-
1
-
-
0031007610
-
P100: A novel proliferation-associated nuclear protein specifically restricted to cell cycle phases S, G2, and M
-
Heidebrecht HJ, Buck F, Steinmann J, Sprenger R, Wacker HH, Parwaresch R (1997) p100: a novel proliferation-associated nuclear protein specifically restricted to cell cycle phases S, G2, and M. Blood 90(1):226-233
-
(1997)
Blood
, vol.90
, Issue.1
, pp. 226-233
-
-
Heidebrecht, H.J.1
Buck, F.2
Steinmann, J.3
Sprenger, R.4
Wacker, H.H.5
Parwaresch, R.6
-
2
-
-
0036849137
-
Chromosome-induced microtubule assembly mediated by TPX2 is required for spindle formation in HeLa cells
-
Gruss OJ, Wittmann M, Yokoyama H, Pepperkok R, Kufer T, Sillje H, Karsenti E, Mattaj IW, Vernos I (2002) Chromosome-induced microtubule assembly mediated by TPX2 is required for spindle formation in HeLa cells. Nat Cell Biol 4(11):871-879
-
(2002)
Nat Cell Biol
, vol.4
, Issue.11
, pp. 871-879
-
-
Gruss, O.J.1
Wittmann, M.2
Yokoyama, H.3
Pepperkok, R.4
Kufer, T.5
Sillje, H.6
Karsenti, E.7
Mattaj, I.W.8
Vernos, I.9
-
3
-
-
0032476724
-
Localization of the kinesin-like protein Xklp2 to spindle poles requires a leucine zipper, a microtubule-associated protein, and dynein
-
Wittmann T, Boleti H, Antony C, Karsenti E, Vernos I (1998) Localization of the kinesin-like protein Xklp2 to spindle poles requires a leucine zipper, a microtubule-associated protein, and dynein. J Cell Biol 143(3):673-685
-
(1998)
J Cell Biol
, vol.143
, Issue.3
, pp. 673-685
-
-
Wittmann, T.1
Boleti, H.2
Antony, C.3
Karsenti, E.4
Vernos, I.5
-
4
-
-
0027285087
-
Multiple kinesin-like transcripts in Xenopus oocytes
-
Vernos I, Heasman J, Wylie C (1993) Multiple kinesin-like transcripts in Xenopus oocytes. Dev Biol 157(1):232-239
-
(1993)
Dev Biol
, vol.157
, Issue.1
, pp. 232-239
-
-
Vernos, I.1
Heasman, J.2
Wylie, C.3
-
5
-
-
0030070110
-
Xklp2, a novel Xenopus centrosomal kinesin-like protein required for centrosome separation during mitosis
-
Boleti H, Karsenti E, Vernos I (1996) Xklp2, a novel Xenopus centrosomal kinesin-like protein required for centrosome separation during mitosis. Cell 84(1):49-59
-
(1996)
Cell
, vol.84
, Issue.1
, pp. 49-59
-
-
Boleti, H.1
Karsenti, E.2
Vernos, I.3
-
6
-
-
0034717818
-
TPX2, A novel Xenopus MAP involved in spindle pole organization
-
Wittmann T, Wilm M, Karsenti E, Vernos I (2000) TPX2, A novel Xenopus MAP involved in spindle pole organization. J Cell Biol 149(7):1405-1418
-
(2000)
J Cell Biol
, vol.149
, Issue.7
, pp. 1405-1418
-
-
Wittmann, T.1
Wilm, M.2
Karsenti, E.3
Vernos, I.4
-
7
-
-
0038558166
-
Importin alpha-regulated nucleation of microtubules by TPX2
-
Schatz CA, Santarella R, Hoenger A, Karsenti E, Mattaj IW, Gruss OJ, Carazo-Salas RE (2003) Importin alpha-regulated nucleation of microtubules by TPX2. EMBO J 22(9):2060-2070
-
(2003)
EMBO J
, vol.22
, Issue.9
, pp. 2060-2070
-
-
Schatz, C.A.1
Santarella, R.2
Hoenger, A.3
Karsenti, E.4
Mattaj, I.W.5
Gruss, O.J.6
Carazo-Salas, R.E.7
-
8
-
-
9444297932
-
Characterization of the TPX2 domains involved in microtubule nucleation and spindle assembly in Xenopus egg extracts
-
Brunet S, Sardon T, Zimmerman T, Wittmann T, Pepperkok R, Karsenti E, Vernos I (2004) Characterization of the TPX2 domains involved in microtubule nucleation and spindle assembly in Xenopus egg extracts. Mol Biol Cell 15(12):5318-5328
-
(2004)
Mol Biol Cell
, vol.15
, Issue.12
, pp. 5318-5328
-
-
Brunet, S.1
Sardon, T.2
Zimmerman, T.3
Wittmann, T.4
Pepperkok, R.5
Karsenti, E.6
Vernos, I.7
-
9
-
-
12244281809
-
Repp86: A human protein associated in the progression of mitosis
-
Heidebrecht HJ, Adam-Klages S, Szczepanowski M, Pollmann M, Buck F, Endl E, Kruse ML, Rudolph P, Parwaresch R (2003) Repp86: a human protein associated in the progression of mitosis. Mol Cancer Res 1(4):271-279
-
(2003)
Mol Cancer Res
, vol.1
, Issue.4
, pp. 271-279
-
-
Heidebrecht, H.J.1
Adam-Klages, S.2
Szczepanowski, M.3
Pollmann, M.4
Buck, F.5
Endl, E.6
Kruse, M.L.7
Rudolph, P.8
Parwaresch, R.9
-
10
-
-
0037100267
-
Large scale identification of human hepatocellular carcinoma-associated antigens by autoantibodies
-
Wang Y, Han KJ, Pang XW, Vaughan HA, Qu W, Dong XY, Peng JR, Zhao HT, Rui JA, Leng XS, Cebon J, Burgess AW, Chen WF (2002) Large scale identification of human hepatocellular carcinoma-associated antigens by autoantibodies. J Immunol 169(2):1102-1109
-
(2002)
J Immunol
, vol.169
, Issue.2
, pp. 1102-1109
-
-
Wang, Y.1
Han, K.J.2
Pang, X.W.3
Vaughan, H.A.4
Qu, W.5
Dong, X.Y.6
Peng, J.R.7
Zhao, H.T.8
Rui, J.A.9
Leng, X.S.10
Cebon, J.11
Burgess, A.W.12
Chen, W.F.13
-
11
-
-
0032980773
-
Assignment of human proliferation associated p100 Gene (C20orf1) to human chromosome band 20q11.2 by in situ hybridization
-
Zhang Y, Heidebrecht H, Rott A, Schlegelberger B, Parwaresch R (1999) Assignment of human proliferation associated p100 Gene (C20orf1) to human chromosome band 20q11.2 by in situ hybridization. Cytogenet Cell Genet 84(3-4):182-183
-
(1999)
Cytogenet Cell Genet
, vol.84
, Issue.3-4
, pp. 182-183
-
-
Zhang, Y.1
Heidebrecht, H.2
Rott, A.3
Schlegelberger, B.4
Parwaresch, R.5
-
12
-
-
0032846983
-
Identification of Genes (SPON2 and C20orf2) differentially expressed between cancerous and noncancerous lung cells by mRNA differential display
-
Manda R, Kohno T, Matsuno Y, Takenoshita S, Kuwano H, Yokota J (1999) Identification of Genes (SPON2 and C20orf2) differentially expressed between cancerous and noncancerous lung cells by mRNA differential display. Genomics 61(1):5-14
-
(1999)
Genomics
, vol.61
, Issue.1
, pp. 5-14
-
-
Manda, R.1
Kohno, T.2
Matsuno, Y.3
Takenoshita, S.4
Kuwano, H.5
Yokota, J.6
-
13
-
-
21044439059
-
Genes transactivated by hepatitis C virus core protein, a microarray assay
-
Liu M, Zhang SL, Cheng J, Liu Y, Wang L, Shao Q, Zhang J, Lin SM (2005) Genes transactivated by hepatitis C virus core protein, a microarray assay. World J Gastroenterol 11(22):3351-3356
-
(2005)
World J Gastroenterol
, vol.11
, Issue.22
, pp. 3351-3356
-
-
Liu, M.1
Zhang, S.L.2
Cheng, J.3
Liu, Y.4
Wang, L.5
Shao, Q.6
Zhang, J.7
Lin, S.M.8
-
14
-
-
0033461164
-
A profile of differentially expressed genes in primary colorectal cancer using suppression subtractive hybridization
-
Hufton SE, Moerkerk PT, Brandwijk R, De Bruine AP, Arends JW, Hoogenboom HR (1999) A profile of differentially expressed genes in primary colorectal cancer using suppression subtractive hybridization. FEBS Lett 463(1-2):77-82
-
(1999)
FEBS Lett
, vol.463
, Issue.1-2
, pp. 77-82
-
-
Hufton, S.E.1
Moerkerk, P.T.2
Brandwijk, R.3
De Bruine, A.P.4
Arends, J.W.5
Hoogenboom, H.R.6
-
15
-
-
82355183877
-
Identification of a TPX2-like microtubule-associated protein in Drosophila
-
Goshima G (2011) Identification of a TPX2-like microtubule-associated protein in Drosophila. PLoS ONe 6(11):e28120
-
(2011)
PLoS ONe
, vol.6
, Issue.11
-
-
Goshima, G.1
-
16
-
-
84858077472
-
The Pfam protein families database
-
(Database issue)
-
Punta M, Coggill PC, Eberhardt RY, Mistry J, Tate J, Boursnell C, Pang N, Forslund K, Ceric G, Clements J, Heger A, Holm L, Sonnhammer EL, Eddy SR, Bateman A, Finn RD (2012) The Pfam protein families database. Nucleic Acids Res 40(Database issue):D290-D301
-
(2012)
Nucleic Acids Res
, vol.40
-
-
Punta, M.1
Coggill, P.C.2
Eberhardt, R.Y.3
Mistry, J.4
Tate, J.5
Boursnell, C.6
Pang, N.7
Forslund, K.8
Ceric, G.9
Clements, J.10
Heger, A.11
Holm, L.12
Sonnhammer, E.L.13
Eddy, S.R.14
Bateman, A.15
Finn, R.D.16
-
17
-
-
0242330123
-
Structural basis of Aurora - A activation by TPX2 at the mitotic spindle
-
Bayliss R, Sardon T, Vernos I, Conti E (2003) Structural basis of Aurora-A activation by TPX2 at the mitotic spindle. Mol Cell 12(4):851-862
-
(2003)
Mol Cell
, vol.12
, Issue.4
, pp. 851-862
-
-
Bayliss, R.1
Sardon, T.2
Vernos, I.3
Conti, E.4
-
18
-
-
0035793874
-
Cell cycle. Some importin news about spindle assembly
-
Kahana JA, Cleveland DW (2001) Cell cycle. Some importin news about spindle assembly. Science 291(5509):1718-1719
-
(2001)
Science
, vol.291
, Issue.5509
, pp. 1718-1719
-
-
Kahana, J.A.1
Cleveland, D.W.2
-
19
-
-
0035312807
-
Stay tuned for some importin news about spindle assembly
-
Marshall WF, Kahana JA (2001) Stay tuned for some importin news about spindle assembly. Trends Cell Biol 11(4):148
-
(2001)
Trends Cell Biol
, vol.11
, Issue.4
, pp. 148
-
-
Marshall, W.F.1
Kahana, J.A.2
-
20
-
-
4644233153
-
The mechanism of spindle assembly: Functions of Ran and its target TPX2
-
Gruss OJ, Vernos I (2004) The mechanism of spindle assembly: functions of Ran and its target TPX2. J Cell Biol 166(7):949-955
-
(2004)
J Cell Biol
, vol.166
, Issue.7
, pp. 949-955
-
-
Gruss, O.J.1
Vernos, I.2
-
21
-
-
77952909627
-
Novel binding of the mitotic regulator TPX2 (target protein for Xenopus kinesin-like protein 2) to importin-alpha
-
Giesecke A, Stewart M (2010) Novel binding of the mitotic regulator TPX2 (target protein for Xenopus kinesin-like protein 2) to importin-alpha. J Biol Chem 285(23):17628-17635
-
(2010)
J Biol Chem
, vol.285
, Issue.23
, pp. 17628-17635
-
-
Giesecke, A.1
Stewart, M.2
-
22
-
-
70350575315
-
The role of Hklp2 in the stabilization and maintenance of spindle bipolarity
-
Vanneste D, Takagi M, Imamoto N, Vernos I (2009) The role of Hklp2 in the stabilization and maintenance of spindle bipolarity. Curr Biol 19(20):1712-1717
-
(2009)
Curr Biol
, vol.19
, Issue.20
, pp. 1712-1717
-
-
Vanneste, D.1
Takagi, M.2
Imamoto, N.3
Vernos, I.4
-
23
-
-
0348013019
-
Ran modulates spindle assembly by regulating a subset of TPX2 and Kid activities including Aurora A activation
-
Trieselmann N, Armstrong S, Rauw J, Wilde A (2003) Ran modulates spindle assembly by regulating a subset of TPX2 and Kid activities including Aurora A activation. J Cell Sci 116(Pt 23):4791-4798
-
(2003)
J Cell Sci
, vol.116
, Issue.PART 23
, pp. 4791-4798
-
-
Trieselmann, N.1
Armstrong, S.2
Rauw, J.3
Wilde, A.4
-
24
-
-
33749424376
-
Ran at a glance
-
Joseph J (2006) Ran at a glance. J Cell Sci 119(Pt 17):3481-3484
-
(2006)
J Cell Sci
, vol.119
, Issue.PART 17
, pp. 3481-3484
-
-
Joseph, J.1
-
25
-
-
0028222104
-
RanGAP1 induces GTPase activity of nuclear Rasrelated Ran
-
Bischoff FR, Klebe C, Kretschmer J, Wittinghofer A, Ponstingl H (1994) RanGAP1 induces GTPase activity of nuclear Rasrelated Ran. Proc Natl Acad Sci USA 91(7):2587-2591
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, Issue.7
, pp. 2587-2591
-
-
Bischoff, F.R.1
Klebe, C.2
Kretschmer, J.3
Wittinghofer, A.4
Ponstingl, H.5
-
26
-
-
0033522118
-
Structure of a Ran-binding domain complexed with Ran bound to a GTP analogue: Implications for nuclear transport
-
Vetter IR, Nowak C, Nishimoto T, Kuhlmann J, Wittinghofer A (1999) Structure of a Ran-binding domain complexed with Ran bound to a GTP analogue: implications for nuclear transport. Nature 398(6722):39-46
-
(1999)
Nature
, vol.398
, Issue.6722
, pp. 39-46
-
-
Vetter, I.R.1
Nowak, C.2
Nishimoto, T.3
Kuhlmann, J.4
Wittinghofer, A.5
-
27
-
-
0026419320
-
Catalysis of guanine nucleotide exchange on Ran by the mitotic regulator RCC1
-
Bischoff FR, Ponstingl H (1991) Catalysis of guanine nucleotide exchange on Ran by the mitotic regulator RCC1. Nature 354(6348):80-82
-
(1991)
Nature
, vol.354
, Issue.6348
, pp. 80-82
-
-
Bischoff, F.R.1
Ponstingl, H.2
-
28
-
-
0028801195
-
The kinetic mechanism of Ran-nucleotide exchange catalyzed by RCC1
-
Klebe C, Prinz H, Wittinghofer A, Goody RS (1995) The kinetic mechanism of Ran-nucleotide exchange catalyzed by RCC1. Biochemistry 34(39):12543-12552
-
(1995)
Biochemistry
, vol.34
, Issue.39
, pp. 12543-12552
-
-
Klebe, C.1
Prinz, H.2
Wittinghofer, A.3
Goody, R.S.4
-
29
-
-
0027413917
-
RCC1 in the cell cycle: The regulator of chromosome condensation takes on new roles
-
Dasso M (1993) RCC1 in the cell cycle: the regulator of chromosome condensation takes on new roles. Trends Biochem Sci 18(3):96-101
-
(1993)
Trends Biochem Sci
, vol.18
, Issue.3
, pp. 96-101
-
-
Dasso, M.1
-
30
-
-
0037416225
-
Characterization of Ran-driven cargo transport and the RanGTPase system by kinetic measurements and computer simulation
-
Gorlich D, Seewald MJ, Ribbeck K (2003) Characterization of Ran-driven cargo transport and the RanGTPase system by kinetic measurements and computer simulation. EMBO J 22(5):1088-1100
-
(2003)
EMBO J
, vol.22
, Issue.5
, pp. 1088-1100
-
-
Gorlich, D.1
Seewald, M.J.2
Ribbeck, K.3
-
31
-
-
0033279841
-
Transport between the cell nucleus and the cytoplasm
-
Gorlich D, Kutay U (1999) Transport between the cell nucleus and the cytoplasm. Annu Rev Cell Dev Biol 15:607-660
-
(1999)
Annu Rev Cell Dev Biol
, vol.15
, pp. 607-660
-
-
Gorlich, D.1
Kutay, U.2
-
32
-
-
0031707505
-
Nucleocytoplasmic transport: The soluble phase
-
Mattaj IW, Englmeier L (1998) Nucleocytoplasmic transport: the soluble phase. Annu Rev Biochem 67:265-306
-
(1998)
Annu Rev Biochem
, vol.67
, pp. 265-306
-
-
Mattaj, I.W.1
Englmeier, L.2
-
33
-
-
84857047339
-
PhosphoSitePlus: A comprehensive resource for investigating the structure and function of experimentally determined post-translational modifications in man and mouse
-
(Database issue)
-
Hornbeck PV, Kornhauser JM, Tkachev S, Zhang B, Skrzypek E, Murray B, Latham V, Sullivan M (2012) PhosphoSitePlus: a comprehensive resource for investigating the structure and function of experimentally determined post-translational modifications in man and mouse. Nucleic Acids Res 40(Database issue):D261-D270
-
(2012)
Nucleic Acids Res
, vol.40
-
-
Hornbeck, P.V.1
Kornhauser, J.M.2
Tkachev, S.3
Zhang, B.4
Skrzypek, E.5
Murray, B.6
Latham, V.7
Sullivan, M.8
-
34
-
-
0035445281
-
Ran GTPase: A master regulator of nuclear structure and function during the eukaryotic cell division cycle?
-
Clarke PR, Zhang C (2001) Ran GTPase: a master regulator of nuclear structure and function during the eukaryotic cell division cycle? Trends Cell Biol 11(9):366-371
-
(2001)
Trends Cell Biol
, vol.11
, Issue.9
, pp. 366-371
-
-
Clarke, P.R.1
Zhang, C.2
-
35
-
-
0037162398
-
The Ran GTPase: Theme and variations
-
Dasso M (2002) The Ran GTPase: theme and variations. Curr Biol 12(14):R502-R508
-
(2002)
Curr Biol
, vol.12
, Issue.14
-
-
Dasso, M.1
-
36
-
-
4143086570
-
Mitotic functions of the Ran GTPase network: The importance of being in the right place at the right time
-
Di Fiore B, Ciciarello M, Lavia P (2004) Mitotic functions of the Ran GTPase network: the importance of being in the right place at the right time. Cell Cycle 3(3):305-313
-
(2004)
Cell Cycle
, vol.3
, Issue.3
, pp. 305-313
-
-
Di Fiore, B.1
Ciciarello, M.2
Lavia, P.3
-
37
-
-
0036306726
-
The Ran GTPase as a marker of chromosome position in spindle formation and nuclear envelope assembly
-
Hetzer M, Gruss OJ, Mattaj IW (2002) The Ran GTPase as a marker of chromosome position in spindle formation and nuclear envelope assembly. Nat Cell Biol 4(7):e177-e184
-
(2002)
Nat Cell Biol
, vol.4
, Issue.7
-
-
Hetzer, M.1
Gruss, O.J.2
Mattaj, I.W.3
-
38
-
-
0038699131
-
The small GTPase Ran: Interpreting the signs
-
Quimby BB, Dasso M (2003) The small GTPase Ran: interpreting the signs. Curr Opin Cell Biol 15(3):338-344
-
(2003)
Curr Opin Cell Biol
, vol.15
, Issue.3
, pp. 338-344
-
-
Quimby, B.B.1
Dasso, M.2
-
39
-
-
0037459085
-
Regulating access to the genome: Nucleocytoplasmic transport throughout the cell cycle
-
Weis K (2003) Regulating access to the genome: nucleocytoplasmic transport throughout the cell cycle. Cell 112(4):441-451
-
(2003)
Cell
, vol.112
, Issue.4
, pp. 441-451
-
-
Weis, K.1
-
40
-
-
0033536178
-
Generation of GTP-bound Ran by RCC1 is required for chromatin-induced mitotic spindle formation
-
Carazo-Salas RE, Guarguaglini G, Gruss OJ, Segref A, Karsenti E, Mattaj IW (1999) Generation of GTP-bound Ran by RCC1 is required for chromatin-induced mitotic spindle formation. Nature 400(6740):178-181
-
(1999)
Nature
, vol.400
, Issue.6740
, pp. 178-181
-
-
Carazo-Salas, R.E.1
Guarguaglini, G.2
Gruss, O.J.3
Segref, A.4
Karsenti, E.5
Mattaj, I.W.6
-
41
-
-
17744380396
-
Ran induces spindle assembly by reversing the inhibitory effect of importin alpha on TPX2 activity
-
Gruss OJ, Carazo-Salas RE, Schatz CA, Guarguaglini G, Kast J, Wilm M, Le Bot N, Vernos I, Karsenti E, Mattaj IW (2001) Ran induces spindle assembly by reversing the inhibitory effect of importin alpha on TPX2 activity. Cell 104(1):83-93
-
(2001)
Cell
, vol.104
, Issue.1
, pp. 83-93
-
-
Gruss, O.J.1
Carazo-Salas, R.E.2
Schatz, C.A.3
Guarguaglini, G.4
Kast, J.5
Wilm, M.6
Le Bot, N.7
Vernos, I.8
Karsenti, E.9
Mattaj, I.W.10
-
42
-
-
0037192461
-
Visualization of a Ran-GTP gradient in interphase and mitotic Xenopus egg extracts
-
Kalab P, Weis K, Heald R (2002) Visualization of a Ran-GTP gradient in interphase and mitotic Xenopus egg extracts. Science 295(5564):2452-2456
-
(2002)
Science
, vol.295
, Issue.5564
, pp. 2452-2456
-
-
Kalab, P.1
Weis, K.2
Heald, R.3
-
43
-
-
1642304137
-
Phosphorylation of RCC1 in mitosis is essential for producing a high RanGTP concentration on chromosomes and for spindle assembly in mammalian cells
-
Li HY, Zheng Y (2004) Phosphorylation of RCC1 in mitosis is essential for producing a high RanGTP concentration on chromosomes and for spindle assembly in mammalian cells. Genes Dev 18(5):512-527
-
(2004)
Genes Dev
, vol.18
, Issue.5
, pp. 512-527
-
-
Li, H.Y.1
Zheng, Y.2
-
44
-
-
0035846901
-
Importin beta is a mitotic target of the small GTPase Ran in spindle assembly
-
Nachury MV, Maresca TJ, Salmon WC, Waterman-Storer CM, Heald R, Weis K (2001) Importin beta is a mitotic target of the small GTPase Ran in spindle assembly. Cell 104(1):95-106
-
(2001)
Cell
, vol.104
, Issue.1
, pp. 95-106
-
-
Nachury, M.V.1
Maresca, T.J.2
Salmon, W.C.3
Waterman-Storer, C.M.4
Heald, R.5
Weis, K.6
-
45
-
-
0035951480
-
Role of importin-beta in coupling Ran to downstream targets in microtubule assembly
-
Wiese C, Wilde A, Moore MS, Adam SA, Merdes A, Zheng Y (2001) Role of importin-beta in coupling Ran to downstream targets in microtubule assembly. Science 291(5504):653-656
-
(2001)
Science
, vol.291
, Issue.5504
, pp. 653-656
-
-
Wiese, C.1
Wilde, A.2
Moore, M.S.3
Adam, S.A.4
Merdes, A.5
Zheng, Y.6
-
46
-
-
3242657509
-
The chromosomal passenger complex is required for chromatin-induced microtubule stabilization and spindle assembly
-
Sampath SC, Ohi R, Leismann O, Salic A, Pozniakovski A, Funabiki H (2004) The chromosomal passenger complex is required for chromatin-induced microtubule stabilization and spindle assembly. Cell 118(2):187-202
-
(2004)
Cell
, vol.118
, Issue.2
, pp. 187-202
-
-
Sampath, S.C.1
Ohi, R.2
Leismann, O.3
Salic, A.4
Pozniakovski, A.5
Funabiki, H.6
-
47
-
-
67650951148
-
Spindle assembly in the absence of a RanGTP gradient requires localized CPC activity
-
Maresca TJ, Groen AC, Gatlin JC, Ohi R, Mitchison TJ, Salmon ED (2009) Spindle assembly in the absence of a RanGTP gradient requires localized CPC activity. Curr Biol 19(14):1210-1215
-
(2009)
Curr Biol
, vol.19
, Issue.14
, pp. 1210-1215
-
-
Maresca, T.J.1
Groen, A.C.2
Gatlin, J.C.3
Ohi, R.4
Mitchison, T.J.5
Salmon, E.D.6
-
48
-
-
0035090344
-
Ran-GTP coordinates regulation of microtubule nucleation and dynamics during mitotic-spindle assembly
-
Carazo-Salas RE, Gruss OJ, Mattaj IW, Karsenti E (2001) Ran-GTP coordinates regulation of microtubule nucleation and dynamics during mitotic-spindle assembly. Nat Cell Biol 3(3):228-234
-
(2001)
Nat Cell Biol
, vol.3
, Issue.3
, pp. 228-234
-
-
Carazo-Salas, R.E.1
Gruss, O.J.2
Mattaj, I.W.3
Karsenti, E.4
-
49
-
-
84874077607
-
Branching microtubule nucleation in Xenopus egg extracts mediated by augmin and TPX2
-
Petry S, Groen AC, Ishihara K, Mitchison TJ, Vale RD (2013) Branching microtubule nucleation in Xenopus egg extracts mediated by augmin and TPX2. Cell 152(4):768-777
-
(2013)
Cell
, vol.152
, Issue.4
, pp. 768-777
-
-
Petry, S.1
Groen, A.C.2
Ishihara, K.3
Mitchison, T.J.4
Vale, R.D.5
-
50
-
-
43149110086
-
Self-organization of anastral spindles by synergy of dynamic instability, autocatalytic microtubule production, and a spatial signaling gradient
-
Clausen T, Ribbeck K (2007) Self-organization of anastral spindles by synergy of dynamic instability, autocatalytic microtubule production, and a spatial signaling gradient. PLoS ONe 2(2):e244
-
(2007)
PLoS ONe
, vol.2
, Issue.2
-
-
Clausen, T.1
Ribbeck, K.2
-
51
-
-
34548229419
-
Regulation of repp86 stability by human Siah2
-
Szczepanowski M, Adam-Klages S, Kruse ML, Pollmann M, Klapper W, Parwaresch R, Heidebrecht HJ (2007) Regulation of repp86 stability by human Siah2. Biochem Biophys Res Commun 362(2):485-490
-
(2007)
Biochem Biophys Res Commun
, vol.362
, Issue.2
, pp. 485-490
-
-
Szczepanowski, M.1
Adam-Klages, S.2
Kruse, M.L.3
Pollmann, M.4
Klapper, W.5
Parwaresch, R.6
Heidebrecht, H.J.7
-
52
-
-
33644746123
-
Molecular requirements for kinetochore-associated microtubule formation in mammalian cells
-
Tulu US, Fagerstrom C, Ferenz NP, Wadsworth P (2006) Molecular requirements for kinetochore-associated microtubule formation in mammalian cells. Curr Biol 16(5):536-541
-
(2006)
Curr Biol
, vol.16
, Issue.5
, pp. 536-541
-
-
Tulu, U.S.1
Fagerstrom, C.2
Ferenz, N.P.3
Wadsworth, P.4
-
53
-
-
32244446180
-
A functional interplay between Aurora-A, Plk1 and TPX2 at spindle poles: Plk1 controls centrosomal localization of Aurora - A and TPX2 spindle association
-
De Luca M, Lavia P, Guarguaglini G (2006) A functional interplay between Aurora-A, Plk1 and TPX2 at spindle poles: Plk1 controls centrosomal localization of Aurora-A and TPX2 spindle association. Cell Cycle 5(3):296-303
-
(2006)
Cell Cycle
, vol.5
, Issue.3
, pp. 296-303
-
-
De Luca, M.1
Lavia, P.2
Guarguaglini, G.3
-
54
-
-
18844464851
-
Htpx2 is required for normal spindle morphology and centrosome integrity during vertebrate cell division
-
Garrett S, Auer K, Compton DA, Kapoor TM (2002) Htpx2 is required for normal spindle morphology and centrosome integrity during vertebrate cell division. Curr Biol 12(23):2055-2059
-
(2002)
Curr Biol
, vol.12
, Issue.23
, pp. 2055-2059
-
-
Garrett, S.1
Auer, K.2
Compton, D.A.3
Kapoor, T.M.4
-
55
-
-
0037446847
-
A novel mechanism for activation of the protein kinase Aurora A
-
Eyers PA, Erikson E, Chen LG, Maller JL (2003) A novel mechanism for activation of the protein kinase Aurora A. Curr Biol 13(8):691-697
-
(2003)
Curr Biol
, vol.13
, Issue.8
, pp. 691-697
-
-
Eyers, P.A.1
Erikson, E.2
Chen, L.G.3
Maller, J.L.4
-
56
-
-
0037135979
-
Human TPX2 is required for targeting Aurora - A kinase to the spindle
-
Kufer TA, Sillje HH, Korner R, Gruss OJ, Meraldi P, Nigg EA (2002) Human TPX2 is required for targeting Aurora-A kinase to the spindle. J Cell Biol 158(4):617-623
-
(2002)
J Cell Biol
, vol.158
, Issue.4
, pp. 617-623
-
-
Kufer, T.A.1
Sillje, H.H.2
Korner, R.3
Gruss, O.J.4
Meraldi, P.5
Nigg, E.A.6
-
57
-
-
0037341906
-
A Ran signalling pathway mediated by the mitotic kinase Aurora A in spindle assembly
-
Tsai MY, Wiese C, Cao K, Martin O, Donovan P, Ruderman J, Prigent C, Zheng Y (2003) A Ran signalling pathway mediated by the mitotic kinase Aurora A in spindle assembly. Nat Cell Biol 5(3):242-248
-
(2003)
Nat Cell Biol
, vol.5
, Issue.3
, pp. 242-248
-
-
Tsai, M.Y.1
Wiese, C.2
Cao, K.3
Martin, O.4
Donovan, P.5
Ruderman, J.6
Prigent, C.7
Zheng, Y.8
-
58
-
-
51649095569
-
The Aurora kinase family in cell division and cancer
-
Vader G, Lens SM (2008) The Aurora kinase family in cell division and cancer. Biochim Biophys Acta 1786(1):60-72
-
(2008)
Biochim Biophys Acta
, vol.1786
, Issue.1
, pp. 60-72
-
-
Vader, G.1
Lens, S.M.2
-
59
-
-
0028938482
-
Mutations in aurora prevent centrosome separation leading to the formation of monopolar spindles
-
Glover DM, Leibowitz MH, McLean DA, Parry H (1995) Mutations in aurora prevent centrosome separation leading to the formation of monopolar spindles. Cell 81(1):95-105
-
(1995)
Cell
, vol.81
, Issue.1
, pp. 95-105
-
-
Glover, D.M.1
Leibowitz, M.H.2
McLean, D.A.3
Parry, H.4
-
60
-
-
78649511384
-
The Aurora-A/TPX2 complex: A novel oncogenic holoenzyme?
-
Asteriti IA, Rensen WM, Lindon C, Lavia P, Guarguaglini G (2010) The Aurora-A/TPX2 complex: a novel oncogenic holoenzyme? Biochim Biophys Acta 1806(2):230-239
-
(2010)
Biochim Biophys Acta
, vol.1806
, Issue.2
, pp. 230-239
-
-
Asteriti, I.A.1
Rensen, W.M.2
Lindon, C.3
Lavia, P.4
Guarguaglini, G.5
-
61
-
-
34948901399
-
Aurora-A: The maker and breaker of spindle poles
-
Barr AR, Gergely F (2007) Aurora-A: the maker and breaker of spindle poles. J Cell Sci 120(Pt 17):2987-2996
-
(2007)
J Cell Sci
, vol.120
, Issue.PART 17
, pp. 2987-2996
-
-
Barr, A.R.1
Gergely, F.2
-
62
-
-
80051962870
-
Biology of Aurora A kinase: Implications in cancer manifestation and therapy
-
Karthigeyan D, Prasad SB, Shandilya J, Agrawal S, Kundu TK (2011) Biology of Aurora A kinase: implications in cancer manifestation and therapy. Med Res Rev 31(5):757-793
-
(2011)
Med Res Rev
, vol.31
, Issue.5
, pp. 757-793
-
-
Karthigeyan, D.1
Prasad, S.B.2
Shandilya, J.3
Agrawal, S.4
Kundu, T.K.5
-
63
-
-
0141429171
-
Aurora - A and an interacting activator, the LIM protein Ajuba, are required for mitotic commitment in human cells
-
Hirota T, Kunitoku N, Sasayama T, Marumoto T, Zhang D, Nitta M, Hatakeyama K, Saya H (2003) Aurora-A and an interacting activator, the LIM protein Ajuba, are required for mitotic commitment in human cells. Cell 114(5):585-598
-
(2003)
Cell
, vol.114
, Issue.5
, pp. 585-598
-
-
Hirota, T.1
Kunitoku, N.2
Sasayama, T.3
Marumoto, T.4
Zhang, D.5
Nitta, M.6
Hatakeyama, K.7
Saya, H.8
-
64
-
-
3042734502
-
Phosphorylation of CDC25B by Aurora - A at the centrosome contributes to the G2-M transition
-
Dutertre S, Cazales M, Quaranta M, Froment C, Trabut V, Dozier C, Mirey G, Bouche JP, Theis-Febvre N, Schmitt E, Monsarrat B, Prigent C, Ducommun B (2004) Phosphorylation of CDC25B by Aurora-A at the centrosome contributes to the G2-M transition. J Cell Sci 117(Pt 12):2523-2531
-
(2004)
J Cell Sci
, vol.117
, Issue.PART 12
, pp. 2523-2531
-
-
Dutertre, S.1
Cazales, M.2
Quaranta, M.3
Froment, C.4
Trabut, V.5
Dozier, C.6
Mirey, G.7
Bouche, J.P.8
Theis-Febvre, N.9
Schmitt, E.10
Monsarrat, B.11
Prigent, C.12
Ducommun, B.13
-
65
-
-
66349112569
-
Aurora - A and hBora join the game of Polo
-
Macurek L, Lindqvist A, Medema RH (2009) Aurora-A and hBora join the game of Polo. Cancer Res 69(11):4555-4558
-
(2009)
Cancer Res
, vol.69
, Issue.11
, pp. 4555-4558
-
-
Macurek, L.1
Lindqvist, A.2
Medema, R.H.3
-
66
-
-
0030946109
-
Cell cycle-dependent expression and spindle pole localization of a novel human protein kinase, Aik, related to Aurora of Drosophila and yeast Ipl1
-
Kimura M, Kotani S, Hattori T, Sumi N, Yoshioka T, Todokoro K, Okano Y (1997) Cell cycle-dependent expression and spindle pole localization of a novel human protein kinase, Aik, related to Aurora of Drosophila and yeast Ipl1. J Biol Chem 272(21):13766-13771
-
(1997)
J Biol Chem
, vol.272
, Issue.21
, pp. 13766-13771
-
-
Kimura, M.1
Kotani, S.2
Hattori, T.3
Sumi, N.4
Yoshioka, T.5
Todokoro, K.6
Okano, Y.7
-
67
-
-
0034609753
-
The mitotic serine/threonine kinase Aurora2/AIK is regulated by phosphorylation and degradation
-
Walter AO, Seghezzi W, Korver W, Sheung J, Lees E (2000) The mitotic serine/threonine kinase Aurora2/AIK is regulated by phosphorylation and degradation. Oncogene 19(42):4906-4916
-
(2000)
Oncogene
, vol.19
, Issue.42
, pp. 4906-4916
-
-
Walter, A.O.1
Seghezzi, W.2
Korver, W.3
Sheung, J.4
Lees, E.5
-
68
-
-
0032100685
-
A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers
-
Bischoff JR, Anderson L, Zhu Y, Mossie K, Ng L, Souza B, Schryver B, Flanagan P, Clairvoyant F, Ginther C, Chan CS, Novotny M, Slamon DJ, Plowman GD (1998) A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers. EMBO J 17(11):3052-3065
-
(1998)
EMBO J
, vol.17
, Issue.11
, pp. 3052-3065
-
-
Bischoff, J.R.1
Anderson, L.2
Zhu, Y.3
Mossie, K.4
Ng, L.5
Souza, B.6
Schryver, B.7
Flanagan, P.8
Clairvoyant, F.9
Ginther, C.10
Chan, C.S.11
Novotny, M.12
Slamon, D.J.13
Plowman, G.D.14
-
69
-
-
0037157197
-
Degradation of human Aurora - A protein kinase is mediated by hCdh1
-
Taguchi S, Honda K, Sugiura K, Yamaguchi A, Furukawa K, Urano T (2002) Degradation of human Aurora-A protein kinase is mediated by hCdh1. FEBS Lett 519(1-3):59-65
-
(2002)
FEBS Lett
, vol.519
, Issue.1-3
, pp. 59-65
-
-
Taguchi, S.1
Honda, K.2
Sugiura, K.3
Yamaguchi, A.4
Furukawa, K.5
Urano, T.6
-
70
-
-
12344309497
-
Requirements for the destruction of human Aurora-A
-
Crane R, Kloepfer A, Ruderman JV (2004) Requirements for the destruction of human Aurora-A. J Cell Sci 117(Pt 25):5975-5983
-
(2004)
J Cell Sci
, vol.117
, Issue.PART 25
, pp. 5975-5983
-
-
Crane, R.1
Kloepfer, A.2
Ruderman, J.V.3
-
71
-
-
0036714512
-
Identification of a new APC/C recognition domain, the A box, which is required for the Cdh1-dependent destruction of the kinase Aurora - A during mitotic exit
-
Littlepage LE, Ruderman JV (2002) Identification of a new APC/C recognition domain, the A box, which is required for the Cdh1-dependent destruction of the kinase Aurora-A during mitotic exit. Genes Dev 16(17):2274-2285
-
(2002)
Genes Dev
, vol.16
, Issue.17
, pp. 2274-2285
-
-
Littlepage, L.E.1
Ruderman, J.V.2
-
72
-
-
27944458407
-
Anaphase-promoting complex/cyclosome controls the stability of TPX2 during mitotic exit
-
Stewart S, Fang G (2005) Anaphase-promoting complex/cyclosome controls the stability of TPX2 during mitotic exit. Mol Cell Biol 25(23):10516-10527
-
(2005)
Mol Cell Biol
, vol.25
, Issue.23
, pp. 10516-10527
-
-
Stewart, S.1
Fang, G.2
-
73
-
-
0347985493
-
Regulation of Aurora - A kinase on the mitotic spindle
-
Kufer TA, Nigg EA, Sillje HH (2003) Regulation of Aurora-A kinase on the mitotic spindle. Chromosoma 112(4):159-163
-
(2003)
Chromosoma
, vol.112
, Issue.4
, pp. 159-163
-
-
Kufer, T.A.1
Nigg, E.A.2
Sillje, H.H.3
-
74
-
-
0037180488
-
Identification of phosphorylated residues that affect the activity of the mitotic kinase Aurora-A
-
Littlepage LE, Wu H, Andresson T, Deanehan JK, Amundadottir LT, Ruderman JV (2002) Identification of phosphorylated residues that affect the activity of the mitotic kinase Aurora-A. Proc Natl Acad Sci USA 99(24):15440-15445
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, Issue.24
, pp. 15440-15445
-
-
Littlepage, L.E.1
Wu, H.2
Andresson, T.3
Deanehan, J.K.4
Amundadottir, L.T.5
Ruderman, J.V.6
-
75
-
-
2942590333
-
Activation of Aurora - A kinase by protein phosphatase inhibitor-2, a bifunctional signaling protein
-
Satinover DL, Leach CA, Stukenberg PT, Brautigan DL (2004) Activation of Aurora-A kinase by protein phosphatase inhibitor-2, a bifunctional signaling protein. Proc Natl Acad Sci USA 101(23):8625-8630
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, Issue.23
, pp. 8625-8630
-
-
Satinover, D.L.1
Leach, C.A.2
Stukenberg, P.T.3
Brautigan, D.L.4
-
76
-
-
78651075305
-
Control of Aurora - A stability through interaction with TPX2
-
Giubettini M, Asteriti IA, Scrofani J, De Luca M, Lindon C, Lavia P, Guarguaglini G (2011) Control of Aurora-A stability through interaction with TPX2. J Cell Sci 124(Pt 1):113-122
-
(2011)
J Cell Sci
, vol.124
, Issue.PART 1
, pp. 113-122
-
-
Giubettini, M.1
Asteriti, I.A.2
Scrofani, J.3
De Luca, M.4
Lindon, C.5
Lavia, P.6
Guarguaglini, G.7
-
77
-
-
84855758341
-
Plant Aurora kinases play a role in maintenance of primary meristems and control of endoreduplication
-
Petrovska B, Cenklova V, Pochylova Z, Kourova H, Doskocilova A, Plihal O, Binarova L, Binarova P (2012) Plant Aurora kinases play a role in maintenance of primary meristems and control of endoreduplication. New Phytol 193(3):590-604
-
(2012)
New Phytol
, vol.193
, Issue.3
, pp. 590-604
-
-
Petrovska, B.1
Cenklova, V.2
Pochylova, Z.3
Kourova, H.4
Doskocilova, A.5
Plihal, O.6
Binarova, L.7
Binarova, P.8
-
78
-
-
84887920643
-
Overexpressed TPX2 causes ectopic formation of microtubular arrays in the nuclei of acentrosomal plant cells
-
Petrovska Query B, Jerabkova H, Kohoutova L, Cenklova V, Pochylova Z, Gelova Z, Kocarova G, Vachova L, Kurejova M, Tomastikova E, Binarova P (2013) Overexpressed TPX2 causes ectopic formation of microtubular arrays in the nuclei of acentrosomal plant cells. J Exp Bot 64(14):4575-4587
-
(2013)
J Exp Bot
, vol.64
, Issue.14
, pp. 4575-4587
-
-
Petrovska Query, B.1
Jerabkova, H.2
Kohoutova, L.3
Cenklova, V.4
Pochylova, Z.5
Gelova, Z.6
Kocarova, G.7
Vachova, L.8
Kurejova, M.9
Tomastikova, E.10
Binarova, P.11
-
79
-
-
84861536444
-
A novel role for TPX2 as a scaffold and co-activator protein of the Chromosomal Passenger Complex
-
Iyer J, Tsai MY (2012) A novel role for TPX2 as a scaffold and co-activator protein of the Chromosomal Passenger Complex. Cell Signal 24(8):1677-1689
-
(2012)
Cell Signal
, vol.24
, Issue.8
, pp. 1677-1689
-
-
Iyer, J.1
Tsai, M.Y.2
-
80
-
-
4644265572
-
Determinants for Aurora - A activation and Aurora-B discrimination by TPX2
-
Bayliss R, Sardon T, Ebert J, Lindner D, Vernos I, Conti E (2004) Determinants for Aurora-A activation and Aurora-B discrimination by TPX2. Cell Cycle 3(4):404-407
-
(2004)
Cell Cycle
, vol.3
, Issue.4
, pp. 404-407
-
-
Bayliss, R.1
Sardon, T.2
Ebert, J.3
Lindner, D.4
Vernos, I.5
Conti, E.6
-
81
-
-
48249109896
-
Building a spindle of the correct length in human cells requires the interaction between TPX2 and Aurora A
-
Bird AW, Hyman AA (2008) Building a spindle of the correct length in human cells requires the interaction between TPX2 and Aurora A. J Cell Biol 182(2):289-300
-
(2008)
J Cell Biol
, vol.182
, Issue.2
, pp. 289-300
-
-
Bird, A.W.1
Hyman, A.A.2
-
82
-
-
28444447726
-
Aurora A kinase-coated beads function as microtubule-organizing centers and enhance RanGTP-induced spindle assembly
-
Tsai MY, Zheng Y (2005) Aurora A kinase-coated beads function as microtubule-organizing centers and enhance RanGTP-induced spindle assembly. Curr Biol 15(23):2156-2163
-
(2005)
Curr Biol
, vol.15
, Issue.23
, pp. 2156-2163
-
-
Tsai, M.Y.1
Zheng, Y.2
-
83
-
-
33646024346
-
HURP is part of a Ran-dependent complex involved in spindle formation
-
Koffa MD, Casanova CM, Santarella R, Kocher T, Wilm M, Mattaj IW (2006) HURP is part of a Ran-dependent complex involved in spindle formation. Curr Biol 16(8):743-754
-
(2006)
Curr Biol
, vol.16
, Issue.8
, pp. 743-754
-
-
Koffa, M.D.1
Casanova, C.M.2
Santarella, R.3
Kocher, T.4
Wilm, M.5
Mattaj, I.W.6
-
84
-
-
33646061361
-
HURP is a Ran-importin beta-regulated protein that stabilizes kinetochore microtubules in the vicinity of chromosomes
-
Sillje HH, Nagel S, Korner R, Nigg EA (2006) HURP is a Ran-importin beta-regulated protein that stabilizes kinetochore microtubules in the vicinity of chromosomes. Curr Biol 16(8):731-742
-
(2006)
Curr Biol
, vol.16
, Issue.8
, pp. 731-742
-
-
Sillje, H.H.1
Nagel, S.2
Korner, R.3
Nigg, E.A.4
-
85
-
-
14644419063
-
Proteome analysis of the human mitotic spindle
-
Sauer G, Korner R, Hanisch A, Ries A, Nigg EA, Sillje HH (2005) Proteome analysis of the human mitotic spindle. Mol Cell Proteomics 4(1):35-43
-
(2005)
Mol Cell Proteomics
, vol.4
, Issue.1
, pp. 35-43
-
-
Sauer, G.1
Korner, R.2
Hanisch, A.3
Ries, A.4
Nigg, E.A.5
Sillje, H.H.6
-
86
-
-
79959735228
-
Quantitative phosphoproteomics identifies substrates and functional modules of Aurora and Polo-like kinase activities in mitotic cells
-
Kettenbach AN, Schweppe DK, Faherty BK, Pechenick D, Pletnev AA, Gerber SA (2011) Quantitative phosphoproteomics identifies substrates and functional modules of Aurora and Polo-like kinase activities in mitotic cells. Sci Signal 4(179):rs5
-
(2011)
Sci Signal
, vol.4
, Issue.179
-
-
Kettenbach, A.N.1
Schweppe, D.K.2
Faherty, B.K.3
Pechenick, D.4
Pletnev, A.A.5
Gerber, S.A.6
-
87
-
-
78649470597
-
Uncovering new substrates for Aurora A kinase
-
Sardon T, Pache RA, Stein A, Molina H, Vernos I, Aloy P (2010) Uncovering new substrates for Aurora A kinase. EMBO Rep 11(12):977-984
-
(2010)
EMBO Rep
, vol.11
, Issue.12
, pp. 977-984
-
-
Sardon, T.1
Pache, R.A.2
Stein, A.3
Molina, H.4
Vernos, I.5
Aloy, P.6
-
88
-
-
0033591432
-
The Xenopus laevis aurora-related protein kinase peg2 associates with and phosphorylates the kinesin-related protein Xleg5
-
Giet R, Uzbekov R, Cubizolles F, Le Guellec K, Prigent C (1999) The Xenopus laevis aurora-related protein kinase peg2 associates with and phosphorylates the kinesin-related protein Xleg5. J Biol Chem 274(21):15005-15013
-
(1999)
J Biol Chem
, vol.274
, Issue.21
, pp. 15005-15013
-
-
Giet, R.1
Uzbekov, R.2
Cubizolles, F.3
Le Guellec, K.4
Prigent, C.5
-
89
-
-
0034631960
-
The Xenopus laevis aurora/Ip11p-related kinase peg2 participates in the stability of the bipolar mitotic spindle
-
Giet R, Prigent C (2000) The Xenopus laevis aurora/Ip11p-related kinase peg2 participates in the stability of the bipolar mitotic spindle. Exp Cell Res 258(1):145-151
-
(2000)
Exp Cell Res
, vol.258
, Issue.1
, pp. 145-151
-
-
Giet, R.1
Prigent, C.2
-
90
-
-
18344371892
-
The bipolar mitotic kinesin eg5 moves on both microtubules that it crosslinks
-
Kapitein LC, Peterman EJ, Kwok BH, Kim JH, Kapoor TM, Schmidt CF (2005) The bipolar mitotic kinesin eg5 moves on both microtubules that it crosslinks. Nature 435(7038):114-118
-
(2005)
Nature
, vol.435
, Issue.7038
, pp. 114-118
-
-
Kapitein, L.C.1
Peterman, E.J.2
Kwok, B.H.3
Kim, J.H.4
Kapoor, T.M.5
Schmidt, C.F.6
-
92
-
-
0035090387
-
Ran stimulates spindle assembly by altering microtubule dynamics and the balance of motor activities
-
Wilde A, Lizarraga SB, Zhang L, Wiese C, Gliksman NR, Walczak CE, Zheng Y (2001) Ran stimulates spindle assembly by altering microtubule dynamics and the balance of motor activities. Nat Cell Biol 3(3):221-227
-
(2001)
Nat Cell Biol
, vol.3
, Issue.3
, pp. 221-227
-
-
Wilde, A.1
Lizarraga, S.B.2
Zhang, L.3
Wiese, C.4
Gliksman, N.R.5
Walczak, C.E.6
Zheng, Y.7
-
93
-
-
77949462065
-
Poleward transport of TPX2 in the mammalian mitotic spindle requires dynein, eg5, and microtubule flux
-
Ma N, Tulu US, Ferenz NP, Fagerstrom C, Wilde A, Wadsworth P (2010) Poleward transport of TPX2 in the mammalian mitotic spindle requires dynein, eg5, and microtubule flux. Mol Biol Cell 21(6):979-988
-
(2010)
Mol Biol Cell
, vol.21
, Issue.6
, pp. 979-988
-
-
Ma, N.1
Tulu, U.S.2
Ferenz, N.P.3
Fagerstrom, C.4
Wilde, A.5
Wadsworth, P.6
-
94
-
-
80053950123
-
TPX2 regulates the localization and activity of eg5 in the mammalian mitotic spindle
-
Ma N, Titus J, Gable A, Ross JL, Wadsworth P (2011) TPX2 regulates the localization and activity of eg5 in the mammalian mitotic spindle. J Cell Biol 195(1):87-98
-
(2011)
J Cell Biol
, vol.195
, Issue.1
, pp. 87-98
-
-
Ma, N.1
Titus, J.2
Gable, A.3
Ross, J.L.4
Wadsworth, P.5
-
95
-
-
21744453954
-
Phosphorylation and stabilization of HURP by Aurora-A: Implication of HURP as a transforming target of Aurora-A
-
Yu CT, Hsu JM, Lee YC, Tsou AP, Chou CK, Huang CY (2005) Phosphorylation and stabilization of HURP by Aurora-A: implication of HURP as a transforming target of Aurora-A. Mol Cell Biol 25(14):5789-5800
-
(2005)
Mol Cell Biol
, vol.25
, Issue.14
, pp. 5789-5800
-
-
Yu, C.T.1
Hsu, J.M.2
Lee, Y.C.3
Tsou, A.P.4
Chou, C.K.5
Huang, C.Y.6
-
96
-
-
84877317722
-
Aurora kinase inhibitors reveal mechanisms of HURP in nucleation of centrosomal and kinetochore microtubules
-
Wu JM, Chen CT, Coumar MS, Lin WH, Chen ZJ, Hsu JT, Peng YH, Shiao HY, Chu CY, Wu JS, Lin CT, Chen CP, Hsueh CC, Chang KY, Kao LP, Huang CY, Chao YS, Wu SY, Hsieh HP, Chi YH (2013) Aurora kinase inhibitors reveal mechanisms of HURP in nucleation of centrosomal and kinetochore microtubules. Proc Natl Acad Sci USA 110(19):e1779-e1787
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, Issue.19
-
-
Wu, J.M.1
Chen, C.T.2
Coumar, M.S.3
Lin, W.H.4
Chen, Z.J.5
Hsu, J.T.6
Peng, Y.H.7
Shiao, H.Y.8
Chu, C.Y.9
Wu, J.S.10
Lin, C.T.11
Chen, C.P.12
Hsueh, C.C.13
Chang, K.Y.14
Kao, L.P.15
Huang, C.Y.16
Chao, Y.S.17
Wu, S.Y.18
Hsieh, H.P.19
Chi, Y.H.20
more..
-
97
-
-
33845697790
-
Phospho-regulation of human protein kinase Aurora-A: Analysis using anti-phospho-Thr288 monoclonal antibodies
-
Ohashi S, Sakashita G, Ban R, Nagasawa M, Matsuzaki H, Murata Y, Taniguchi H, Shima H, Furukawa K, Urano T (2006) Phospho-regulation of human protein kinase Aurora-A: analysis using anti-phospho-Thr288 monoclonal antibodies. Oncogene 25(59):7691-7702
-
(2006)
Oncogene
, vol.25
, Issue.59
, pp. 7691-7702
-
-
Ohashi, S.1
Sakashita, G.2
Ban, R.3
Nagasawa, M.4
Matsuzaki, H.5
Murata, Y.6
Taniguchi, H.7
Shima, H.8
Furukawa, K.9
Urano, T.10
-
98
-
-
78650484299
-
Centrosomal protein of 192 kDa (Cep192) promotes centrosome-driven spindle assembly by engaging in organelle-specific Aurora A activation
-
Joukov V, De Nicolo A, Rodriguez A, Walter JC, Livingston DM (2010) Centrosomal protein of 192 kDa (Cep192) promotes centrosome-driven spindle assembly by engaging in organelle-specific Aurora A activation. Proc Natl Acad Sci USA 107(49):21022-21027
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, Issue.49
, pp. 21022-21027
-
-
Joukov, V.1
De Nicolo, A.2
Rodriguez, A.3
Walter, J.C.4
Livingston, D.M.5
-
99
-
-
36049016731
-
Human Cep192 is required for mitotic centrosome and spindle assembly
-
Gomez-Ferreria MA, Rath U, Buster DW, Chanda SK, Caldwell JS, Rines DR, Sharp DJ (2007) Human Cep192 is required for mitotic centrosome and spindle assembly. Curr Biol 17(22):1960-1966
-
(2007)
Curr Biol
, vol.17
, Issue.22
, pp. 1960-1966
-
-
Gomez-Ferreria, M.A.1
Rath, U.2
Buster, D.W.3
Chanda, S.K.4
Caldwell, J.S.5
Rines, D.R.6
Sharp, D.J.7
-
100
-
-
53749104381
-
Meiotic regulation of TPX2 protein levels governs cell cycle progression in mouse oocytes
-
Brunet S, Dumont J, Lee KW, Kinoshita K, Hikal P, Gruss OJ, Maro B, Verlhac MH (2008) Meiotic regulation of TPX2 protein levels governs cell cycle progression in mouse oocytes. PLoS ONe 3(10):e3338
-
(2008)
PLoS ONe
, vol.3
, Issue.10
-
-
Brunet, S.1
Dumont, J.2
Lee, K.W.3
Kinoshita, K.4
Hikal, P.5
Gruss, O.J.6
Maro, B.7
Verlhac, M.H.8
-
101
-
-
77954701718
-
Arpc1b, a centrosomal protein, is both an activator and substrate of Aurora A
-
Molli PR, Li DQ, Bagheri-Yarmand R, Pakala SB, Katayama H, Sen S, Iyer J, Chernoff J, Tsai MY, Nair SS, Kumar R (2010) Arpc1b, a centrosomal protein, is both an activator and substrate of Aurora A. J Cell Biol 190(1):101-114
-
(2010)
J Cell Biol
, vol.190
, Issue.1
, pp. 101-114
-
-
Molli, P.R.1
Li, D.Q.2
Bagheri-Yarmand, R.3
Pakala, S.B.4
Katayama, H.5
Sen, S.6
Iyer, J.7
Chernoff, J.8
Tsai, M.Y.9
Nair, S.S.10
Kumar, R.11
-
102
-
-
27144495462
-
The focal adhesion scaffolding protein HEF1 regulates activation of the Aurora - A and Nek2 kinases at the centrosome
-
Pugacheva EN, Golemis EA (2005) The focal adhesion scaffolding protein HEF1 regulates activation of the Aurora-A and Nek2 kinases at the centrosome. Nat Cell Biol 7(10):937-946
-
(2005)
Nat Cell Biol
, vol.7
, Issue.10
, pp. 937-946
-
-
Pugacheva, E.N.1
Golemis, E.A.2
-
103
-
-
26944442735
-
The GIT-associated kinase PAK targets to the centrosome and regulates Aurora - A
-
Zhao ZS, Lim JP, Ng YW, Lim L, Manser E (2005) The GIT-associated kinase PAK targets to the centrosome and regulates Aurora-A. Mol Cell 20(2):237-249
-
(2005)
Mol Cell
, vol.20
, Issue.2
, pp. 237-249
-
-
Zhao, Z.S.1
Lim, J.P.2
Ng, Y.W.3
Lim, L.4
Manser, E.5
-
104
-
-
84858256289
-
Tpx2 controls spindle integrity, genome stability, and tumor development
-
Aguirre-Portoles C, Bird AW, Hyman A, Canamero M, Perez de Castro I, Malumbres M (2012) Tpx2 controls spindle integrity, genome stability, and tumor development. Cancer Res 72(6):1518-1528
-
(2012)
Cancer Res
, vol.72
, Issue.6
, pp. 1518-1528
-
-
Aguirre-Portoles, C.1
Bird, A.W.2
Hyman, A.3
Canamero, M.4
Perez De Castro, I.5
Malumbres, M.6
-
105
-
-
57749083388
-
The plant TPX2 protein regulates prospindle assembly before nuclear envelope breakdown
-
Vos JW, Pieuchot L, Evrard JL, Janski N, Bergdoll M, De Ronde D, Perez LH, Sardon T, Vernos I, Schmit AC (2008) The plant TPX2 protein regulates prospindle assembly before nuclear envelope breakdown. Plant Cell 20(10):2783-2797
-
(2008)
Plant Cell
, vol.20
, Issue.10
, pp. 2783-2797
-
-
Vos, J.W.1
Pieuchot, L.2
Evrard, J.L.3
Janski, N.4
Bergdoll, M.5
De Ronde, D.6
Perez, L.H.7
Sardon, T.8
Vernos, I.9
Schmit, A.C.10
-
106
-
-
84862557239
-
A small molecule inhibitor targeting the mitotic spindle checkpoint impairs the growth of uterine leiomyosarcoma
-
Shan W, Akinfenwa PY, Brewer Savannah K, Kolomeyevskaya N, Laucirica R, Thomas DG, Odunsi K, Creighton CJ, Lev D, Anderson ML (2012) A small molecule inhibitor targeting the mitotic spindle checkpoint impairs the growth of uterine leiomyosarcoma. Clin Cancer Res 18(12):3352-3365
-
(2012)
Clin Cancer Res
, vol.18
, Issue.12
, pp. 3352-3365
-
-
Shan, W.1
Akinfenwa, P.Y.2
Brewer Savannah, K.3
Kolomeyevskaya, N.4
Laucirica, R.5
Thomas, D.G.6
Odunsi, K.7
Creighton, C.J.8
Lev, D.9
Anderson, M.L.10
-
107
-
-
84866974004
-
TPX2 and AURKA promote 20q amplicon-driven colorectal adenoma to carcinoma progression
-
Sillars-Hardebol AH, Carvalho B, Tijssen M, Belien JA, De Wit M, Delis-van Diemen PM, Ponten F, van de Wiel MA, Fijneman RJ, Meijer GA (2012) TPX2 and AURKA promote 20q amplicon-driven colorectal adenoma to carcinoma progression. Gut 61(11):1568-1575
-
(2012)
Gut
, vol.61
, Issue.11
, pp. 1568-1575
-
-
Sillars-Hardebol, A.H.1
Carvalho, B.2
Tijssen, M.3
Belien, J.A.4
De Wit, M.5
Delis-Van Diemen, P.M.6
Ponten, F.7
Van De Wiel, M.A.8
Fijneman, R.J.9
Meijer, G.A.10
-
108
-
-
22144433675
-
High-resolution genomic profiles of human lung cancer
-
Tonon G, Wong KK, Maulik G, Brennan C, Feng B, Zhang Y, Khatry DB, Protopopov A, You MJ, Aguirre AJ, Martin ES, Yang Z, Ji H, Chin L, Depinho RA (2005) High-resolution genomic profiles of human lung cancer. Proc Natl Acad Sci USA 102(27):9625-9630
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, Issue.27
, pp. 9625-9630
-
-
Tonon, G.1
Wong, K.K.2
Maulik, G.3
Brennan, C.4
Feng, B.5
Zhang, Y.6
Khatry, D.B.7
Protopopov, A.8
You, M.J.9
Aguirre, A.J.10
Martin, E.S.11
Yang, Z.12
Ji, H.13
Chin, L.14
Depinho, R.A.15
-
109
-
-
48249143703
-
Identification of copy number gain and overexpressed genes on chromosome arm 20q by an integrative genomic approach in cervical cancer: Potential role in progression
-
Scotto L, Narayan G, Nandula S V, Arias-Pulido H, Subramaniyam S, Schneider A, Kaufmann AM, Wright JD, Pothuri B, Mansukhani M, Murty VV (2008) Identification of copy number gain and overexpressed genes on chromosome arm 20q by an integrative genomic approach in cervical cancer: potential role in progression. Genes Chromosomes Cancer 47(9):755-765
-
(2008)
Genes Chromosomes Cancer
, vol.47
, Issue.9
, pp. 755-765
-
-
Scotto, L.1
Narayan, G.2
Nandula, S.V.3
Arias-Pulido, H.4
Subramaniyam, S.5
Schneider, A.6
Kaufmann, A.M.7
Wright, J.D.8
Pothuri, B.9
Mansukhani, M.10
Murty, V.V.11
-
110
-
-
33748491903
-
20q11.1 amplification in giant-cell tumor of bone: Array CGH, FISH, and association with outcome
-
Smith LT, Mayerson J, Nowak NJ, Suster D, Mohammed N, Long S, Auer H, Jones S, McKeegan C, Young G, Bos G, Plass C, Morrison C (2006) 20q11.1 amplification in giant-cell tumor of bone: array CGH, FISH, and association with outcome. Genes Chromosomes Cancer 45(10):957-966
-
(2006)
Genes Chromosomes Cancer
, vol.45
, Issue.10
, pp. 957-966
-
-
Smith, L.T.1
Mayerson, J.2
Nowak, N.J.3
Suster, D.4
Mohammed, N.5
Long, S.6
Auer, H.7
Jones, S.8
McKeegan, C.9
Young, G.10
Bos, G.11
Plass, C.12
Morrison, C.13
-
111
-
-
78649751900
-
Amplicon-dependent CCNE1 expression is critical for clonogenic survival after cisplatin treatment and is correlated with 20q11 gain in ovarian cancer
-
Etemadmoghadam D, George J, Cowin PA, Cullinane C, Kansara M, Gorringe KL, Smyth GK, Bowtell DD (2010) Amplicon-dependent CCNe1 expression is critical for clonogenic survival after cisplatin treatment and is correlated with 20q11 gain in ovarian cancer. PLoS ONe 5(11):e15498
-
(2010)
PLoS ONe
, vol.5
, Issue.11
-
-
Etemadmoghadam, D.1
George, J.2
Cowin, P.A.3
Cullinane, C.4
Kansara, M.5
Gorringe, K.L.6
Smyth, G.K.7
Bowtell, D.D.8
-
112
-
-
70350743121
-
Validation of TPX2 as a potential therapeutic target in pancreatic cancer cells
-
Warner SL, Stephens BJ, Nwokenkwo S, Hostetter G, Sugeng A, Hidalgo M, Trent JM, Han H, Von Hoff DD (2009) Validation of TPX2 as a potential therapeutic target in pancreatic cancer cells. Clin Cancer Res 15(21):6519-6528
-
(2009)
Clin Cancer Res
, vol.15
, Issue.21
, pp. 6519-6528
-
-
Warner, S.L.1
Stephens, B.J.2
Nwokenkwo, S.3
Hostetter, G.4
Sugeng, A.5
Hidalgo, M.6
Trent, J.M.7
Han, H.8
Von Hoff, D.D.9
-
113
-
-
2942643922
-
Highresolution characterization of the pancreatic adenocarcinoma genome
-
Aguirre AJ, Brennan C, Bailey G, Sinha R, Feng B, Leo C, Zhang Y, Zhang J, Gans JD, Bardeesy N, Cauwels C, Cordon Cardo C, Redston MS, DePinho RA, Chin L (2004) Highresolution characterization of the pancreatic adenocarcinoma genome. Proc Natl Acad Sci USA 101(24):9067-9072
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, Issue.24
, pp. 9067-9072
-
-
Aguirre, A.J.1
Brennan, C.2
Bailey, G.3
Sinha, R.4
Feng, B.5
Leo, C.6
Zhang, Y.7
Zhang, J.8
Gans, J.D.9
Bardeesy, N.10
Cauwels, C.11
Cordon Cardo, C.12
Redston, M.S.13
DePinho, R.A.14
Chin, L.15
-
114
-
-
77956316787
-
Identification of candidate growth promoting genes in ovarian cancer through integrated copy number and expression analysis
-
Ramakrishna M, Williams LH, Boyle SE, Bearfoot JL, Sridhar A, Speed TP, Gorringe KL, Campbell IG (2010) Identification of candidate growth promoting genes in ovarian cancer through integrated copy number and expression analysis. PLoS ONe 5(4):e9983
-
(2010)
PLoS ONe
, vol.5
, Issue.4
-
-
Ramakrishna, M.1
Williams, L.H.2
Boyle, S.E.3
Bearfoot, J.L.4
Sridhar, A.5
Speed, T.P.6
Gorringe, K.L.7
Campbell, I.G.8
-
115
-
-
0032542364
-
Genetic instabilities in human cancers
-
Lengauer C, Kinzler KW, Vogelstein B (1998) Genetic instabilities in human cancers. Nature 396(6712):643-649
-
(1998)
Nature
, vol.396
, Issue.6712
, pp. 643-649
-
-
Lengauer, C.1
Kinzler, K.W.2
Vogelstein, B.3
-
118
-
-
34447094967
-
A census of mitotic cancer genes: New insights into tumor cell biology and cancer therapy
-
Perez de Castro I, De Carcer G, Malumbres M (2007) A census of mitotic cancer genes: new insights into tumor cell biology and cancer therapy. Carcinogenesis 28(5):899-912
-
(2007)
Carcinogenesis
, vol.28
, Issue.5
, pp. 899-912
-
-
Perez De Castro, I.1
De Carcer, G.2
Malumbres, M.3
-
119
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan D, Weinberg RA (2000) The hallmarks of cancer. Cell 100(1):57-70
-
(2000)
Cell
, vol.100
, Issue.1
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
120
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
Hanahan D, Weinberg RA (2011) Hallmarks of cancer: the next generation. Cell 144(5):646-674
-
(2011)
Cell
, vol.144
, Issue.5
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
121
-
-
33748286796
-
A signature of chromosomal instability inferred from gene expression profiles predicts clinical outcome in multiple human cancers
-
Carter SL, Eklund AC, Kohane IS, Harris LN, Szallasi Z (2006) A signature of chromosomal instability inferred from gene expression profiles predicts clinical outcome in multiple human cancers. Nat Genet 38(9):1043-1048
-
(2006)
Nat Genet
, vol.38
, Issue.9
, pp. 1043-1048
-
-
Carter, S.L.1
Eklund, A.C.2
Kohane, I.S.3
Harris, L.N.4
Szallasi, Z.5
-
122
-
-
33751085368
-
Overexpression of aurora kinase A in mouse mammary epithelium induces genetic instability preceding mammary tumor formation
-
Wang X, Zhou YX, Qiao W, Tominaga Y, Ouchi M, Ouchi T, Deng CX (2006) Overexpression of aurora kinase A in mouse mammary epithelium induces genetic instability preceding mammary tumor formation. Oncogene 25(54):7148-7158
-
(2006)
Oncogene
, vol.25
, Issue.54
, pp. 7148-7158
-
-
Wang, X.1
Zhou, Y.X.2
Qiao, W.3
Tominaga, Y.4
Ouchi, M.5
Ouchi, T.6
Deng, C.X.7
-
123
-
-
9944220985
-
Cre-loxP-controlled periodic Aurora - A overexpression induces mitotic abnormalities and hyperplasia in mammary glands of mouse models
-
Zhang D, Hirota T, Marumoto T, Shimizu M, Kunitoku N, Sasayama T, Arima Y, Feng L, Suzuki M, Takeya M, Saya H (2004) Cre-loxP-controlled periodic Aurora-A overexpression induces mitotic abnormalities and hyperplasia in mammary glands of mouse models. Oncogene 23(54):8720-8730
-
(2004)
Oncogene
, vol.23
, Issue.54
, pp. 8720-8730
-
-
Zhang, D.1
Hirota, T.2
Marumoto, T.3
Shimizu, M.4
Kunitoku, N.5
Sasayama, T.6
Arima, Y.7
Feng, L.8
Suzuki, M.9
Takeya, M.10
Saya, H.11
-
124
-
-
58149329013
-
Pdx-1-driven overexpression of aurora a kinase induces mild ductal dysplasia of pancreatic ducts near islets in transgenic mice
-
Warner SL, Munoz RM, Bearss DJ, Grippo P, Han H, Von Hoff DD (2008) Pdx-1-driven overexpression of aurora a kinase induces mild ductal dysplasia of pancreatic ducts near islets in transgenic mice. Pancreas 37(3):e39-e44
-
(2008)
Pancreas
, vol.37
, Issue.3
-
-
Warner, S.L.1
Munoz, R.M.2
Bearss, D.J.3
Grippo, P.4
Han, H.5
Von Hoff, D.D.6
-
125
-
-
0037084163
-
Aurora - A overexpression reveals tetraploidization as a major route to centrosome amplification in p53-/- cells
-
Meraldi P, Honda R, Nigg EA (2002) Aurora-A overexpression reveals tetraploidization as a major route to centrosome amplification in p53-/- cells. EMBO J 21(4):483-492
-
(2002)
EMBO J
, vol.21
, Issue.4
, pp. 483-492
-
-
Meraldi, P.1
Honda, R.2
Nigg, E.A.3
-
126
-
-
70450228455
-
A cancer-associated aurora A mutant is mislocalized and misregulated due to loss of interaction with TPX2
-
Bibby RA, Tang C, Faisal A, Drosopoulos K, Lubbe S, Houlston R, Bayliss R, Linardopoulos S (2009) A cancer-associated aurora A mutant is mislocalized and misregulated due to loss of interaction with TPX2. J Biol Chem 284(48):33177-33184
-
(2009)
J Biol Chem
, vol.284
, Issue.48
, pp. 33177-33184
-
-
Bibby, R.A.1
Tang, C.2
Faisal, A.3
Drosopoulos, K.4
Lubbe, S.5
Houlston, R.6
Bayliss, R.7
Linardopoulos, S.8
-
127
-
-
77951721529
-
Combined functional genome survey of therapeutic targets for hepatocellular carcinoma
-
Satow R, Shitashige M, Kanai Y, Takeshita F, Ojima H, Jigami T, Honda K, Kosuge T, Ochiya T, Hirohashi S, Yamada T (2010) Combined functional genome survey of therapeutic targets for hepatocellular carcinoma. Clin Cancer Res 16(9):2518-2528
-
(2010)
Clin Cancer Res
, vol.16
, Issue.9
, pp. 2518-2528
-
-
Satow, R.1
Shitashige, M.2
Kanai, Y.3
Takeshita, F.4
Ojima, H.5
Jigami, T.6
Honda, K.7
Kosuge, T.8
Ochiya, T.9
Hirohashi, S.10
Yamada, T.11
-
128
-
-
34249285532
-
Identification of Ras-related nuclear protein, targeting protein for xenopus kinesin-like protein 2, and stearoyl-CoA desaturase 1 as promising cancer targets from an RNAi-based screen
-
Morgan-Lappe SE, Tucker LA, Huang X, Zhang Q, Sarthy AV, Zakula D, Vernetti L, Schurdak M, Wang J, Fesik SW (2007) Identification of Ras-related nuclear protein, targeting protein for xenopus kinesin-like protein 2, and stearoyl-CoA desaturase 1 as promising cancer targets from an RNAi-based screen. Cancer Res 67(9):4390-4398
-
(2007)
Cancer Res
, vol.67
, Issue.9
, pp. 4390-4398
-
-
Morgan-Lappe, S.E.1
Tucker, L.A.2
Huang, X.3
Zhang, Q.4
Sarthy, A.V.5
Zakula, D.6
Vernetti, L.7
Schurdak, M.8
Wang, J.9
Fesik, S.W.10
-
129
-
-
84863294054
-
The TPX2 gene is a promising diagnostic and therapeutic target for cervical cancer
-
Chang H, Wang J, Tian Y, Xu J, Gou X, Cheng J (2012) The TPX2 gene is a promising diagnostic and therapeutic target for cervical cancer. Oncol Rep 27(5):1353-1359
-
(2012)
Oncol Rep
, vol.27
, Issue.5
, pp. 1353-1359
-
-
Chang, H.1
Wang, J.2
Tian, Y.3
Xu, J.4
Gou, X.5
Cheng, J.6
-
130
-
-
77957244417
-
Quantitative analysis of conditional gene inactivation using rationally designed, tetracycline-controlled miRNAs
-
Berger SM, Pesold B, Reber S, Schonig K, Berger AJ, Weidenfeld I, Miao J, Berger MR, Gruss OJ, Bartsch D (2010) Quantitative analysis of conditional gene inactivation using rationally designed, tetracycline-controlled miRNAs. Nucleic Acids Res 38(17):e168
-
(2010)
Nucleic Acids Res
, vol.38
, Issue.17
-
-
Berger, S.M.1
Pesold, B.2
Reber, S.3
Schonig, K.4
Berger, A.J.5
Weidenfeld, I.6
Miao, J.7
Berger, M.R.8
Gruss, O.J.9
Bartsch, D.10
-
131
-
-
1942438028
-
Microtubules as a target for anticancer drugs
-
Jordan MA, Wilson L (2004) Microtubules as a target for anticancer drugs. Nat Rev Cancer 4(4):253-265
-
(2004)
Nat Rev Cancer
, vol.4
, Issue.4
, pp. 253-265
-
-
Jordan, M.A.1
Wilson, L.2
-
132
-
-
78249270765
-
Short exposure to paclitaxel induces multipolar spindle formation and aneuploidy through promotion of acentrosomal pole assembly
-
Bian M, Fu J, Yan Y, Chen Q, Yang C, Shi Q, Jiang Q, Zhang C (2010) Short exposure to paclitaxel induces multipolar spindle formation and aneuploidy through promotion of acentrosomal pole assembly. Sci China Life Sci 53(11):1322-1329
-
(2010)
Sci China Life Sci
, vol.53
, Issue.11
, pp. 1322-1329
-
-
Bian, M.1
Fu, J.2
Yan, Y.3
Chen, Q.4
Yang, C.5
Shi, Q.6
Jiang, Q.7
Zhang, C.8
-
133
-
-
50049085789
-
Mechanisms to suppress multipolar divisions in cancer cells with extra centrosomes
-
Kwon M, Godinho SA, Chandhok NS, Ganem NJ, Azioune A, Thery M, Pellman D (2008) Mechanisms to suppress multipolar divisions in cancer cells with extra centrosomes. Genes Dev 22(16):2189-2203
-
(2008)
Genes Dev
, vol.22
, Issue.16
, pp. 2189-2203
-
-
Kwon, M.1
Godinho, S.A.2
Chandhok, N.S.3
Ganem, N.J.4
Azioune, A.5
Thery, M.6
Pellman, D.7
-
134
-
-
84891485343
-
Target protein for Xklp2 (TPX2), a microtubule-related protein, contributes to malignant phenotype in bladder carcinoma
-
Yan L, Li S, Xu C, Zhao X, Hao B, Li H, Qiao B (2013) Target protein for Xklp2 (TPX2), a microtubule-related protein, contributes to malignant phenotype in bladder carcinoma. Tumour Biol 34(6):4089-4100
-
(2013)
Tumour Biol
, vol.34
, Issue.6
, pp. 4089-4100
-
-
Yan, L.1
Li, S.2
Xu, C.3
Zhao, X.4
Hao, B.5
Li, H.6
Qiao, B.7
-
135
-
-
53249087832
-
TPX2 in malignantly transformed human bronchial epithelial cells by anti-benzo[a]pyrene-7,8-diol-9,10-epoxide
-
Zhang L, Huang H, Deng L, Chu M, Xu L, Fu J, Zhu Y, Zhang X, Liu S, Zhou Z, Wang Y (2008) TPX2 in malignantly transformed human bronchial epithelial cells by anti-benzo[a]pyrene-7,8-diol-9,10-epoxide. Toxicology 252(1-3):49-55
-
(2008)
Toxicology
, vol.252
, Issue.1-3
, pp. 49-55
-
-
Zhang, L.1
Huang, H.2
Deng, L.3
Chu, M.4
Xu, L.5
Fu, J.6
Zhu, Y.7
Zhang, X.8
Liu, S.9
Zhou, Z.10
Wang, Y.11
-
136
-
-
84856373697
-
Ashwagandha derived withanone targets TPX2-Aurora A complex: Computational and experimental evidence to its anticancer activity
-
Grover A, Singh R, Shandilya A, Priyandoko D, Agrawal V, Bisaria VS, Wadhwa R, Kaul SC, Sundar D (2012) Ashwagandha derived withanone targets TPX2-Aurora A complex: computational and experimental evidence to its anticancer activity. PLoS ONe 7(1):e30890
-
(2012)
PLoS ONe
, vol.7
, Issue.1
-
-
Grover, A.1
Singh, R.2
Shandilya, A.3
Priyandoko, D.4
Agrawal, V.5
Bisaria, V.S.6
Wadhwa, R.7
Kaul, S.C.8
Sundar, D.9
-
137
-
-
78149427794
-
Selective killing of cancer cells by Ashwagandha leaf extract and its component withanone involves ROS signaling
-
Widodo N, Priyandoko D, Shah N, Wadhwa R, Kaul SC (2010) Selective killing of cancer cells by Ashwagandha leaf extract and its component withanone involves ROS signaling. PLoS ONe 5(10):e13536
-
(2010)
PLoS ONe
, vol.5
, Issue.10
-
-
Widodo, N.1
Priyandoko, D.2
Shah, N.3
Wadhwa, R.4
Kaul, S.C.5
-
138
-
-
84857232029
-
Withanone binds to mortalin and abrogates mortalin-p53 complex: Computational and experimental evidence
-
Grover A, Priyandoko D, Gao R, Shandilya A, Widodo N, Bisaria VS, Kaul SC, Wadhwa R, Sundar D (2012) Withanone binds to mortalin and abrogates mortalin-p53 complex: computational and experimental evidence. Int J Biochem Cell Biol 44(3):496-504
-
(2012)
Int J Biochem Cell Biol
, vol.44
, Issue.3
, pp. 496-504
-
-
Grover, A.1
Priyandoko, D.2
Gao, R.3
Shandilya, A.4
Widodo, N.5
Bisaria, V.S.6
Kaul, S.C.7
Wadhwa, R.8
Sundar, D.9
-
139
-
-
66149115276
-
Dynamic release of nuclear RanGTP triggers TPX2-dependent microtubule assembly during the apoptotic execution phase
-
Moss DK, Wilde A, Lane JD (2009) Dynamic release of nuclear RanGTP triggers TPX2-dependent microtubule assembly during the apoptotic execution phase. J Cell Sci 122(Pt 5):644-655
-
(2009)
J Cell Sci
, vol.122
, Issue.PART 5
, pp. 644-655
-
-
Moss, D.K.1
Wilde, A.2
Lane, J.D.3
-
140
-
-
84871307587
-
Targeting protein for Xenopus kinesin like protein 2 (TPX2) regulates gamma-H2AX levels upon ionizing radiation
-
Neumayer G, Helfricht A, Shim SY, Le HT, Lundin C, Belzil C, Chansard M, Yu Y, Lees-Miller SP, Gruss O, van Attikum H, Helleday T, Nguyen MD (2012) Targeting protein for Xenopus kinesin like protein 2 (TPX2) regulates gamma-H2AX levels upon ionizing radiation. J Biol Chem 287(50):42206-42222
-
(2012)
J Biol Chem
, vol.287
, Issue.50
, pp. 42206-42222
-
-
Neumayer, G.1
Helfricht, A.2
Shim, S.Y.3
Le, H.T.4
Lundin, C.5
Belzil, C.6
Chansard, M.7
Yu, Y.8
Lees-Miller, S.P.9
Gruss, O.10
Van Attikum, H.11
Helleday, T.12
Nguyen, M.D.13
-
141
-
-
45849099050
-
Living on a break: Cellular senescence as a DNA-damage response
-
D'Adda di Fagagna F (2008) Living on a break: cellular senescence as a DNA-damage response. Nat Rev Cancer 8(7):512-522
-
(2008)
Nat Rev Cancer
, vol.8
, Issue.7
, pp. 512-522
-
-
D'Adda Di Fagagna, F.1
-
142
-
-
82455175797
-
Interplay between BRCA1 and RHAMM regulates epithelial apicobasal polarization and may influence risk of breast cancer
-
Maxwell CA, Benitez J, Gomez-Baldo L, Osorio A, Bonifaci N, Fernandez-Ramires R, Costes SV, Guino E, Chen H, Evans GJ, Mohan P, Catala I, Petit A, Aguilar H, Villanueva A, Aytes A, Serra-Musach J, Rennert G, Lejbkowicz F, Peterlongo P, Manoukian S, Peissel B, Ripamonti CB, Bonanni B, Viel A, Allavena A, Bernard L, Radice P, Friedman E, Kaufman B, Laitman Y, Dubrovsky M, Milgrom R, Jakubowska A, Cybulski C, Gorski B, Jaworska K, Durda K, Sukiennicki G, Lubinski J, Shugart YY, Domchek SM, Letrero R, Weber BL, Hogervorst FB, Rookus MA, Collee JM, Devilee P, Ligtenberg MJ, Luijt RB, Aalfs CM, Waisfisz Q, Wijnen J, Roozendaal CE, Easton DF, Peock S, Cook M, Oliver C, Frost D, Harrington P, Evans DG, Lalloo F, Eeles R, Izatt L, Chu C, Eccles D, Douglas F, Brewer C, Nevanlinna H, Heikkinen T, Couch FJ, Lindor NM, Wang X, Godwin AK, Caligo MA, Lombardi G, Loman N, Karlsson P, Ehrencrona H, Wachenfeldt A, Barkardottir RB, Hamann U, Rashid MU, Lasa A, Caldes T, Andres R, Schmitt M, Assmann V, Stevens K, Offit K, Curado J, Tilgner H, Guigo R, Aiza G, Brunet J, Castellsague J, Martrat G, Urruticoechea A, Blanco I, Tihomirova L, Goldgar DE, Buys S, John EM, Miron A, Southey M, Daly MB, Schmutzler RK, Wappenschmidt B, Meindl A, Arnold N, Deissler H, Varon-Mateeva R, Sutter C, Niederacher D, Imyamitov E, Sinilnikova OM, Stoppa-Lyonne D, Mazoyer S, Verny-Pierre C, Castera L, De Pauw A, Bignon YJ, Uhrhammer N, Peyrat JP, Vennin P, Fert Ferrer S, Collonge-Rame MA, Mortemousque I, Spurdle AB, Beesley J, Chen X, Healey S, Barcellos-Hoff MH, Vidal M, Gruber SB, Lazaro C, Capella G, McGuffog L, Nathanson KL, Antoniou AC, Chenevix-Trench G, Fleisch MC, Moreno V, Pujana MA (2011) Interplay between BRCA1 and RHAMM regulates epithelial apicobasal polarization and may influence risk of breast cancer. PLoS Biol 9(11):e1001199
-
(2011)
PLoS Biol
, vol.9
, Issue.11
-
-
Maxwell, C.A.1
Benitez, J.2
Gomez-Baldo, L.3
Osorio, A.4
Bonifaci, N.5
Fernandez-Ramires, R.6
Costes, S.V.7
Guino, E.8
Chen, H.9
Evans, G.J.10
Mohan, P.11
Catala, I.12
Petit, A.13
Aguilar, H.14
Villanueva, A.15
Aytes, A.16
Serra-Musach, J.17
Rennert, G.18
Lejbkowicz, F.19
Peterlongo, P.20
Manoukian, S.21
Peissel, B.22
Ripamonti, C.B.23
Bonanni, B.24
Viel, A.25
Allavena, A.26
Bernard, L.27
Radice, P.28
Friedman, E.29
Kaufman, B.30
Laitman, Y.31
Dubrovsky, M.32
Milgrom, R.33
Jakubowska, A.34
Cybulski, C.35
Gorski, B.36
Jaworska, K.37
Durda, K.38
Sukiennicki, G.39
Lubinski, J.40
Shugart, Y.Y.41
Domchek, S.M.42
Letrero, R.43
Weber, B.L.44
Hogervorst, F.B.45
Rookus, M.A.46
Collee, J.M.47
Devilee, P.48
Ligtenberg, M.J.49
Luijt, R.B.50
Aalfs, C.M.51
Waisfisz, Q.52
Wijnen, J.53
Roozendaal, C.E.54
Easton, D.F.55
Peock, S.56
Cook, M.57
Oliver, C.58
Frost, D.59
Harrington, P.60
Evans, D.G.61
Lalloo, F.62
Eeles, R.63
Izatt, L.64
Chu, C.65
Eccles, D.66
Douglas, F.67
Brewer, C.68
Nevanlinna, H.69
Heikkinen, T.70
Couch, F.J.71
Lindor, N.M.72
Wang, X.73
Godwin, A.K.74
Caligo, M.A.75
Lombardi, G.76
Loman, N.77
Karlsson, P.78
Ehrencrona, H.79
Wachenfeldt, A.80
Barkardottir, R.B.81
Hamann, U.82
Rashid, M.U.83
Lasa, A.84
Caldes, T.85
Andres, R.86
Schmitt, M.87
Assmann, V.88
Stevens, K.89
Offit, K.90
Curado, J.91
Tilgner, H.92
Guigo, R.93
Aiza, G.94
Brunet, J.95
Castellsague, J.96
Martrat, G.97
Urruticoechea, A.98
Blanco, I.99
Tihomirova, L.100
more..
-
143
-
-
34249947699
-
ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage
-
Matsuoka S, Ballif BA, Smogorzewska A, McDonald Er III, Hurov KE, Luo J, Bakalarski CE, Zhao Z, Solimini N, Lerenthal Y, Shiloh Y, Gygi SP, Elledge SJ (2007) ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage. Science 316(5828):1160-1166
-
(2007)
Science
, vol.316
, Issue.5828
, pp. 1160-1166
-
-
Matsuoka, S.1
Ballif, B.A.2
Smogorzewska, A.3
McDonald Er, I.I.I.4
Hurov, K.E.5
Luo, J.6
Bakalarski, C.E.7
Zhao, Z.8
Solimini, N.9
Lerenthal, Y.10
Shiloh, Y.11
Gygi, S.P.12
Elledge, S.J.13
-
144
-
-
77951985216
-
Examination of the expanding pathways for the regulation of p21 expression and activity
-
Jung YS, Qian Y, Chen X (2010) Examination of the expanding pathways for the regulation of p21 expression and activity. Cell Signal 22(7):1003-1012
-
(2010)
Cell Signal
, vol.22
, Issue.7
, pp. 1003-1012
-
-
Jung, Y.S.1
Qian, Y.2
Chen, X.3
-
145
-
-
0032553485
-
Requirement for p53 and p21 to sustain G2 arrest after DNA damage
-
Bunz F, Dutriaux A, Lengauer C, Waldman T, Zhou S, Brown JP, Sedivy JM, Kinzler KW, Vogelstein B (1998) Requirement for p53 and p21 to sustain G2 arrest after DNA damage. Science 282(5393):1497-1501
-
(1998)
Science
, vol.282
, Issue.5393
, pp. 1497-1501
-
-
Bunz, F.1
Dutriaux, A.2
Lengauer, C.3
Waldman, T.4
Zhou, S.5
Brown, J.P.6
Sedivy, J.M.7
Kinzler, K.W.8
Vogelstein, B.9
-
146
-
-
0028849274
-
P21 is necessary for the p53-mediated G1 arrest in human cancer cells
-
Waldman T, Kinzler KW, Vogelstein B (1995) P21 is necessary for the p53-mediated G1 arrest in human cancer cells. Cancer Res 55(22):5187-5190
-
(1995)
Cancer Res
, vol.55
, Issue.22
, pp. 5187-5190
-
-
Waldman, T.1
Kinzler, K.W.2
Vogelstein, B.3
-
147
-
-
65149084552
-
Crosstalk between histone modifications during the DNA damage response
-
van Attikum H, Gasser SM (2009) Crosstalk between histone modifications during the DNA damage response. Trends Cell Biol 19(5):207-217
-
(2009)
Trends Cell Biol
, vol.19
, Issue.5
, pp. 207-217
-
-
Van Attikum, H.1
Gasser, S.M.2
-
148
-
-
0032861343
-
Megabase chromatin domains involved in DNA double-strand breaks in vivo
-
Rogakou EP, Boon C, Redon C, Bonner WM (1999) Megabase chromatin domains involved in DNA double-strand breaks in vivo. J Cell Biol 146(5):905-916
-
(1999)
J Cell Biol
, vol.146
, Issue.5
, pp. 905-916
-
-
Rogakou, E.P.1
Boon, C.2
Redon, C.3
Bonner, W.M.4
-
149
-
-
0032489520
-
DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139
-
Rogakou EP, Pilch DR, Orr AH, Ivanova VS, Bonner WM (1998) DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139. J Biol Chem 273(10):5858-5868
-
(1998)
J Biol Chem
, vol.273
, Issue.10
, pp. 5858-5868
-
-
Rogakou, E.P.1
Pilch, D.R.2
Orr, A.H.3
Ivanova, V.S.4
Bonner, W.M.5
-
150
-
-
42249102663
-
Gammah2Ax foci form preferentially in euchromatin after ionising-radiation
-
Cowell IG, Sunter NJ, Singh PB, Austin CA, Durkacz BW, Tilby MJ (2007) Gammah2Ax foci form preferentially in euchromatin after ionising-radiation. PLoS ONe 2(10):e1057
-
(2007)
PLoS ONe
, vol.2
, Issue.10
-
-
Cowell, I.G.1
Sunter, N.J.2
Singh, P.B.3
Austin, C.A.4
Durkacz, B.W.5
Tilby, M.J.6
-
151
-
-
34447532525
-
Heterochromatin is refractory to gamma-H2AX modification in yeast and mammals
-
Kim JA, Kruhlak M, Dotiwala F, Nussenzweig A, Haber JE (2007) Heterochromatin is refractory to gamma-H2AX modification in yeast and mammals. J Cell Biol 178(2):209-218
-
(2007)
J Cell Biol
, vol.178
, Issue.2
, pp. 209-218
-
-
Kim, J.A.1
Kruhlak, M.2
Dotiwala, F.3
Nussenzweig, A.4
Haber, J.E.5
-
152
-
-
80052567822
-
BRCA1 tumour suppression occurs via heterochromatin-mediated silencing
-
Zhu Q, Pao GM, Huynh AM, Suh H, Tonnu N, Nederlof PM, Gage FH, Verma IM (2011) BRCA1 tumour suppression occurs via heterochromatin-mediated silencing. Nature 477(7363):179-184
-
(2011)
Nature
, vol.477
, Issue.7363
, pp. 179-184
-
-
Zhu, Q.1
Pao, G.M.2
Huynh, A.M.3
Suh, H.4
Tonnu, N.5
Nederlof, P.M.6
Gage, F.H.7
Verma, I.M.8
-
153
-
-
33644772547
-
Expression of targeting protein for xklp2 associated with both malignant transformation of respiratory epithelium and progression of squamous cell lung cancer
-
Ma Y, Lin D, Sun W, Xiao T, Yuan J, Han N, Guo S, Feng X, Su K, Mao Y, Cheng S, Gao Y (2006) Expression of targeting protein for xklp2 associated with both malignant transformation of respiratory epithelium and progression of squamous cell lung cancer. Clin Cancer Res 12(4):1121-1127
-
(2006)
Clin Cancer Res
, vol.12
, Issue.4
, pp. 1121-1127
-
-
Ma, Y.1
Lin, D.2
Sun, W.3
Xiao, T.4
Yuan, J.5
Han, N.6
Guo, S.7
Feng, X.8
Su, K.9
Mao, Y.10
Cheng, S.11
Gao, Y.12
-
154
-
-
77956179982
-
Expression of targeting protein for Xenopus kinesin-like protein 2 is associated with progression of human malignant astrocytoma
-
Li B, Qi XQ, Chen X, Huang X, Liu GY, Chen HR, Huang CG, Luo C, Lu YC (2010) Expression of targeting protein for Xenopus kinesin-like protein 2 is associated with progression of human malignant astrocytoma. Brain Res 1352:200-207
-
(2010)
Brain Res
, vol.1352
, pp. 200-207
-
-
Li, B.1
Qi, X.Q.2
Chen, X.3
Huang, X.4
Liu, G.Y.5
Chen, H.R.6
Huang, C.G.7
Luo, C.8
Lu, Y.C.9
-
155
-
-
84863157850
-
Integrated cross-species transcriptional network analysis of metastatic susceptibility
-
Hu Y, Wu G, Rusch M, Lukes L, Buetow KH, Zhang J, Hunter KW (2012) Integrated cross-species transcriptional network analysis of metastatic susceptibility. Proc Natl Acad Sci USA 109(8):3184-3189
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, Issue.8
, pp. 3184-3189
-
-
Hu, Y.1
Wu, G.2
Rusch, M.3
Lukes, L.4
Buetow, K.H.5
Zhang, J.6
Hunter, K.W.7
-
156
-
-
0037448686
-
Identification of a novel cell cycle regulated gene, HURP, overexpressed in human hepatocellular carcinoma
-
Tsou AP, Yang CW, Huang CY, Yu RC, Lee YC, Chang CW, Chen BR, Chung YF, Fann MJ, Chi CW, Chiu JH, Chou CK (2003) Identification of a novel cell cycle regulated gene, HURP, overexpressed in human hepatocellular carcinoma. Oncogene 22(2):298-307
-
(2003)
Oncogene
, vol.22
, Issue.2
, pp. 298-307
-
-
Tsou, A.P.1
Yang, C.W.2
Huang, C.Y.3
Yu, R.C.4
Lee, Y.C.5
Chang, C.W.6
Chen, B.R.7
Chung, Y.F.8
Fann, M.J.9
Chi, C.W.10
Chiu, J.H.11
Chou, C.K.12
-
157
-
-
0036292269
-
Potential molecular marker for detecting transitional cell carcinoma
-
Chiu AW, Huang YL, Huan SK, Wang YC, Ju JP, Chen MF, Chou CK (2002) Potential molecular marker for detecting transitional cell carcinoma. Urology 60(1):181-185
-
(2002)
Urology
, vol.60
, Issue.1
, pp. 181-185
-
-
Chiu, A.W.1
Huang, Y.L.2
Huan, S.K.3
Wang, Y.C.4
Ju, J.P.5
Chen, M.F.6
Chou, C.K.7
-
158
-
-
0041805499
-
Prognostic significance of hepatoma-up-regulated protein expression in patients with urinary bladder transitional cell carcinoma
-
Huang YL, Chiu AW, Huan SK, Wang YC, Ju JP, Lu CL (2003) Prognostic significance of hepatoma-up-regulated protein expression in patients with urinary bladder transitional cell carcinoma. Anticancer Res 23(3B):2729-2733
-
(2003)
Anticancer Res
, vol.23
, Issue.3 B
, pp. 2729-2733
-
-
Huang, Y.L.1
Chiu, A.W.2
Huan, S.K.3
Wang, Y.C.4
Ju, J.P.5
Lu, C.L.6
-
159
-
-
79954527572
-
Give me a break, but not in mitosis: The mitotic DNA damage response marks DNA double-strand breaks with early signaling events
-
Giunta S, Jackson SP (2011) Give me a break, but not in mitosis: the mitotic DNA damage response marks DNA double-strand breaks with early signaling events. Cell Cycle 10(8):1215-1221
-
(2011)
Cell Cycle
, vol.10
, Issue.8
, pp. 1215-1221
-
-
Giunta, S.1
Jackson, S.P.2
-
160
-
-
77954997032
-
DNA damage signaling in response to double-strand breaks during mitosis
-
Giunta S, Belotserkovskaya R, Jackson SP (2010) DNA damage signaling in response to double-strand breaks during mitosis. J Cell Biol 190(2):197-207
-
(2010)
J Cell Biol
, vol.190
, Issue.2
, pp. 197-207
-
-
Giunta, S.1
Belotserkovskaya, R.2
Jackson, S.P.3
-
161
-
-
33750434275
-
The BRCA1/BARD1 heterodimer modulates ran-dependent mitotic spindle assembly
-
Joukov V, Groen AC, Prokhorova T, Gerson R, White E, Rodriguez A, Walter JC, Livingston DM (2006) The BRCA1/BARD1 heterodimer modulates ran-dependent mitotic spindle assembly. Cell 127(3):539-552
-
(2006)
Cell
, vol.127
, Issue.3
, pp. 539-552
-
-
Joukov, V.1
Groen, A.C.2
Prokhorova, T.3
Gerson, R.4
White, E.5
Rodriguez, A.6
Walter, J.C.7
Livingston, D.M.8
-
162
-
-
34247887536
-
Direct evidence for the role of centrosomally localized p53 in the regulation of centrosome duplication
-
Shinmura K, Bennett RA, Tarapore P, Fukasawa K (2007) Direct evidence for the role of centrosomally localized p53 in the regulation of centrosome duplication. Oncogene 26(20):2939-2944
-
(2007)
Oncogene
, vol.26
, Issue.20
, pp. 2939-2944
-
-
Shinmura, K.1
Bennett, R.A.2
Tarapore, P.3
Fukasawa, K.4
-
163
-
-
0032573068
-
BRCA1 is associated with the centrosome during mitosis
-
Hsu LC, White RL (1998) BRCA1 is associated with the centrosome during mitosis. Proc Natl Acad Sci USA 95(22):12983-12988
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, Issue.22
, pp. 12983-12988
-
-
Hsu, L.C.1
White, R.L.2
-
164
-
-
33746721468
-
Endogenous expression of phosphorylated histone H2AX in tumors in relation to DNA double-strand breaks and genomic instability
-
Yu T, MacPhail SH, Banath JP, Klokov D, Olive PL (2006) Endogenous expression of phosphorylated histone H2AX in tumors in relation to DNA double-strand breaks and genomic instability. DNA Repair (Amst) 5(8):935-946
-
(2006)
DNA Repair (Amst)
, vol.5
, Issue.8
, pp. 935-946
-
-
Yu, T.1
MacPhail, S.H.2
Banath, J.P.3
Klokov, D.4
Olive, P.L.5
-
165
-
-
84873916028
-
Gamma-H2AX expression detected by immunohistochemistry correlates with prognosis in early operable non-small cell lung cancer
-
Matthaios D, Foukas PG, Kefala M, Hountis P, Trypsianis G, Panayiotides IG, Chatzaki E, Pantelidaki E, Bouros D, Karakitsos P, Kakolyris S (2012) Gamma-H2AX expression detected by immunohistochemistry correlates with prognosis in early operable non-small cell lung cancer. Onco Targets Ther 5:309-314
-
(2012)
Onco Targets Ther
, vol.5
, pp. 309-314
-
-
Matthaios, D.1
Foukas, P.G.2
Kefala, M.3
Hountis, P.4
Trypsianis, G.5
Panayiotides, I.G.6
Chatzaki, E.7
Pantelidaki, E.8
Bouros, D.9
Karakitsos, P.10
Kakolyris, S.11
-
166
-
-
79952815581
-
Expression of gamma-H2AX in endometrial carcinomas: An immunohistochemical study with p53
-
Brunner AH, Hinterholzer S, Riss P, Heinze G, Weiss K, Brustmann H (2011) Expression of gamma-H2AX in endometrial carcinomas: an immunohistochemical study with p53. Gynecol Oncol 121(1):206-211
-
(2011)
Gynecol Oncol
, vol.121
, Issue.1
, pp. 206-211
-
-
Brunner, A.H.1
Hinterholzer, S.2
Riss, P.3
Heinze, G.4
Weiss, K.5
Brustmann, H.6
-
167
-
-
80655147072
-
Constitutive expression of gamma-H2AX has prognostic relevance in triple negative breast cancer
-
Nagelkerke A, van Kuijk SJ, Sweep FC, Nagtegaal ID, Hoogerbrugge N, Martens JW, Timmermans MA, van Laarhoven HW, Bussink J, Span PN (2011) Constitutive expression of gamma-H2AX has prognostic relevance in triple negative breast cancer. Radiother Oncol 101(1):39-45
-
(2011)
Radiother Oncol
, vol.101
, Issue.1
, pp. 39-45
-
-
Nagelkerke, A.1
Van Kuijk, S.J.2
Sweep, F.C.3
Nagtegaal, I.D.4
Hoogerbrugge, N.5
Martens, J.W.6
Timmermans, M.A.7
Van Laarhoven, H.W.8
Bussink, J.9
Span, P.N.10
-
168
-
-
33845651212
-
GammaH2AX in cancer cells: A potential biomarker for cancer diagnostics, prediction and recurrence
-
Sedelnikova OA, Bonner WM (2006) GammaH2AX in cancer cells: a potential biomarker for cancer diagnostics, prediction and recurrence. Cell Cycle 5(24):2909-2913
-
(2006)
Cell Cycle
, vol.5
, Issue.24
, pp. 2909-2913
-
-
Sedelnikova, O.A.1
Bonner, W.M.2
-
169
-
-
40449120350
-
An oncogene-induced DNA damage model for cancer development
-
Halazonetis TD, Gorgoulis VG, Bartek J (2008) An oncogene-induced DNA damage model for cancer development. Science 319(5868):1352-1355
-
(2008)
Science
, vol.319
, Issue.5868
, pp. 1352-1355
-
-
Halazonetis, T.D.1
Gorgoulis, V.G.2
Bartek, J.3
-
170
-
-
0038032023
-
Malignancy in giant cell tumor of bone
-
Bertoni F, Bacchini P, Staals EL (2003) Malignancy in giant cell tumor of bone. Cancer 97(10):2520-2529
-
(2003)
Cancer
, vol.97
, Issue.10
, pp. 2520-2529
-
-
Bertoni, F.1
Bacchini, P.2
Staals, E.L.3
-
171
-
-
33644858419
-
Giant cell tumor of bone
-
Mendenhall WM, Zlotecki RA, Scarborough MT, Gibbs CP, Mendenhall NP (2006) Giant cell tumor of bone. Am J Clin Oncol 29(1):96-99
-
(2006)
Am J Clin Oncol
, vol.29
, Issue.1
, pp. 96-99
-
-
Mendenhall, W.M.1
Zlotecki, R.A.2
Scarborough, M.T.3
Gibbs, C.P.4
Mendenhall, N.P.5
-
172
-
-
84878110677
-
Glioma pathogenesis-related protein 1 induces prostate cancer cell death through Hsc70-mediated suppression of AURKA and TPX2
-
Li L, Yang G, Ren C, Tanimoto R, Hirayama T, Wang J, Hawke D, Kim SM, Lee JS, Goltsov AA, Park S, Ittmann MM, Troncoso P, Thompson TC (2013) Glioma pathogenesis-related protein 1 induces prostate cancer cell death through Hsc70-mediated suppression of AURKA and TPX2. Mol Oncol 7(3):484-496
-
(2013)
Mol Oncol
, vol.7
, Issue.3
, pp. 484-496
-
-
Li, L.1
Yang, G.2
Ren, C.3
Tanimoto, R.4
Hirayama, T.5
Wang, J.6
Hawke, D.7
Kim, S.M.8
Lee, J.S.9
Goltsov, A.A.10
Park, S.11
Ittmann, M.M.12
Troncoso, P.13
Thompson, T.C.14
-
173
-
-
84862975903
-
High-throughput transcriptomic and RNAi analysis identifies AIM1, ERGIC1, TMED3 and TPX2 as potential drug targets in prostate cancer
-
Vainio P, Mpindi JP, Kohonen P, Fey V, Mirtti T, Alanen KA, Perala M, Kallioniemi O, Iljin K (2012) High-throughput transcriptomic and RNAi analysis identifies AIM1, ERGIC1, TMED3 and TPX2 as potential drug targets in prostate cancer. PLoS ONe 7(6):e39801
-
(2012)
PLoS ONe
, vol.7
, Issue.6
-
-
Vainio, P.1
Mpindi, J.P.2
Kohonen, P.3
Fey, V.4
Mirtti, T.5
Alanen, K.A.6
Perala, M.7
Kallioniemi, O.8
Iljin, K.9
-
174
-
-
69949167012
-
An essential role of the APKC-Aurora A-NDEL1 pathway in neurite elongation by modulation of microtubule dynamics
-
Mori D, Yamada M, Mimori-Kiyosue Y, Shirai Y, Suzuki A, Ohno S, Saya H, Wynshaw-Boris A, Hirotsune S (2009) An essential role of the APKC-Aurora A-NDEL1 pathway in neurite elongation by modulation of microtubule dynamics. Nat Cell Biol 11(9):1057-1068
-
(2009)
Nat Cell Biol
, vol.11
, Issue.9
, pp. 1057-1068
-
-
Mori, D.1
Yamada, M.2
Mimori-Kiyosue, Y.3
Shirai, Y.4
Suzuki, A.5
Ohno, S.6
Saya, H.7
Wynshaw-Boris, A.8
Hirotsune, S.9
-
175
-
-
69949135718
-
Aurora A moonlights in neurite extension
-
Lefkowitz GK, Gleeson JG (2009) Aurora A moonlights in neurite extension. Nat Cell Biol 11(9):1053-1054
-
(2009)
Nat Cell Biol
, vol.11
, Issue.9
, pp. 1053-1054
-
-
Lefkowitz, G.K.1
Gleeson, J.G.2
-
176
-
-
27544465968
-
Symmetric versus asymmetric cell division during neurogenesis in the developing vertebrate central nervous system
-
Huttner WB, Kosodo Y (2005) Symmetric versus asymmetric cell division during neurogenesis in the developing vertebrate central nervous system. Curr Opin Cell Biol 17(6):648-657
-
(2005)
Curr Opin Cell Biol
, vol.17
, Issue.6
, pp. 648-657
-
-
Huttner, W.B.1
Kosodo, Y.2
-
177
-
-
79952067750
-
Cortical progenitor expansion, self-renewal and neurogenesis - A polarized perspective
-
Fietz SA, Huttner WB (2011) Cortical progenitor expansion, self-renewal and neurogenesis - a polarized perspective. Curr Opin Neurobiol 21(1):23-35
-
(2011)
Curr Opin Neurobiol
, vol.21
, Issue.1
, pp. 23-35
-
-
Fietz, S.A.1
Huttner, W.B.2
-
178
-
-
33846460770
-
Spindle regulation in neural precursors of flies and mammals
-
Buchman JJ, Tsai LH (2007) Spindle regulation in neural precursors of flies and mammals. Nat Rev Neurosci 8(2):89-100
-
(2007)
Nat Rev Neurosci
, vol.8
, Issue.2
, pp. 89-100
-
-
Buchman, J.J.1
Tsai, L.H.2
-
179
-
-
14644404885
-
Vimentin-dependent spatial translocation of an activated MAP kinase in injured nerve
-
Perlson E, Hanz S, Ben-Yaakov K, Segal-Ruder Y, Seger R, Fainzilber M (2005) Vimentin-dependent spatial translocation of an activated MAP kinase in injured nerve. Neuron 45(5):715-726
-
(2005)
Neuron
, vol.45
, Issue.5
, pp. 715-726
-
-
Perlson, E.1
Hanz, S.2
Ben-Yaakov, K.3
Segal-Ruder, Y.4
Seger, R.5
Fainzilber, M.6
-
180
-
-
44349192028
-
Ndel1 promotes axon regeneration via intermediate filaments
-
Toth C, Shim SY, Wang J, Jiang Y, Neumayer G, Belzil C, Liu WQ, Martinez J, Zochodne D, Nguyen MD (2008) Ndel1 promotes axon regeneration via intermediate filaments. PLoS ONe 3(4):e2014
-
(2008)
PLoS ONe
, vol.3
, Issue.4
-
-
Toth, C.1
Shim, S.Y.2
Wang, J.3
Jiang, Y.4
Neumayer, G.5
Belzil, C.6
Liu, W.Q.7
Martinez, J.8
Zochodne, D.9
Nguyen, M.D.10
-
181
-
-
45549102674
-
Ndel1 controls the dyneinmediated transport of vimentin during neurite outgrowth
-
Shim SY, Samuels BA, Wang J, Neumayer G, Belzil C, Ayala R, Shi Y, Tsai LH, Nguyen MD (2008) Ndel1 controls the dyneinmediated transport of vimentin during neurite outgrowth. J Biol Chem 283(18):12232-12240
-
(2008)
J Biol Chem
, vol.283
, Issue.18
, pp. 12232-12240
-
-
Shim, S.Y.1
Samuels, B.A.2
Wang, J.3
Neumayer, G.4
Belzil, C.5
Ayala, R.6
Shi, Y.7
Tsai, L.H.8
Nguyen, M.D.9
-
182
-
-
79955595803
-
Regulation of interkinetic nuclear migration by cell cycle-coupled active and passive mechanisms in the developing brain
-
Kosodo Y, Suetsugu T, Suda M, Mimori-Kiyosue Y, Toida K, Baba SA, Kimura A, Matsuzaki F (2011) Regulation of interkinetic nuclear migration by cell cycle-coupled active and passive mechanisms in the developing brain. EMBO J 30(9):1690-1704
-
(2011)
EMBO J
, vol.30
, Issue.9
, pp. 1690-1704
-
-
Kosodo, Y.1
Suetsugu, T.2
Suda, M.3
Mimori-Kiyosue, Y.4
Toida, K.5
Baba, S.A.6
Kimura, A.7
Matsuzaki, F.8
-
183
-
-
79955593510
-
Interkinetic nuclear migration: Cell cycle on the move
-
Del Bene F (2011) Interkinetic nuclear migration: cell cycle on the move. EMBO J 30(9):1676-1677
-
(2011)
EMBO J
, vol.30
, Issue.9
, pp. 1676-1677
-
-
Del Bene, F.1
-
185
-
-
0003880161
-
-
4th edn. Garland, New York
-
Alberts B, Johnson A, Lewis J, Raff M, Roberts K, Walter P (2002) Molecular biology of the cell, 4th edn. Garland, New York, pp 984-986
-
(2002)
Molecular Biology of the Cell
, pp. 984-986
-
-
Alberts, B.1
Johnson, A.2
Lewis, J.3
Raff, M.4
Roberts, K.5
Walter, P.6
-
186
-
-
0030801002
-
Gapped BLAST and PSI-BLAST: A new generation of protein database search programs
-
Altschul SF, Madden TL, Schaffer AA, Zhang J, Zhang Z, Miller W, Lipman DJ (1997) Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Res 25(17):3389-3402
-
(1997)
Nucleic Acids Res
, vol.25
, Issue.17
, pp. 3389-3402
-
-
Altschul, S.F.1
Madden, T.L.2
Schaffer, A.A.3
Zhang, J.4
Zhang, Z.5
Miller, W.6
Lipman, D.J.7
-
187
-
-
27144489108
-
Protein database searches using compositionally adjusted substitution matrices
-
Altschul SF, Wootton JC, Gertz EM, Agarwala R, Morgulis A, Schaffer AA, Yu YK (2005) Protein database searches using compositionally adjusted substitution matrices. FEBS J 272(20):5101-5109
-
(2005)
FEBS J
, vol.272
, Issue.20
, pp. 5101-5109
-
-
Altschul, S.F.1
Wootton, J.C.2
Gertz, E.M.3
Agarwala, R.4
Morgulis, A.5
Schaffer, A.A.6
Yu, Y.K.7
-
188
-
-
67649442528
-
Overexpression of the receptor for hyaluronan-mediated motility, correlates with expression of microtubule-associated protein in human oral squamous cell carcinomas
-
Shigeishi H, Fujimoto S, Hiraoka M, Ono S, Taki M, Ohta K, Higashikawa K, Kamata N (2009) Overexpression of the receptor for hyaluronan-mediated motility, correlates with expression of microtubule-associated protein in human oral squamous cell carcinomas. Int J Oncol 34(6):1565-1571
-
(2009)
Int J Oncol
, vol.34
, Issue.6
, pp. 1565-1571
-
-
Shigeishi, H.1
Fujimoto, S.2
Hiraoka, M.3
Ono, S.4
Taki, M.5
Ohta, K.6
Higashikawa, K.7
Kamata, N.8
-
189
-
-
29144480125
-
Restricted-expressed proliferation-associated Protein (Repp86) expression in squamous cell carcinoma of the oral cavity
-
Fenner M, Wehrhan F, Jehle M, Amann K, Radespiel-Troger M, Grabenbauer G, Zenk J, Nkenke E, Schinhammer M, Schultze-Mosgau S (2005) Restricted-expressed proliferation-associated Protein (Repp86) expression in squamous cell carcinoma of the oral cavity. Strahlenther Onkol 181(12):755-761
-
(2005)
Strahlenther Onkol
, vol.181
, Issue.12
, pp. 755-761
-
-
Fenner, M.1
Wehrhan, F.2
Jehle, M.3
Amann, K.4
Radespiel-Troger, M.5
Grabenbauer, G.6
Zenk, J.7
Nkenke, E.8
Schinhammer, M.9
Schultze-Mosgau, S.10
-
190
-
-
78650678164
-
Identification of gene markers associated with aggressive meningioma by filtering across multiple sets of gene expression arrays
-
Stuart JE, Lusis EA, Scheck AC, Coons SW, Lal A, Perry A, Gutmann DH (2011) Identification of gene markers associated with aggressive meningioma by filtering across multiple sets of gene expression arrays. J Neuropathol exp Neurol 70(1):1-12
-
(2011)
J Neuropathol Exp Neurol
, vol.70
, Issue.1
, pp. 1-12
-
-
Stuart, J.E.1
Lusis, E.A.2
Scheck, A.C.3
Coons, S.W.4
Lal, A.5
Perry, A.6
Gutmann, D.H.7
-
191
-
-
33744725976
-
Expression and clinical significance of hepatocellular cancer antigen genes in human hepatocellular carcinoma
-
Wang WX, Leng XS, Peng JR, Mu DC, Wang Y, Zhu JY, Du RY, Chen WF (2003) Expression and clinical significance of hepatocellular cancer antigen genes in human hepatocellular carcinoma. Zhonghua Wai Ke Za Zhi 41(7):506-508
-
(2003)
Zhonghua Wai Ke za Zhi
, vol.41
, Issue.7
, pp. 506-508
-
-
Wang, W.X.1
Leng, X.S.2
Peng, J.R.3
Mu, D.C.4
Wang, Y.5
Zhu, J.Y.6
Du, R.Y.7
Chen, W.F.8
-
192
-
-
84887611002
-
Upregulation of the TPX2 gene is associated with enhanced tumor malignance of esophageal squamous cell carcinoma
-
Liu HC, Zhang Y, Wang XL, Qin WS, Liu YH, Zhang L, Zhu CL (2013) Upregulation of the TPX2 gene is associated with enhanced tumor malignance of esophageal squamous cell carcinoma. Biomed Pharmacother 67(8):751-755
-
(2013)
Biomed Pharmacother
, vol.67
, Issue.8
, pp. 751-755
-
-
Liu, H.C.1
Zhang, Y.2
Wang, X.L.3
Qin, W.S.4
Liu, Y.H.5
Zhang, L.6
Zhu, C.L.7
-
193
-
-
84905716891
-
TPX2 expression is associated with cell proliferation and patient outcome in esophageal squamous cell carcinoma
-
[epub ahead of print]
-
Hsu PK, Chen HY, Yeh YC, Yen CC, Wu YC, Hsu CP, Hsu WH, Chou TY (2013) TPX2 expression is associated with cell proliferation and patient outcome in esophageal squamous cell carcinoma. J Gastroenterol [epub ahead of print]
-
(2013)
J Gastroenterol
-
-
Hsu, P.K.1
Chen, H.Y.2
Yeh, Y.C.3
Yen, C.C.4
Wu, Y.C.5
Hsu, C.P.6
Hsu, W.H.7
Chou, T.Y.8
-
194
-
-
62849128428
-
Expression of TPX2 in salivary gland carcinomas
-
Shigeishi H, Ohta K, Hiraoka M, Fujimoto S, Minami M, Higashikawa K, Kamata N (2009) Expression of TPX2 in salivary gland carcinomas. Oncol Rep 21(2):341-344
-
(2009)
Oncol Rep
, vol.21
, Issue.2
, pp. 341-344
-
-
Shigeishi, H.1
Ohta, K.2
Hiraoka, M.3
Fujimoto, S.4
Minami, M.5
Higashikawa, K.6
Kamata, N.7
-
195
-
-
0032797062
-
Prognostic significance of a novel proliferation marker, anti-repp 86, for endometrial carcinoma: A multivariate study
-
Bonatz G, Luttges J, Hedderich J, Inform D, Jonat W, Rudolph P, Parwaresch R (1999) Prognostic significance of a novel proliferation marker, anti-repp 86, for endometrial carcinoma: a multivariate study. Hum Pathol 30(8):949-956
-
(1999)
Hum Pathol
, vol.30
, Issue.8
, pp. 949-956
-
-
Bonatz, G.1
Luttges, J.2
Hedderich, J.3
Inform, D.4
Jonat, W.5
Rudolph, P.6
Parwaresch, R.7
-
196
-
-
58149496571
-
Aurora kinase inhibitors synergize with paclitaxel to induce apoptosis in ovarian cancer cells
-
Scharer CD, Laycock N, Osunkoya AO, Logani S, McDonald JF, Benigno BB, Moreno CS (2008) Aurora kinase inhibitors synergize with paclitaxel to induce apoptosis in ovarian cancer cells. J Transl Med 6:79
-
(2008)
J Transl Med
, vol.6
, pp. 79
-
-
Scharer, C.D.1
Laycock, N.2
Osunkoya, A.O.3
Logani, S.4
McDonald, J.F.5
Benigno, B.B.6
Moreno, C.S.7
-
197
-
-
77951117397
-
Identification of gene signatures and molecular markers for human lung cancer prognosis using an in vitro lung carcinogenesis system
-
Kadara H, Lacroix L, Behrens C, Solis L, Gu X, Lee JJ, Tahara E, Lotan D, Hong WK, Wistuba II, Lotan R (2009) Identification of gene signatures and molecular markers for human lung cancer prognosis using an in vitro lung carcinogenesis system. Cancer Prev Res (Phila) 2(8):702-711
-
(2009)
Cancer Prev Res (Phila)
, vol.2
, Issue.8
, pp. 702-711
-
-
Kadara, H.1
Lacroix, L.2
Behrens, C.3
Solis, L.4
Gu, X.5
Lee, J.J.6
Tahara, E.7
Lotan, D.8
Hong, W.K.9
Wistuba, I.I.10
Lotan, R.11
-
198
-
-
41749115743
-
The diagnostic value of Ki-67 and repp86 in distinguishing between benign and malignant mesothelial proliferations
-
Taheri ZM, Mehrafza M, Mohammadi F, Khoddami M, Bahadori M, Masjedi MR (2008) The diagnostic value of Ki-67 and repp86 in distinguishing between benign and malignant mesothelial proliferations. Arch Pathol Lab Med 132(4):694-697
-
(2008)
Arch Pathol Lab Med
, vol.132
, Issue.4
, pp. 694-697
-
-
Taheri, Z.M.1
Mehrafza, M.2
Mohammadi, F.3
Khoddami, M.4
Bahadori, M.5
Masjedi, M.R.6
-
199
-
-
0038134992
-
Repp86 expression and outcome in patients with neuroblastoma
-
Krams M, Heidebrecht HJ, Hero B, Berthold F, Harms D, Parwaresch R, Rudolph P (2003) Repp86 expression and outcome in patients with neuroblastoma. J Clin Oncol 21(9):1810-1818
-
(2003)
J Clin Oncol
, vol.21
, Issue.9
, pp. 1810-1818
-
-
Krams, M.1
Heidebrecht, H.J.2
Hero, B.3
Berthold, F.4
Harms, D.5
Parwaresch, R.6
Rudolph, P.7
|