Revisiting the first long-term culture of antigen-specific cytotoxic T cells

Frontiers in Immunology

Volumn 5, Issue MAY, 2014, Pages

  Smith, Kendall A ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

Cytotoxic T lymphocytes; Lymphocyte conditioned media

Indexed keywords

CONCANAVALIN A;

CELL CULTURE; CELL GROWTH; CELL PROLIFERATION; CYTOTOXIC T LYMPHOCYTE; HUMAN; LEUKEMIA CELL; NONHUMAN; NOTE;

EID: 84905491180     PISSN: None     EISSN: 16643224     Source Type: Journal    
DOI: 10.3389/fimmu.2014.00194     Document Type: Note

References (18)

1. Gillis S, Smith KA. Long term culture of tumour-specific cytotoxic T cells. Nature (1977) 268(5616):154-6. doi:10.1038/268154a0
2. McDonald H, Engers H, Cerottini J, Bruner BT. Generation of cytotoxic T lymphocytes in vitro. II. The effect of repeated exposure to alloantigens on the cytotoxic activity of long-term mixed leukocyte cultures. J Exp Med (1974) 140:718-30. doi:10.1084/jem.140.3.718
3. Svedmyr E. Long-term maintenance in vitro of human T cells by repeated exposure to the same stimulator cells. Scand J Immunol (1975) 4:421-7. doi:10.1111/j.1365-3083.1975.tb02647.x
4. Ben-Sasson S, Paul W, Shevach E, Green I. In vitro selection and extended culture of antigen-specific T lymphocytes. I. Description of selection procedure and initial characterization of selected cells. J Exp Med (1975) 142:90-105. doi:10.1084/jem.142.1.90
5. Dennert G, De Rose M. Continuously proliferating T killer cells specific for H-2b targets: selection and characterization. J Immunol (1976) 116(6):1601-6.
6. Kasakura S, Lowenstein L. A factor stimulating DNA synthesis derived from the medium of leukocyte cultures. Nature (1965) 208:794-5. doi:10.1038/208794a0
7. Gordon J, MacLean LD. A lymphocyte-stimulating factor produced in vitro. Nature (1965) 208:795-6. doi:10.1038/208795a0
8. Bach F, Alter B, Solliday S, Zoschke D, Janis M. Lymphocyte reactivity in vitro II. Soluble reconstituting factor permitting response of purified lymphocytes. Cell Immunol (1970) 1:219-27. doi:10.1016/0008-8749(70)90009-2
9. Dutton RW, McCarthy MM, Mishell RI, Raidt DJ. Cell components in the immune response. IV. Relationships and possible interactions. Cell Immunol (1970) 1:196-206. doi:10.1016/0008-8749(70)90007-9
10. Hoffman M, Dutton R. Immune response restoration with macrophage culture supernatants. Science (1971) 172:1047-8. doi:10.1126/science.172.3987.1047
11. Gery I, Gershon RK, Waksman B. Potentiation of the T-lymphocyte response to mitogens I. The responding cell. J Exp Med (1972) 136:128-42. doi:10.1084/jem.136.1.143
12. Gery I, Waksman BH. Potentiation of the T-lymphocyte response to mitogens: the cellular source of potentiating mediators. J Exp Med (1972) 136:143-55. doi:10.1084/jem.136.1.143
13. Schimpl A, Wecker E. Replacement of T cell function by a T cell product. Nat New Biol (1972) 237:15-7. doi:10.1038/newbio237015a0
14. Cline M, Golde D. Production of colony-stimulating activity by human lymphocytes. Nature (1974) 248:703-4. doi:10.1038/248703a0
15. Morgan DA, Ruscetti FW, Gallo R. Selective in vitro growth of T lymphocytes from normal human bone marrows. Science (1976) 193(4257):1007-8. doi:10.1126/science.181845
16. Gillis S, Smith K. In vitro generation of tumor-specific cytotoxic lymphocytes. Secondary allogeneic mixed tumor lymphocyte culture of normal murine spleen cells. J Exp Med (1977) 146:468-82. doi:10.1084/jem.146.2.468
17. Hayflick L, Moorhead P. The serial cultivation of human diploid cell strains. Exp Cell Res (1961) 25:585-621. doi:10.1016/0014-4827(61)90192-6
18. Baker PE, Gillis S, Smith KA. Monoclonal cytolytic T-cell lines. J Exp Med (1979) 149(1):273-8. doi:10.1084/jem.149.1.273