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1
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0028296142
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Progression of aortic dilatation and the benefit of long-term beta-adrenergic blockade in Marfan's syndrome
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Landmark study on the effect of prophylactic β-blocker therapy on progression of aortic dilatation in MFS
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Shores J, Berger KR, Murphy EA, et al. Progression of aortic dilatation and the benefit of long-term beta-adrenergic blockade in Marfan's syndrome. N Engl J Med 1994;330:1335-41. Landmark study on the effect of prophylactic β-blocker therapy on progression of aortic dilatation in MFS.
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N Engl J Med
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Shores, J.1
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2
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0033614448
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Replacement of the aortic root in patients with Marfan's syndrome
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DOI 10.1056/NEJM199904293401702
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Gott VL, Greene PS, Alejo DE, et al. Replacement of the aortic root in patients with Marfan's syndrome. N Engl J Med 1999;340:1307-13. Landmark study on the value of prophylactic aortic root surgery in MFS. (Pubitemid 29196592)
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New England Journal of Medicine
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Gott, V.L.1
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Miller, D.C.6
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Laschinger, J.C.8
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Cabrol, C.E.A.11
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Coselli, J.S.13
David, T.E.14
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Kouchoukos, N.T.16
Turina, M.I.17
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3
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77956127537
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The revised Ghent nosology for the Marfan syndrome
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The latest nosology for the Marfan syndrome from 2010
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Loeys BL, Dietz HC, Braverman AC, et al. The revised Ghent nosology for the Marfan syndrome. J Med Genet 2010;47:476-85. The latest nosology for the Marfan syndrome from 2010.
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Loeys, B.L.1
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Distal aortic and peripheral arterial aneurysms in patients with Marfan syndrome
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Yetman, A.T.1
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5
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84894057868
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Should we systematically screen for peripheral arterial aneurysms in all patients with Marfan syndrome?
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Gaertner S, Alembik Y, Cordeanu EM, et al. Should we systematically screen for peripheral arterial aneurysms in all patients with Marfan syndrome? Int J Cardiol 2014;172:e94-5.
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Int J Cardiol
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A simple clinical model to estimate the probability of Marfan syndrome
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Sheikhzadeh S, Kusch ML, Rybczynski M, et al. A simple clinical model to estimate the probability of Marfan syndrome. QJM 2012;105:527-35.
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Sheikhzadeh, S.1
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7
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Two-dimensional echocardiographic aortic root dimensions in normal children and adults
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DOI 10.1016/0002-9149(89)90430-X
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Roman MJ, Devereux RB, Kramer-Fox R, et al. Two-dimensional echocardiographic aortic root dimensions in normal children and adults. Am J Cardiol 1989;64:507-12. This study provides one of the most commonly used equations for the calculation of z-scores of the aortic root in adults. (Pubitemid 19214582)
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American Journal of Cardiology
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Roman, M.J.1
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8
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80052640522
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Critical appraisal of the revised Ghent criteria for diagnosis of Marfan syndrome
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Radonic T, de Witte P, Groenink M, et al. Critical appraisal of the revised Ghent criteria for diagnosis of Marfan syndrome. Clin Genet 2011;80:346-53.
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9
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84866733874
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Normal limits in relation to age, body size and gender of two-dimensional echocardiographic aortic root dimensions in persons ≥15 years of age
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Provides two new equations for the calculation of z-scores of the aortic root. A high number of subjects were studied
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Devereux RB, de Simone G, Arnett DK, et al. Normal limits in relation to age, body size and gender of two-dimensional echocardiographic aortic root dimensions in persons ≥15 years of age. Am J Cardiol 2012;110:1189-94. Provides two new equations for the calculation of z-scores of the aortic root. A high number of subjects were studied.
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Am J Cardiol
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Devereux, R.B.1
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Analysis of phenotype and genotype information for the diagnosis of Marfan syndrome
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Sheikhzadeh S, Kade C, Keyser B, et al. Analysis of phenotype and genotype information for the diagnosis of Marfan syndrome. Clin Genet 2012;82:240-7.
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Sheikhzadeh, S.1
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11
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69249220259
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Identification of the minimal combination of clinical features in probands for efficient mutation detection in the FBN1 gene
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Stheneur C, Collod-Beroud G, Faivre L, et al. Identification of the minimal combination of clinical features in probands for efficient mutation detection in the FBN1 gene. Eur J Hum Genet 2009;17:1121-8.
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Eur J Hum Genet
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Stheneur, C.1
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Faivre, L.3
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12
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78649813429
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ESC guidelines for the management of grown-up congenital heart disease (new version 2010)
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Baumgartner H, Bonhoeffer P, De Groot NM, et al. ESC guidelines for the management of grown-up congenital heart disease (new version 2010). Eur Heart J 2010;31:2915-57.
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Eur Heart J
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Baumgartner, H.1
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13
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84880241924
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A systematic review of the pharmacological management of aortic root dilation in Marfan syndrome
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Comprehensive review of the pharmacological management of MFS. Does not include the results of the first large study on losartan
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Thakur V, Rankin KN, Hartling L, et al. A systematic review of the pharmacological management of aortic root dilation in Marfan syndrome. Cardiol Young 2013;23:568-81. Comprehensive review of the pharmacological management of MFS. Does not include the results of the first large study on losartan.
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Cardiol Young
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Thakur, V.1
Rankin, K.N.2
Hartling, L.3
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14
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33645672459
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Losartan, an AT1 antagonist, prevents aortic aneurysm in a mouse model of Marfan syndrome
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Landmark study on the effect of losartan in a mouse model of MFS. This study inspired a large number of ongoing clinical trials in humans
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Habashi JP, Judge DP, Holm TM, et al. Losartan, an AT1 antagonist, prevents aortic aneurysm in a mouse model of Marfan syndrome. Science 2006;312:117-21. Landmark study on the effect of losartan in a mouse model of MFS. This study inspired a large number of ongoing clinical trials in humans.
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Science
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Habashi, J.P.1
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15
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Angiotensin II blockade and aortic-root dilation in marfan's syndrome
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DOI 10.1056/NEJMoa0706585
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Brooke BS, Habashi JP, Judge DP, et al. Angiotensin II blockade and aortic-root dilation in Marfan' s syndrome. N Engl J Med 2008;358:2787-95. (Pubitemid 351930853)
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New England Journal of Medicine
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Brooke, B.S.1
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Dietz III, H.C.6
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16
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84888237597
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Losartan reduces aortic dilatation rate in adults with Marfan syndrome: A randomized controlled trial
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Encouraging results from the first prospective, randomised, open-label, multicentre trial on the effect of losartan on aortic dilatation in adult MFS patients
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Groenink M, den Hartog AW, Franken R, et al. Losartan reduces aortic dilatation rate in adults with Marfan syndrome: a randomized controlled trial. Eur Heart J 2013;34:3491-500. Encouraging results from the first prospective, randomised, open-label, multicentre trial on the effect of losartan on aortic dilatation in adult MFS patients.
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Eur Heart J
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Groenink, M.1
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79956322488
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Surgical management of aortic root disease in Marfan syndrome: A systematic review and meta-analysis
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Benedetto U, Melina G, Takkenberg JJ, et al. Surgical management of aortic root disease in Marfan syndrome: a systematic review and meta-analysis. Heart 2011;97:955-8.
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Heart
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Benedetto, U.1
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18
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84872813993
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Endovascular treatment for type B dissection in Marfan syndrome: Is it worthwhile?
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Pacini D, Parolari A, Berretta P, et al. Endovascular treatment for type B dissection in Marfan syndrome: is it worthwhile? Ann Thorac Surg 2013;95:737-49.
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Ann Thorac Surg
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Pacini, D.1
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19
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84863700756
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The immediate and long-term impact of pregnancy on aortic growth rate and mortality in women with Marfan syndrome
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Donnelly RT, Pinto NM, Kocolas I, et al. The immediate and long-term impact of pregnancy on aortic growth rate and mortality in women with Marfan syndrome. J Am Coll Cardiol 2012;60:224-9.
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J Am Coll Cardiol
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Donnelly, R.T.1
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Kocolas, I.3
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20
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84885631183
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Circulating transforming growth factor-beta as a prognostic biomarker in Marfan syndrome
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Franken R, den Hartog AW, de Waard V, et al. Circulating transforming growth factor-beta as a prognostic biomarker in Marfan syndrome. Int J Cardiol 2013;168:2441-6.
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Int J Cardiol
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Franken, R.1
Den Hartog, A.W.2
De Waard, V.3
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