Therapy with immunoglobulin in patients with acute myocarditis and cardiomyopathy: Analysis of leukocyte balance

Heart and Vessels

Volumn 29, Issue 3, 2014, Pages 336-342

  Kishimoto, Chiharu ^a   Shioji, Keisuke ^a   Hashimoto, Tetsuo ^b   Nonogi, Hiroshi ^c   Lee, Jong Dae ^d   Kato, Shigeru ^e   Hiramitsu, Shinya ^e   Morimoto, Shin Ichiro ^e  

^a KYOTO UNIVERSITY   (Japan)

^b Kyoto Takeda Hospital   (Japan)

^c NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

^d UNIVERSITY OF FUKUI   (Japan)

^e FUJITA HEALTH UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Acute myocarditis; Cytokine; Fc receptors; IVIG; Leukocyte

Indexed keywords

CYTOKINE; IMMUNOGLOBULIN; IMMUNOGLOBULIN G; INTERLEUKIN 6; SULFONATED IMMUNOGLOBULIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VENOGLOBULIN IH; AUTACOID; BIOLOGICAL MARKER; IMMUNOLOGIC FACTOR;

ACUTE MYOCARDITIS; ADULT; AGED; ARTICLE; BLOOD CELL COUNT; CARDIOMYOPATHY; CARDIOVASCULAR MORTALITY; CELL INFILTRATION; CHEMICAL ANALYSIS; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE COURSE; DRUG EFFICACY; DRUG MEGADOSE; FEMALE; HEMATOLOGICAL PARAMETERS; HEMODYNAMIC MONITORING; HUMAN; IMMUNOMODULATION; IMMUNOTHERAPY; MALE; MULTICENTER STUDY; MYOCARDITIS; PERCENTAGE OF LYMPHOCYTE; PERCENTAGE OF NEUTROPHIL; PERCENTAGE OF PERIPHERAL EOSINOPHIL; PERCENTAGE OF PERIPHERAL MONOCYTE; PERIPHERAL LEUKOCYTE BALANCE; PRIORITY JOURNAL; PROGNOSIS; RANDOMIZED CONTROLLED TRIAL; SURVIVAL RATE; UNSPECIFIED SIDE EFFECT; ACUTE DISEASE; BLOOD; CARDIOMYOPATHIES; CLINICAL TRIAL; COMPARATIVE STUDY; DRUG EFFECTS; IMMUNOLOGY; JAPAN; KAPLAN MEIER METHOD; LEUKOCYTE; LEUKOCYTE COUNT; METABOLISM; MIDDLE AGED; MORTALITY; PREDICTIVE VALUE; TIME; TREATMENT OUTCOME; VERY ELDERLY; YOUNG ADULT;

ACUTE DISEASE; ADULT; AGED; AGED, 80 AND OVER; BIOLOGICAL MARKERS; CARDIOMYOPATHIES; CYTOKINES; FEMALE; HUMANS; IMMUNOGLOBULINS, INTRAVENOUS; IMMUNOLOGIC FACTORS; INFLAMMATION MEDIATORS; JAPAN; KAPLAN-MEIER ESTIMATE; LEUKOCYTE COUNT; LEUKOCYTES; MALE; MIDDLE AGED; MYOCARDITIS; PREDICTIVE VALUE OF TESTS; TIME FACTORS; TREATMENT OUTCOME; YOUNG ADULT;

EID: 84905195961     PISSN: 09108327     EISSN: 16152573     Source Type: Journal    
DOI: 10.1007/s00380-013-0368-4     Document Type: Article

References (36)

1. Kumar K, Guirgis M, Zieroth S, Lo E, Menkis AH, Arora RC, Freed DH (2011) Influenza myocarditis and myositis: case presentation and review of the literature. Can J Cardiol 27:514-522
2. Schultheiss HP, Kühl U, Cooper LT (2011) The management of myocarditis. Eur Heart J 32:2616-2625
3. Kishimoto C (2011) Serial electrocardiographic changes in fulminant myocarditis. Circ J 75:2511
4. Mason JW, O'Connel JB, Herskowitz A, Rose NR, McManus BM, Billingham ME, Moon TE (1995) A clinical trial of immunosuppressive therapy for myocarditis. N Engl J Med 333:269-275
5. Wojnicz R, Nowalany-Kozielska E, Wojciechowska C, Glanowska G, Wilczewski P, Niklewski T, Zembala M, Polonski L, Rozek MM, Wodniecki J (2001) Randomized, placebo-controlled study for immunosuppressive treatment of inflammatory dilated cardiomyopathy. Two-year follow-up results. Circulation 104:39-45 (Pubitemid 32623287)
6. Hirano E, Shimada K, Komiyama T, Fujita M, Kishimoto C (2012) Erythromycin treatment suppresses myocardial injury in autoimmune myocarditis in rats via suppression of superoxide production. Int J Cardiol [Epub ahead of print]
7. Kishimoto C, Nimata M, Okabe TA, Shioji K (2012) Immunoglobulin treatment ameliorates myocardial injury in experimental autoimmune myocarditis associated with suppression of reactive oxygen species. Int J Cardiol [Epub ahead of print]
8. Kawai C (1999) From myocarditis to cardiomyopathy. Mechanisms of inflammation and cell death. Circulation 99:1091-1100
9. Richardson P, McKenna W, Bristow M, Maisch B, Mautner B, O'Connell J, Olsen E, Thiene G, Goodwin J, Gyarfas I, Martin I, Nordet P (1996) Report of the 1995 World Health Organization/International Society of Federation of Cardiology. Task Force on the Definition and Classification of Cardiomyopathies. Circulation 93:841-842 (Pubitemid 26074816)
10. Wolf HM, Eibl MM (1996) Immunomodulatory effect of immunoglobulins. Clin Exp Rheum 14(Suppl 15):S17-S25 (Pubitemid 26270573)
11. Rosen FS (1993) Putative mechanisms of the effect of intravenous γ-globulin. Clin Immunol Immunopathol 67:S41-S43
12. Takada H, Kishimoto C, Hiraoka Y (1995) Therapy with immunoglobulin suppresses myocarditis in a murine coxsackievirus B3 model: antiviral and anti-inflammatory effects. Circulation 92:1604-1611
13. Kishimoto C, Takamatsu N, Kawamata H, Shinohara H, Ochiai H (2000) Immunoglobulin treatment ameliorates murine myocarditis associated with reduction of neurohumoral activity and improvement of extracellular matrix change. J Am Coll Cardiol 36:1979-1984
14. Aretz HT, Billingham ME, Edwards WD, Factor SM, Fenoglio JT, Fenoglio JJ Jr, Olsen EG, Schoen FJ (1987) Myocarditis. A histopathologic definition and classification. Am J Cardiovasc Pathol 1:3-14
15. Al AA, Straatman LP, Allard MF, Ignaszewski AP (2006) Eosinophilic myocarditis. Case series and review of literature. Can J Cardiol 14:1233-1237 (Pubitemid 46138748)
16. Morimoto S, Kubo N, Hiramitsu S, Demura A, Ohtuki M, Kato S, Kato Y, Sugiura A, Miyagishima K, Mori N, Yoshida Y, Hishida H (2003) Changes in the peripheral eosinophilic count in patients with acute eosinophilic myocarditis. Heart Vessels 4:193-196 (Pubitemid 37258673)
17. Anthony RM, Kobayashi T, Wermeling F, Ravetch JV (2011) Intravenous gammaglobulin suppresses inflammation through a novel T(H)2 pathway. Nature 475:110-113
18. Drucker NA, Colan SD, Lewis AB, Beiser AS, Wessel DL, Takahashi M, Baker AL, Perez-Atayde AR, Newburger JW (1994) Gamma-globulin treatment of acute myocarditis in the pediatric population. Circulation 89:252-257 (Pubitemid 24026497)
19. McNamara DM, Rosenblum WD, Janosko KM, Trost MK, Villaneuva FS, Demetris AJ, Murali S, Feldman AM (1997) Intravenous immune globulin in the therapy of myocarditis and acute cardiomyopathy. Circulation 95:2476-2478 (Pubitemid 27233111)
20. Felix SB, Staudt A, Dörffel WV, Stangl V, Merkel K, Pohl M, Döcke WD, Morgera S, Neumayer HH, Wernecke KD, Wallukat G, Stangl K, Baumann G (2000) Hemodynamic effects of substitution and subsequent immunoglobulin substitution in dilated cardiomyopathy. J Am Coll Cardiol 35:1590-1598 (Pubitemid 30307505)
21. Bozkurt B, Villaneuva MD, Holubkov R, Tokarczyk T, Alvarez RJ Jr, MacGowan GA, Murali S, Rosenblum WD, Feldman AM, McNamara DM (1999) Intravenous immune globulin in the therapy of peripartum cardiomyopathy. J Am Coll Cardiol 34:177-180
22. Damås JK, Gullestad L, Aass H, Simonsen S, Fjeld JG, Wikeby L, Ueland T, Eiken HG, Frøland SS, Aukrust P (2001) Enhanced gene expression of chemokines and their corresponding receptors in mononuclear blood cells in chronic heart failure. Modulatory effect of intravenous immunoglobulin. J Am Coll Cardiol 38:187-193 (Pubitemid 32613849)
23. Staudt A, Schäper F, Stangl V, Plagemann A, Böhm M, Markel K, Wallukat G, Wernecke KD, Stangl K, Baumann G, Felix SB (2001) Immunological changes in dilated cardiomyopathy induced by immunoadsorption therapy and subsequent immunoglobulin substitution. Circulation 103:2681-2686 (Pubitemid 32538782)
24. Gullestad L, Aass H, Fjeld JG, Wikeby L, Andreassen AK, Ihlen H, Simonsen S, Kjekshus J, Nitter-Hauge S, Ueland T, Lien E, Frøland SS, Ankrust P (2001) Immunomodulating therapy with intravenous immunoglobulin in patients with chronic heart failure. Circulation 103:220-225 (Pubitemid 32095406)
25. Geng Y, Hansson GK, Holme E (1992) Interferon-γ and tumor necrosis factor synergize to induce nitric oxide production and inhibit mitochondrial respiration in vascular smooth muscle cells. Circ Res 71:1268-1276
26. Samuelsson A, Towers TL, Ravetch JV (2001) Anti-inflammatory activity of IVIG mediated through the inhibitory Fc receptor. Science 291:484-486 (Pubitemid 32097072)
27. Shioji K, Kishimoto C, Sasayama S (2001) Fc receptor-mediated inhibitory effect of immunoglobulin therapy upon autoimmune giant cell myocarditis. Concomitant suppression of the expression of dendritic cells. Circ Res 89:540-546 (Pubitemid 34132648)
28. Asahi A, Nishimoto T, Okazaki Y, Suzuki H, Masaoka T, Kawakami Y, Ikeda Y, Kuwana M (2008) Helicobacter pylori eradication shifts monocyte Fcγ receptor balance toward inhibitory FcγRIIB in immune thrombocytopenic purpura patients. J Clin Invest 118:2939-2949
29. Tackenberg B, Jelcic I, Baerenwaldt A, Oertel WH, Sommer N, Nimmerjahn F, Lu{combining double acute accent}nemann JD (2009) Impaired inhibitory Fcγ receptor IIB expression on B cells in chronic inflammatory demyelinating polyneuropathy. Proc Natl Acad Sci USA 106:4788-4792
30. Clatworthy MR, Willcocks L, Urban B, Langhorne J, Williams TN, Peshu N, Watkins NA, Floto RA, Smith KGC (2007) Systemic lupus erythematosus-associated defects in the inhibitory receptor FcγRIIb reduce susceptibility to malaria. Proc Natl Acad Sci USA 104:7169-7174 (Pubitemid 47186027)
31. Ravetch JV, Bolland S (2001) IgG Fc receptors. Annu Rev Immunol 19:275-290 (Pubitemid 32368037)
32. Takai T (2001) Roles of Fc receptors in autoimmunity. Nat Rev Immunol 2:580-592
33. McNamara DM, Holubkov R, Starling RC, Dec GW, Loh E, Torre-Amione G, Gass A, Karen J (2001) Controlled trial of intravenous immune globulin in recent-onset dilated cardiomyopathy. Circulation 103:2254-2259 (Pubitemid 32433714)
34. Schimke I, Müller J, Priem F, Kruse I, Schön B, Stein J, Kunze R, Wallukat G, Hetzer R (2001) Decreased oxidative stress in patients with idiopathic dilated cardiomyopathy one year after immunoglobulin adsorption. J Am Coll Cardiol 38:178-183 (Pubitemid 32613847)
35. Trucco SM, Jaeggi E, Cuneo B, Moon-Grady AJ, Silverman E, Silverman N, Hornberger LK (2011) Use of intravenous gamma globulin and corticosteroids in the treatment of maternal autoantibody-mediated cardiomyopathy. J Am Coll Cardiol 57:715-723
36. Fuse K, Kodama M, Okura Y, Ito M, Hirono S, Kato K, Hanawa H, Aizawa Y (2000) Predictors of disease course in patients with acute myocarditis. Circulation 102:2829-2835