Prospective evaluation of 2% (w/v) alcoholic chlorhexidine gluconate as an antiseptic agent for blood donor arm preparation

Asian Journal of Transfusion Science

Volumn 8, Issue 2, 2014, Pages 92-95

  Shah, Sweta ^a   Mehta, Nidhi Ajay ^a   Jadhav, Sweta Ganesh ^a  

^a KOKILABEN DHIRUBHAI AMBANI HOSPITAL   (India)

Author keywords

Bacteremia; blood donor arm; chlorhexidine gluconate

Indexed keywords

EID: 84905374684     PISSN: 09736247     EISSN: 19983565     Source Type: Journal    
DOI: 10.4103/0973-6247.137441     Document Type: Article

References (13)

1. Blajchman MA. Reducing the risk of bacterial contamination of cellular blood components. Dev Biol (Basel) 2000;102:183-93.
2. th ed. Susmit Publication, Mumbai; 2012.
3. Leslie H. Current thinking on the use of chlorhexidine as an arm preparation for donor phlebotomy. Available from: http://www.fda.gov/cber/blood/ armpreprev.htm. [Last accessed on 2011 Mar 09].
4. Hillyer CD, Josephson CD, Blajchman MA, Vostal JG, Epstein JS, Goodman JL. Bacterial contamination of blood components: Risks, strategies, and regulation: Joint ASH and AABB educational session in transfusion medicine. Hematology Am Soc Hematol Educ Program 2003;1;575-89.
5. Morel PC. The French experience in prevention of transfusion incidents due to bacterial contamination. Bacterial contamination of platelet workshop, Bethesda, MD: Food and Drug Administration, Center for Biologics Evaluation and Research; 1999. Available on http://www.fda.gov/cber/minutes/workshop-min.htm. [Last accessed on 2011 Mar 09].
6. WHO guidelines on drawing blood: Best practices in phlebotomy, WHO Library Cataloguing-in-Publication Data. World Health Organization, 2010. Available from: http://www.who.int/injection-safety/phleb-final-screen-ready. pdf. [Last accessed on 2011 Jan 09].
7. Guideline for the prevention of intravascular catheter-related bloodstream infections. 2011 Available from: http://www.cdc.gov/hicpac/pdf/ guidelines/bsi-guidelines-2011.pdf. [Last accessed on 2011 Mar 09].
8. Mullany LC, Darmstadt GL, Khatry SK, Katz J, LeClerq SC, Shrestha S, et al. Topical applications of chlorhexidine to the umbilical cord for prevention of omphalitis and neonatal mortality in southern Nepal: A community-based, cluster-randomised trial. Lancet 2006;367:910-8.
9. Wong PY, Colville VL, White V, Walker HM, Morris RA, Microbial Contamination and Infection Control Subcommittee, Australian Red Cross Blood Service. Validation and assessment of a blooddonor arm disinfectant containing chlorhexidine and alcohol. Transfusion 2004;44:1238-42.
10. Adams D, Quayum M, Worthington T, Lambert P, Elliott T. Evaluation of a 2% chlorhexidine gluconate in 70% isopropyl alcohol skin disinfectant. J Hosp Infect 2005;61:287-90.
11. Webster J, Bell-Syer SE, Foxlee R. Skin preparation with alcohol versus alcohol followed by any antiseptic for preventing bacteraemia or contamination of blood for transfusion. Cochrane Database Systematic Reviews 2013, Issue 1. Art. No.: CD007948 Available from http://onlinelibrary.wiley.com/doi/10.1002/ 14651858.CD007948.pub2/pdf. [Last accessed on 2011 Mar 09].
12. Karpanen TJ, Worthington T, Conway BR, Hilton AC, Elliott TS, Lambert PA. Penetration of chlorhexidine into human skin. Antimicrob Agents Chemother 2008;52:3633-6.
13. Adjei AA, Kuma GK, Tettey Y, Ayeh-Kumi PF, Opintan J, Apeagyei F, et al. Bacterial contamination of blood and blood components in three major blood transfusion centers, Accra, Ghana. Jpn J Infect Dis 2009;62:265-9.