-
1
-
-
63849328927
-
New prognostic scoring system for primary myelofibrosis based on a study of the International Working Group for Myelofibrosis Research and Treatment
-
Cervantes F, Dupriez B, Pereira A et al (2009) New prognostic scoring system for primary myelofibrosis based on a study of the International Working Group for Myelofibrosis Research and Treatment. Blood 113(13): 2895-2901.
-
(2009)
Blood
, vol.113
, Issue.13
, pp. 2895-2901
-
-
Cervantes, F.1
Dupriez, B.2
Pereira, A.3
-
2
-
-
84857837774
-
JAK inhibition with ruxolitinib versus best available therapy for myelofibrosis
-
Harrison C, Kiladjian JJ, Al-Ali HK et al (2012a) JAK inhibition with ruxolitinib versus best available therapy for myelofibrosis. N Engl J Med 366(9): 787-798.
-
(2012)
N Engl J Med
, vol.366
, Issue.9
, pp. 787-798
-
-
Harrison, C.1
Kiladjian, J.J.2
Al-Ali, H.K.3
-
4
-
-
17844383458
-
A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera
-
James C, Ugo V, Le Couédic JP et al (2005) A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera. Nature 434(7037): 1144-1148.
-
(2005)
Nature
, vol.434
, Issue.7037
, pp. 1144-1148
-
-
James, C.1
Ugo, V.2
Le Couédic, J.P.3
-
5
-
-
84880252493
-
A comprehensive review and analysis of the effect of ruxolitinib therapy on the survival of patients with myelofibrosis
-
Mascarenhas J, Hoffman R (2013) A comprehensive review and analysis of the effect of ruxolitinib therapy on the survival of patients with myelofibrosis. Blood 121(24): 4832-4837.
-
(2013)
Blood
, vol.121
, Issue.24
, pp. 4832-4837
-
-
Mascarenhas, J.1
Hoffman, R.2
-
6
-
-
35548944961
-
SnapShot: JAK-STAT signaling
-
Mertens C, Darnell JE Jr (2007) SnapShot: JAK-STAT signaling. Cell 131(3): 612.
-
(2007)
Cell
, vol.131
, Issue.3
, pp. 612
-
-
Mertens, C.1
Darnell, J.E.2
-
8
-
-
84876082159
-
Effect of ruxolitinib therapy on myelofibrosis-related symptoms and other patient-reported outcomes in COMFORT-I: A randomized, double-blind, placebo-controlled trial
-
Mesa RA, Gotlib J, Gupta V et al (2013) Effect of ruxolitinib therapy on myelofibrosis-related symptoms and other patient-reported outcomes in COMFORT-I: a randomized, double-blind, placebo-controlled trial. J Clin Oncol 31(10): 1285-1292.
-
(2013)
J Clin Oncol
, vol.31
, Issue.10
, pp. 1285-1292
-
-
Mesa, R.A.1
Gotlib, J.2
Gupta, V.3
-
9
-
-
77950684805
-
Preclinical characterization of the selective JAK1/2 inhibitor INCB018424: Therapeutic implications for the treatment of myeloproliferative neoplasms
-
Quintás-Cardama A, Vaddi K, Liu P et al (2010) Preclinical characterization of the selective JAK1/2 inhibitor INCB018424: therapeutic implications for the treatment of myeloproliferative neoplasms. Blood 115(15): 3109-3117.
-
(2010)
Blood
, vol.115
, Issue.15
, pp. 3109-3117
-
-
Quintás-Cardama, A.1
Vaddi, K.2
Liu, P.3
-
10
-
-
84861806284
-
The effect of CYP3A4 inhibition or induction on the pharmacokinetics and pharmacodynamics of orally administered ruxolitinib (INCB018424 phosphate) in healthy volunteers
-
Shi JG, Chen X, Emm T et al (2012) The effect of CYP3A4 inhibition or induction on the pharmacokinetics and pharmacodynamics of orally administered ruxolitinib (INCB018424 phosphate) in healthy volunteers. J Clin Pharmacol 52(6): 809-818.
-
(2012)
J Clin Pharmacol
, vol.52
, Issue.6
, pp. 809-818
-
-
Shi, J.G.1
Chen, X.2
Emm, T.3
-
11
-
-
78049412594
-
Metabolism, excretion, and pharmacokinetics of [14C] INCB018424, a selective Janus tyrosine kinase 1/2 inhibitor, in humans
-
Shilling AD, Nedza FM, Emm T et al (2010) Metabolism, excretion, and pharmacokinetics of [14C] INCB018424, a selective Janus tyrosine kinase 1/2 inhibitor, in humans. Drug Metab Dispos 38(11): 2023-2031.
-
(2010)
Drug Metab Dispos
, vol.38
, Issue.11
, pp. 2023-2031
-
-
Shilling, A.D.1
Nedza, F.M.2
Emm, T.3
-
12
-
-
84940996598
-
Preliminary safety and efficacy from a phase II stud of ruxolitinib in patients with primary and secondary myelofibrosis with platelet counts of 50-100 9 109/L
-
(abstract 0597)
-
Talpaz M, Hamburg SI, Jamieson K et al (2012a) Preliminary safety and efficacy from a phase II stud of ruxolitinib in patients with primary and secondary myelofibrosis with platelet counts of 50-100 9 109/L. Haematologica 97(s1): 245 (abstract 0597).
-
(2012)
Haematologica
, vol.97
, Issue.S1
-
-
Talpaz, M.1
Hamburg, S.I.2
Jamieson, K.3
-
14
-
-
83155182714
-
Serious adverse events during ruxolitinib treatment discontinuation in patients with myelofibrosis
-
Tefferi A, Pardanani A (2011) Serious adverse events during ruxolitinib treatment discontinuation in patients with myelofibrosis. Mayo Clin Proc 86(12): 1188-1191.
-
(2011)
Mayo Clin Proc
, vol.86
, Issue.12
, pp. 1188-1191
-
-
Tefferi, A.1
Pardanani, A.2
-
15
-
-
80054028202
-
Long-term outcome of treatment with ruxolitinib in myelofibrosis
-
Tefferi A, Litzow MR, Pardanani A (2011) Long-term outcome of treatment with ruxolitinib in myelofibrosis. N Engl J Med 365(15): 1455-1457.
-
(2011)
N Engl J Med
, vol.365
, Issue.15
, pp. 1455-1457
-
-
Tefferi, A.1
Litzow, M.R.2
Pardanani, A.3
-
16
-
-
84890476619
-
Long-term outcomes from a phase 3 study comparing ruxolitinib with best available therapy (BAT) for the treatment of myelofibrosis (MF): A 3-year update of COMFORT-II
-
(abstract S1111)
-
Vannucchi A, Cervantes F, Niederwieser D et al (2013) Long-term outcomes from a phase 3 study comparing ruxolitinib with best available therapy (BAT) for the treatment of myelofibrosis (MF): a 3-year update of COMFORT-II. Haematologica 98(s1): 456 (abstract S1111).
-
(2013)
Haematologica
, vol.98
, Issue.S1
-
-
Vannucchi, A.1
Cervantes, F.2
Niederwieser, D.3
-
17
-
-
77956696835
-
Safety and efficacy of INCB018424, a JAK1 and JAK2 inhibitor, in myelofibrosis
-
Verstovsek S, Kantarjian H, Mesa RA et al (2010) Safety and efficacy of INCB018424, a JAK1 and JAK2 inhibitor, in myelofibrosis. N Engl J Med 363(12): 1117-1127.
-
(2010)
N Engl J Med
, vol.363
, Issue.12
, pp. 1117-1127
-
-
Verstovsek, S.1
Kantarjian, H.2
Mesa, R.A.3
-
18
-
-
84865192181
-
Long-term outcomes of 107 patients with myelofibrosis receiving JAK1/JAK2 inhibitor ruxolitinib: Survival advantage in comparison to matched historical controls
-
Verstovsek S, Kantarjian HM, Estrov Z et al (2012a) Long-term outcomes of 107 patients with myelofibrosis receiving JAK1/JAK2 inhibitor ruxolitinib: survival advantage in comparison to matched historical controls. Blood 120(6): 1202-1209.
-
(2012)
Blood
, vol.120
, Issue.6
, pp. 1202-1209
-
-
Verstovsek, S.1
Kantarjian, H.M.2
Estrov, Z.3
-
19
-
-
84863393110
-
A double-blind, placebo-controlled trial of ruxolitinib for myelofibrosis
-
Verstovsek S, Mesa RA, Gotlib J et al (2012b) A double-blind, placebo-controlled trial of ruxolitinib for myelofibrosis. N Engl J Med 366(9): 799-807.
-
(2012)
N Engl J Med
, vol.366
, Issue.9
, pp. 799-807
-
-
Verstovsek, S.1
Mesa, R.A.2
Gotlib, J.3
-
20
-
-
84940979887
-
-
Blood 120 (abstract 800) (ASH Annual Meeting Abstracts)
-
Verstovsek S, Mesa RA, Gotlib J, et al (2012c) Long-term outcome of ruxolitinib treatment in patients with myelofibrosis: durable reductions in spleen volume, improvements in quality of life, and overall survival advantage in COMFORT-I. Blood 120 (abstract 800) (ASH Annual Meeting Abstracts).
-
(2012)
Long-term outcome of ruxolitinib treatment in patients with myelofibrosis: Durable reductions in spleen volume, improvements in quality of life, and overall survival advantage in COMFORT-I
-
-
Verstovsek, S.1
Mesa, R.A.2
Gotlib, J.3
-
21
-
-
84876790720
-
The clinical benefit of ruxolitinib across patient subgroups: Analysis of a placebo-controlled, Phase III study in patients with myelofibrosis
-
Verstovsek S, Mesa RA, Gotlib J et al (2013) The clinical benefit of ruxolitinib across patient subgroups: analysis of a placebo-controlled, Phase III study in patients with myelofibrosis. Br J Haematol 161(4): 508-516.
-
(2013)
Br J Haematol
, vol.161
, Issue.4
, pp. 508-516
-
-
Verstovsek, S.1
Mesa, R.A.2
Gotlib, J.3
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