Robustness and Evolvability of the Human Signaling Network

PLoS Computational Biology

Volumn 10, Issue 7, 2014, Pages

  Kim, Junil ^a   Vandamme, Drieke ^b   Kim, Jeong Rae ^a,c   Munoz, Amaya Garcia ^b   Kolch, Walter ^b   Cho, Kwang Hyun ^a  

^a Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

^b UNIVERSITY COLLEGE DUBLIN   (Ireland)

^c University of Seoul   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ONCOGENIC VIRUSES; SIGNALING;

BOOLEAN NETWORK MODELS; DRUG TARGETS; EVOLVABILITY; EVOLVABLE; EXTERNAL PERTURBATIONS; HIGH ROBUSTNESS; INTERNAL PERTURBATION; LANDSCAPE ANALYSIS; PROPERTY; SIGNALING NETWORKS;

GENES;

ARTICLE; CONTROLLED STUDY; DRUG TARGETING; EVOLUTIONARY RATE; FEEDBACK SYSTEM; HEK293 CELL LINE; HELA CELL LINE; HUMAN; HUMAN CELL; IMMUNE SYSTEM; INFORMATION SCIENCE; ONCOGENE; PHYSICAL PARAMETERS; ROBUSTNESS; SCORING SYSTEM; SIGNAL TRANSDUCTION; STATISTICAL MODEL; ALGORITHM; BIOLOGICAL MODEL; DRUG DEVELOPMENT; GENETICS; MOLECULAR EVOLUTION; PHYSIOLOGY;

ALGORITHMS; DRUG DISCOVERY; EVOLUTION, MOLECULAR; HUMANS; MODELS, BIOLOGICAL; SIGNAL TRANSDUCTION;

EID: 84905455416     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1003763     Document Type: Article

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