Investigation of a PON1 gene polymorphism (rs662 polymorphism) as predictor of subclinical atherosclerosis in patients with rheumatoid arthritis

Annals of the Rheumatic Diseases

Volumn 73, Issue 9, 2014, Pages 1749-1750

  López Mejías, Raquel ^a   Genre, Fernanda ^a   Corrales, Alfonso ^a   González Juanatey, Carlos ^b   Ubilla, Begoña ^a   Llorca, Javier ^c   Miranda Filloy, José A ^b   Pina, Trinitario ^a   Blanco, Ricardo ^a   Castañeda, Santos ^d   Martín, Javier ^e   González Gay, Miguel A ^a  

^a Department of Epidemiology Genetics and Atherosclerosis Research Group on Systemic Inflammatory Diseases Rheumatology Division   (Spain)

^b Hospital Lucus Augusti   (Spain)

^c UNIVERSITY OF CANTABRIA   (Spain)

^d HOSPITAL UNIVERSITARIO DE LA PRINCESA   (Spain)

^e INSTITUTO DE PARASITOLOGÍA Y BIOMEDICINA LÓPEZ NEYRA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ARYLDIALKYLPHOSPHATASE 1;

ARTERIAL WALL THICKNESS; ATHEROSCLEROSIS; CARDIOVASCULAR RISK; CAROTID ATHEROSCLEROSIS; GENE ACTIVITY; GENE FREQUENCY; GENE LOCATION; GENETIC ASSOCIATION; GENETIC DIFFERENCE; GENETIC RISK; GENETIC VARIABILITY; HUMAN; LETTER; PON1 GENE; PREDICTION; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; RISK ASSESSMENT; SINGLE NUCLEOTIDE POLYMORPHISM; SUBCLINICAL ATHEROSCLEROSIS;

ATHEROSCLEROSIS; GENE POLYMORPHISM; RHEUMATOID ARTHRITIS;

ARTHRITIS, RHEUMATOID; ARYLDIALKYLPHOSPHATASE; ATHEROSCLEROSIS; CAROTID STENOSIS; GENE FREQUENCY; HUMANS; POLYMORPHISM, GENETIC;

EID: 84905191899     PISSN: 00034967     EISSN: 14682060     Source Type: Journal    
DOI: 10.1136/annrheumdis-2014-205543     Document Type: Letter

References (10)

1. Dessein PH, Joffe BI, Veller MG, et al. Traditional and nontraditional cardiovascular risk factors are associated with atherosclerosis in rheumatoid arthritis. J Rheumatol 2005;32:435-42. (Pubitemid 40381413)
2. González-Gay MA, González-Juanatey C. Inflammation and lipid profile in rheumatoid arthritis: bridging an apparent paradox. Ann Rheum Dis 2014;73:1281-3.
3. Charles-Schoeman C, Lee YY, Grijalva V, et al. Cholesterol efflux by high density lipoproteins is impaired in patients with active rheumatoid arthritis. Ann Rheum Dis 2012;71:1157-62.
4. Popa C, van Tits LJ, Barrera P, et al. Anti-inflammatory therapy with tumour necrosis factor alpha inhibitors improves high-density lipoprotein cholesterol antioxidative capacity in rheumatoid arthritis patients. Ann Rheum Dis 2009;68:868-72.
5. Rodríguez-Rodríguez L, González-Juanatey C, Palomino-Morales R, et al. TNFA-308 (rs1800629) polymorphism is associated with a higher risk of cardiovascular disease in patients with rheumatoid arthritis. Atherosclerosis 2011;216:125-30.
6. López-Mejías R, García-Bermúdez M, González-Juanatey C, et al. NFKB1-94ATTG ins/del polymorphism (rs28362491) is associated with cardiovascular disease in patients with rheumatoid arthritis. Atherosclerosis 2012;224:426-9.
7. Charles-Schoeman C, Lee YY, Shahbazian A, et al. Association of paraoxonase 1 gene polymorphism and enzyme activity with carotid plaque in rheumatoid arthritis. Arthritis Rheum 2013;65:2765-72.
8. Bhattacharyya T, Nicholls SJ, Topol EJ, et al. Relationship of paraoxonase 1 (PON1) gene polymorphisms and functional activity with systemic oxidative stress and cardiovascular risk. JAMA 2008;299:1265-76. (Pubitemid 351439073)
9. Corrales A, Gonzalez-Juanatey C, Peiro ME, et al. Carotid ultrasound is useful for the cardiovascular risk stratification of patients with rheumatoid arthritis: results of a population-based study. Ann Rheum Dis 2014;73:722-7.
10. Hashemi M, Moazeni-Roodi AK, Fazaeli A, et al. Lack of association between paraoxonase-1 Q192R polymorphism and rheumatoid arthritis in southeast Iran. Genet Mol Res 2010;9:333-9.