet SE: Neural crest contribution to forebrain development. Semin Cell Dev Biol 20:751-759, 2009
15. Küsters-Vandevelde HV, Klaasen A, Küsters B, et al: Activating mutations of the GNAQ gene: A frequent event in primary melanocytic neoplasms of the central nervous system. Acta Neuropathol 119:317-323, 2010