Mortality after Parental Death in Childhood: A Nationwide Cohort Study from Three Nordic Countries

PLoS Medicine

Volumn 11, Issue 7, 2014, Pages

  Li, Jiong ^a   Vestergaard, Mogens ^a   Cnattingius, Sven ^b   Gissler, Mika ^c   Bech, Bodil Hammer ^a   Obel, Carsten ^a   Olsen, Jørn ^a,d  

^a AARHUS UNIVERSITY   (Denmark)

^b KAROLINSKA INSTITUTE   (Sweden)

^c NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACCIDENTAL DEATH; ADULT; APGAR SCORE; ARTICLE; BEREAVEMENT; CAUSE OF DEATH; CONFOUNDING VARIABLE; DISEASE ASSOCIATION; FEMALE; FOLLOW UP; GENDER; GEOGRAPHIC DISTRIBUTION; HIGH RISK BEHAVIOR; HUMAN; MALE; MORTALITY; OUTCOME ASSESSMENT; PARENTAL DEPRIVATION; RISK ASSESSMENT; SUICIDE; WELLBEING; ADOLESCENT; CHILD; CHILDHOOD MORTALITY; COHORT ANALYSIS; DENMARK; EPIDEMIOLOGY; FINLAND; INFANT; INFANT MORTALITY; LIFE EVENT; PRESCHOOL CHILD; RISK FACTOR; STATISTICS AND NUMERICAL DATA; SWEDEN; TIME;

ADOLESCENT; BEREAVEMENT; CAUSE OF DEATH; CHILD; CHILD MORTALITY; CHILD, PRESCHOOL; COHORT STUDIES; DENMARK; FEMALE; FINLAND; HUMANS; INFANT; INFANT MORTALITY; LIFE CHANGE EVENTS; MALE; PARENTAL DEATH; RISK FACTORS; SWEDEN; TIME FACTORS;

EID: 84905389116     PISSN: 15491277     EISSN: 15491676     Source Type: Journal    
DOI: 10.1371/journal.pmed.1001679     Document Type: Article

References (51)

1. Stroebe MS, Hansson RO, Schut H, Stroebe W (2008) Handbook of bereavement research and practice: advances in theory and intervention. Washington (D.C.): American Psychological Association.
2. Christakis NA, Allison PD, (2006) Mortality after the hospitalization of a spouse. New Engl J Med 354: 719-730.
3. Stroebe M, Schut H, Stroebe W, (2007) Health outcomes of bereavement. Lancet 370: 1960-1973.
4. Levav I, Friedlander Y, Kark JD, Peritz E, (1988) An epidemiologic study of mortality among bereaved parents. N Engl J Med 319: 457-461.
5. Li J, Precht DH, Mortensen PB, Olsen J, (2003) Mortality in parents after death of a child in Denmark: a nationwide follow-up study. Lancet 361: 363-367.
6. Campbell CD, Lee JZ, (2009) Long-term mortality consequences of childhood family context in Liaoning, China, 1749-1909. Soc Sci Med 68: 1641-1648.
7. Ronsmans C, Chowdhury ME, Dasgupta SK, Ahmed A, Koblinsky M, (2005) Effect of parent's death on child survival in rural Bangladesh: a cohort study. Lancet 375: 2024-2031.
8. Sear R, Steele F, McGregor IA, Mace R, (2002) The effects of kin on child mortality in rural Gambia. Demography 39: 43-63.
9. Pavard S, Gagnon A, Desjardins B, Heyer E, (2005) Mother's death and child survival: the case of early Quebec. J Biosoc Sci 37: 209-227.
10. Willfuhr KP, (2009) Short- and long-term consequences of early parental loss in the historical population of the Krummhorn (18th and 19th century). Am J Hum Biol 21: 488-500.
11. US Bureau of the Census (1990) Statistical abstracts of the US 1990. Washington (D.C.): US Government Printing Office.
12. Bateson P, Barker D, Clutton-Brock T, Deb D, D'Udine B, et al. (2004) Developmental plasticity and human health. Nature 430: 419-421.
13. Gluckman PD, Hanson MA, Cooper C, Thornburg KL, (2008) Effect of in utero and early-life conditions on adult health and disease. New Engl J Med 359: 61-73.
14. Qin P, Agerbo E, Mortensen PB, (2002) Suicide risk in relation to family history of completed suicide and psychiatric disorders: a nested case-control study based on longitudinal registers. Lancet 360: 1126-1130.
15. Wilcox HC, Kuramoto SJ, Lichtenstein P, Langstrom N, Brent DA, et al. (2010) Psychiatric morbidity, violent crime, and suicide among children and adolescents exposed to parental death. J Am Acad Child Adolesc Psychiatry 49: 514-523.
16. Marenberg ME, Risch N, Berkman LF, Floderus B, de Faire U, (1994) Genetic susceptibility to death from coronary heart disease in a study of twins. New Engl J Med 330: 1041-1046.
17. Wellcome Trust Case Caontrol Consortium (2007) Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 447: 661-678.
18. McGirr A, Alda M, Seguin M, Cabot S, Lesage A, et al. (2009) Familial aggregation of suicide explained by cluster B traits: a three-group family study of suicide controlling for major depressive disorder. Am J Psychiatry 166: 1124-1134.
19. Luecken LJ (2008) Long-term consequences of parental death in childhood: psychological and physiological manifestations. Stroebe MS, Hansson RO, Schut H, Stroebe W, editors. Handbook of bereavement research and practice: advances in theory and intervention. Washington (D.C.): American Psychological Association. pp. 397-416.
20. Melhem NM, Porta G, Shamseddeen W, Walker Payne M, Brent DA, (2011) Grief in children and adolescents bereaved by sudden parental death. Arch Gen Psychiatry 68: 911-919.
21. Mackenbach JP, Stirbu I, Roskam AJ, Schaap MM, Menvielle G, et al. (2008) Socioeconomic inequalities in health in 22 European Countries. New Engl J Med 358: 2468-2481.
22. Mackenbach JP, Kunst AE, Cavelaars AnE, Groenhof F, Geurts JJ, (1997) Socioeconomic inequalities in morbidity and mortality in western Europe. Lancet 349: 1655-1659.
23. Lau C, Ambalavanan N, Chakraborty H, Wingate MS, Carlo WA, (2013) Extremely low birth weight and infant mortality rates in the United States. Pediatrics 131: 855-860.
24. Glinianaia S, Ghosh R, Rankin J, Pearce M, Parker L, et al. (2013) No improvement in socioeconomic inequalities in birthweight and preterm birth over four decades: a population-based cohort study. BMC Public Health 13: 345.
25. Callaghan W, MacDorman M, Rasmussen S, Qin C, Lackritz EM, (2006) The contribution of preterm birth to infant mortality rates in the United States. Pediatrics 118: 1566-1573.
26. Li J, Vestergaard M, Obel C, Cnattingus S, Gissler M, et al. (2010) Cohort profile: the Nordic perinatal bereavement cohort. Int J Epidemiol 40: 1161-1167.
27. Frank L, (2000) Epidemiology. When an entire country is a cohort. Science 287: 2398-2399.
28. Office for National Statistics (2005) Mortality statistics: childhood, infant and perinatal, England and Wales. London: ONS.
29. UNICEF (2011) The state of the world's children 2011: adolescence- an age of opportunity. Available: http://www.unicef.org/publications/files/SOWC_2011_Main_Report_EN_02242011.pdf. Accessed on 5 June 2014).
30. Andersen PK, Borgan Ø, Gill RD, Keiding N (1995) Statistical models based on counting processes. Berlin: Springer.
31. Rostila M, Saarela J, (2011) Time doesn't heal all wounds: mortality following the death of a parent. J Marriage Fam 73: 236-249.
32. East L, Jackson D, O'Brien L, (2006) Father absence and adolescent development: a review of the literature. Journal of Child Health Care 10: 283-295.
33. McLanahan S, Tach L, Schneider D, (2013) The causal effects of father absence. Annu Rev Sociol 399: 399-427, 399-427, 399-427.
34. Richter L, Morrell R. (2006) Baba: men and fatherhood in South Africa. Cape Town: HSRC Press.
35. Dietz LJ, Stoyak S, Melhem N, Porta G, Matthews KA, et al. (2013) Cortisol response to social stress in parentally bereaved youth. Biol Psychiatry 73: 379-387.
36. Tyrka AR, Wier L, Price LH, Ross N, Anderson GM, et al. (2008) Childhood parental loss and adult hypothalamic-pituitary-adrenal function. Biol Psychiatry 63: 1147-1154.
37. Alciati A, Gesuele F, Casazza G, Foschi D, (2013) The relationship between childhood parental loss and metabolic syndrome in obese subjects. Stress Health 29: 5-13.
38. Giovanoli S, Engler H, Engler A, Richetto J, Voget M, et al. (2013) Stress in puberty unmasks latent neuropathological consequences of prenatal immune activation in mice. Science 339: 1095-1099.
39. Hamdan S, Mazariegos D, Melhem NM, Porta G, Walker PM, et al. (2012) Effect of parental bereavement on health risk behaviors in youth: a 3-year follow-up. Arch Pediatr Adolesc Med 166: 216-223.
40. Felitti VJ, Anda RF, Nordenberg D, Williamson DF, Spitz AM, et al. (1998) Relationship of childhood abuse and household dysfunction to many of the leading causes of death in adults: the adverse childhood experiences (ACE) study. Am J Prev Med 14: 245-258.
41. Christ GH, Siegel K, Christ AE, (2002) Adolescent grief: "it never really hit me. until it actually happened". JAMA 288: 1269-1278.
42. Pfeffer CR, Karus D, Siegel K, Jiang H, (2000) Child survivors of parental death from cancer or suicide: depressive and behavioral outcomes. Psychooncology 9: 1-10.
43. Wolchik S, Tein JY, Sandler I, Ayers T, (2006) Stressors, quality of the child-caregiver relationship, and children's mental health problems after parental death: the mediating role of self-system beliefs. J Abnorm Child Psychol 34: 212-229.
44. Tyrka AR, Wier L, Price LH, Ross NS, Carpenter LL, (2008) Childhood parental loss and adult psychopathology: effects of loss characteristics and contextual factors. Int J Psychiatry Med 38: 329-344.
45. Bylund GT, (2013) Self-injury in teenagers who lost a parent to cancer: a nationwide, population-based, long-term follow-up. JAMA Pediatrics 167: 133-140.
46. Binder EB, Bradley RG, Liu W, Epstein MP, Deveau TC, et al. (2008) Association of FKBP5 polymorphisms and childhood abuse with risk of posttraumatic stress disorder symptoms in adults. JAMA 299: 1291-1305.
47. McGowan PO, Sasaki A, D'Alessio AC, Dymov S, Labonte B, et al. (2009) Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse. Nat Neurosci 12: 342-348.
48. Kuramoto SJ, Stuart EA, Runeson B, Lichtenstein P, Laangstrom N, et al. (2010) Maternal or paternal suicide and offspring's psychiatric and suicide-attempt hospitalization risk. Pediatrics 126: e1026-e1032.
49. Blank NM, Werner-Lin A, (2011) Growing up with grief: revisiting the death of a parent over the life course. Omega (Westport) 63: 271-290.
50. Pedersen CB, Gotzsche H, Moller JO, Mortensen PB, (2006) The Danish civil registration system. a cohort of eight million persons. Dan Med Bull 53: 441-449.
51. Rothman KJ, Greenland S, Lash TL (2008) Modern epidemiology. Philadelphia: Lippincott Williams & Wilkins.