Application of platelet-rich plasma and platelet-rich fibrin in fat grafting: Basic science and literature review

Tissue Engineering - Part B: Reviews

Volumn 20, Issue 4, 2014, Pages 267-276

  Liao, Han Tsung ^a,b   Marra, Kacey G ^a,c,d   Rubin, J Peter ^a,c,d  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b CHANG GUNG UNIVERSITY   (Taiwan)

^c University of Pittsburgh   (United States)

^d UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL ACTIVATION; PLASMA (HUMAN); STEM CELLS; TISSUE REGENERATION;

ADIPOSE DERIVED STEM CELLS; EPIDERMAL GROWTH FACTORS; MUSCULO-SKELETAL INJURIES; PLATELET-DERIVED GROWTH FACTORS; PLATELET-RICH PLASMA; POSSIBLE MECHANISMS; TRANSFORMING GROWTH FACTORS; VASCULAR ENDOTHELIAL GROWTH FACTOR;

PLATELETS;

GROWTH FACTOR; FIBRIN; SIGNAL PEPTIDE;

ADIPOCYTE; ADIPOSE DERIVED STEM CELL; CLINICAL RESEARCH; FAT GRAFTING; GRAFT SURVIVAL; HEMATOLOGICAL PROCEDURE; HUMAN; NONHUMAN; PLATELET RICH FIBRIN; PRESERVATION; PRIORITY JOURNAL; PROADIPOCYTE; REVIEW; THROMBOCYTE ACTIVATION; THROMBOCYTE RICH PLASMA; TISSUE TRANSPLANTATION; ADIPOSE TISSUE; ANIMAL; METABOLISM; PLASMA; STEM CELL; THROMBOCYTE; TRANSPLANTATION;

ADIPOCYTES; ADIPOSE TISSUE; ANIMALS; BLOOD PLATELETS; FIBRIN; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; PLASMA; STEM CELLS;

EID: 84905581876     PISSN: 19373368     EISSN: 19373376     Source Type: Journal    
DOI: 10.1089/ten.teb.2013.0317     Document Type: Review

References (57)

1. Pinski, K.S., and Roenigk, H.H., Jr. Autologous fat transplantation. Long-Term follow-up. J Dermatol Surg Oncol 18, 179, 1992
2. Kaufman, M.R., Bradley, J.P., Dickinson, B., Heller, J.B., Wasson, K., O'Hara, C., Huang, C., Gabbay, J., Ghadjar, K., and Miller, T.A. Autologous fat transfer national consensus survey: Trends in techniques for harvest, preparation, and application, and perception of short-And long-Term results. Plast Reconstr Surg 119, 323, 2007
3. Yoshimura, K., Sato, K., Aoi, N., Kurita, M., Hirohi, T., and Harii, K. Cell-Assisted lipotransfer for cosmetic breast augmentation: Supportive use of adipose-derived stem/stromal cells. Aesthetic Plast Surg 32, 48, 2008; discussion 56-57
4. Yoshimura, K., Sato, K., Aoi, N., Kurita, M., Inoue, K., Suga, H., Eto, H., Kato, H., Hirohi, T., and Harii, K. Cell-Assisted lipotransfer for facial lipoatrophy: Efficacy of clinical use of adipose-derived stem cells. Dermatol Surg 34, 1178, 2008
5. Chung, C.W., Marra, K.G., Li, H., Leung, A.S., Ward, D.H., Tan, H., Kelmendi-Doko, A., and Rubin, J.P. VEGF microsphere technology to enhance vascularization in fat grafting. Ann Plast Surg 69, 213, 2012
6. Lu, F., Li, J., Gao, J., Ogawa, R., Ou, C., Yang, B., and Fu, B. Improvement of the survival of human autologous fat transplantation by using VEGF-Transfected adipose-derived stem cells. Plast Reconstr Surg 124, 1437, 2009
7. Yuksel, E., Weinfeld, A.B., Cleek, R., Wamsley, S., Jensen, J., Boutros, S., Waugh, J.M., Shenaq, S.M., and Spira, M. Increased free fat-graft survival with the long-Term, local delivery of insulin, insulin-like growth factor-I, and basic fibroblast growth factor by PLGA/PEG microspheres. Plast Reconstr Surg 105, 1712, 2000
8. Hamed, S., Egozi, D., Kruchevsky, D., Teot, L., Gilhar, A., and Ullmann, Y. Erythropoietin improves the survival of fat tissue after its transplantation in nude mice. PLoS One 5, e13986, 2010
9. Eppley, B.L., Pietrzak, W.S., and Blanton, M. Platelet-rich plasma: A review of biology and applications in plastic surgery. Plast Reconstr Surg 118, 147e, 2006
10. Kim, E.S., Kim, J.J., and Park, E.J. Angiogenic factor-enriched platelet-rich plasma enhances in vivo bone formation around alloplastic graft material. J Adv Prosthodont 2, 7, 2010
11. Marx, R.E. Platelet-rich plasma: Evidence to support its use. J Oral Maxillofac Surg 62, 489, 2004
12. Marx, R.E., Carlson, E.R., Eichstaedt, R.M., Schimmele, S.R., Strauss, J.E., and Georgeff, K.R. Platelet-rich plasma: Growth factor enhancement for bone grafts. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 85, 638, 1998
13. Pietramaggiori, G., Kaipainen, A., Czeczuga, J.M., Wagner, C.T., and Orgill, D.P. Freeze-dried platelet-rich plasma shows beneficial healing properties in chronic wounds. Wound Repair Regen 14, 573, 2006
14. Foster, T.E., Puskas, B.L., Mandelbaum, B.R., Gerhardt, M.B., and Rodeo, S.A. Platelet-rich plasma: From basic science to clinical applications. Am J Sports Med 37, 2259, 2009
15. Sommeling, C.E., Heyneman, A., Hoeksema, H., Verbelen, J., Stillaert, F.B., and Monstrey, S. The use of platelet-rich plasma in plastic surgery: A systematic review. J Plast Reconstr Aesthet Surg 66, 301, 2013
16. Cervelli, V., Scioli, M.G., Gentile, P., Doldo, E., Bonanno, E., Spagnoli, L.G., and Orlandi, A. Platelet-rich plasma greatly potentiates insulin-induced adipogenic differentiation of human adipose-derived stem cells through a serine/threonine kinase Akt-dependent mechanism and promotes clinical fat graft maintenance. Stem Cells Transl Med 1, 206, 2012
17. Gentile, P., Di Pasquali, C., Bocchini, I., Floris, M., Eleonora, T., Fiaschetti, V., Floris, R., and Cervelli, V. Breast reconstruction with autologous fat graft mixed with platelet-rich plasma. Surg Innov 20, 370, 2013
18. Oh, D.S., Cheon, Y.W., Jeon, Y.R., and Lew, D.H. Activated platelet-rich plasma improves fat graft survival in nude mice: A pilot study. Dermatol Surg 37, 619, 2011
19. Pires Fraga, M.F., Nishio, R.T., Ishikawa, R.S., Perin, L.F., Helene, A., Jr., and Malheiros, C.A. Increased survival of free fat grafts with platelet-rich plasma in rabbits. J Plast Reconstr Aesthet Surg 63, e818, 2010
20. Por, Y.C., Yeow, V.K., Louri, N., Lim, T.K., Kee, I., and Song, I.C. Platelet-rich plasma has no effect on increasing free fat graft survival in the nude mouse. J Plast Reconstr Aesthet Surg 62, 1030, 2009
21. Rodriguez-Flores, J., Palomar-Gallego, M.A., Enguita-Valls, A.B., Rodriguez-Peralto, J.L., and Torres, J. Influence of platelet-rich plasma on the histologic characteristics of the autologous fat graft to the upper lip of rabbits. Aesthetic Plast Surg 35, 480, 2011
22. Nakamura, S., Ishihara, M., Takikawa, M., Murakami, K., Kishimoto, S., Yanagibayashi, S., Kubo, S., Yamamoto, N., and Kiyosawa, T. Platelet-rich plasma (PRP) promotes survival of fat-grafts in rats. Ann Plast Surg 65, 101, 2010
23. Jin, R., Zhang, L., and Zhang, Y.G. Does platelet-rich plasma enhance the survival of grafted fat?. An update review. Int J Clin Exp Med 6, 252, 2013
24. Pietrzak, W.S., and Eppley, B.L. Platelet rich plasma: Biology and new technology. J Craniofac Surg 16, 1043, 2005
25. Franco, D., Franco, T., Schettino, A.M., Filho, J.M., and Vendramin, F.S. Protocol for obtaining platelet-rich plasma (PRP), platelet-poor plasma (PPP), and thrombin for autologous use. Aesthetic Plast Surg 36, 1254, 2012
26. Efeoglu, C., Akcay, Y.D., and Erturk, S. A modified method for preparing platelet-rich plasma: An experimental study. J Oral Maxillofac Surg 62, 1403, 2004
27. Dugrillon, A., Eichler, H., Kern, S., and Kluter, H. Autologous concentrated platelet-rich plasma (cPRP) for local application in bone regeneration. Int J Oral Maxillofac Surg 31, 615, 2002
28. Weibrich, G., Kleis, W.K., Streckbein, P., Moergel, M., Hitzler, W.E., and Hafner, G. Comparison of point-ofcare methods for preparation of platelet concentrate (platelet-rich plasma). Int J Oral Maxillofac Implants 27, 762, 2012
29. Weibrich, G., Kleis, W.K., Hafner, G., and Hitzler, W.E. Growth factor levels in platelet-rich plasma and correlations with donor age, sex, and platelet count. J Craniomaxillofac Surg 30, 97, 2002
30. Sell, S.A., Wolfe, P.S., Ericksen, J.J., Simpson, D.G., and Bowlin, G.L. Incorporating platelet-rich plasma into electrospun scaffolds for tissue engineering applications. Tissue Eng Part A 17, 2723, 2011
31. Eppley, B.L., Woodell, J.E., and Higgins, J. Platelet quantification and growth factor analysis from platelet-rich plasma: Implications for wound healing. Plast Reconstr Surg 114, 1502, 2004
32. Chan, C.W., McCulley, S.J., and Macmillan, R.D. Autologous fat transfer-A review of the literature with a focus on breast cancer surgery. J Plast Reconstr Aesthet Surg 61, 1438, 2008
33. Ellenbogen, R. Autologous fat injection. Plast Reconstr Surg 88, 543, 1991
34. Ullmann, Y., Hyams, M., Ramon, Y., Beach, D., Peled, I.J., and Lindenbaum, E.S. Enhancing the survival of aspirated human fat injected into nude mice. Plast Reconstr Surg 101, 1940, 1998
35. Eto, H., Kato, H., Suga, H., Aoi, N., Doi, K., Kuno, S., and Yoshimura, K. The fate of adipocytes after nonvascularized fat grafting: Evidence of early death and replacement of adipocytes. Plast Reconstr Surg 129, 1081, 2012
36. Kakudo, N., Minakata, T., Mitsui, T., Kushida, S., Notodihardjo, F.Z., and Kusumoto, K. Proliferation-promoting effect of platelet-rich plasma on human adipose-derived stem cells and human Dermal fibroblasts. Plast Reconstr Surg 122, 1352, 2008
37. Liu, H.Y., Wu, A.T., Tsai, C.Y., Chou, K.R., Zeng, R., Wang, M.F., Chang, W.C., Hwang, S.M., Su, C.H., and Deng, W.P. The balance between adipogenesis and osteogenesis in bone regeneration by platelet-rich plasma for age-related osteoporosis. Biomaterials 32, 6773, 2011
38. Fukaya, Y., Kuroda, M., Aoyagi, Y., Asada, S., Kubota, Y., Okamoto, Y., Nakayama, T., Saito, Y., Satoh, K., and Bujo, H. Platelet-rich plasma inhibits the apoptosis of highly adipogenic homogeneous preadipocytes in an in vitro culture system. Exp Mol Med 44, 330, 2012
39. Camp, H.S., and Tafuri, S.R. Regulation of peroxisome proliferator-Activated receptor gamma activity by mitogenactivated protein kinase. J Biol Chem 272, 10811, 1997
40. Tontonoz, P., Hu, E., and Spiegelman, B.M. Stimulation of adipogenesis in fibroblasts by PPAR gamma 2, a lipid-Activated transcription factor. Cell 79, 1147, 1994
41. Kumar, A., Ruan, M., Clifton, K., Syed, F., Khosla, S., and Oursler, M.J. TGF-beta mediates suppression of adipogenesis by estradiol through connective tissue growth factor induction. Endocrinology 153, 254, 2012
42. Bachmeier, M., and Loffler, G. The effect of platelet-derived growth factor and adipogenic hormones on the expression of CCAAT/enhancer-binding proteins in 3T3-L1 cells in serum-free conditions. Eur J Biochem 243, 128, 1997
43. Staiger, H., and Loffler, G. The role of PDGF-dependent suppression of apoptosis in Differentiating 3T3-L1 preadipocytes. Eur J Cell Biol 77, 220, 1998
44. Craft, R.O., Rophael, J., Morrison, W.A., Vashi, A.V., Mitchell, G.M., and Penington, A.J. Effect of local, long-Term delivery of platelet-derived growth factor (PDGF) on injected fat graft survival in severe combined immunodeficient (SCID) mice. J Plast Reconstr Aesthet Surg 62, 235, 2009
45. Rophael, J.A., Craft, R.O., Palmer, J.A., Hussey, A.J., Thomas, G.P., Morrison, W.A., Penington, A.J., and Mitchell, G.M. Angiogenic growth factor synergism in a murine tissue engineering model of angiogenesis and adipogenesis. Am J Pathol 171, 2048, 2007
46. Salgarello, M., Visconti, G., and Rusciani, A. Breast fat grafting with platelet-rich plasma: A comparative clinical study and current state of the art. Plast Reconstr Surg 127, 2176, 2011
47. Gentile, P., Orlandi, A., Scioli, M.G., Di Pasquali, C., Bocchini, I., Curcio, C.B., Floris, M., Fiaschetti, V., Floris, R., and Cervell, V. A comparative translational study: The combined use of enhanced stromal vascular fraction and platelet-rich plasma improves fat grafting maintenance in breast reconstruction. Stem Cells Transl Med 1, 341, 2012
48. Herold, C., Ueberreiter, K., Busche, M.N., and Vogt, P.M. Autologous fat transplantation: Volumetric tools for estimation of volume survival. A systematic review. Aesthetic Plast Surg 37, 380, 2013
49. Dohan, D.M., Choukroun, J., Diss, A., Dohan, S.L., Dohan, A.J., Mouhyi, J., and Gogly, B. Platelet-rich fibrin (PRF): A second-generation platelet concentrate. Part I: Technological concepts and evolution. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 101, e37, 2006
50. Liu, B., Tan, X.Y., Liu, Y.P., Xu, X.F., Li, L., Xu, H.Y., An, R., and Chen, F.M. The adjuvant use of stromal vascular fraction and platelet-rich fibrin for autologous adipose tissue transplantation. Tissue Eng Part C Methods 19, 1, 2013
51. He, L., Lin, Y., Hu, X., Zhang, Y., and Wu, H. A comparative study of platelet-rich fibrin (PRF) and platelet-rich plasma (PRP) on the effect of proliferation and differentiation of rat osteoblasts in vitro. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 108, 707, 2009
52. Keyhan, S.O., Hemmat, S., Badri, A.A., Abdeshahzadeh, A., and Khiabani, K. Use of platelet-rich fibrin and platelet-rich plasma in combination with fat graft: Which is more effective during facial lipostructure?. J Oral Maxillofac Surg 71, 610, 2013
53. Liu, Y., Zhou, Y., Feng, H., Ma, G.E., and Ni, Y. Injectable tissue-engineered bone composed of human adipose-derived stromal cells and platelet-rich plasma. Biomaterials 29, 3338, 2008
54. Kurita, J., Miyamoto, M., Ishii, Y., Aoyama, J., Takagi, G., Naito, Z., Tabata, Y., Ochi, M., and Shimizu, K. Enhanced vascularization by controlled release of platelet-rich plasma impregnated in biodegradable gelatin hydrogel. Ann Thorac Surg 92, 837; discussion 844, 2011
55. Matsumoto, D., Sato, K., Gonda, K., Takaki, Y., Shigeura, T., Sato, T., Aiba-Kojima, E., Iizuka, F., Inoue, K., Suga, H., and Yoshimura, K. Cell-Assisted lipotransfer: Supportive use of human adipose-derived cells for soft tissue augmentation with lipoinjection. Tissue Eng 12, 3375, 2006
56. Tsay, R.C., Vo, J., Burke, A., Eisig, S.B., Lu, H.H., Landesberg, R. Differential growth factor retention by platelet-rich plasma composites. J Oral Maxillofac Surg 63, 521, 2005
57. Huang, Q., Wang, Y.D., Wu, T., Jiang, S., Hu, Y.L., Pei, G.X. Preliminary separation of the growth factors in platelet-rich plasma: Effects on the proliferation of human marrow-derived mesenchymal stem cells. Chin Med J (Engl) 122, 83, 2009