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Volumn 10, Issue 8, 2014, Pages 1426-1441

Coronavirus NSP6 restricts autophagosome expansion

Author keywords

Autophagosome quantification; Autophagy; Coronavirus; MHV; Nonstructural proteins; Omegasome; SARS

Indexed keywords

MAMMALIAN TARGET OF RAPAMYCIN; NONSTRUCTURAL PROTEIN 5; NONSTRUCTURAL PROTEIN 6; NONSTRUCTURAL PROTEIN 7; TORIN1 PROTEIN; UNCLASSIFIED DRUG; VIRUS PROTEIN; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TARGET OF RAPAMYCIN KINASE;

EID: 84905828980     PISSN: 15548627     EISSN: 15548635     Source Type: Journal    
DOI: 10.4161/auto.29309     Document Type: Article
Times cited : (220)

References (38)
  • 1
    • 0038309329 scopus 로고    scopus 로고
    • The molecular mechanism of autophagy
    • PMID:12865942
    • Wang CW, Klionsky DJ. The molecular mechanism of autophagy. Mol Med 2003; 9:65-76; PMID:12865942
    • (2003) Mol Med , vol.9 , pp. 65-76
    • Wang, C.W.1    Klionsky, D.J.2
  • 2
    • 64049113909 scopus 로고    scopus 로고
    • Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1-phosphatidylinositol-3-kinase complex
    • PMID:19270693
    • Zhong Y, Wang QJ, Li X, Yan Y, Backer JM, Chait BT, Heintz N, Yue Z. Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1-phosphatidylinositol-3-kinase complex. Nat Cell Biol 2009; 11:468-76; PMID:19270693; http://dx.doi.org/10.1038/ncb1854
    • (2009) Nat Cell Biol , vol.11 , pp. 468-476
    • Zhong, Y.1    Wang, Q.J.2    Li, X.3    Yan, Y.4    Backer, J.M.5    Chait, B.T.6    Heintz, N.7    Yue, Z.8
  • 3
    • 77955895424 scopus 로고    scopus 로고
    • Autophagy requires endoplasmic reticulum targeting of the PI3-kinase complex via Atg14L
    • PMID:20713597
    • Matsunaga K, Morita E, Saitoh T, Akira S, Ktistakis NT, Izumi T, Noda T, Yoshimori T. Autophagy requires endoplasmic reticulum targeting of the PI3-kinase complex via Atg14L. J Cell Biol 2010; 190:511-21; PMID:20713597; http://dx.doi.org/10.1083/jcb.200911141
    • (2010) J Cell Biol , vol.190 , pp. 511-521
    • Matsunaga, K.1    Morita, E.2    Saitoh, T.3    Akira, S.4    Ktistakis, N.T.5    Izumi, T.6    Noda, T.7    Yoshimori, T.8
  • 5
    • 50249084987 scopus 로고    scopus 로고
    • Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum
    • PMID:18725538
    • Axe EL, Walker SA, Manifava M, Chandra P, Roderick HL, Habermann A, Griffiths G, Ktistakis NT. Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum. J Cell Biol 2008; 182:685-701; PMID:18725538; http://dx.doi.org/10.1083/jcb.200803137
    • (2008) J Cell Biol , vol.182 , pp. 685-701
    • Axe, E.L.1    Walker, S.A.2    Manifava, M.3    Chandra, P.4    Roderick, H.L.5    Habermann, A.6    Griffiths, G.7    Ktistakis, N.T.8
  • 6
    • 11244289333 scopus 로고    scopus 로고
    • WIPI-1alpha (WIPI49), a member of the novel 7-bladed WIPI protein family, is aberrantly expressed in human cancer and is linked to starvation-induced autophagy
    • PMID:15602573
    • Proikas-Cezanne T, Waddell S, Gaugel A, Frickey T, Lupas A, Nordheim A. WIPI-1alpha (WIPI49), a member of the novel 7-bladed WIPI protein family, is aberrantly expressed in human cancer and is linked to starvation-induced autophagy. Oncogene 2004; 23:9314-25; PMID:15602573; http://dx.doi.org/10.1038/ sj.onc.1208331
    • (2004) Oncogene , vol.23 , pp. 9314-9325
    • Proikas-Cezanne, T.1    Waddell, S.2    Gaugel, A.3    Frickey, T.4    Lupas, A.5    Nordheim, A.6
  • 7
    • 77953726483 scopus 로고    scopus 로고
    • Mammalian Atg18 (WIPI2) localizes to omegasome-anchored phagophores and positively regulates LC3 lipidation
    • PMID:20505359
    • Polson HE, de Lartigue J, Rigden DJ, Reedijk M, Urbé S, Clague MJ, Tooze SA. Mammalian Atg18 (WIPI2) localizes to omegasome-anchored phagophores and positively regulates LC3 lipidation. Autophagy 2010; 6:506-22; PMID:20505359; http://dx.doi.org/10.4161/auto.6.4.11863
    • (2010) Autophagy , vol.6 , pp. 506-522
    • Polson, H.E.1    De Lartigue, J.2    Rigden, D.J.3    Reedijk, M.4    Urbé, S.5    Clague, M.J.6    Tooze, S.A.7
  • 8
    • 77950506156 scopus 로고    scopus 로고
    • Regulation of autophagy by phosphatidylinositol 3-phosphate
    • PMID:20074568
    • Burman C, Ktistakis NT. Regulation of autophagy by phosphatidylinositol 3-phosphate. FEBS Lett 2010; 584:1302-12; PMID:20074568; http://dx.doi.org/10. 1016/j.febslet.2010.01.011
    • (2010) FEBS Lett , vol.584 , pp. 1302-1312
    • Burman, C.1    Ktistakis, N.T.2
  • 9
    • 77950465542 scopus 로고    scopus 로고
    • Current knowledge of the pre-autophagosomal structure (PAS)
    • PMID:20138172
    • Suzuki K, Ohsumi Y. Current knowledge of the pre-autophagosomal structure (PAS). FEBS Lett 2010; 584:1280-6; PMID:20138172; http://dx.doi.org/10.1016/j. febslet.2010.02.001
    • (2010) FEBS Lett , vol.584 , pp. 1280-1286
    • Suzuki, K.1    Ohsumi, Y.2
  • 10
    • 12944308330 scopus 로고    scopus 로고
    • Eating oneself and uninvited guests: Autophagy-related pathways in cellular defense
    • PMID:15680321
    • Levine B. Eating oneself and uninvited guests: autophagy-related pathways in cellular defense. Cell 2005; 120:159-62; PMID:15680321
    • (2005) Cell , vol.120 , pp. 159-162
    • Levine, B.1
  • 11
    • 70349650684 scopus 로고    scopus 로고
    • VSV infection is sensed by Drosophila, attenuates nutrient signaling, and thereby activates antiviral autophagy
    • PMID:19713743
    • Cherry S. VSV infection is sensed by Drosophila, attenuates nutrient signaling, and thereby activates antiviral autophagy. Autophagy 2009; 5:1062-3; PMID:19713743; http://dx.doi.org/10.4161/auto.5.7.9730
    • (2009) Autophagy , vol.5 , pp. 1062-1063
    • Cherry, S.1
  • 12
    • 67349269904 scopus 로고    scopus 로고
    • Autophagy enhances the presentation of endogenous viral antigens on MHC class I molecules during HSV-1 infection
    • PMID:19305394
    • English L, Chemali M, Duron J, Rondeau C, Laplante A, Gingras D, Alexander D, Leib D, Norbury C, Lippé R, et al. Autophagy enhances the presentation of endogenous viral antigens on MHC class I molecules during HSV-1 infection. Nat Immunol 2009; 10:480-7; PMID:19305394; http://dx.doi.org/10.1038/ ni.1720
    • (2009) Nat Immunol , vol.10 , pp. 480-487
    • English, L.1    Chemali, M.2    Duron, J.3    Rondeau, C.4    Laplante, A.5    Gingras, D.6    Alexander, D.7    Leib, D.8    Norbury, C.9    Lippé, R.10
  • 13
    • 76249112828 scopus 로고    scopus 로고
    • Autophagy protects against Sindbis virus infection of the central nervous system
    • PMID:20159618
    • Orvedahl A, MacPherson S, Sumpter R Jr., Tallóczy Z, Zou Z, Levine B. Autophagy protects against Sindbis virus infection of the central nervous system. Cell Host Microbe 2010; 7:115-27; PMID:20159618; http://dx.doi.org/10. 1016/j.chom.2010.01.007
    • (2010) Cell Host Microbe , vol.7 , pp. 115-127
    • Orvedahl, A.1    MacPherson, S.2    Sumpter Jr., R.3    Tallóczy, Z.4    Zou, Z.5    Levine, B.6
  • 14
    • 73849132170 scopus 로고    scopus 로고
    • Origins of membrane vesicles generated during replication of positive-strand RNA viruses
    • Cottam E, Pierini R, Roberts R, Wileman T. Origins of membrane vesicles generated during replication of positive-strand RNA viruses. Future Virol 2009; 4:473-85; http://dx.doi.org/10.2217/fvl.09.26
    • (2009) Future Virol , vol.4 , pp. 473-485
    • Cottam, E.1    Pierini, R.2    Roberts, R.3    Wileman, T.4
  • 16
    • 75649122282 scopus 로고    scopus 로고
    • Subversion of the cellular autophagy pathway by viruses
    • PMID:19802573
    • Kirkegaard K. Subversion of the cellular autophagy pathway by viruses. Curr Top Microbiol Immunol 2009; 335:323-33; PMID:19802573; http://dx.doi.org/ 10.1007/978-3-642-00302-8-16
    • (2009) Curr Top Microbiol Immunol , vol.335 , pp. 323-333
    • Kirkegaard, K.1
  • 17
    • 33646555141 scopus 로고    scopus 로고
    • Aggresomes and autophagy generate sites for virus replication
    • PMID:16690857
    • Wileman T. Aggresomes and autophagy generate sites for virus replication. Science 2006; 312:875-8; PMID:16690857; http://dx.doi.org/10.1126/science. 1126766
    • (2006) Science , vol.312 , pp. 875-878
    • Wileman, T.1
  • 19
    • 0033798416 scopus 로고    scopus 로고
    • Remodeling the endoplasmic reticulum by poliovirus infection and by individual viral proteins: An autophagy-like origin for virus-induced vesicles
    • PMID:10982339
    • Suhy DA, Giddings TH Jr., Kirkegaard K. Remodeling the endoplasmic reticulum by poliovirus infection and by individual viral proteins: an autophagy-like origin for virus-induced vesicles. J Virol 2000; 74:8953-65; PMID:10982339; http://dx.doi.org/10.1128/JVI.74.19.8953-8965.2000
    • (2000) J Virol , vol.74 , pp. 8953-8965
    • Suhy, D.A.1    Giddings Jr., T.H.2    Kirkegaard, K.3
  • 20
    • 36049014444 scopus 로고    scopus 로고
    • Modification of cellular autophagy protein LC3 by poliovirus
    • PMID:17804493
    • Taylor MP, Kirkegaard K. Modification of cellular autophagy protein LC3 by poliovirus. J Virol 2007; 81:12543-53; PMID:17804493; http://dx.doi.org/10. 1128/JVI.00755-07
    • (2007) J Virol , vol.81 , pp. 12543-12553
    • Taylor, M.P.1    Kirkegaard, K.2
  • 21
    • 80054978956 scopus 로고    scopus 로고
    • Rab5 and class III phosphoinositide 3-kinase Vps34 are involved in hepatitis C virus NS4B-induced autophagy
    • PMID:21835792
    • Su WC, Chao TC, Huang YL, Weng SC, Jeng KS, Lai MM. Rab5 and class III phosphoinositide 3-kinase Vps34 are involved in hepatitis C virus NS4B-induced autophagy. J Virol 2011; 85:10561-71; PMID:21835792; http://dx.doi.org/10.1128/ JVI.00173-11
    • (2011) J Virol , vol.85 , pp. 10561-10571
    • Su, W.C.1    Chao, T.C.2    Huang, Y.L.3    Weng, S.C.4    Jeng, K.S.5    Lai, M.M.6
  • 22
    • 64049114864 scopus 로고    scopus 로고
    • Autophagy is an essential component of Drosophila immunity against vesicular stomatitis virus
    • PMID:19362021
    • Shelly S, Lukinova N, Bambina S, Berman A, Cherry S. Autophagy is an essential component of Drosophila immunity against vesicular stomatitis virus. Immunity 2009; 30:588-98; PMID:19362021; http://dx.doi.org/10.1016/j.immuni. 2009.02.009
    • (2009) Immunity , vol.30 , pp. 588-598
    • Shelly, S.1    Lukinova, N.2    Bambina, S.3    Berman, A.4    Cherry, S.5
  • 23
    • 84873280040 scopus 로고    scopus 로고
    • The p17 nonstructural protein of avian reovirus triggers autophagy enhancing virus replication via activation of phosphatase and tensin deleted on chromosome 10 (PTEN) and AMP-activated protein kinase (AMPK), as well as dsRNA-dependent protein kinase (PKR)/eIF2α signaling pathways
    • PMID:23233667
    • Chi PI, Huang WR, Lai IH, Cheng CY, Liu HJ. The p17 nonstructural protein of avian reovirus triggers autophagy enhancing virus replication via activation of phosphatase and tensin deleted on chromosome 10 (PTEN) and AMP-activated protein kinase (AMPK), as well as dsRNA-dependent protein kinase (PKR)/eIF2α signaling pathways. J Biol Chem 2013; 288:3571-84; PMID:23233667; http://dx.doi.org/10.1074/jbc.M112.390245
    • (2013) J Biol Chem , vol.288 , pp. 3571-3584
    • Chi, P.I.1    Huang, W.R.2    Lai, I.H.3    Cheng, C.Y.4    Liu, H.J.5
  • 24
    • 69249229790 scopus 로고    scopus 로고
    • Simian virus 40 small T antigen activates AMPK and triggers autophagy to protect cancer cells from nutrient deprivation
    • PMID:19515765
    • Kumar SH, Rangarajan A. Simian virus 40 small T antigen activates AMPK and triggers autophagy to protect cancer cells from nutrient deprivation. J Virol 2009; 83:8565-74; PMID:19515765; http://dx.doi.org/10.1128/JVI.00603-09
    • (2009) J Virol , vol.83 , pp. 8565-8574
    • Kumar, S.H.1    Rangarajan, A.2
  • 25
    • 34147160583 scopus 로고    scopus 로고
    • Coronavirus avian infectious bronchitis virus
    • PMID:17296157
    • Cavanagh D. Coronavirus avian infectious bronchitis virus. Vet Res 2007; 38:281-97; PMID:17296157; http://dx.doi.org/10.1051/vetres:2006055
    • (2007) Vet Res , vol.38 , pp. 281-297
    • Cavanagh, D.1
  • 26
    • 84857815535 scopus 로고    scopus 로고
    • Ultrastructural characterization of arterivirus replication structures: Reshaping the endoplasmic reticulum to accommodate viral RNA synthesis
    • PMID:22190716
    • Knoops K, Bárcena M, Limpens RW, Koster AJ, Mommaas AM, Snijder EJ. Ultrastructural characterization of arterivirus replication structures: reshaping the endoplasmic reticulum to accommodate viral RNA synthesis. J Virol 2012; 86:2474-87; PMID:22190716; http://dx.doi.org/10.1128/JVI.06677-11
    • (2012) J Virol , vol.86 , pp. 2474-2487
    • Knoops, K.1    Bárcena, M.2    Limpens, R.W.3    Koster, A.J.4    Mommaas, A.M.5    Snijder, E.J.6
  • 29
    • 34848886914 scopus 로고    scopus 로고
    • Autophagosome formation: Core machinery and adaptations
    • PMID:17909521
    • Xie Z, Klionsky DJ. Autophagosome formation: core machinery and adaptations. Nat Cell Biol 2007; 9:1102-9; PMID:17909521; http://dx.doi.org/10. 1038/ncb1007-1102
    • (2007) Nat Cell Biol , vol.9 , pp. 1102-1109
    • Xie, Z.1    Klionsky, D.J.2
  • 30
    • 77953699711 scopus 로고    scopus 로고
    • Termination of autophagy and reformation of lysosomes regulated by mTOR
    • PMID:20526321
    • Yu L, McPhee CK, Zheng L, Mardones GA, Rong Y, Peng J, Mi N, Zhao Y, Liu Z, Wan F, et al. Termination of autophagy and reformation of lysosomes regulated by mTOR. Nature 2010; 465:942-6; PMID:20526321; http://dx.doi.org/10.1038/ nature09076
    • (2010) Nature , vol.465 , pp. 942-946
    • Yu, L.1    McPhee, C.K.2    Zheng, L.3    Mardones, G.A.4    Rong, Y.5    Peng, J.6    Mi, N.7    Zhao, Y.8    Liu, Z.9    Wan, F.10
  • 31
    • 34548259958 scopus 로고    scopus 로고
    • p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy
    • PMID:17580304
    • Pankiv S, Clausen TH, Lamark T, Brech A, Bruun JA, Outzen H, Øvervatn A, Bjørkøy G, Johansen T. p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy. J Biol Chem 2007; 282:24131-45; PMID:17580304; http://dx.doi.org/10.1074/jbc.M702824200
    • (2007) J Biol Chem , vol.282 , pp. 24131-24145
    • Pankiv, S.1    Clausen, T.H.2    Lamark, T.3    Brech, A.4    Bruun, J.A.5    Outzen, H.6    Øvervatn, A.7    Bjørkøy, G.8    Johansen, T.9
  • 32
    • 84873677330 scopus 로고    scopus 로고
    • An autophagy-independent role for LC3 in equine arteritis virus replication
    • PMID:23182945
    • Monastyrska I, Ulasli M, Rottier PJ, Guan JL, Reggiori F, de Haan CA. An autophagy-independent role for LC3 in equine arteritis virus replication. Autophagy 2013; 9:164-74; PMID:23182945; http://dx.doi.org/10.4161/auto.22743
    • (2013) Autophagy , vol.9 , pp. 164-174
    • Monastyrska, I.1    Ulasli, M.2    Rottier, P.J.3    Guan, J.L.4    Reggiori, F.5    De Haan, C.A.6
  • 33
    • 77956525570 scopus 로고    scopus 로고
    • Coronaviruses Hijack the LC3-I-positive EDEMosomes, ER-derived vesicles exporting short-lived ERAD regulators, for replication
    • PMID:20542253
    • Reggiori F, Monastyrska I, Verheije MH, Calì T, Ulasli M, Bianchi S, Bernasconi R, de Haan CA, Molinari M. Coronaviruses Hijack the LC3-I-positive EDEMosomes, ER-derived vesicles exporting short-lived ERAD regulators, for replication. Cell Host Microbe 2010; 7:500-8; PMID:20542253; http://dx.doi.org/10.1016/j.chom.2010.05.013
    • (2010) Cell Host Microbe , vol.7 , pp. 500-508
    • Reggiori, F.1    Monastyrska, I.2    Verheije, M.H.3    Calì, T.4    Ulasli, M.5    Bianchi, S.6    Bernasconi, R.7    De Haan, C.A.8    Molinari, M.9
  • 34
    • 1642280930 scopus 로고    scopus 로고
    • Coronavirus replication complex formation utilizes components of cellular autophagy
    • PMID:14699140
    • Prentice E, Jerome WG, Yoshimori T, Mizushima N, Denison MR. Coronavirus replication complex formation utilizes components of cellular autophagy. J Biol Chem 2004; 279:10136-41; PMID:14699140; http://dx.doi.org/10.1074/jbc.M306124200
    • (2004) J Biol Chem , vol.279 , pp. 10136-10141
    • Prentice, E.1    Jerome, W.G.2    Yoshimori, T.3    Mizushima, N.4    Denison, M.R.5
  • 35
    • 84867250922 scopus 로고    scopus 로고
    • Porcine reproductive and respiratory syndrome virus induces autophagy to promote virus replication
    • PMID:22739997
    • Sun MX, Huang L, Wang R, Yu YL, Li C, Li PP, Hu XC, Hao HP, Ishag HA, Mao X. Porcine reproductive and respiratory syndrome virus induces autophagy to promote virus replication. Autophagy 2012; 8:1434-47; PMID:22739997; http://dx.doi.org/10.4161/auto.21159
    • (2012) Autophagy , vol.8 , pp. 1434-1447
    • Sun, M.X.1    Huang, L.2    Wang, R.3    Yu, Y.L.4    Li, C.5    Li, P.P.6    Hu, X.C.7    Hao, H.P.8    Ishag, H.A.9    Mao, X.10
  • 37
    • 33645120442 scopus 로고    scopus 로고
    • Microtubules facilitate autophagosome formation and fusion of autophagosomes with endosomes
    • PMID:16420522
    • Köchl R, Hu XW, Chan EY, Tooze SA. Microtubules facilitate autophagosome formation and fusion of autophagosomes with endosomes. Traffic 2006; 7:129-45; PMID:16420522; http://dx.doi.org/10.1111/j.1600-0854.2005.00368. x
    • (2006) Traffic , vol.7 , pp. 129-145
    • Köchl, R.1    Hu, X.W.2    Chan, E.Y.3    Tooze, S.A.4
  • 38
    • 84877316772 scopus 로고    scopus 로고
    • Visualizing the autophagy pathway in avian cells and its application to studying infectious bronchitis virus
    • PMID:23328491
    • Maier HJ, Cottam EM, Stevenson-Leggett P, Wilkinson JA, Harte CJ, Wileman T, Britton P. Visualizing the autophagy pathway in avian cells and its application to studying infectious bronchitis virus. Autophagy 2013; 9:496-509; PMID:23328491; http://dx.doi.org/10.4161/auto.23465
    • (2013) Autophagy , vol.9 , pp. 496-509
    • Maier, H.J.1    Cottam, E.M.2    Stevenson-Leggett, P.3    Wilkinson, J.A.4    Harte, C.J.5    Wileman, T.6    Britton, P.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.