Clinical characteristics and outcomes associated with the natural history of early repolarization in a young, biracial cohort followed to middle age: The Coronary Artery Risk Development in Young Adults (CARDIA) study

Circulation: Arrhythmia and Electrophysiology

Volumn 7, Issue 3, 2014, Pages 392-399

  Ilkhanoff, Leonard ^a   Soliman, Elsayed Z ^d   Prineas, Ronald J ^e   Walsh III, Joseph A ^b   Ning, Hongyan ^c   Liu, Kiang ^c   Carr, J Jeffrey ^f,h   Jacobs Jr , David R ^g   Lloyd Jones, Donald M ^b,c  

^a Department of Medicine   (United States)

^b Division of Cardiology   (United States)

^c NORTHWESTERN UNIVERSITY   (United States)

^d Department of Epidemiology and Prevention Epidemiological Cardiology Research Center (EPICARE)   (United States)

^e Division of Public Health Sciences   (United States)

^f WAKE FOREST SCHOOL OF MEDICINE   (United States)

^g UNIVERSITY OF MINNESOTA   (United States)

^h VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Electrocardiography; Mortality

Indexed keywords

ELECTROCARDIOGRAPHY; MORTALITY;

ADULT; AFRICAN CONTINENTAL ANCESTRY GROUP; AGE FACTORS; ARRHYTHMIAS, CARDIAC; CARDIOVASCULAR DISEASES; CAUSE OF DEATH; COHORT STUDIES; CONFIDENCE INTERVALS; ECHOCARDIOGRAPHY; ELECTROCARDIOGRAPHY; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; FOLLOW-UP STUDIES; HEART CONDUCTION SYSTEM; HUMANS; KAPLAN-MEIER ESTIMATE; MALE; MIDDLE AGED; PROPORTIONAL HAZARDS MODELS; PROSPECTIVE STUDIES; RISK ASSESSMENT; SEX FACTORS; SURVIVAL RATE; TIME FACTORS; YOUNG ADULT;

EID: 84905853887     PISSN: 19413149     EISSN: 19413084     Source Type: Journal    
DOI: 10.1161/CIRCEP.113.000874     Document Type: Article

References (21)

1. Sutherland SE, Gazes PC, Keil JE, Gilbert GE, Knapp RG. Electrocardiographic abnormalities and 30-year mortality among white and black men of the Charleston Heart Study. Circulation. 1993;88:2685-2692.
2. Machado DB, Crow RS, Boland LL, Hannan PJ, Taylor HA Jr, Folsom AR. Electrocardiographic fndings and incident coronary heart disease among participants in the Atherosclerosis Risk in Communities (ARIC) study. Am J Cardiol. 2006;97:1176-1181.
3. Klatsky AL, Oehm R, Cooper RA, Udaltsova N, Armstrong MA. The early repolarization normal variant electrocardiogram: correlates and consequences. Am J Med. 2003;115:171-177.
4. Walsh JA, Ilkhanoff L, Soliman EZ, Prineas R, Liu K, Ning H, LloydJones DM. Natural history of early repolarization syndrome: Coronary Artery Risk Development in Young Adults (CARDIA) study. J Am Coll Cardiol. 2013;61:863-869.
5. Uberoi A, Jain NA, Perez M, Weinkopff A, Ashley E, Hadley D, Turakhia MP, Froelicher V. Early repolarization in an ambulatory clinical population. Circulation. 2011;124:2208-2214.
6. Perez MV, Uberoi A, Jain NA, Ashley E, Turakhia MP, Froelicher V. The prognostic value of early repolarization with ST-segment elevation in African Americans. Heart Rhythm. 2012;9:558-565.
7. Haïssaguerre M, Derval N, Sacher F, Jesel L, Deisenhofer I, de Roy L, Pasquié JL, Nogami A, Babuty D, Yli-Mayry S, De Chillou C, Scanu P, Mabo P, Matsuo S, Probst V, Le Scouarnec S, Defaye P, Schlaepfer J, Rostock T, Lacroix D, Lamaison D, Lavergne T, Aizawa Y, Englund A, Anselme F, O'Neill M, Hocini M, Lim KT, Knecht S, Veenhuyzen GD, Bordachar P, Chauvin M, Jais P, Coureau G, Chene G, Klein GJ, Clémenty J. Sudden cardiac arrest associated with early repolarization. N Engl J Med. 2008;358:2016-2023.
8. Rosso R, Kogan E, Belhassen B, Rozovski U, Scheinman MM, Zeltser D, Halkin A, Steinvil A, Heller K, Glikson M, Katz A, Viskin S. J-point elevation in survivors of primary ventricular fbrillation and matched control subjects: incidence and clinical signifcance. J Am Coll Cardiol. 2008;52:1231-1238.
9. Tikkanen JT, Anttonen O, Junttila MJ, Aro AL, Kerola T, Rissanen HA, Reunanen A, Huikuri HV. Long-term outcome associated with early repo-larization on electrocardiography. N Engl J Med. 2009;361:2529-2537.
10. Haruta D, Matsuo K, Tsuneto A, Ichimaru S, Hida A, Sera N, Imaizumi M, Nakashima E, Maemura K, Akahoshi M. Incidence and prognostic value of early repolarization pattern in the 12-lead electrocardiogram. Circulation. 2011;123:2931-2937.
11. Friedman GD, Cutter GR, Donahue RP, Hughes GH, Hulley SB, Jacobs DRJ, Liu K, Savage PJ. CARDIA: study design, recruitment, and some characteristics of the examined subjects. J Clin Epidemiol. 1988;41:1105-1116.
12. Rautaharju PM, Wolf HK, Eifer WJ, Blackburn H. A simple procedure for positioning precordial ECG and VCG electrodes using an electrode locator. J Electrocardiol. 1976;9:35-40.
13. Prineas RJ, Crow RS, Blackburn H. The Minnesota Code Manual of Electrocardiographic Findings: Standards and Procedures for Measurement and Classifcation. Boston, MA: John Wright-PSG, Inc; 1982.
14. Soliman EZ, Elsalam MA, Li Y. Early repolarization and markers of ventricular arrhythmogenesis in patients referred to ambulatory 24-hour ECG recording. Int J Cardiol. 2012;160:175-180.
15. Bibbins-Domingo K, Pletcher MJ, Lin F, Vittinghoff E, Gardin JM, Arynchyn A, Lewis CE, Williams OD, Hulley SB. Racial differences in incident heart failure among young adults. N Engl J Med. 2009;360:1179-1190.
16. Patel RB, Ng J, Reddy V, Chokshi M, Parikh K, Subacius H, Alsheikh-Ali AA, Nguyen T, Link MS, Goldberger JJ, Ilkhanoff L, Kadish AH. Early re-polarization associated with ventricular arrhythmias in patients with chronic coronary artery disease. Circ Arrhythm Electrophysiol. 2010;3:489-495.
17. Naruse Y, Tada H, Harimura Y, Hayashi M, Noguchi Y, Sato A, Yoshida K, Sekiguchi Y, Aonuma K. Early repolarization is an independent predictor of occurrences of ventricular fbrillation in the very early phase of acute myocardial infarction. Circ Arrhythm Electrophysiol. 2012;5:506-513.
18. Patel RB, Ilkhanoff L, Ng J, Chokshi M, Mouchli A, Chacko SJ, Subacius H, Bhojraj S, Goldberger JJ, Kadish AH. Clinical characteristics and prevalence of early repolarization associated with ventricular arrhythmias following acute ST-elevation myocardial infarction. Am J Cardiol. 2012;110:615-620.
19. Noseworthy PA, Weiner R, Kim J, Keelara V, Wang F, Berkstresser B, Wood MJ, Wang TJ, Picard MH, Hutter AM Jr, Newton-Cheh C, Baggish AL. Early repolarization pattern in competitive athletes: clinical correlates and the effects of exercise training. Circ Arrhythm Electrophysiol. 2011;4:432-440.
20. Noseworthy PA, Tikkanen JT, Porthan K, Oikarinen L, Pietilä A, Harald K, Peloso GM, Merchant FM, Jula A, Väänänen H, Hwang SJ, O'Donnell CJ, Salomaa V, Newton-Cheh C, Huikuri HV. The early repolarization pattern in the general population: clinical correlates and heritability. J Am Coll Cardiol. 2011;57:2284-2289.
21. Olson KA, Viera AJ, Soliman EZ, Crow RS, Rosamond WD. Long-term prognosis associated with J-point elevation in a large middle-aged biracial cohort: the ARIC study. Eur Heart J. 2011;32:3098-3106.