메뉴 건너뛰기




Volumn 27, Issue 3, 2013, Pages 208-214

Genome-wide analysis of runs of homozygosity identifies new susceptibility regions of lung cancer in Han Chinese

Author keywords

Genome wide association study; Lung cancer; Runs of homozygosity (ROHs)

Indexed keywords

ADULT; ARTICLE; CANCER RISK; CANCER SUSCEPTIBILITY; CONTROLLED STUDY; FEMALE; GENETIC ASSOCIATION; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOME ANALYSIS; HAN CHINESE; HOMOZYGOSITY; HUMAN; LARGE CELL CARCINOMA; LUNG ADENOCARCINOMA; LUNG CANCER; LUNG SQUAMOUS CELL CARCINOMA; MAJOR CLINICAL STUDY; MALE; MIXED TUMOR; POPULATION BASED CASE CONTROL STUDY; RISK ASSESSMENT; SINGLE NUCLEOTIDE POLYMORPHISM; SMALL CELL LUNG CANCER;

EID: 84905446110     PISSN: 16748301     EISSN: None     Source Type: Journal    
DOI: 10.7555/JBR.27.20130017     Document Type: Article
Times cited : (22)

References (44)
  • 2
    • 79953224060 scopus 로고    scopus 로고
    • Genetics of lung-cancer susceptibility
    • Brennan P, Hainaut P, Boffetta P. Genetics of lung-can- cer susceptibility. Lancet Oncol 2011; 12: 399-408.
    • (2011) Lancet Oncol , vol.12 , pp. 399-408
    • Brennan, P.1    Hainaut, P.2    Boffetta, P.3
  • 3
    • 41649103682 scopus 로고    scopus 로고
    • A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25
    • Hung RJ, McKay JD, Gaborieau V, Boffetta P, Hashibe M, Zaridze D, et al. A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25. Nature 2008; 452: 633-7.
    • (2008) Nature , vol.452 , pp. 633-637
    • Hung, R.J.1    McKay, J.D.2    Gaborieau, V.3    Boffetta, P.4    Hashibe, M.5    Zaridze, D.6
  • 6
    • 72149129508 scopus 로고    scopus 로고
    • A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma
    • Landi MT, Chatterjee N, Yu K, Goldin LR, Goldstein AM, Rotunno M, et al. A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma. The American Journal of Human Genetics 2009; 85: 679-91.
    • (2009) The American Journal of Human Genetics , vol.85 , pp. 679-691
    • Landi, M.T.1    Chatterjee, N.2    Yu, K.3    Goldin, L.R.4    Goldstein, A.M.5    Rotunno, M.6
  • 7
    • 77957551804 scopus 로고    scopus 로고
    • The 5p15. 33 locus is associated with risk of lung adenocarcinoma in never-smoking females in Asia.
    • Hsiung CA, Lan Q, Hong YC, Chen CJ, Hosgood HD, Chang IS, et al. The 5p15. 33 locus is associated with risk of lung adenocarcinoma in never-smoking females in Asia. PLoS Genet 2010; 6: e1001051.
    • (2010) PLoS Genet , vol.6
    • Hsiung, C.A.1    Lan, Q.2    Hong, Y.C.3    Chen, C.J.4    Hosgood, H.D.5    Chang, I.S.6
  • 8
    • 77957588624 scopus 로고    scopus 로고
    • Variation in TP63 is associated with lung adenocarcinoma susceptibility in Japanese and Korean populations
    • Miki D, Kubo M, Takahashi A, Yoon KA, Kim J, Lee GK, et al. Variation in TP63 is associated with lung adenocarcinoma susceptibility in Japanese and Korean populations. Nat Genet 2010; 42: 893-6.
    • (2010) Nat Genet , vol.42 , pp. 893-896
    • Miki, D.1    Kubo, M.2    Takahashi, A.3    Yoon, K.A.4    Kim, J.5    Lee, G.K.6
  • 9
    • 79960929526 scopus 로고    scopus 로고
    • A genome-wide association study identifies two new lung cancer susceptibility loci at 13q1. 12 and 22q12. 2 in Han Chinese.
    • Hu Z, Wu C, Shi Y, Guo H, Zhao X, Yin Z, et al. A genome-wide association study identifies two new lung cancer susceptibility loci at 13q12. 12 and 22q12. 2 in Han Chinese. Nat Genet 2011; 43: 792-6.
    • (2011) Nat Genet , vol.43 , pp. 792-796
    • Hu, Z.1    Wu, C.2    Shi, Y.3    Guo, H.4    Zhao, X.5    Yin, Z.6
  • 10
    • 84864416630 scopus 로고    scopus 로고
    • A genome-wide association study identifies two new susceptibility loci for lung adenocarcinoma in the Japanese population
    • Shiraishi K, Kunitoh H, Daigo Y, Takahashi A, Goto K, Sakamoto H, et al. A genome-wide association study identifies two new susceptibility loci for lung adenocar- cinoma in the Japanese population. Nat Genet 2012; 44: 900-3.
    • (2012) Nat Genet , vol.44 , pp. 900-903
    • Shiraishi, K.1    Kunitoh, H.2    Daigo, Y.3    Takahashi, A.4    Goto, K.5    Sakamoto, H.6
  • 11
    • 84868156549 scopus 로고    scopus 로고
    • Influence of common genetic variation on lung cancer risk: meta-analysis of 14 900 cases and 29 485 controls
    • Timofeeva MN, Hung RJ, Rafnar T, Christiani DC, Field JK, Bickeboller H, et al. Influence of common genetic variation on lung cancer risk: meta-analysis of 14 900 cases and 29 485 controls. Hum Mol Genet 2012; 21: 4980-95.
    • (2012) Hum Mol Genet , vol.21 , pp. 4980-4995
    • Timofeeva, M.N.1    Hung, R.J.2    Rafnar, T.3    Christiani, D.C.4    Field, J.K.5    Bickeboller, H.6
  • 12
    • 33144460067 scopus 로고    scopus 로고
    • Extended tracts of homozygosity in outbred human populations
    • Gibson J, Morton NE, Collins A. Extended tracts of homozygosity in outbred human populations. Hum Mol Genet 2006; 15: 789-95.
    • (2006) Hum Mol Genet , vol.15 , pp. 789-795
    • Gibson, J.1    Morton, N.E.2    Collins, A.3
  • 13
    • 38949169544 scopus 로고    scopus 로고
    • Study of regions of extended homozygosity provides a powerful method to explore haplotype structure of human populations
    • Curtis D, Vine A, Knight J. Study of regions of extended homozygosity provides a powerful method to explore haplotype structure of human populations. Ann Hum Genet 2008; 72: 261-78.
    • (2008) Ann Hum Genet , vol.72 , pp. 261-278
    • Curtis, D.1    Vine, A.2    Knight, J.3
  • 14
    • 77958159076 scopus 로고    scopus 로고
    • Genomic and geographic distribution of SNP-defined runs of homozygosity in Europeans
    • Nothnagel M, Lu TT, Kayser M, Krawczak M. Genomic and geographic distribution of SNP-defined runs of homozygosity in Europeans. Hum Mol Genet 2010; 19: 2927-35.
    • (2010) Hum Mol Genet , vol.19 , pp. 2927-2935
    • Nothnagel, M.1    Lu, T.T.2    Kayser, M.3    Krawczak, M.4
  • 15
    • 78651228788 scopus 로고    scopus 로고
    • Regions of homozygosity and their impact on complex diseases and traits
    • Ku CS, Naidoo N, Teo SM, Pawitan Y. Regions of homozygosity and their impact on complex diseases and traits. Hum Genet 2011; 129: 1-15.
    • (2011) Hum Genet , vol.129 , pp. 1-15
    • Ku, C.S.1    Naidoo, N.2    Teo, S.M.3    Pawitan, Y.4
  • 17
    • 70349736105 scopus 로고    scopus 로고
    • Colorectal cancer risk is not associated with increased levels of homozygosity in a population from the United Kingdom
    • Spain SL, Cazier JB, Houlston R, Carvajal-Carmona L, Tomlinson I. Colorectal cancer risk is not associated with increased levels of homozygosity in a population from the United Kingdom. Cancer Res 2009; 69: 7422.
    • (2009) Cancer Res , vol.69 , pp. 7422
    • Spain, S.L.1    Cazier, J.B.2    Houlston, R.3    Carvajal-Carmona, L.4    Tomlinson, I.5
  • 19
    • 77954955955 scopus 로고    scopus 로고
    • Risk of breast and prostate cancer is not associated with increased homozygosity in outbred populations
    • Enciso-Mora V, Hosking FJ, Houlston RS. Risk of breast and prostate cancer is not associated with increased homozygosity in outbred populations. Eur J Hum Genet 2010; 18: 909-14.
    • (2010) Eur J Hum Genet , vol.18 , pp. 909-914
    • Enciso-Mora, V.1    Hosking, F.J.2    Houlston, R.S.3
  • 20
    • 77953942939 scopus 로고    scopus 로고
    • Genome-wide homozygosity signatures and childhood acute lymphoblastic leukemia risk
    • Hosking FJ, Papaemmanuil E, Sheridan E, Kinsey SE, Lightfoot T, Roman E, et al. Genome-wide homozygosity signatures and childhood acute lymphoblastic leukemia risk. Blood 2010; 115: 4472-7.
    • (2010) Blood , vol.115 , pp. 4472-4477
    • Hosking, F.J.1    Papaemmanuil, E.2    Sheridan, E.3    Kinsey, S.E.4    Lightfoot, T.5    Roman, E.6
  • 22
    • 84863242881 scopus 로고    scopus 로고
    • Integrative genomic analysis reveals extended germline homozygosity with lung cancer risk in the PLCO cohort
    • Orloff MS, Zhang L, Bebek G, Eng C. Integrative genomic analysis reveals extended germline homozygosity with lung cancer risk in the PLCO cohort. PLoS One 2012; 7: e31975.
    • (2012) PLoS One , vol.7
    • Orloff, M.S.1    Zhang, L.2    Bebek, G.3    Eng, C.4
  • 23
    • 84864673541 scopus 로고    scopus 로고
    • Colorectal cancer risk is not associated with increased levels of homozygosity in Saudi Arabia
    • Apr 5. [Epub ahead of print].
    • Siraj AK, Khalak HG, Sultana M, Al-Rasheed M, Bavi P, Al-Sanea N, et al. Colorectal cancer risk is not associated with increased levels of homozygosity in Saudi Arabia. Genet Med 2012 Apr 5. doi: 10.1038/gim.2012.27. [Epub ahead of print].
    • (2012) Genet Med
    • Siraj, A.K.1    Khalak, H.G.2    Sultana, M.3    Al-Rasheed, M.4    Bavi, P.5    Al-Sanea, N.6
  • 24
    • 84860009658 scopus 로고    scopus 로고
    • A genome-wide homozygosity association study identifies runs of homozygosity associated with rheumatoid rrthritis in the human major histocompatibility complex
    • Yang HC, Chang LC, Liang YJ, Lin CH, Wang PL. A genome-wide homozygosity association study identifies runs of homozygosity associated with rheumatoid rrthritis in the human major histocompatibility complex. PLoS One 2012; 7: e34840.
    • (2012) PLoS One , vol.7
    • Yang, H.C.1    Chang, L.C.2    Liang, Y.J.3    Lin, C.H.4    Wang, P.L.5
  • 28
    • 0030305457 scopus 로고    scopus 로고
    • A language for data analysis and graphics
    • Ihaka R, Gentleman R. R: A language for data analysis and graphics. J Comput Graph Stat 1996: 299-314.
    • (1996) J Comput Graph Stat , pp. 299-314
    • Ihaka, R.1    Gentleman, R.R.2
  • 29
    • 80052686016 scopus 로고    scopus 로고
    • Quantification of Inbreeding due to distant ancestors and its detection using dense single nucleotide polymorphism data
    • Keller MC, Visscher PM, Goddard ME. Quantification of Inbreeding due to distant ancestors and its detection using dense single nucleotide polymorphism data. Genetics 2011; 189: 237-49.
    • (2011) Genetics , vol.189 , pp. 237-249
    • Keller, M.C.1    Visscher, P.M.2    Goddard, M.E.3
  • 30
    • 63449140483 scopus 로고    scopus 로고
    • Measures of autozygosity in decline: globalization, urbanization, and its implications for medical genetics
    • Nalls MA, Simon-Sanchez J, Gibbs JR, Paisan-Ruiz C, Bras JT, Tanaka T, et al. Measures of autozygosity in decline: globalization, urbanization, and its implications for medical genetics. PLoS Genet 2009; 5: e1000415.
    • (2009) PLoS Genet , vol.5
    • Nalls, M.A.1    Simon-Sanchez, J.2    Gibbs, J.R.3    Paisan-Ruiz, C.4    Bras, J.T.5    Tanaka, T.6
  • 32
    • 41149122075 scopus 로고    scopus 로고
    • Frequency of germline genomic homozygosity associated with cancer cases
    • Assié G, LaFramboise T, Platzer P, Eng C. Frequency of germline genomic homozygosity associated with cancer cases. JAMA 2008; 299: 1437-45.
    • (2008) JAMA , vol.299 , pp. 1437-1445
    • Assié, G.1    LaFramboise, T.2    Platzer, P.3    Eng, C.4
  • 33
    • 70249085939 scopus 로고    scopus 로고
    • Extended tracts of homozygosity identify novel candidate genes associated with late-onset Alzheimer's disease
    • Nalls M, Guerreiro R, Simon-Sanchez J, Bras J, Traynor B, Gibbs J, et al. Extended tracts of homozygosity identify novel candidate genes associated with late-onset Alzheimer's disease. Neurogenetics 2009; 10: 183-90.
    • (2009) Neurogenetics , vol.10 , pp. 183-190
    • Nalls, M.1    Guerreiro, R.2    Simon-Sanchez, J.3    Bras, J.4    Traynor, B.5    Gibbs, J.6
  • 34
    • 80054924102 scopus 로고    scopus 로고
    • Gene copy number aberrations are associated with survival in histologic subgroups of non-small cell lung cancer
    • Micke P, Edlund K, Holmberg L, Kultima HG, Mansouri L, Ekman S, et al. Gene copy number aberrations are associated with survival in histologic subgroups of non-small cell lung cancer. J Thorac Oncol 2011; 6: 1833-40.
    • (2011) J Thorac Oncol , vol.6 , pp. 1833-1840
    • Micke, P.1    Edlund, K.2    Holmberg, L.3    Kultima, H.G.4    Mansouri, L.5    Ekman, S.6
  • 35
    • 0035966322 scopus 로고    scopus 로고
    • Wnt/Frizzled activation of Rho regulates vertebrate gastrulation and requires a novel Formin homology protein Daam1
    • Habas R, Kato Y, He X. Wnt/Frizzled activation of Rho regulates vertebrate gastrulation and requires a novel Formin homology protein Daam1. Cell 2001; 107: 843-54.
    • (2001) Cell , vol.107 , pp. 843-854
    • Habas, R.1    Kato, Y.2    He, X.3
  • 36
    • 8844231037 scopus 로고    scopus 로고
    • Identification and comparative expression analyses of Daam genes in mouse and Xenopus
    • Nakaya M, Habas R, Biris K, Dunty WC, Kato Y, He X, et al. Identification and comparative expression analyses of Daam genes in mouse and Xenopus. Gene Expr Patterns 2004; 5: 97-105.
    • (2004) Gene Expr Patterns , vol.5 , pp. 97-105
    • Nakaya, M.1    Habas, R.2    Biris, K.3    Dunty, W.C.4    Kato, Y.5    He, X.6
  • 37
    • 84863597893 scopus 로고    scopus 로고
    • Planar polarity: A new player in both lung development and disease
    • Yates LL, Dean CH. Planar polarity: A new player in both lung development and disease. Organogenesis 2011; 7: 209-16.
    • (2011) Organogenesis , vol.7 , pp. 209-216
    • Yates, L.L.1    Dean, C.H.2
  • 38
    • 78751534204 scopus 로고    scopus 로고
    • Dishevelled-associated activator of morphogenesis 1 (Daam1) is required for heart morphogenesis
    • Li D, Hallett MA, Zhu W, Rubart M, Liu Y, Yang Z, et al. Dishevelled-associated activator of morphogenesis 1 (Daam1) is required for heart morphogenesis. Development 2011; 138: 303-15.
    • (2011) Development , vol.138 , pp. 303-315
    • Li, D.1    Hallett, M.A.2    Zhu, W.3    Rubart, M.4    Liu, Y.5    Yang, Z.6
  • 40
    • 25444516196 scopus 로고    scopus 로고
    • JAMP, a Jun N-terminal kinase 1 (JNK1)-associated membrane protein, regulates duration of JNK activity
    • Kadoya T, Khurana A, Tcherpakov M, Bromberg KD, Didier C, Broday L, et al. JAMP, a Jun N-terminal kinase 1 (JNK1)-associated membrane protein, regulates duration of JNK activity. Mol Cell Biol 2005; 25: 8619- 30.
    • (2005) Mol Cell Biol , vol.25 , pp. 8619-8630
    • Kadoya, T.1    Khurana, A.2    Tcherpakov, M.3    Bromberg, K.D.4    Didier, C.5    Broday, L.6
  • 41
    • 4644241746 scopus 로고    scopus 로고
    • The c-Jun NH2-terminal kinase is essential for epidermal growth factor expression during epidermal morphogenesis
    • USA
    • Weston CR, Wong A, Hall JP, Goad MEP, Flavell RA, Davis RJ. The c-Jun NH2-terminal kinase is essential for epidermal growth factor expression during epidermal morphogenesis. Proc Natl Acad Sci USA 2004; 101: 14114-9.
    • (2004) Proc Natl Acad Sci , vol.101 , pp. 14114-14119
    • Weston, C.R.1    Wong, A.2    Hall, J.P.3    Goad, M.E.P.4    Flavell, R.A.5    Davis, R.J.6
  • 42
    • 34247357465 scopus 로고    scopus 로고
    • c-Jun N-terminal kinase is activated in non-small-cell lung cancer and promotes neoplastic transformation in human bronchial epithelial cells
    • Khatlani T, Wislez M, Sun M, Srinivas H, Iwanaga K, Ma L, et al. c-Jun N-terminal kinase is activated in non-small-cell lung cancer and promotes neoplastic transformation in human bronchial epithelial cells. Oncogene 2006; 26: 2658-66.
    • (2006) Oncogene , vol.26 , pp. 2658-2666
    • Khatlani, T.1    Wislez, M.2    Sun, M.3    Srinivas, H.4    Iwanaga, K.5    Ma, L.6
  • 43
    • 0027497328 scopus 로고
    • Cloning and expression of alternative transcripts of a novel neuroendocrine-specific gene and identification of its 135-kDa translational product
    • Roebroek A, Van De Velde H, Van Bokhoven A, Broers J, Ramaekers F, Van de Ven W. Cloning and expression of alternative transcripts of a novel neuroendocrine-specific gene and identification of its 135-kDa translational product. J Biol Chem 1993; 268: 13439-47.
    • (1993) J Biol Chem , vol.268 , pp. 13439-13447
    • Roebroek, A.1    Van De Velde, H.2    Van Bokhoven, A.3    Broers, J.4    Ramaekers, F.5    Van De Ven, W.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.