Association of circulating endothelial microparticles with cardiometabolic risk factors in the Framingham Heart Study

European Heart Journal

Volumn 35, Issue 42, 2014, Pages 2972-2979

  Amabile, Nicolas ^a,b   Cheng, Susan ^c,d   Renard, Jean Marie ^a,b   Larson, Martin G ^c,e   Ghorbani, Anahita ^f   McCabe, Elizabeth ^e,f   Griffin, Gabriel ^g   Guerin, Coralie ^a,b   Ho, Jennifer E ^c,f   Shaw, Stanley Y ^f   Cohen, Kenneth S ^h   Vasan, Ramachandran S ^c,i   Tedgui, Alain ^a,b   Boulanger, Chantal M ^a,b   Wang, Thomas J ^c,f,j  

^a PARIS CARDIOVASCULAR RESEARCH CENTER   (France)

^b UNIVERSITÉ PARIS DESCARTES   (France)

^c FRAMINGHAM HEART STUDY   (United States)

^d BRIGHAM AND WOMEN S HOSPITAL   (United States)

^e Boston University   (United States)

^f MASSACHUSETTS GENERAL HOSPITAL   (United States)

^g DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^h UNIVERSITY OF CHICAGO MEDICAL CENTER   (United States)

ⁱ BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^j VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

more..

Author keywords

Cardiovascular risk factors; Endothelium; Microparticles

Indexed keywords

CD31 ANTIGEN; FIBRINOGEN RECEPTOR; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL; VASCULAR ENDOTHELIAL CADHERIN; LEUKOCYTE ANTIGEN;

AGED; ARTICLE; BODY MASS; CARDIOMETABOLIC RISK; CARDIOVASCULAR RISK; CHOLESTEROL BLOOD LEVEL; COMMUNITY ASSESSMENT; DIABETES MELLITUS; ENDOTHELIAL MICROPARTICLE; FEMALE; FLOW CYTOMETRY; FRAMINGHAM RISK SCORE; HUMAN; HYPERTENSION; HYPERTRIGLYCERIDEMIA; MAJOR CLINICAL STUDY; MALE; METABOLIC SYNDROME X; PHENOTYPE; SEX DIFFERENCE; SMOKING; TRIACYLGLYCEROL BLOOD LEVEL; WAIST CIRCUMFERENCE; CARDIOVASCULAR DISEASE; ENDOTHELIUM CELL; LONGITUDINAL STUDY; MEMBRANE MICROPARTICLE; METABOLISM; PATHOLOGY; RISK FACTOR; VASCULAR ENDOTHELIUM;

AGED; ANTIGENS, CD; CARDIOVASCULAR DISEASES; CELL-DERIVED MICROPARTICLES; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; FEMALE; HUMANS; LONGITUDINAL STUDIES; MALE; METABOLIC SYNDROME X; RISK FACTORS;

EID: 84905639796     PISSN: 0195668X     EISSN: 15229645     Source Type: Journal    
DOI: 10.1093/eurheartj/ehu153     Document Type: Article

References (45)

1. Dignat-George F, Boulanger CM. Themany facesofendothelial microparticles. Arter-ioscler Thromb Vasc Biol 2011;31:27-33.
2. Amabile N, Rautou PE, Tedgui A, Boulanger CM. Microparticles: key protagonists in cardiovascular disorders. Semin Thromb Hemost 2010;36:907-916.
3. Ferreira AC, Peter AA, Mendez AJ, Jimenez JJ, Mauro LM, Chirinos JA, Ghany R, Virani S, Garcia S, Horstman LL, Purow J, Jy W, Ahn YS, de Marchena E. Postprandial hypertriglyceridemia increases circulating levels of endothelial cell microparticles. Circulation 2004;110:3599-3603.
4. Sabatier F, Darmon P, Hugel B, Combes V, Sanmarco M, Velut JG, Arnoux D, Charpiot P, Freyssinet JM, Oliver C, Sampol J, Dignat-George F. Type 1 and type 2 diabetic patients display different patterns of cellular microparticles. Diabetes 2002;51:2840-2845.
5. Preston RA, Jy W, Jimenez JJ, Mauro LM, Horstman LL, Valle M, Aime G, Ahn YS. Effects of severe hypertension on endothelial and platelet microparticles. Hypertension 2003;41:211-217.
6. Pirro M, Schillaci G, Paltriccia R, Bagaglia F, Menecali C, Mannarino MR, Capanni M, Velardi A, Mannarino E. Increased ratio of CD31+/CD42-microparticles to endo-thelial progenitors as a novel marker of atherosclerosis in hypercholesterolemia. Arterioscler Thromb Vasc Biol 2006;26:2530-2535.
7. Amabile N, Boulanger CM. Circulating microparticle levelsinpatients with coronary artery disease: a new indicator of vulnerability? Eur Heart J 2011;32:1958-1960.
8. Dawber TR, Meadors GF, Moore FE Jr. Epidemiological approachesto heart disease: the Framingham Study. Am J Public Health Nation's Health 1951;41:279-281.
9. Kannel WB, Feinleib M, McNamara PM, Garrison RJ, Castelli WP. An investigation of coronary heart disease in families. The Framingham offspring study. Am J Epidemiol 1979;110:281-290.
10. Wilson PW, Paffenbarger RS Jr, Morris JN, Havlik RJ. Assessment methods for physical activity and physical fitness in population studies: report of a NHLBI workshop. Am Heart J 1986;111:1177-1192.
11. Grundy SM, Cleeman JI, Daniels SR, Donato KA, Eckel RH, Franklin BA, Gordon DJ, Krauss RM, Savage PJ, Smith SC, Spertus JA, Costa F. Diagnosis and management of the metabolic syndrome. Circulation 2005;112:2735-2752.
12. Arsenault BJ, Lemieux I, Despres JP, Wareham NJ, Kastelein JJ, Khaw KT, Boekholdt SM. The hypertriglyceridemic-waist phenotype and the risk of coronary artery disease: results from the EPIC-Norfolk prospective population study. CMAJ 2010;182:1427-1432.
13. D'Agostino RB Sr, Vasan RS, Pencina MJ, Wolf PA, Cobain M, Massaro JM, Kannel WB. General cardiovascular risk profile for use in primary care: the Framing-ham Heart Study. Circulation 2008;117:743-753.
14. Amabile N, Guerin AP, Leroyer A, Mallat Z, Nguyen C, Boddaert J, London GM, Tedgui A, Boulanger CM. Circulating endothelial microparticles are associated with vascular dysfunction in patients with end-stage renal failure. J Am Soc Nephrol 2005;16:3381-3388.
15. Laird NM, Ware JH. Random-effects models for longitudinal data. Biometrics 1982; 38:963-974.
16. Tushuizen ME, Nieuwland R, Rustemeijer C, Hensgens BE, Sturk A, Heine RJ, Diamant M. Elevated endothelial microparticles following consecutive meals are associated with vascular endothelial dysfunction in type 2 diabetes. Diabetes Care 2007;30:728-730.
17. Lundman P, Eriksson MJ, Silveira A, Hansson L-O, Pernow J, Ericsson C-Gr, Hamsten A, Tornvall P. Relation of hypertriglyceridemia to plasma concentrations of biochemical markers of inflammation and endothelial activation (C-reactive protein, interleukin-6, soluble adhesion molecules, von Willebrand factor, and endothelin-1). Am J Cardiol 2003;91:1128-1131.
18. Miller M, Stone NJ, Ballantyne C, Bittner V, Criqui MH, Ginsberg HN, Goldberg AC, Howard WJ, Jacobson MS, Kris-Etherton PM, Lennie TA, Levi M, Mazzone T, Pennathur S. Triglycerides and cardiovascular disease. Circulation 2011;123: 2292-2333.
19. Nappo F, Esposito K, Cioffi M, Giugliano G, Molinari AM, Paolisso G, Marfella R, Giugliano D. Postprandial endothelial activation in healthy subjects andin type 2 diabetic patients: role of fat and carbohydrate meals. J Am Coll Cardiol 2002;39: 1145-1150.
20. Castelli WP. The triglyceride issue: a view from Framingham. Am Heart J 1986;112: 432-437.
21. Mazza A, Tikhonoff V, Schiavon L, Casiglia E. Triglycerides + high-density-lipoprotein-cholesterol dyslipidaemia, a coronary risk factor in elderly women: the CArdiovascular STudy in the ELderly. Intern Med J 2005;35:604-610.
22. Tirosh A, Rudich A, Shochat T, Tekes-Manova D, Israeli E, Henkin Y, Kochba I, Shai I. Changes in triglyceride levels and risk for coronary heart disease in young men. Ann Intern Med 2007;147:377-385.
23. Nomura S, Shouzu A, Omoto S, Nishikawa M, Iwasaka T, Fukuhara S. Activated platelet and oxidized LDL induce endothelial membrane vesiculation: clinical significance of endothelial cell-derived microparticles in patients with type 2 diabetes. Clin Appl Thromb Hemost 2004;10:205-215.
24. Tramontano AF, O'Leary J, Black AD, Muniyappa R, Cutaia MV, El-Sherif N. Statin decreases endothelial microparticle release from human coronary artery endothe-lial cells: implication for the Rho-kinase pathway. Biochem Biophys Res Commun 2004; 320:34-38.
25. Mobarrez F, Egberg N, Antovic J, Brpijersen A, Jörneskog G, Wallén H. Release of endothelial microparticles in vivo during atorvastatin treatment; a randomized double-blind placebo-controlled study. Thromb Res 2012;129:95-97.
26. Huang B, Cheng Y, Xie Q, Lin G, Wu Y, Feng Y, Gao J, Xu D. Effect of 40 mg versus 10 mg of atorvastatin on oxidized low-density lipoprotein, high-sensitivity C-reactive protein, circulating endothelial-derived microparticles, and endothelial progenitor cells in patients with ischemic cardiomyopathy. Clin Cardiol 2012;35: 125-130.
27. Gami AS, Witt BJ, Howard DE, Erwin PJ, Gami LA, Somers VK, Montori VM. Metabolic syndrome and risk of incident cardiovascular events and death: a systematic review and meta-analysis of longitudinal studies. J Am Coll Cardiol 2007;49:403-414.
28. Arteaga RB, Chirinos JA, Soriano AO, Jy W, Horstman L, Jimenez JJ, Mendez A, Ferreira A, de Marchena E, Ahn YS. Endothelial microparticles and platelet and leukocyte activation in patients with the metabolic syndrome. Am J Cardiol 2006; 98:70-74.
29. Esposito K, Ciotola M, Giugliano D. Pioglitazone reduces endothelial microparticles in the metabolic syndrome. Arterioscler Thromb Vasc Biol 2006;26:1926.
30. Agouni A, Lagrue-Lak-Hal AH, Ducluzeau PH, Mostefai HA, Draunet-Busson C, Leftheriotis G, Heymes C, Martinez MC, Andriantsitohaina R. Endothelial dysfunction caused by circulating microparticles from patients with metabolic syndrome. Am J Pathol 2008;173:1210-1219.
31. La Vignera S, Condorelli R, Vicari E, D'Agata R, Calogero AE. Circulating endothelial progenitor cells and endothelial microparticles in patients with arterial erectile dysfunction and metabolic syndrome. J Androl 2012;33:202-209.
32. Diamant M, Nieuwland R, Pablo RF, Sturk A, Smit JW, Radder JK. Elevated numbers of tissue-factor exposing microparticles correlate with components of the metabolic syndrome in uncomplicated type 2 diabetes mellitus. Circulation 2002;106:2442-2447.
33. Mattsson N, Rönnemaa T, Juonala M, Viikari JSA, Jokinen E, Hutri-Kähönen N, Kähönen M, Laitinen T, Raitakari OT. Arterial structure and function in young adults with the metabolic syndrome: the Cardiovascular Risk in Young Finns Study. Eur Heart J 2008;29:784-791.
34. Vykoukal D, Davies MG. Vascular biology of metabolic syndrome. J Vasc Surg 2011; 54:819-831.
35. Brodsky SV, Malinowski K, Golightly M, Jesty J, Goligorsky MS. Plasminogen activator inhibitor-1 promotes formation of endothelial microparticles with procoagulant potential. Circulation 2002;106:2372-2378.
36. Nomura S, Shouzu A, Omoto S, Nishikawa M, Iwasaka T. Effects of losartan and sim-vastatin on monocyte-derived microparticles in hypertensive patients with and without type 2 diabetes mellitus. Clin Appl Thromb Hemost 2004;10:133-141.
37. Nomura S, Shouzu A, Omoto S, Nishikawa M, Iwasaka T. Long-term treatment with nifedipine modulates procoagulant marker and C-C chemokine in hypertensive patients with type 2 diabetes mellitus. Thromb Res 2005;115:277-285.
38. van Ierssel SH, Van Craenenbroeck EM, Conraads VM, Van Tendeloo VF, Vrints CJ, Jorens PG, Hoymans VY. Flow cytometric detection of endothelial microparticles (EMP): Effects of centrifugation and storage alter with the phenotype studied. Thromb Res 2010;125:332-339.
39. Takahashi T, Kobayashi S, Fujino N, Suzuki T, Ota C, Tando Y, He M, Yamada M, Kurosawa S, Yamaya M, Kubo H. Differences in the released endothelial micropar-ticle subtypesbetween human pulmonary microvascular endothelial cells and aortic endothelial cells in vitro. Exp Lung Res 2013;39:155-161.
40. Koga H, Sugiyama S, Kugiyama K, Watanabe K, Fukushima H, Tanaka T, Sakamoto T, Yoshimura M, Jinnouchi H, Ogawa H. Elevated levels of VE-cadherin-positive endo-thelial microparticles in patients with type 2 diabetes mellitus and coronary artery disease. J Am Coll Cardiol 2005;45:1622-1630.
41. Tramontano AF, Lyubarova R, Tsiakos J, Palaia T, Deleon JR, Ragolia L. Circulating endothelial microparticles in diabetes mellitus. Mediators Inflamm 2010;2010: 250476.
42. Meigs JB, Cupples LA, Wilson PW. Parental transmission of type 2 diabetes: the Framingham Offspring Study. Diabetes 2000;49:2201-2207.
43. Heiss C, Amabile N, Lee AC, Real WM, Schick SF, Lao D, Wong ML, Jahn S, Angeli FS, Minasi P, Springer ML, Hammond SK, Glantz SA, Grossman W, Balmes JR, Yeghiazarians Y. Brief secondhand smoke exposure depresses endothelial progenitor cells activity and endothelial function: sustained vascular injury and blunted nitric oxide production. J Am Coll Cardiol 2008;51: 1760-1771.
44. Gordon C, Gudi K, Krause A, Sackrowitz R, Harvey BG, Strulovici-Barel Y, Mezey JG, Crystal RG. Circulating endothelial microparticles as a measure of early lung destruction in cigarette smokers. Am J Respir Crit Care Med 2011;184: 224-232.
45. Robert S, Lacroix R, Poncelet P, Harhouri K, Bouriche T, Judicone C, Wischhusen J, Arnaud L, Dignat-George F. High-sensitivity flow cytometryprovides accesstostan-dardized measurementofsmall-size microparticles-brief report. Arterioscler Thromb Vasc Biol 2012;32:1054-1058.