Postoperative complications reduce adjuvant chemotherapy use in resectable pancreatic cancer

Annals of Surgery

Volumn 260, Issue 2, 2014, Pages 372-377

  Merkow, Ryan P ^a,b,c   Bilimoria, Karl Y ^a,b   Tomlinson, James S ^d   Paruch, Jennifer L ^a,c   Fleming, Jason B ^e   Talamonti, Mark S ^c,f   Ko, Clifford Y ^a,d   Bentrem, David J ^b,g  

^a AMERICAN COLLEGE OF SURGEONS   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

^c UNIVERSITY OF CHICAGO   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^f NORTHSHORE UNIVERSITY HEALTHSYSTEM   (United States)

^g JESSE BROWN VA MEDICAL CENTER   (United States)

Author keywords

ACS NSQIP; Adjuvant therapy; Complications; NCDB; Pancreatic cancer; Surgery

Indexed keywords

ADULT; AGED; ASSISTED VENTILATION; CANCER ADJUVANT THERAPY; CANCER SURGERY; CEREBROVASCULAR ACCIDENT; COMA; CONFERENCE PAPER; DISEASE SEVERITY; FEMALE; FUNCTIONAL STATUS; HEART ARREST; HEART INFARCTION; HUMAN; KIDNEY FAILURE; MAJOR CLINICAL STUDY; MALE; MORBIDITY; PANCREAS ADENOCARCINOMA; PANCREAS CANCER; PANCREAS SURGERY; PANCREATICODUODENECTOMY; PNEUMONIA; POSTOPERATIVE COMPLICATION; PRIORITY JOURNAL; REPEAT PROCEDURE; RESPIRATORY FAILURE; RESPIRATORY TRACT INTUBATION; SEPSIS; SHOCK; SURGICAL INFECTION; THERAPY DELAY; UNDERWEIGHT; URINARY TRACT INFECTION; VENOUS THROMBOEMBOLISM; WOUND DEHISCENCE; WOUND INFECTION; ADENOCARCINOMA; ADJUVANT CHEMOTHERAPY; CANCER STAGING; CLINICAL TRIAL; MIDDLE AGED; MULTICENTER STUDY; PANCREATIC NEOPLASMS; PATHOLOGY; PATIENT SELECTION; POSTOPERATIVE COMPLICATIONS; UNITED STATES; UTILIZATION;

ADENOCARCINOMA; AGED; CHEMOTHERAPY, ADJUVANT; FEMALE; HUMANS; MALE; MIDDLE AGED; NEOPLASM STAGING; PANCREATIC NEOPLASMS; PATIENT SELECTION; POSTOPERATIVE COMPLICATIONS; UNITED STATES;

EID: 84905583169     PISSN: 00034932     EISSN: 15281140     Source Type: Journal    
DOI: 10.1097/SLA.0000000000000378     Document Type: Conference Paper

References (30)

1. Siegel R, Naishadham D, Jemal A. Cancer statistics, 2013. CA Cancer J Clin. 2013;63:11-30.
2. Department of Research and Scientific Affairs of the Pancreatic Cancer Action Network. The alarming rise of pancreatic cancer deaths in the United States: why we need to stem the tide today.. http://www.pancan.org/section research/reports/pdf/incidence report 2012.pdf. Accessed July 2, 2013.
3. Parikh P, Shiloach M, Cohen ME, et al. Pancreatectomy risk calculator: an ACS-NSQIP resource. HPB (Oxford). 2010;12:488-497.
4. Kneuertz PJ, Pitt HA, Bilimoria KY, et al. Risk of morbidity and mortality following hepato-pancreato-biliary surgery. J Gastrointest Surg. 2012;16:1727-1735.
5. Oettle H, Post S, Neuhaus P, et al. Adjuvant chemotherapy with gemcitabine vs observation in patients undergoing curative-intent resection of pancreatic cancer: a randomized controlled trial. JAMA. 2007;297:267-277.
6. Neoptolemos JP, Dunn JA, Stocken DD, et al. Adjuvant chemoradiotherapy and chemotherapy in resectable pancreatic cancer: a randomised controlled trial. Lancet. 2001;358:1576-1585.
7. Neoptolemos JP, Stocken DD, Friess H, et al. A randomized trial of chemoradiotherapy and chemotherapy after resection of pancreatic cancer. N Engl J Med. 2004;350:1200-1210.
8. Klinkenbijl JH, Jeekel J, Sahmoud T, et al. Adjuvant radiotherapy and 5-fluorouracil after curative resection of cancer of the pancreas and periampullary region: phase III trial of the EORTC gastrointestinal tract cancer cooperative group. Ann Surg. 1999;230:776-782; discussion 782-784.
9. National Comprehensive Cancer Network. Clinical practice guidelines in oncology: pancreatic adenocarcinoma. Version 1.2013. http://site.acsnsqip.org/. Accessed July 1, 2013.
10. Bilimoria KY, Bentrem DJ, Lillemoe KD, et al. Assessment of pancreatic cancer care in the United States based on formally developed quality indicators. J Natl Cancer Inst. 2009;101:848-859.
11. Vincent A, Herman J, Schulick R, et al. Pancreatic cancer. Lancet. 2011;378:607-620.
12. Evans DB: Preoperative chemoradiation for resectable and locally advanced adenocarcinoma of the pancreas. J Gastrointest Surg. 2001;5:2-5.
13. American College of Surgeons-National Surgical Quality Improvement Program. http://site.acsnsqip.org/. Accessed January 1, 2013.
14. American College of Surgeons-National Surgical Quality Improvement Program. Semiannual Report: January 2013. Chicago, IL: American College of Surgeons; 2013.
15. American College of Surgeons. Facility Oncology Registry Data Standards. Chicago, IL: Commission on Cancer (2003-2012). http://www.facs.org/cancer/ncdb/ cocmanuals.html. Accessed April 15, 2013.
16. Lawson EH, Ko CY, Louie R, et al. Linkage of a clinical surgical registry with Medicare inpatient claims data using indirect identifiers. Surgery. 2013;153:423-430.
17. Khuri SF, Daley J, Henderson W, et al. The Department of Veterans Affairs' NSQIP: the first national, validated, outcome-based, risk-adjusted, and peercontrolled program for the measurement and enhancement of the quality of surgical care. National VA Surgical Quality Improvement Program. Ann Surg. 1998;228:491-507.
18. Khuri SF, Henderson WG, Daley J, et al. Successful implementation of the Department of Veterans Affairs' National Surgical Quality Improvement Program in the private sector: the patient safety in surgery study. Ann Surg. 2008;248:329-336.
19. Khuri SF, Henderson WG, Daley J, et al. The patient safety in surgery study: background, study design, and patient populations. J Am Coll Surg. 2007;204:1089-1102.
20. Cohen ME, Ko CY, Bilimoria KY, et al. Optimizing ACS NSQIP modeling for evaluation of surgical quality and risk: patient risk adjustment, procedure mix adjustment, shrinkage adjustment, and surgical focus Journal of the American College of Surgeons. J Am Coll Surg. 2013;217:336-346.
21. Shiloach M, Frencher SK, Jr, Steeger JE, et al. Toward robust information: data quality and inter-rater reliability in the American College of Surgeons National Surgical Quality Improvement Program. J Am Coll Surg. 2010;210:6-16.
22. Bilimoria KY, Stewart AK, Winchester DP, et al. The National Cancer Data Base: a powerful initiative to improve cancer care in the United States. Ann Surg Oncol. 2008;15:683-690.
23. American College of Surgeons, Cancer Programs. The National Cancer Data Base Participant User Files, http://www.facs.org/cancer/ncdb/. Accessed June 20, 2013.
24. American Medical Association. Current Procedural Terminology. Chicago, IL: American Medical Association; 2013.
25. Department of Health and Human Services. The International Classification of Diseases, 9th revised, clinical modification: ICD-9 CM. Washington, DC: Government Printing Office; 1998.
26. International Classification of Disease for Oncology. 3rd ed. Geneva: World Health Organization; 2000.
27. AJCC Cancer Staging Manual, 7th ed. Chicago IL: Springer, 2010.
28. American College of Surgeons - National Surgical Quality Improvement Program: Chapter 4 - Variable Definitions.. Chicago, IL: American College of Surgeons; 2013.
29. Institute of Medicine of the National Academies. A national clinical trials system for the 21st century: reinvigorating the NCI Cooperative Group Program.. http://www.iom.edu/Reports/2010/A-National-Cancer-Clinical-Trials- System-for-the-21st-Century-Reinvigorating-the-NCI-Cooperative.aspx. Accessed June 24, 2011.
30. Abbott DE, Tzeng CW, Merkow RP, et al. The cost-effectiveness of neoadjuvant chemoradiation is superior to a surgery-first approach in the treatment of pancreatic head adenocarcinoma. Ann Surg Oncol. 2013;20:S500-S508.