Dangerous liaison: Successful percutaneous edge-to-edge mitral valve repair in patients with end-stage systolic heart failure can cause left ventricular thrombus formation

EuroIntervention

Volumn 10, Issue 2, 2014, Pages 253-259

  Orban, Martin ^a,b,c   Braun, Daniel ^a,b,c   Sonne, Carolin ^b,c   Orban, Mathias ^a,b,c   Thaler, Raffael ^a,b,c   Grebmer, Christian ^b,c   Lesevic, Hasema ^b,c   Schömig, Albert ^b,c   Mehilli, Julinda ^a,b,c   Massberg, Steffen ^a,b,c   Hausleiter, Jörg ^a,b,c  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^c DZHK GERMAN CENTRE FOR CARDIOVASCULAR RESEARCH   (Germany)

Author keywords

End stage systolic heart failure; Left ventricular thrombus; MitraClip; Mitral regurgitation; Percutaneous edge to edge mitral valve repair

Indexed keywords

ACETYLSALICYLIC ACID; ALDOSTERONE ANTAGONIST; ANGIOTENSIN RECEPTOR; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CATECHOLAMINE; CLOPIDOGREL; DIPEPTIDYL CARBOXYPEPTIDASE; HEPARIN; LOOP DIURETIC AGENT; PHENPROCOUMON; THIENOPYRIDINE DERIVATIVE;

AGED; ANGIOCARDIOGRAPHY; ANTICOAGULANT THERAPY; ARTICLE; CONTROLLED STUDY; DRUG ELUTING STENT; FEMALE; FOLLOW UP; HEART LEFT VENTRICLE; HEART LEFT VENTRICLE EJECTION FRACTION; HIGH RISK PATIENT; HOSPITALIZATION; HUMAN; IMPLANTABLE CLIP; INTRACARDIAC THROMBOSIS; LOADING DRUG DOSE; MAJOR CLINICAL STUDY; MALE; MITRAL VALVE REGURGITATION; MITRAL VALVE REPAIR; MORBIDITY; MORTALITY; PERCUTANEOUS CORONARY INTERVENTION; PERCUTANEOUS EDGE TO EDGE MITRAL VALVE REPAIR; PERCUTANEOUS TRANSLUMINAL ANGIOPLASTY; PLATELET REACTIVITY; RETROSPECTIVE STUDY; SYSTOLIC HEART FAILURE; TRANSTHORACIC ECHOCARDIOGRAPHY; CASE REPORT; COMPLICATION; DOPPLER ECHOCARDIOGRAPHY; ECHOGRAPHY; HEART FAILURE, SYSTOLIC; HEART LEFT VENTRICLE FUNCTION; HEART STROKE VOLUME; HEART SURGERY; MIDDLE AGED; MITRAL VALVE INSUFFICIENCY; PATHOPHYSIOLOGY; RISK FACTOR; SEVERITY OF ILLNESS INDEX; THROMBOSIS; TRANSESOPHAGEAL ECHOCARDIOGRAPHY; TREATMENT OUTCOME;

AGED; CARDIAC SURGICAL PROCEDURES; ECHOCARDIOGRAPHY, DOPPLER, COLOR; ECHOCARDIOGRAPHY, TRANSESOPHAGEAL; FEMALE; HEART FAILURE, SYSTOLIC; HUMANS; MALE; MIDDLE AGED; MITRAL VALVE INSUFFICIENCY; RETROSPECTIVE STUDIES; RISK FACTORS; SEVERITY OF ILLNESS INDEX; STROKE VOLUME; THROMBOSIS; TREATMENT OUTCOME; VENTRICULAR FUNCTION, LEFT;

EID: 84905439524     PISSN: 1774024X     EISSN: 19696213     Source Type: Journal    
DOI: 10.4244/EIJV10I2A41     Document Type: Article

References (20)

1. Feldman T, Kar S, Rinaldi M, Fail P, Hermiller J, Smalling R, Whitlow PL, Gray W, Low R, Herrmann HC, Lim S, Foster E, Glower D. Percutaneous mitral repair with the MitraClip system: safety and midterm durability in the initial EVEREST (Endovascular Valve Edge-to-Edge REpair Study) cohort. J Am Coll Cardiol. 2009;54:686-94.
2. Franzen O, Baldus S, Rudolph V, Meyer S, Knap M, Koschyk D, Treede H, Barmeyer A, Schofer J, Costard-Jackle A, Schluter M, Reichenspurner H, Meinertz T. Acute outcomes of MitraClip therapy for mitral regurgitation in high-surgical-risk patients: emphasis on adverse valve morphology and severe left ventricular dysfunction. Eur Heart J. 2010;31:1373-81.
3. Tamburino C, Ussia GP, Maisano F, Capodanno D, La Canna G, Scandura S, Colombo A, Giacomini A, Michev I, Mangiafico S, Cammalleri V, Barbanti M, Alfieri O. Percutaneous mitral valve repair with the MitraClip system: acute results from a real world setting. Eur Heart J. 2010;31:1382-9.
4. Feldman T, Foster E, Glower DG, Kar S, Rinaldi MJ, Fail PS, Smalling RW, Siegel R, Rose GA, Engeron E, Loghin C, Trento A, Skipper ER, Fudge T, Letsou GV, Massaro JM, Mauri L. Percutaneous repair or surgery for mitral regurgitation. N Engl J Med. 2011;364:1395-406.
5. Franzen O, van der Heyden J, Baldus S, Schluter M, Schillinger W, Butter C, Hoffmann R, Corti R, Pedrazzini G, Swaans MJ, Neuss M, Rudolph V, Surder D, Grunenfelder J, Eulenburg C, Reichenspurner H, Meinertz T, Auricchio A. MitraClip(R) therapy in patients with end-stage systolic heart failure. Eur J Heart Fail. 2011;13:569-76.
6. Whitlow PL, Feldman T, Pedersen WR, Lim DS, Kipperman R, Smalling R, Bajwa T, Herrmann HC, Lasala J, Maddux JT, Tuzcu M, Kapadia S, Trento A, Siegel RJ, Foster E, Glower D, Mauri L, Kar S. Acute and 12-month results with catheter-based mitral valve leaflet repair: the EVEREST II (Endovascular Valve Edge-to-Edge Repair) High Risk Study. J Am Coll Cardiol. 2012;59:130-9.
7. Orban M, Lesevic H, Massberg S, Hausleiter J. Left ventricular thrombus formation after successful percutaneous edge-to-edge mitral valve repair. Eur Heart J. 2013;34:942.
8. Feldman T, Wasserman HS, Herrmann HC, Gray W, Block PC, Whitlow P, St Goar F, Rodriguez L, Silvestry F, Schwartz A, Sanborn TA, Condado JA, Foster E. Percutaneous mitral valve repair using the edge-to-edge technique: six-month results of the EVEREST Phase I Clinical Trial. J Am Coll Cardiol. 2005;46:2134-40. (Pubitemid 41713603)
9. Alegria-Barrero E, Chan PH, Di Mario C, Franzen O. Tools and techniques: edge-to-edge percutaneous MitraClip(R) implantation. EuroIntervention. 2012;7:1476-8.
10. Zoghbi WA, Enriquez-Sarano M, Foster E, Grayburn PA, Kraft CD, Levine RA, Nihoyannopoulos P, Otto CM, Quinones MA, Rakowski H, Stewart WJ, Waggoner A, Weissman NJ. Recommendations for evaluation of the severity of native valvular regurgitation with two-dimensional and Doppler echocardiography. J Am Soc Echocardiogr. 2003;16:777-802. (Pubitemid 37391035)
11. Foster E, Wasserman HS, Gray W, Homma S, Di Tullio MR, Rodriguez L, Stewart WJ, Whitlow P, Block P, Martin R, Merlino J, Herrmann HC, Wiegers SE, Silvestry FE, Hamilton A, Zunamon A, Kraybill K, Gerber IL, Weeks SG, Zhang Y, Feldman T. Quantitative assessment of severity of mitral regurgitation by serial echocardiography in a multicenter clinical trial of percutaneous mitral valve repair. Am J Cardiol. 2007;100:1577-83. (Pubitemid 350050867)
12. Braun D, Orban M, Michalk F, Barthel P, Hoppe K, Sonne C, Lesevic H, Pache J, Mehilli J, Kastrati A, Hausleiter J, Massberg S. Three-dimensional transoesophageal echocardiography for the assessment of clip attachment to the leaflets in percutaneous edge-to-edge repair of the mitral valve. EuroIntervention. 2013;8:1379-87.
13. Bonello L, Tantry US, Marcucci R, Blindt R, Angiolillo DJ, Becker R, Bhatt DL, Cattaneo M, Collet JP, Cuisset T, Gachet C, Montalescot G, Jennings LK, Kereiakes D, Sibbing D, Trenk D, Van Werkum JW, Paganelli F, Price MJ, Waksman R, Gurbel PA. Consensus and future directions on the definition of high on-treatment platelet reactivity to adenosine diphosphate. J Am Coll Cardiol. 2010;56:919-33.
14. Auricchio A, Schillinger W, Meyer S, Maisano F, Hoffmann R, Ussia GP, Pedrazzini GB, van der Heyden J, Fratini S, Klersy C, Komtebedde J, Franzen O; PERMIT-CARE Investigators. Correction of mitral regurgitation in nonresponders to cardiac resynchronization therapy by MitraClip improves symptoms and promotes reverse remodeling. J Am Coll Cardiol. 2011;58:2183-9.
15. Rudolph V, Knap M, Franzen O, Schluter M, de Vries T, Conradi L, Schirmer J, Treede H, Wegscheider K, Costard-Jackle A, Meinertz T, Reichenspurner H, Baldus S. Echocardiographic and clinical outcomes of MitraClip therapy in patients not amenable to surgery. J Am Coll Cardiol. 2011;58:2190-5.
16. Baldus S, Schillinger W, Franzen O, Bekeredjian R, Sievert H, Schofer J, Kuck KH, Konorza T, Möllmann H, Hehrlein C, Ouarrak T, Senges J, Meinertz T; German Transcatheter Mitral Valve Interventions (TRAMI) investigators. MitraClip therapy in daily clinical practice: initial results from the German transcatheter mitral valve interventions (TRAMI) registry. Eur J Heart Fail. 2012;1:1050-5.
17. Schillinger W, Hunlich M, Baldus S, Ouarrak T, Boekstegers P, Hink U, Butter C, Bekeredjian R, Plicht B, Sievert H, Schofer J, Senges J, Meinertz T, Hasenfuss G. Acute outcomes after MitraClip(R) therapy in highly aged patients: results from the German TRAnscatheter Mitral valve Interventions (TRAMI) Registry. EuroIntervention. 2013;9:84-90.
18. Blondheim DS, Jacobs LE, Kotler MN, Costacurta GA, Parry WR. Dilated cardiomyopathy with mitral regurgitation: decreased survival despite a low frequency of left ventricular thrombus. Am Heart J. 1991;122:763-71.
19. Kalaria VG, Passannante MR, Shah T, Modi K, Weisse AB. Effect of mitral regurgitation on left ventricular thrombus formation in dilated cardiomyopathy. Am Heart J. 1998;135:215-20. (Pubitemid 28139159)
20. Ozdemir N, Kaymaz C, Daglar E, Karakaya O, Akcay M, Ozkan M. Severe mitral regurgitation may prevent mural thrombus formation within the left ventricle with systolic dysfunction. Jpn Heart J. 2002;43:495-503.