Nanoliposomes presenting on surface a cis-glycofused benzopyran compound display binding affinity and aggregation inhibition ability towards Amyloid β1-42 peptide

European Journal of Medicinal Chemistry

Volumn 85, Issue , 2014, Pages 43-50

  Airoldi, Cristina ^a   Mourtas, Spyridon ^b   Cardona, Francisco ^a,c   Zona, Cristiano ^a   Sironi, Erika ^a   D'Orazio, Giuseppe ^a   Markoutsa, Eleni ^b   Nicotra, Francesco ^a   Antimisiaris, Sophia G ^b,d   La Ferla, Barbara ^a  

^a UNIVERSITY OF MILANO BICOCCA   (Italy)

^b UNIVERSITY OF PATRAS   (Greece)

^c UNIVERSITY OF AVEIRO   (Portugal)

^d INSTITUTE OF CHEMICAL ENGINEERING SCIENCES   (Greece)

Author keywords

Alzheimer disease (AD); Amyloid (A ); Copper free click chemistry; Glycoderivatives; Liposomes; NMR interaction studies

Indexed keywords

AMYLOID BETA PROTEIN[1-42]; BENZOPYRAN DERIVATIVE; LIPOSOME; NANOLIPOSOME; UNCLASSIFIED DRUG; CHOLESTEROL; COPPER; DIPALMITOYLPHOSPHATIDYLCHOLINE; LIGAND; MACROGOL DERIVATIVE; NANOPARTICLE; PLASMA PROTEIN; AMYLOID BETA PROTEIN; AMYLOID BETA-PROTEIN (1-42); PEPTIDE FRAGMENT; PROTEIN BINDING;

ALZHEIMER DISEASE; ARTICLE; BINDING AFFINITY; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL STRUCTURE; CLICK CHEMISTRY; CONTROLLED STUDY; ELECTROSPRAY MASS SPECTROMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIPID COMPOSITION; PHYSICAL CHEMISTRY; PROTEIN AGGREGATION; PROTEIN BLOOD LEVEL; REACTION TIME; SYNTHESIS; ZETA POTENTIAL; BIOCOMPATIBILITY; COPPER FREE CLICK CHEMISTRY; FLUORESCENCE; PROTON NUCLEAR MAGNETIC RESONANCE; CHEMISTRY; DRUG EFFECTS; GLYCOSYLATION; METABOLISM; PROTEIN MULTIMERIZATION; PROTEIN SECONDARY STRUCTURE; STEREOISOMERISM; SURFACE PROPERTY;

AMYLOID BETA-PEPTIDES; BENZOPYRANS; CLICK CHEMISTRY; GLYCOSYLATION; LIGANDS; LIPOSOMES; NANOPARTICLES; PEPTIDE FRAGMENTS; PROTEIN BINDING; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, SECONDARY; STEREOISOMERISM; SURFACE PROPERTIES;

EID: 84905179397     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2014.07.085     Document Type: Article

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