A case of thrombotic microangiopathy associated with antiphospholipid antibody syndrome successfully treated with eculizumab

Transplantation

Volumn 98, Issue 3, 2014, Pages

  Bakhtar, Omid ^a   Thajudeen, Bijin ^a   Braunhut, Beth L ^b   Yost, Sarah E ^a   Bracamonte, Erika R ^b   Sussman, Amy N ^a   Kaplan, Bruce ^c  

^a UNIVERSITY OF ARIZONA   (United States)

^b UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

^c UNIVERSITY OF KANSAS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CREATININE; ECULIZUMAB; MYCOPHENOLIC ACID; PREDNISONE; TACROLIMUS; THYMOCYTE ANTIBODY;

ABDOMINAL DISCOMFORT; ABDOMINAL TENDERNESS; ABNORMAL FECES; ADULT; ANTIPHOSPHOLIPID SYNDROME; CASE REPORT; ENDOCARDITIS; HISTOPATHOLOGY; HOSPITAL ADMISSION; HUMAN; IMMUNOFLUORESCENCE MICROSCOPY; IMMUNOSUPPRESSIVE TREATMENT; INTRAVASCULAR HEMOLYSIS; KIDNEY BIOPSY; KIDNEY DONOR; LETTER; LIVING DONOR; LUPUS ERYTHEMATOSUS NEPHRITIS; MALE; MEDICAL HISTORY; MITRAL VALVE REPLACEMENT; OUTCOME ASSESSMENT; PHYSICAL EXAMINATION; PLASMAPHERESIS; PRIORITY JOURNAL; THROMBOCYTOPENIA; THROMBOTIC THROMBOCYTOPENIC PURPURA; VOMITING;

ADULT; ANTIBODIES, MONOCLONAL, HUMANIZED; ANTIPHOSPHOLIPID SYNDROME; HUMANS; MALE; THROMBOTIC MICROANGIOPATHIES;

EID: 84905733420     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/TP.0000000000000267     Document Type: Letter

References (5)

1. Moroni G, Ventura D, Riva P, et al. Antiphospholipid antibodies are associated with an increased risk for chronic renal insufficiency in patients with lupus nephritis. Am J Kidney Dis 2004; 43: 28.
2. Canaud G, Bienaimé F, Noël LH, et al. Severe vascular lesions and poor functional outcome in kidney transplant recipients with lupus anticoagulant antibodies. Am J Transplant 2010; 10: 2051.
3. Pierangeli SS, Girardi G, Vega-Ostertag M, et al. Requirement of activation of complement C3 and C5 for antiphospholipid antibody-mediated thrombophilia. Arthritis Rheum 2005; 52: 2120.
4. Lonze BE, Zachary AA, Magro CM, et al. Eculizumab prevents recurrent antiphospholipid antibody syndrome and enables successful renal transplantation. Am J Transplant 2014; 14: 459.
5. Ponticelli C, Banfi G. Thrombotic microangiopathy after kidney transplantation. Transpl Int 2006; 19: 789.