Simple and rapid determination of zafirlukast in plasma by ultra-performance liquid chromatography tandem mass spectrometric method: Application into pharmacokinetic study in rabbits

Drug Research

Volumn 64, Issue 8, 2014, Pages 412-419

  Iqbal, M ^a   Ezzeldin, E ^a   Al Rashood, K A ^a   Al Khamees, K I ^a   Khan, R M A ^a   Raish, M ^a   Anwer, T ^b  

^a KING SAUD UNIVERSITY   (Saudi Arabia)

^b JAZAN UNIVERSITY   (Saudi Arabia)

Author keywords

high throughput analysis; pharmacokinetics; tandem mass spectrometry; ultra performance liquid chromatography; zafirlukast

Indexed keywords

ACETIC ACID; ACETONITRILE; MONTELUKAST; WATER; ZAFIRLUKAST; DYES, REAGENTS, INDICATORS, MARKERS AND BUFFERS; LEUKOTRIENE RECEPTOR BLOCKING AGENT; TOLUENESULFONIC ACID DERIVATIVE;

ACCURACY; ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG HALF LIFE; LIMIT OF QUANTITATION; MALE; MAXIMUM PLASMA CONCENTRATION; MEAN RESIDENCE TIME; NONHUMAN; PLASMA; RABBIT; ROOM TEMPERATURE; STORAGE; TANDEM MASS SPECTROMETRY; TIME TO MAXIMUM PLASMA CONCENTRATION; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; ANIMAL; BLOOD; CALIBRATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; QUALITY CONTROL; REPRODUCIBILITY;

ANIMALS; CALIBRATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; INDICATORS AND REAGENTS; LEUKOTRIENE ANTAGONISTS; MALE; QUALITY CONTROL; RABBITS; REPRODUCIBILITY OF RESULTS; TANDEM MASS SPECTROMETRY; TOSYL COMPOUNDS;

EID: 84905821434     PISSN: 21949379     EISSN: 21949387     Source Type: Journal    
DOI: 10.1055/s-0033-1358748     Document Type: Article

References (16)

1. Prescribing information of ACCOLATE (zafirlukast) AstraZeneca Pharmaceuticals LP, UK. Downloaded from http://dailymed.nlm.nih.gov/dailymed/ lookup.cfm?setid=5550433b-8c9c-4378-058f-6bb724c4f18c (accessed on April 13, 2013)
2. Fischer J. D., Song M. H., Suttle A. B. et al. Comparison of zafirlukast (Accolate) absorption after oral and colonic administration in humans. Pharmceutical Research: 2000; 17 154 159 (Pubitemid 30158363)
3. Shubha R., Swati G., Anjali Z. et al. Zafirlukast Pharmacokinetics in Healthy Indian Male Subjects: Interethnic Variability. Indian Journal of Allergy Asthma Immunol: 2005; 19 69 73
4. Dekhuijzen P. N., Koopmans P. P. Pharmacokinetic profile of zafirlukast. Clinical Pharmacokinetics: 2002; 41 105 114 (Pubitemid 34264037)
5. Ficarra R., Ficarra P., Tommasini S. et al. Validation of a LC method for the analysis of zafirlukast in a pharmaceutical formulation. J Pharm Biomedical Analysis: 2000; 23 169 174 (Pubitemid 30394564)
6. Radhakrishna T., Satyanarayana J., Satyanarayana A. Determination of zafirlukast by stability indicating LC and derivative spectrophotometry. J Pharm Biomedical Analysis: 2002; 30 695 703 (Pubitemid 35279696)
7. Suslu I., Altinoz S. A reversed-phase high-performance liquid chromatographic method for the determination of ZFR in pharmaceutical formulations and human plasma. J AOAC International: 2006; 89 1557 1564 (Pubitemid 46009912)
8. Süslü I., Demircan S., Altinöz S. et al. Optimisation, validation and application of a capillary electrophoretic method for the determination of zafirlukast in pharmaceutical formulations. J Pharm Biomed Anal: 2007; 44 16 22 (Pubitemid 46551572)
9. Süslü I., Altinöz S. Electrochemical characteristics of zafirlukast and its determination in pharmaceutical formulations by voltammetric methods. J Pharm Biomedical Analysis: 2005; 39 535 542 (Pubitemid 41196060)
10. Goverdhan G., Reddy A. R., Srinivas K. et al. Identification, characterization and synthesis of impurities of zafirlukast. J Pharm Biomedical Analysis: 2009; 49 895 900
11. Thiyagarajan T. K., Abdul Hakeem J. A., Baksam V. Development of a stability-indicating RP-LC method for the separation of a critical pair of impurities and their degradants in zafirlukast. J Chromatogrphy Science: 2012; 50 945 952
12. Bui K. H., Kennedy C. M., Azumaya C. T. et al. Determination of zafirlukast, a selective leukotriene antagonist, human plasma by normal-phase high-performance liquid chromatography with fluorescence detection. J Chromatogrphy B Biomedical Science Appl: 1997; 696 131 136 (Pubitemid 27366097)
13. Bharathi D. V., Naidu A., Jagadeesh B. et al. Development and validation of a sensitive LC-MS/MS method with electrospray ionization for quantitation of zafirlukast, a selective leukotriene antagonist in human plasma: application to a clinical pharmacokinetic study. Biomedical Chromatography: 2008; 22 645 653 (Pubitemid 351959415)
14. Guideline on bioanalytical method validation European Medicines Agency, EMEA/CHMP/EWP192217/2009. 1 February 2012 http://www.ema.europa.eu/docs/en-GB/ document-library/Scientific-guideline/2011/08/WC500109686.pdf (accessed April 19, 2013)
15. Guidance for Industry on Bioanalytical Method Validation US Food and Drug Administration, Center for Drug Evaluation and Research (CDER). Rockville, MD Department of Health and Human Services: 2001
16. Wu Z., Gao W., Phelps M. A. et al. Favorable effects of weak acids on negative-ion electrospray ionization mass spectrometry. Analytical Chemistry: 2004; 76 839 847 (Pubitemid 38166594)