메뉴 건너뛰기




Volumn , Issue , 2008, Pages 219-236

Increased cortical excitability as a critical element in schizophrenia pathophysiology

Author keywords

[No Author keywords available]

Indexed keywords


EID: 84905718184     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-0-387-74351-6_11     Document Type: Chapter
Times cited : (9)

References (120)
  • 4
  • 5
    • 0035869617 scopus 로고    scopus 로고
    • Delayed onset of enhanced MK-801-induced motor hyperactivity after neonatal lesions of the rat ventral hippocampus
    • Al-Amin HA, Shannon Weickert C, Weinberger DR, Lipska BK (2001) Delayed onset of enhanced MK-801-induced motor hyperactivity after neonatal lesions of the rat ventral hippocampus. Biol Psychiatry 49:528-539.
    • (2001) Biol Psychiatry , vol.49 , pp. 528-539
    • Al-Amin, H.A.1    Shannon Weickert, C.2    Weinberger, D.R.3    Lipska, B.K.4
  • 7
    • 0028988518 scopus 로고
    • Synchronous development of pyramidal neuron dendritic spines and parvalbumin-immunoreactive chandelier neuron axon terminals in layer III of monkey prefrontal cortex
    • Anderson SA, Classey JD, Conde F, Lund JS, Lewis DA (1995) Synchronous development of pyramidal neuron dendritic spines and parvalbumin-immunoreactive chandelier neuron axon terminals in layer III of monkey prefrontal cortex. Neuroscience 67:7-22.
    • (1995) Neuroscience , vol.67 , pp. 7-22
    • Anderson, S.A.1    Classey, J.D.2    Conde, F.3    Lund, J.S.4    Lewis, D.A.5
  • 8
    • 0025915446 scopus 로고
    • Some cytoarchitectural abnormalities of the entorhinal cortex in schizophrenia
    • Arnold SE, Hyman BT, Van Hoesen GW, Damasio AR (1991) Some cytoarchitectural abnormalities of the entorhinal cortex in schizophrenia. Arch Gen Psychiat 48:625-632.
    • (1991) Arch Gen Psychiat , vol.48 , pp. 625-632
    • Arnold, S.E.1    Hyman, B.T.2    Van Hoesen, G.W.3    Damasio, A.R.4
  • 9
    • 0037159638 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor (BDNF) mRNA in rats with neonatal ibotenic acid lesions of the ventral hippocampus
    • Ashe PC, Chlan-Fourney J, Juorio AV, Li XM (2002) Brain-derived neurotrophic factor (BDNF) mRNA in rats with neonatal ibotenic acid lesions of the ventral hippocampus. Brain Res 956:126-135.
    • (2002) Brain Res , vol.956 , pp. 126-135
    • Ashe, P.C.1    Chlan-Fourney, J.2    Juorio, A.V.3    Li, X.M.4
  • 10
    • 0442292274 scopus 로고    scopus 로고
    • Expression of Disrupted-In-Schizophrenia-1, a schizophrenia-associated gene, is prominent in the mouse hippocampus throughout brain development
    • Austin CP, Ky B, Ma L, Morris JA, Shughrue PJ (2004) Expression of Disrupted-In-Schizophrenia-1, a schizophrenia-associated gene, is prominent in the mouse hippocampus throughout brain development. Neuroscience 124:3-10.
    • (2004) Neuroscience , vol.124 , pp. 3-10
    • Austin, C.P.1    Ky, B.2    Ma, L.3    Morris, J.A.4    Shughrue, P.J.5
  • 11
    • 0032765151 scopus 로고    scopus 로고
    • Memory and socioemotional behavior in monkeys after hippocampal damage incurred in infancy or in adulthood
    • Bachevalier J, Alvarado MC, Malkova L (1999) Memory and socioemotional behavior in monkeys after hippocampal damage incurred in infancy or in adulthood. Biol Psychiat 46:329-339.
    • (1999) Biol Psychiat , vol.46 , pp. 329-339
    • Bachevalier, J.1    Alvarado, M.C.2    Malkova, L.3
  • 12
    • 0031466522 scopus 로고    scopus 로고
    • Measurement of glutamate and glutamine in the medial prefrontal cortex of never-treated schizophrenic patients and healthy controls by proton magnetic resonance spectroscopy
    • Bartha R, Williamson PC, Drost DJ, Malla A, Carr TJ, Cortese L, Canaran G, Rylett RJ, Neufeld RW (1997) Measurement of glutamate and glutamine in the medial prefrontal cortex of never-treated schizophrenic patients and healthy controls by proton magnetic resonance spectroscopy. Arch Gen Psychiatry 54:959-965.
    • (1997) Arch Gen Psychiatry , vol.54 , pp. 959-965
    • Bartha, R.1    Williamson, P.C.2    Drost, D.J.3    Malla, A.4    Carr, T.J.5    Cortese, L.6    Canaran, G.7    Rylett, R.J.8    Neufeld, R.W.9
  • 13
    • 0030947083 scopus 로고    scopus 로고
    • Parvalbumin-immunoreactive neurons are reduced in the prefrontal cortex of schizophrenics
    • Beasley CL, Reynolds GP (1997) Parvalbumin-immunoreactive neurons are reduced in the prefrontal cortex of schizophrenics. Schizophr Res 24:349-355.
    • (1997) Schizophr Res , vol.24 , pp. 349-355
    • Beasley, C.L.1    Reynolds, G.P.2
  • 14
    • 0030800056 scopus 로고    scopus 로고
    • The role of stress and dopamine-GABA interactions in the vulnerability for schizophrenia
    • Benes FM (1997) The role of stress and dopamine-GABA interactions in the vulnerability for schizophrenia. J Psychiatr Res 31:257-275.
    • (1997) J Psychiatr Res , vol.31 , pp. 257-275
    • Benes, F.M.1
  • 15
    • 0032778735 scopus 로고    scopus 로고
    • Evidence for altered trisynaptic circuitry in schizophrenic hippocampus
    • Benes FM (1999) Evidence for altered trisynaptic circuitry in schizophrenic hippocampus. Biol Psychiatry 46:589-599.
    • (1999) Biol Psychiatry , vol.46 , pp. 589-599
    • Benes, F.M.1
  • 16
    • 0022579449 scopus 로고
    • Physiologic dysfunction of dorsolateral prefrontal cortex in schizophrenia. II. Role of neuroleptic treatment, attention, and mental effort
    • Berman KF, Zec RF, Weinberger DR (1986) Physiologic dysfunction of dorsolateral prefrontal cortex in schizophrenia. II. Role of neuroleptic treatment, attention, and mental effort. Arch Gen Psychiat 43:126-135.
    • (1986) Arch Gen Psychiat , vol.43 , pp. 126-135
    • Berman, K.F.1    Zec, R.F.2    Weinberger, D.R.3
  • 17
    • 0033549254 scopus 로고    scopus 로고
    • Neonatal ventral hippocampal lesions attenuate the nucleus accumbens dopamine response to stress: An electrochemical study in the adult rat
    • Brake WG, Sullivan RM, Flores G, Srivastava L, Gratton A (1999) Neonatal ventral hippocampal lesions attenuate the nucleus accumbens dopamine response to stress: an electrochemical study in the adult rat. Brain Res 831:25-32.
    • (1999) Brain Res , vol.831 , pp. 25-32
    • Brake, W.G.1    Sullivan, R.M.2    Flores, G.3    Srivastava, L.4    Gratton, A.5
  • 18
    • 0027991388 scopus 로고
    • The molecular basis of NMDA receptor subtypes: Native receptor diversity is predicted by subunit composition
    • Buller AL, Larson HC, Schneider BE, Beaton JA, Morrisett RA, Monaghan DT (1994) The molecular basis of NMDA receptor subtypes: native receptor diversity is predicted by subunit composition. J Neurosci 14:5471-5484.
    • (1994) J Neurosci , vol.14 , pp. 5471-5484
    • Buller, A.L.1    Larson, H.C.2    Schneider, B.E.3    Beaton, J.A.4    Morrisett, R.A.5    Monaghan, D.T.6
  • 19
  • 25
    • 0036900019 scopus 로고    scopus 로고
    • Motivational responses to natural and drug rewards in rats with neonatal ventral hippocampal lesions: An animal model of dual diagnosis schizophrenia
    • Chambers RA, Self DW (2002) Motivational responses to natural and drug rewards in rats with neonatal ventral hippocampal lesions: an animal model of dual diagnosis schizophrenia. Neuropsychopharmacology 27:889-905.
    • (2002) Neuropsychopharmacology , vol.27 , pp. 889-905
    • Chambers, R.A.1    Self, D.W.2
  • 26
    • 0030561083 scopus 로고    scopus 로고
    • Cognitive effects of neonatal hippocampal lesions in a rat model of schizophrenia
    • Chambers RA, Moore J, McEvoy JP, Levin ED (1996) Cognitive effects of neonatal hippocampal lesions in a rat model of schizophrenia. Neuropsychopharmacol 15:587-594.
    • (1996) Neuropsychopharmacol , vol.15 , pp. 587-594
    • Chambers, R.A.1    Moore, J.2    McEvoy, J.P.3    Levin, E.D.4
  • 28
    • 0024418234 scopus 로고
    • A quantitative investigation of hippocampal pyramidal cell size, shape and variability of orientation in schizophrenia
    • Christison GW, Casanova MF, Weinberger DR, Rawlings R (1989) A quantitative investigation of hippocampal pyramidal cell size, shape and variability of orientation in schizophrenia. Arch Gen Psychiat 46:1027-1032.
    • (1989) Arch Gen Psychiat , vol.46 , pp. 1027-1032
    • Christison, G.W.1    Casanova, M.F.2    Weinberger, D.R.3    Rawlings, R.4
  • 29
    • 3142737856 scopus 로고    scopus 로고
    • The NMDA receptor glycine modulatory site: A therapeutic target for improving cognition and reducing negative symptoms in schizophrenia
    • Coyle JT, Tsai G (2004) The NMDA receptor glycine modulatory site: a therapeutic target for improving cognition and reducing negative symptoms in schizophrenia. Psychopharmacology (Berl) 174:32-38.
    • (2004) Psychopharmacology (Berl) , vol.174 , pp. 32-38
    • Coyle, J.T.1    Tsai, G.2
  • 30
    • 0037064445 scopus 로고    scopus 로고
    • Amygdalo-cortical sprouting continues into early adulthood: Implications for the development of normal and abnormal function during adolescence
    • Cunningham MG, Bhattacharyya S, Benes FM (2002) Amygdalo-cortical sprouting continues into early adulthood: implications for the development of normal and abnormal function during adolescence. J Comp Neurol 453:116-130.
    • (2002) J Comp Neurol , vol.453 , pp. 116-130
    • Cunningham, M.G.1    Bhattacharyya, S.2    Benes, F.M.3
  • 32
    • 3042613492 scopus 로고    scopus 로고
    • Irreversible loss of a subpopulation of cortical interneurons in the absence of glutamatergic network activity
    • de Lima AD, Opitz T, Voigt T (2004) Irreversible loss of a subpopulation of cortical interneurons in the absence of glutamatergic network activity. Eur J Neurosci 19:2931-2943.
    • (2004) Eur J Neurosci , vol.19 , pp. 2931-2943
    • De Lima, A.D.1    Opitz, T.2    Voigt, T.3
  • 34
    • 0029851271 scopus 로고    scopus 로고
    • Regional and ontogenic expression of the NMDA receptor subunit NR2D protein in rat brain using a subunit-specific antibody
    • Dunah AW, Yasuda RP, Wang YH, Luo J, Davila-Garcia M, Gbadegesin M, Vicini S, Wolfe BB (1996) Regional and ontogenic expression of the NMDA receptor subunit NR2D protein in rat brain using a subunit-specific antibody. J Neurochem 67:2335-2345.
    • (1996) J Neurochem , vol.67 , pp. 2335-2345
    • Dunah, A.W.1    Yasuda, R.P.2    Wang, Y.H.3    Luo, J.4    Davila-Garcia, M.5    Gbadegesin, M.6    Vicini, S.7    Wolfe, B.B.8
  • 35
    • 0032101622 scopus 로고    scopus 로고
    • Hippocampal and cortical growth-associated protein-43 messenger RNA in schizophrenia
    • Eastwood SL, Harrison PJ (1998) Hippocampal and cortical growth-associated protein-43 messenger RNA in schizophrenia. Neuroscience 86:437-448.
    • (1998) Neuroscience , vol.86 , pp. 437-448
    • Eastwood, S.L.1    Harrison, P.J.2
  • 36
    • 11844304923 scopus 로고    scopus 로고
    • Decreased expression of vesicular glutamate transporter 1 and complexin II mRNAs in schizophrenia: Further evidence for a synaptic pathology affecting glutamate neurons
    • Eastwood SL, Harrison PJ (2005) Decreased expression of vesicular glutamate transporter 1 and complexin II mRNAs in schizophrenia: further evidence for a synaptic pathology affecting glutamate neurons. Schizophr Res 73:159-172.
    • (2005) Schizophr Res , vol.73 , pp. 159-172
    • Eastwood, S.L.1    Harrison, P.J.2
  • 37
    • 0028965594 scopus 로고
    • Altered synaptophisin expression as a marker of synaptic pathology in schizophrenia
    • Eastwood SL, Burnet PWJ, Harrison PJ (1995) Altered synaptophisin expression as a marker of synaptic pathology in schizophrenia. Neuroscience 66:309-319.
    • (1995) Neuroscience , vol.66 , pp. 309-319
    • Eastwood, S.L.1    Burnet, P.W.J.2    Harrison, P.J.3
  • 38
    • 16844363904 scopus 로고    scopus 로고
    • Decreased hippocampal expression of the susceptibility gene PPP3CC and other calcineurin subunits in schizophrenia
    • Eastwood SL, Burnet PW, Harrison PJ (2005) Decreased hippocampal expression of the susceptibility gene PPP3CC and other calcineurin subunits in schizophrenia. Biol Psychiatry 57:702-710.
    • (2005) Biol Psychiatry , vol.57 , pp. 702-710
    • Eastwood, S.L.1    Burnet, P.W.2    Harrison, P.J.3
  • 41
    • 8444245975 scopus 로고    scopus 로고
    • Disruption of neurogenesis on gestational day 17 in the rat causes behavioral changes relevant to positive and negative schizophrenia symptoms and alters amphetamine-induced dopamine release in nucleus accumbens
    • Flagstad P, Mork A, Glenthoj BY, van Beek J, Michael-Titus AT, Didriksen M (2004) Disruption of neurogenesis on gestational day 17 in the rat causes behavioral changes relevant to positive and negative schizophrenia symptoms and alters amphetamine-induced dopamine release in nucleus accumbens. Neuropsychopharmacology 29:2052-2064.
    • (2004) Neuropsychopharmacology , vol.29 , pp. 2052-2064
    • Flagstad, P.1    Mork, A.2    Glenthoj, B.Y.3    Van Beek, J.4    Michael-Titus, A.T.5    Didriksen, M.6
  • 42
    • 19444372194 scopus 로고    scopus 로고
    • Alterations in dendritic morphology of prefrontal cortical and nucleus accumbens neurons in post-pubertal rats after neonatal excitotoxic lesions of the ventral hippocampus
    • Flores G, Alquicer G, Silva-Gomez AB, Zaldivar G, Stewart J, Quirion R, Srivastava LK (2005) Alterations in dendritic morphology of prefrontal cortical and nucleus accumbens neurons in post-pubertal rats after neonatal excitotoxic lesions of the ventral hippocampus. Neuroscience 133:463-470.
    • (2005) Neuroscience , vol.133 , pp. 463-470
    • Flores, G.1    Alquicer, G.2    Silva-Gomez, A.B.3    Zaldivar, G.4    Stewart, J.5    Quirion, R.6    Srivastava, L.K.7
  • 43
    • 0037418319 scopus 로고    scopus 로고
    • Selective modulation of excitatory and inhibitory microcircuits by dopamine
    • Gao WJ, Goldman-Rakic PS (2003) Selective modulation of excitatory and inhibitory microcircuits by dopamine. Proc Natl Acad Sci USA 100:2836-2841.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 2836-2841
    • Gao, W.J.1    Goldman-Rakic, P.S.2
  • 44
    • 0033985644 scopus 로고    scopus 로고
    • Decreased dendritic spine density on prefrontal cortical pyramidal neurons in schizophrenia
    • Glantz LA, Lewis DA (2000) Decreased dendritic spine density on prefrontal cortical pyramidal neurons in schizophrenia. Arch Gen Psychiatry 57:65-73.
    • (2000) Arch Gen Psychiatry , vol.57 , pp. 65-73
    • Glantz, L.A.1    Lewis, D.A.2
  • 45
    • 0033026679 scopus 로고    scopus 로고
    • Expression of TrkB and TrkC but not BDNF mRNA in neurochemically identified interneurons in rat visual cortex in vivo and in organotypic cultures
    • Gorba T, Wahle P (1999) Expression of TrkB and TrkC but not BDNF mRNA in neurochemically identified interneurons in rat visual cortex in vivo and in organotypic cultures. Eur J Neurosci 11:1179-1190.
    • (1999) Eur J Neurosci , vol.11 , pp. 1179-1190
    • Gorba, T.1    Wahle, P.2
  • 46
    • 0037109739 scopus 로고    scopus 로고
    • Delayed mesolimbic system alteration in a developmental animal model of schizophrenia
    • Goto Y, O'Donnell P (2002) Delayed mesolimbic system alteration in a developmental animal model of schizophrenia. J Neurosci 22:9070-9077.
    • (2002) J Neurosci , vol.22 , pp. 9070-9077
    • Goto, Y.1    O'Donnell, P.2
  • 47
    • 1442357659 scopus 로고    scopus 로고
    • Prefrontal lesion reverses abnormal mesoaccumbens response in an animal model of schizophrenia
    • Goto Y, O'Donnell P (2004) Prefrontal lesion reverses abnormal mesoaccumbens response in an animal model of schizophrenia. Biol Psychiatry 55:172-176.
    • (2004) Biol Psychiatry , vol.55 , pp. 172-176
    • Goto, Y.1    O'Donnell, P.2
  • 48
    • 0026059697 scopus 로고
    • Phasic versus tonic dopamine release and the modulation of dopamine system responsivity: A hypothesis for the etiology of schizophrenia
    • Grace AA (1991) Phasic versus tonic dopamine release and the modulation of dopamine system responsivity: A hypothesis for the etiology of schizophrenia. Neuroscience 41:1-24.
    • (1991) Neuroscience , vol.41 , pp. 1-24
    • Grace, A.A.1
  • 50
    • 2342538196 scopus 로고    scopus 로고
    • The hippocampus in schizophrenia: A review of the neuropathological evidence and its pathophysiological implications
    • Harrison PJ (2004) The hippocampus in schizophrenia: a review of the neuropathological evidence and its pathophysiological implications. Psychopharmacology (Berl) 174:151-162.
    • (2004) Psychopharmacology (Berl) , vol.174 , pp. 151-162
    • Harrison, P.J.1
  • 51
    • 0032556365 scopus 로고    scopus 로고
    • Preferential involvement of excitatory neurons in medial temporal lobe in schizophrenia
    • Harrison PJ, Eastwood SL (1998) Preferential involvement of excitatory neurons in medial temporal lobe in schizophrenia. Lancet 352:1669-1673.
    • (1998) Lancet , vol.352 , pp. 1669-1673
    • Harrison, P.J.1    Eastwood, S.L.2
  • 52
    • 6344252204 scopus 로고    scopus 로고
    • Schizophrenia genes, gene expression, and neuropathology: On the matter of their convergence
    • Harrison PJ, Weinberger DR (2004) Schizophrenia genes, gene expression, and neuropathology: on the matter of their convergence. Mol Psychiatry.
    • (2004) Mol Psychiatry
    • Harrison, P.J.1    Weinberger, D.R.2
  • 53
  • 54
  • 55
    • 0035287432 scopus 로고    scopus 로고
    • GLIA: Listening and talking to the synapse
    • Haydon PG (2001) GLIA: listening and talking to the synapse. Nat Rev Neurosci 2:185-193.
    • (2001) Nat Rev Neurosci , vol.2 , pp. 185-193
    • Haydon, P.G.1
  • 57
    • 2942537881 scopus 로고    scopus 로고
    • NMDA receptor hypofunction produces concomitant firing rate potentiation and burst activity reduction in the prefrontal cortex
    • Jackson ME, Homayoun H, Moghaddam B (2004) NMDA receptor hypofunction produces concomitant firing rate potentiation and burst activity reduction in the prefrontal cortex. Proc Natl Acad Sci U S A 101:8467-8472.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 8467-8472
    • Jackson, M.E.1    Homayoun, H.2    Moghaddam, B.3
  • 58
    • 0025952455 scopus 로고
    • Recent advances in the phenciclidine model of schizophrenia
    • Javitt DC, Zukin SR (1991) Recent advances in the phenciclidine model of schizophrenia. Am J Psychiat 148:1301-1308.
    • (1991) Am J Psychiat , vol.148 , pp. 1301-1308
    • Javitt, D.C.1    Zukin, S.R.2
  • 59
    • 1642458155 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor modulates fast synaptic inhibition by regulating GABA (A) receptor phosphorylation, activity, and cell-surface stability
    • Jovanovic JN, Thomas P, Kittler JT, Smart TG, Moss SJ (2004) Brain-derived neurotrophic factor modulates fast synaptic inhibition by regulating GABA (A) receptor phosphorylation, activity, and cell-surface stability. J Neurosci 24:522-530.
    • (2004) J Neurosci , vol.24 , pp. 522-530
    • Jovanovic, J.N.1    Thomas, P.2    Kittler, J.T.3    Smart, T.G.4    Moss, S.J.5
  • 60
    • 0035094264 scopus 로고    scopus 로고
    • Does fast dissociation from the dopamine D2 receptor explain the action of atypical antipsychotics?: A new hypothesis
    • Kapur S, Seeman P (2001) Does fast dissociation from the dopamine D2 receptor explain the action of atypical antipsychotics?: A new hypothesis. Am J Psychiatry 158:360-369.
    • (2001) Am J Psychiatry , vol.158 , pp. 360-369
    • Kapur, S.1    Seeman, P.2
  • 62
    • 19944397113 scopus 로고    scopus 로고
    • Ultrastructural alterations in hippocampal mossy fiber synapses in schizophrenia: A postmortem morphometric study
    • Kolomeets NS, Orlovskaya DD, Rachmanova VI, Uranova NA (2005) Ultrastructural alterations in hippocampal mossy fiber synapses in schizophrenia: A postmortem morphometric study. Synapse 57:47-55.
    • (2005) Synapse , vol.57 , pp. 47-55
    • Kolomeets, N.S.1    Orlovskaya, D.D.2    Rachmanova, V.I.3    Uranova, N.A.4
  • 63
    • 0021746255 scopus 로고
    • A neurohistological correlate of schizophrenia
    • Kovelman JA, Scheibel AB (1984) A neurohistological correlate of schizophrenia. Biol Psychiat 19:1601-1917.
    • (1984) Biol Psychiat , vol.19 , pp. 1601-1917
    • Kovelman, J.A.1    Scheibel, A.B.2
  • 64
    • 0030000465 scopus 로고    scopus 로고
    • Multiple structural elements determine subunit specificity of Mg2+ block in NMDA receptor channels
    • Kuner T, Schoepfer R (1996) Multiple structural elements determine subunit specificity of Mg2+ block in NMDA receptor channels. J Neurosci 16:3549-3558.
    • (1996) J Neurosci , vol.16 , pp. 3549-3558
    • Kuner, T.1    Schoepfer, R.2
  • 66
    • 0034054794 scopus 로고    scopus 로고
    • The role of endogenous sensitization in the pathophysiology of schizophrenia: Implications from recent brain imaging studies
    • Laruelle M (2000) The role of endogenous sensitization in the pathophysiology of schizophrenia: implications from recent brain imaging studies. Brain Res Rev 31:371-384.
    • (2000) Brain Res Rev , vol.31 , pp. 371-384
    • Laruelle, M.1
  • 67
    • 2342508828 scopus 로고    scopus 로고
    • Reduced spinophilin but not microtubule-associated protein 2 expression in the hippocampal formation in schizophrenia and mood disorders: Molecular evidence for a pathology of dendritic spines
    • Law AJ, Weickert CS, Hyde TM, Kleinman JE, Harrison PJ (2004a) Reduced spinophilin but not microtubule-associated protein 2 expression in the hippocampal formation in schizophrenia and mood disorders: molecular evidence for a pathology of dendritic spines. Am J Psychiatry 161:1848-1855.
    • (2004) Am J Psychiatry , vol.161 , pp. 1848-1855
    • Law, A.J.1    Weickert, C.S.2    Hyde, T.M.3    Kleinman, J.E.4    Harrison, P.J.5
  • 69
    • 0036279264 scopus 로고    scopus 로고
    • Disruption of prepulse inhibition of startle reflex in a neurodevelopmental model of schizophrenia: Reversal by clozapine, olanzapine and risperidone but not by haloperidol
    • Le Pen G, Moreau JL (2002) Disruption of prepulse inhibition of startle reflex in a neurodevelopmental model of schizophrenia: reversal by clozapine, olanzapine and risperidone but not by haloperidol. Neuropsychopharmacology 27:1-11.
    • (2002) Neuropsychopharmacology , vol.27 , pp. 1-11
    • Le Pen, G.1    Moreau, J.L.2
  • 70
    • 0033693190 scopus 로고    scopus 로고
    • Ventral tegmental area afferents to the prefrontal cortex maintain membrane potential 'up' states in pyramidal neurons via D1 dopamine receptors
    • Lewis BL, O'Donnell P (2000) Ventral tegmental area afferents to the prefrontal cortex maintain membrane potential 'up' states in pyramidal neurons via D1 dopamine receptors. Cerebral Cortex 10:1168-1175.
    • (2000) Cerebral Cortex , vol.10 , pp. 1168-1175
    • Lewis, B.L.1    O'Donnell, P.2
  • 71
    • 3142726152 scopus 로고    scopus 로고
    • Selective alterations in prefrontal cortical GABA neurotransmission in schizophrenia: A novel target for the treatment of working memory dysfunction
    • Lewis DA, Volk DW, Hashimoto T (2004) Selective alterations in prefrontal cortical GABA neurotransmission in schizophrenia: a novel target for the treatment of working memory dysfunction. Psychopharmacology (Berl) 174:143-150.
    • (2004) Psychopharmacology (Berl) , vol.174 , pp. 143-150
    • Lewis, D.A.1    Volk, D.W.2    Hashimoto, T.3
  • 72
  • 73
    • 0032814333 scopus 로고    scopus 로고
    • Altered GABA neurotransmission and prefrontal cortical dysfunction in schizophrenia
    • Lewis DA, Pierri JN, Volk DW, Melchitzky DS, Woo T-UW (1999) Altered GABA neurotransmission and prefrontal cortical dysfunction in schizophrenia. Biol Psychiat 46:616-626.
    • (1999) Biol Psychiat , vol.46 , pp. 616-626
    • Lewis, D.A.1    Pierri, J.N.2    Volk, D.W.3    Melchitzky, D.S.4    Woo, W.T.-U.5
  • 74
    • 0031783852 scopus 로고    scopus 로고
    • Excitotoxic lesions of the rat medial prefrontal cortex. Effects on abnormal behaviors associated with neonatal hippocampal damage
    • Lipska B, al-Amin H, Weinberger D (1998) Excitotoxic lesions of the rat medial prefrontal cortex. Effects on abnormal behaviors associated with neonatal hippocampal damage. Neuropsychopharmacology 19:451-464.
    • (1998) Neuropsychopharmacology , vol.19 , pp. 451-464
    • Lipska, B.1    Al-Amin, H.2    Weinberger, D.3
  • 75
    • 0028353106 scopus 로고
    • Subchronic treatment with haloperidol and clozapine in rats with neonatal excitotoxic hippocampal damage
    • Lipska BK, Weinberger DR (1994) Subchronic treatment with haloperidol and clozapine in rats with neonatal excitotoxic hippocampal damage. Neuropsychopharmacology 10:199-205.
    • (1994) Neuropsychopharmacology , vol.10 , pp. 199-205
    • Lipska, B.K.1    Weinberger, D.R.2
  • 76
    • 0027297279 scopus 로고
    • Postpuberal emergence of hyperresponsiveness to stress and to amphetamine after neonatal excitotoxic hippocanpal damage: A potential animal model of schizophrenia
    • Lipska BK, Jaskiw GE, Weinberger DR (1993) Postpuberal emergence of hyperresponsiveness to stress and to amphetamine after neonatal excitotoxic hippocanpal damage: a potential animal model of schizophrenia. Neuropsychopharmacology 90:67-75.
    • (1993) Neuropsychopharmacology , vol.90 , pp. 67-75
    • Lipska, B.K.1    Jaskiw, G.E.2    Weinberger, D.R.3
  • 78
    • 0041733102 scopus 로고    scopus 로고
    • Gene expression in dopamine and GABA systems in an animal model of schizophrenia: Effects of antipsychotic drugs
    • Lipska BK, Lerman DN, Khaing ZZ, Weickert CS, Weinberger DR (2003) Gene expression in dopamine and GABA systems in an animal model of schizophrenia: effects of antipsychotic drugs. Eur J Neurosci 18:391-402.
    • (2003) Eur J Neurosci , vol.18 , pp. 391-402
    • Lipska, B.K.1    Lerman, D.N.2    Khaing, Z.Z.3    Weickert, C.S.4    Weinberger, D.R.5
  • 79
    • 0005500246 scopus 로고
    • Neonatal excitotoxic hippocampal damage in rats cause post-pubertal changes in prepulse inhibition of startle and its disruption by apomorphine
    • Lipska BK, Swerdlow NR, Geyer MA, Jaskiw GE, Braff DL, Weinberger DR (1995) Neonatal excitotoxic hippocampal damage in rats cause post-pubertal changes in prepulse inhibition of startle and its disruption by apomorphine. Psychopharmacol 132:303-310.
    • (1995) Psychopharmacol , vol.132 , pp. 303-310
    • Lipska, B.K.1    Swerdlow, N.R.2    Geyer, M.A.3    Jaskiw, G.E.4    Braff, D.L.5    Weinberger, D.R.6
  • 81
    • 24144489818 scopus 로고    scopus 로고
    • Identification of singlenucleotide polymorphisms in the human N-methyl-D-aspartate receptor subunit NR2D gene, GRIN2D, and association study with schizophrenia
    • Makino C, Shibata H, Ninomiya H, Tashiro N, Fukumaki Y (2005) Identification of singlenucleotide polymorphisms in the human N-methyl-D-aspartate receptor subunit NR2D gene, GRIN2D, and association study with schizophrenia. Psychiatr Genet 15:215-221.
    • (2005) Psychiatr Genet , vol.15 , pp. 215-221
    • Makino, C.1    Shibata, H.2    Ninomiya, H.3    Tashiro, N.4    Fukumaki, Y.5
  • 82
    • 0037393438 scopus 로고    scopus 로고
    • Prefrontal cortex dysfunction during working memory performance in schizophrenia: Reconciling discrepant findings
    • Manoach DS (2003) Prefrontal cortex dysfunction during working memory performance in schizophrenia: reconciling discrepant findings. Schizophr Res 60:285-298.
    • (2003) Schizophr Res , vol.60 , pp. 285-298
    • Manoach, D.S.1
  • 83
    • 0034094628 scopus 로고    scopus 로고
    • Glutamate receptor expression in schizophrenic brain
    • Meador-Woodruff JH, Healy DJ (2000) Glutamate receptor expression in schizophrenic brain. Brain Res Rev 31:288-294.
    • (2000) Brain Res Rev , vol.31 , pp. 288-294
    • Meador-Woodruff, J.H.1    Healy, D.J.2
  • 85
    • 0035426751 scopus 로고    scopus 로고
    • Analysis of complex brain disorders with gene expression microarrays: Schizophrenia as a disease of the synapse
    • Mirnics K, Middleton FA, Lewis DA, Levitt P (2001) Analysis of complex brain disorders with gene expression microarrays: schizophrenia as a disease of the synapse. Trends Neurosci 24:479-486.
    • (2001) Trends Neurosci , vol.24 , pp. 479-486
    • Mirnics, K.1    Middleton, F.A.2    Lewis, D.A.3    Levitt, P.4
  • 86
    • 10644223699 scopus 로고    scopus 로고
    • Neonatal lesions of the ventral hippocampal formation alter GABA-A receptor subunit mRNA expression in adult rat frontal pole
    • Mitchell CP, Grayson DR, Goldman MB (2005) Neonatal lesions of the ventral hippocampal formation alter GABA-A receptor subunit mRNA expression in adult rat frontal pole. Biol Psychiatry 57:49-55.
    • (2005) Biol Psychiatry , vol.57 , pp. 49-55
    • Mitchell, C.P.1    Grayson, D.R.2    Goldman, M.B.3
  • 87
    • 0030900732 scopus 로고    scopus 로고
    • Activation of glutamatergic neurotransmission by ketamine: A novel step in the pathway from NMDA receptor blockade to dopaminergic and cognitive disruptions associated with the prefrontal cortex
    • Moghaddam B, Adams B, Verma A, Daly D (1997) Activation of glutamatergic neurotransmission by ketamine: a novel step in the pathway from NMDA receptor blockade to dopaminergic and cognitive disruptions associated with the prefrontal cortex. J Neurosci 17:2921-2927.
    • (1997) J Neurosci , vol.17 , pp. 2921-2927
    • Moghaddam, B.1    Adams, B.2    Verma, A.3    Daly, D.4
  • 89
    • 0028343648 scopus 로고
    • Developmental and regional expression in the rat brain and functional properties of four NMDA receptors
    • Monyer H, Burnashev N, Laurie DJ, Sakmann B, Seeburg PH (1994) Developmental and regional expression in the rat brain and functional properties of four NMDA receptors. Neuron 12:529-540.
    • (1994) Neuron , vol.12 , pp. 529-540
    • Monyer, H.1    Burnashev, N.2    Laurie, D.J.3    Sakmann, B.4    Seeburg, P.H.5
  • 90
    • 0036716777 scopus 로고    scopus 로고
    • Neonatal hippocampal damage alters electrophysiological properties of prefrontal cortical neurons in adult rats
    • O'Donnell P, Lewis BL, Weinberger DR, Lipska BK (2002) Neonatal hippocampal damage alters electrophysiological properties of prefrontal cortical neurons in adult rats. Cereb Cortex 12:975-982.
    • (2002) Cereb Cortex , vol.12 , pp. 975-982
    • O'Donnell, P.1    Lewis, B.L.2    Weinberger, D.R.3    Lipska, B.K.4
  • 91
    • 2342529024 scopus 로고    scopus 로고
    • Neuregulin1 downregulates postsynaptic GABAA receptors at the hippocampal inhibitory synapse
    • Okada M, Corfas G (2004) Neuregulin1 downregulates postsynaptic GABAA receptors at the hippocampal inhibitory synapse. Hippocampus 14:337-344.
    • (2004) Hippocampus , vol.14 , pp. 337-344
    • Okada, M.1    Corfas, G.2
  • 92
    • 0028850552 scopus 로고
    • Glutamate receptor dysfunction and schizophrenia
    • Olney JW, Farber NB (1995) Glutamate receptor dysfunction and schizophrenia. Arch Gen Psychiat 52:998-1007.
    • (1995) Arch Gen Psychiat , vol.52 , pp. 998-1007
    • Olney, J.W.1    Farber, N.B.2
  • 94
    • 0031878186 scopus 로고    scopus 로고
    • Isolation rearing affects sequential organization of motor behavior in post-pubertal but not pre-pubertal Lister and Sprague-Dawley rats
    • Paulus MP, Bakshi V, Geyer MA (1998) Isolation rearing affects sequential organization of motor behavior in post-pubertal but not pre-pubertal Lister and Sprague-Dawley rats. Behav Brain Res 94:271-280.
    • (1998) Behav Brain Res , vol.94 , pp. 271-280
    • Paulus, M.P.1    Bakshi, V.2    Geyer, M.A.3
  • 96
    • 0031927030 scopus 로고    scopus 로고
    • Frontotemporal cerebral blood flow change during executive and declarative memory tasks in schizophrenia: A positron emission tomography study
    • Ragland JD, Gur RC, Glahn DC, Censits DM, Smith RJ, Lazarev MG, Alavi A, Gur RE (1998) Frontotemporal cerebral blood flow change during executive and declarative memory tasks in schizophrenia: a positron emission tomography study. Neuropsychology 12:399-413.
    • (1998) Neuropsychology , vol.12 , pp. 399-413
    • Ragland, J.D.1    Gur, R.C.2    Glahn, D.C.3    Censits, D.M.4    Smith, R.J.5    Lazarev, M.G.6    Alavi, A.7    Gur, R.E.8
  • 97
    • 6344270074 scopus 로고    scopus 로고
    • An animal model of chronic placental insufficiency: Relevance to neurodevelopmental disorders including schizophrenia
    • Rehn AE, Van Den Buuse M, Copolov D, Briscoe T, Lambert G, Rees S (2004) An animal model of chronic placental insufficiency: relevance to neurodevelopmental disorders including schizophrenia. Neuroscience 129:381-391.
    • (2004) Neuroscience , vol.129 , pp. 381-391
    • Rehn, A.E.1    Van Den Buuse, M.2    Copolov, D.3    Briscoe, T.4    Lambert, G.5    Rees, S.6
  • 98
    • 0029155544 scopus 로고
    • Postnatal maturation of the dopaminergic innervation of monkey prefrontal and motor cortices: A tyrosine hydroxylase immunohistochemical analysis
    • Rosenberg DR, Lewis DA (1995) Postnatal maturation of the dopaminergic innervation of monkey prefrontal and motor cortices: a tyrosine hydroxylase immunohistochemical analysis. J Comp Neurol 358:383-400.
    • (1995) J Comp Neurol , vol.358 , pp. 383-400
    • Rosenberg, D.R.1    Lewis, D.A.2
  • 99
    • 0030839774 scopus 로고    scopus 로고
    • Neonatal lesions of the rat ventral hippocampus result in hyperlocomotion and deficits in social behavior in adulthood
    • Sams-Dodd F, Lipska BK, Weinberger DR (1997) Neonatal lesions of the rat ventral hippocampus result in hyperlocomotion and deficits in social behavior in adulthood. Psychopharmacol 132:303-310.
    • (1997) Psychopharmacol , vol.132 , pp. 303-310
    • Sams-Dodd, F.1    Lipska, B.K.2    Weinberger, D.R.3
  • 101
    • 0023254675 scopus 로고
    • Dopamine receptors and the dopamine hypothesis of schizophrenia
    • Seeman P (1987) Dopamine receptors and the dopamine hypothesis of schizophrenia. Synapse 1:133-152.
    • (1987) Synapse , vol.1 , pp. 133-152
    • Seeman, P.1
  • 103
    • 0015536067 scopus 로고
    • Amphetamine psychosis: A model of schizophrenia mediated by catecholamines
    • Snyder SH (1973) Amphetamine psychosis: a model of schizophrenia mediated by catecholamines. Am J Psychiat 130:61-67.
    • (1973) Am J Psychiat , vol.130 , pp. 61-67
    • Snyder, S.H.1
  • 104
    • 0030298003 scopus 로고    scopus 로고
    • Expression of NMDAR2D glutamate receptor subunit mRNA in neurochemically identified interneurons in the rat neostriatum, neocortex and hippocampus
    • Standaert DG, Landwehrmeyer GB, Kerner JA, Penney JB, Jr., Young AB (1996) Expression of NMDAR2D glutamate receptor subunit mRNA in neurochemically identified interneurons in the rat neostriatum, neocortex and hippocampus. Mol Brain Res 42:89-102.
    • (1996) Mol Brain Res , vol.42 , pp. 89-102
    • Standaert, D.G.1    Landwehrmeyer, G.B.2    Kerner, J.A.3    Penney, J.B.4    Young, A.B.5
  • 105
    • 0026607626 scopus 로고
    • Abnormal reinnervation as a basis for schizophrenia: A hypothesis
    • Stevens JR (1992) Abnormal reinnervation as a basis for schizophrenia: a hypothesis. Arch Gen Psychiat 49:238-243.
    • (1992) Arch Gen Psychiat , vol.49 , pp. 238-243
    • Stevens, J.R.1
  • 106
    • 0028810381 scopus 로고
    • Increased sensitivity to the sensorimotor gating-disruptive effecs of apomorphine after lesions of medial prefrontal cortex of ventral hippocampus in adult rats
    • Swerdlow NR, Lipska BK, Weinberger DR, Braff DL, Jaskiw GE, Geyer MA (1995) Increased sensitivity to the sensorimotor gating-disruptive effecs of apomorphine after lesions of medial prefrontal cortex of ventral hippocampus in adult rats. Psychopharmacology 122:27-34.
    • (1995) Psychopharmacology , vol.122 , pp. 27-34
    • Swerdlow, N.R.1    Lipska, B.K.2    Weinberger, D.R.3    Braff, D.L.4    Jaskiw, G.E.5    Geyer, M.A.6
  • 107
    • 16344365442 scopus 로고    scopus 로고
    • Developmental pathology, dopamine, and stress: A model for the age of onset of schizophrenia symptoms
    • Thompson JL, Pogue-Geile MF, Grace AA (2004) Developmental pathology, dopamine, and stress: a model for the age of onset of schizophrenia symptoms. Schizophr Bull 30:875-900.
    • (2004) Schizophr Bull , vol.30 , pp. 875-900
    • Thompson, J.L.1    Pogue-Geile, M.F.2    Grace, A.A.3
  • 108
    • 2642566270 scopus 로고    scopus 로고
    • Dopamine-glutamate interactions controlling prefrontal cortical pyramidal cell excitability involve multiple signaling mechanisms
    • Tseng KY, O'Donnell P (2004) Dopamine-glutamate interactions controlling prefrontal cortical pyramidal cell excitability involve multiple signaling mechanisms. J Neurosci 24:5131-5139.
    • (2004) J Neurosci , vol.24 , pp. 5131-5139
    • Tseng, K.Y.1    O'Donnell, P.2
  • 109
    • 84919843042 scopus 로고    scopus 로고
    • Peri-adolescent maturation of dopamine modulation of interneuron activity in normal animals and in a developmental animal model of schizophrenia
    • Tseng KY, O'Donnell P (2006) Peri-adolescent maturation of dopamine modulation of interneuron activity in normal animals and in a developmental animal model of schizophrenia. Biol Psychiat 59:196S.
    • (2006) Biol Psychiat , vol.59 , pp. 196S
    • Tseng, K.Y.1    O'Donnell, P.2
  • 110
    • 34247159396 scopus 로고    scopus 로고
    • Dopamine modulation of prefrontal cortical interneurons changes during adolescence
    • Tseng JY, O'Donnell P (2007) Dopamine modulation of prefrontal cortical interneurons changes during adolescence. Cereb Cortex 17:1235-1240.
    • (2007) Cereb Cortex , vol.17 , pp. 1235-1240
    • Tseng, J.Y.1    O'Donnell, P.2
  • 111
    • 0026346136 scopus 로고
    • The biochemical basis of relapse and drug response in schizophrenia: Review and hypothesis
    • van Kammen DP (1991) The biochemical basis of relapse and drug response in schizophrenia: review and hypothesis. Psychological Medicine 21:881-895.
    • (1991) Psychological Medicine , vol.21 , pp. 881-895
    • Van Kammen, D.P.1
  • 113
    • 0036955770 scopus 로고    scopus 로고
    • Impaired prefrontal inhibition in schizophrenia: Relevance for cognitive dysfunction
    • Volk DW, Lewis DA (2002) Impaired prefrontal inhibition in schizophrenia: relevance for cognitive dysfunction. Physiol Behav 77:501-505.
    • (2002) Physiol Behav , vol.77 , pp. 501-505
    • Volk, D.W.1    Lewis, D.A.2
  • 114
    • 0036784474 scopus 로고    scopus 로고
    • Reciprocal alterations in pre- and postsynaptic inhibitory markers at chandelier cell inputs to pyramidal neurons in schizophrenia
    • Volk DW, Pierri JN, Fritschy JM, Auh S, Sampson AR, Lewis DA (2002) Reciprocal alterations in pre- and postsynaptic inhibitory markers at chandelier cell inputs to pyramidal neurons in schizophrenia. Cereb Cortex 12:1063-1070.
    • (2002) Cereb Cortex , vol.12 , pp. 1063-1070
    • Volk, D.W.1    Pierri, J.N.2    Fritschy, J.M.3    Auh, S.4    Sampson, A.R.5    Lewis, D.A.6
  • 115
    • 0030939945 scopus 로고    scopus 로고
    • Metbolic hyperfrontality and psychopathology in the ketamine model of psychosis using emission tomography (PET) and [18F]fluorodeoxyglucose (FDG)
    • Vollenweider FX, Leenders KL, Scharfetter C, Antonini A, Maguire P, Missimer J, Angst J (1997) Metbolic hyperfrontality and psychopathology in the ketamine model of psychosis using emission tomography (PET) and [18F]fluorodeoxyglucose (FDG). Eur Neuropsychopharmacol 7:9-24.
    • (1997) Eur Neuropsychopharmacol , vol.7 , pp. 9-24
    • Vollenweider, F.X.1    Leenders, K.L.2    Scharfetter, C.3    Antonini, A.4    Maguire, P.5    Missimer, J.6    Angst, J.7
  • 118
    • 0030022433 scopus 로고    scopus 로고
    • Developmental and regional expression of NMDA receptor subtypes containing the NR2D subunit in rat brain
    • Wenzel A, Villa M, Mohler H, Benke D (1996) Developmental and regional expression of NMDA receptor subtypes containing the NR2D subunit in rat brain. J Neurochem 66:1240-1248.
    • (1996) J Neurochem , vol.66 , pp. 1240-1248
    • Wenzel, A.1    Villa, M.2    Mohler, H.3    Benke, D.4
  • 119
    • 0028821024 scopus 로고
    • Pharmacological properties of recombinant N-methyl-D-aspartate (NMDA) receptors containing the epsilon 4 (NR2D) subunit
    • Williams K (1995) Pharmacological properties of recombinant N-methyl-D-aspartate (NMDA) receptors containing the epsilon 4 (NR2D) subunit. Neurosci Lett 184:181-184.
    • (1995) Neurosci Lett , vol.184 , pp. 181-184
    • Williams, K.1
  • 120
    • 0030832501 scopus 로고    scopus 로고
    • Peripubertal refinement of the intrinsic and associational circuitry in monkey prefrontal cortex
    • Woo TU, Pucak ML, Kye CH, Matus CV, Lewis DA (1997) Peripubertal refinement of the intrinsic and associational circuitry in monkey prefrontal cortex. Neuroscience 80:1149-1158.
    • (1997) Neuroscience , vol.80 , pp. 1149-1158
    • Woo, T.U.1    Pucak, M.L.2    Kye, C.H.3    Matus, C.V.4    Lewis, D.A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.