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Volumn 201, Issue , 2014, Pages 249-257

Ruxolitinib

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450 3A4; ERYTHROMYCIN; ERYTHROPOIETIN; GLUCOCORTICOID; HYDROXYUREA; INTERLEUKIN 6; JANUS KINASE 1; JANUS KINASE 2; KETOCONAZOLE; LEPTIN; PLACEBO; RIFAMPICIN; RUXOLITINIB; STAT3 PROTEIN; TUMOR NECROSIS FACTOR ALPHA; PROTEIN KINASE INHIBITOR; PYRAZOLE DERIVATIVE;

EID: 84905818825     PISSN: 00800015     EISSN: 21976767     Source Type: Book Series    
DOI: 10.1007/978-3-642-54490-3_16     Document Type: Article
Times cited : (22)

References (21)
  • 1
    • 63849328927 scopus 로고    scopus 로고
    • New prognostic scoring system for primary myelofibrosis based on a study of the International Working Group for Myelofibrosis Research and Treatment
    • Cervantes F, Dupriez B, Pereira A et al (2009) New prognostic scoring system for primary myelofibrosis based on a study of the International Working Group for Myelofibrosis Research and Treatment. Blood 113(13): 2895-2901.
    • (2009) Blood , vol.113 , Issue.13 , pp. 2895-2901
    • Cervantes, F.1    Dupriez, B.2    Pereira, A.3
  • 2
    • 84857837774 scopus 로고    scopus 로고
    • JAK inhibition with ruxolitinib versus best available therapy for myelofibrosis
    • Harrison C, Kiladjian JJ, Al-Ali HK et al (2012a) JAK inhibition with ruxolitinib versus best available therapy for myelofibrosis. N Engl J Med 366(9): 787-798.
    • (2012) N Engl J Med , vol.366 , Issue.9 , pp. 787-798
    • Harrison, C.1    Kiladjian, J.J.2    Al-Ali, H.K.3
  • 4
    • 17844383458 scopus 로고    scopus 로고
    • A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera
    • James C, Ugo V, Le Couédic JP et al (2005) A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera. Nature 434(7037): 1144-1148.
    • (2005) Nature , vol.434 , Issue.7037 , pp. 1144-1148
    • James, C.1    Ugo, V.2    Le Couédic, J.P.3
  • 5
    • 84880252493 scopus 로고    scopus 로고
    • A comprehensive review and analysis of the effect of ruxolitinib therapy on the survival of patients with myelofibrosis
    • Mascarenhas J, Hoffman R (2013) A comprehensive review and analysis of the effect of ruxolitinib therapy on the survival of patients with myelofibrosis. Blood 121(24): 4832-4837.
    • (2013) Blood , vol.121 , Issue.24 , pp. 4832-4837
    • Mascarenhas, J.1    Hoffman, R.2
  • 6
    • 35548944961 scopus 로고    scopus 로고
    • SnapShot: JAK-STAT signaling
    • Mertens C, Darnell JE Jr (2007) SnapShot: JAK-STAT signaling. Cell 131(3): 612.
    • (2007) Cell , vol.131 , Issue.3 , pp. 612
    • Mertens, C.1    Darnell, J.E.2
  • 8
    • 84876082159 scopus 로고    scopus 로고
    • Effect of ruxolitinib therapy on myelofibrosis-related symptoms and other patient-reported outcomes in COMFORT-I: A randomized, double-blind, placebo-controlled trial
    • Mesa RA, Gotlib J, Gupta V et al (2013) Effect of ruxolitinib therapy on myelofibrosis-related symptoms and other patient-reported outcomes in COMFORT-I: a randomized, double-blind, placebo-controlled trial. J Clin Oncol 31(10): 1285-1292.
    • (2013) J Clin Oncol , vol.31 , Issue.10 , pp. 1285-1292
    • Mesa, R.A.1    Gotlib, J.2    Gupta, V.3
  • 9
    • 77950684805 scopus 로고    scopus 로고
    • Preclinical characterization of the selective JAK1/2 inhibitor INCB018424: Therapeutic implications for the treatment of myeloproliferative neoplasms
    • Quintás-Cardama A, Vaddi K, Liu P et al (2010) Preclinical characterization of the selective JAK1/2 inhibitor INCB018424: therapeutic implications for the treatment of myeloproliferative neoplasms. Blood 115(15): 3109-3117.
    • (2010) Blood , vol.115 , Issue.15 , pp. 3109-3117
    • Quintás-Cardama, A.1    Vaddi, K.2    Liu, P.3
  • 10
    • 84861806284 scopus 로고    scopus 로고
    • The effect of CYP3A4 inhibition or induction on the pharmacokinetics and pharmacodynamics of orally administered ruxolitinib (INCB018424 phosphate) in healthy volunteers
    • Shi JG, Chen X, Emm T et al (2012) The effect of CYP3A4 inhibition or induction on the pharmacokinetics and pharmacodynamics of orally administered ruxolitinib (INCB018424 phosphate) in healthy volunteers. J Clin Pharmacol 52(6): 809-818.
    • (2012) J Clin Pharmacol , vol.52 , Issue.6 , pp. 809-818
    • Shi, J.G.1    Chen, X.2    Emm, T.3
  • 11
    • 78049412594 scopus 로고    scopus 로고
    • Metabolism, excretion, and pharmacokinetics of [14C] INCB018424, a selective Janus tyrosine kinase 1/2 inhibitor, in humans
    • Shilling AD, Nedza FM, Emm T et al (2010) Metabolism, excretion, and pharmacokinetics of [14C] INCB018424, a selective Janus tyrosine kinase 1/2 inhibitor, in humans. Drug Metab Dispos 38(11): 2023-2031.
    • (2010) Drug Metab Dispos , vol.38 , Issue.11 , pp. 2023-2031
    • Shilling, A.D.1    Nedza, F.M.2    Emm, T.3
  • 12
    • 84940996598 scopus 로고    scopus 로고
    • Preliminary safety and efficacy from a phase II stud of ruxolitinib in patients with primary and secondary myelofibrosis with platelet counts of 50-100 9 109/L
    • (abstract 0597)
    • Talpaz M, Hamburg SI, Jamieson K et al (2012a) Preliminary safety and efficacy from a phase II stud of ruxolitinib in patients with primary and secondary myelofibrosis with platelet counts of 50-100 9 109/L. Haematologica 97(s1): 245 (abstract 0597).
    • (2012) Haematologica , vol.97 , Issue.S1
    • Talpaz, M.1    Hamburg, S.I.2    Jamieson, K.3
  • 14
    • 83155182714 scopus 로고    scopus 로고
    • Serious adverse events during ruxolitinib treatment discontinuation in patients with myelofibrosis
    • Tefferi A, Pardanani A (2011) Serious adverse events during ruxolitinib treatment discontinuation in patients with myelofibrosis. Mayo Clin Proc 86(12): 1188-1191.
    • (2011) Mayo Clin Proc , vol.86 , Issue.12 , pp. 1188-1191
    • Tefferi, A.1    Pardanani, A.2
  • 15
    • 80054028202 scopus 로고    scopus 로고
    • Long-term outcome of treatment with ruxolitinib in myelofibrosis
    • Tefferi A, Litzow MR, Pardanani A (2011) Long-term outcome of treatment with ruxolitinib in myelofibrosis. N Engl J Med 365(15): 1455-1457.
    • (2011) N Engl J Med , vol.365 , Issue.15 , pp. 1455-1457
    • Tefferi, A.1    Litzow, M.R.2    Pardanani, A.3
  • 16
    • 84890476619 scopus 로고    scopus 로고
    • Long-term outcomes from a phase 3 study comparing ruxolitinib with best available therapy (BAT) for the treatment of myelofibrosis (MF): A 3-year update of COMFORT-II
    • (abstract S1111)
    • Vannucchi A, Cervantes F, Niederwieser D et al (2013) Long-term outcomes from a phase 3 study comparing ruxolitinib with best available therapy (BAT) for the treatment of myelofibrosis (MF): a 3-year update of COMFORT-II. Haematologica 98(s1): 456 (abstract S1111).
    • (2013) Haematologica , vol.98 , Issue.S1
    • Vannucchi, A.1    Cervantes, F.2    Niederwieser, D.3
  • 17
    • 77956696835 scopus 로고    scopus 로고
    • Safety and efficacy of INCB018424, a JAK1 and JAK2 inhibitor, in myelofibrosis
    • Verstovsek S, Kantarjian H, Mesa RA et al (2010) Safety and efficacy of INCB018424, a JAK1 and JAK2 inhibitor, in myelofibrosis. N Engl J Med 363(12): 1117-1127.
    • (2010) N Engl J Med , vol.363 , Issue.12 , pp. 1117-1127
    • Verstovsek, S.1    Kantarjian, H.2    Mesa, R.A.3
  • 18
    • 84865192181 scopus 로고    scopus 로고
    • Long-term outcomes of 107 patients with myelofibrosis receiving JAK1/JAK2 inhibitor ruxolitinib: Survival advantage in comparison to matched historical controls
    • Verstovsek S, Kantarjian HM, Estrov Z et al (2012a) Long-term outcomes of 107 patients with myelofibrosis receiving JAK1/JAK2 inhibitor ruxolitinib: survival advantage in comparison to matched historical controls. Blood 120(6): 1202-1209.
    • (2012) Blood , vol.120 , Issue.6 , pp. 1202-1209
    • Verstovsek, S.1    Kantarjian, H.M.2    Estrov, Z.3
  • 19
    • 84863393110 scopus 로고    scopus 로고
    • A double-blind, placebo-controlled trial of ruxolitinib for myelofibrosis
    • Verstovsek S, Mesa RA, Gotlib J et al (2012b) A double-blind, placebo-controlled trial of ruxolitinib for myelofibrosis. N Engl J Med 366(9): 799-807.
    • (2012) N Engl J Med , vol.366 , Issue.9 , pp. 799-807
    • Verstovsek, S.1    Mesa, R.A.2    Gotlib, J.3
  • 21
    • 84876790720 scopus 로고    scopus 로고
    • The clinical benefit of ruxolitinib across patient subgroups: Analysis of a placebo-controlled, Phase III study in patients with myelofibrosis
    • Verstovsek S, Mesa RA, Gotlib J et al (2013) The clinical benefit of ruxolitinib across patient subgroups: analysis of a placebo-controlled, Phase III study in patients with myelofibrosis. Br J Haematol 161(4): 508-516.
    • (2013) Br J Haematol , vol.161 , Issue.4 , pp. 508-516
    • Verstovsek, S.1    Mesa, R.A.2    Gotlib, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.