-
1
-
-
4744366279
-
Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer
-
DOI 10.1056/NEJMoa040720
-
Tannock, I. F., de Wit, R., Berry, W. R., et al. (2004). Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer. The New England Journal of Medicine, 351(15), 1502-1512. (Pubitemid 39315317)
-
(2004)
New England Journal of Medicine
, vol.351
, Issue.15
, pp. 1502-1512
-
-
Tannock, I.F.1
De Wit, R.2
Berry, W.R.3
Horti, J.4
Pluzanska, A.5
Chi, K.N.6
Oudard, S.7
Theodore, C.8
James, N.D.9
Turesson, I.10
Rosenthal, M.A.11
Eisenberger, M.A.12
-
2
-
-
77955066199
-
Sipuleucel-T immunotherapy for castration-resistant prostate cancer
-
Kantoff, P. W., Higano, C. S., Shore, N. D., et al. (2010). Sipuleucel-T immunotherapy for castration-resistant prostate cancer. The New England Journal of Medicine, 363(5), 411-422.
-
(2010)
The New England Journal of Medicine
, vol.363
, Issue.5
, pp. 411-422
-
-
Kantoff, P.W.1
Higano, C.S.2
Shore, N.D.3
-
3
-
-
77957682309
-
Prednisone plus cabazitaxel or mitoxantrone for metastatic castration-resistant prostate cancer progressing after docetaxel treatment: A randomised open-label trial
-
de Bono, J. S., Oudard, S., Ozguroglu, M., et al. (2010). Prednisone plus cabazitaxel or mitoxantrone for metastatic castration-resistant prostate cancer progressing after docetaxel treatment: a randomised open-label trial. The Lancet, 376(9747), 1147-1154.
-
(2010)
The Lancet
, vol.376
, Issue.9747
, pp. 1147-1154
-
-
De Bono, J.S.1
Oudard, S.2
Ozguroglu, M.3
-
4
-
-
84880428467
-
Alpha emitter radium-223 and survival in metastatic prostate cancer
-
Parker, C., Nilsson, S., Heinrich, D., et al. (2013). Alpha emitter radium-223 and survival in metastatic prostate cancer. The New England Journal of Medicine, 369(3), 213-223.
-
(2013)
The New England Journal of Medicine
, vol.369
, Issue.3
, pp. 213-223
-
-
Parker, C.1
Nilsson, S.2
Heinrich, D.3
-
5
-
-
84866948935
-
Abiraterone acetate for treatment of metastatic castration-resistant prostate cancer: Final overall survival analysis of the COU-AA-301 randomised, double-blind, placebo-controlled phase 3 study
-
Fizazi, K., Scher, H. I., Molina, A., et al. (2012). Abiraterone acetate for treatment of metastatic castration-resistant prostate cancer: final overall survival analysis of the COU-AA-301 randomised, double-blind, placebo-controlled phase 3 study. The Lancet Oncology, 13, 983-992.
-
(2012)
The Lancet Oncology
, vol.13
, pp. 983-992
-
-
Fizazi, K.1
Scher, H.I.2
Molina, A.3
-
6
-
-
84858114087
-
Effect of MDV3100, an androgen receptor signaling inhibitor (ARSI), on overall survival in patients with prostate cancer postdocetaxel: Results from the phase III AFFIRM study
-
Scher, H. I., Fizazi, K., Saad, F., et al. (2012). Effect of MDV3100, an androgen receptor signaling inhibitor (ARSI), on overall survival in patients with prostate cancer postdocetaxel: results from the phase III AFFIRM study. Journal of Clinical Oncology, 30(Suppl 5), 1.
-
(2012)
Journal of Clinical Oncology
, vol.30
, Issue.SUPPL. 5
, pp. 1
-
-
Scher, H.I.1
Fizazi, K.2
Saad, F.3
-
7
-
-
50549121134
-
The distribution of secondary growths in cancer of the breast
-
Paget, S. (1889). The distribution of secondary growths in cancer of the breast. The Lancet, 133(3421), 571-573.
-
(1889)
The Lancet
, vol.133
, Issue.3421
, pp. 571-573
-
-
Paget, S.1
-
8
-
-
0033304730
-
Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand families
-
Suda, T., Takahashi, N., Udagawa, N., Jimi, E., Gillespie, M. T., & Martin, T. J. (1999). Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand families. Endocrine Reviews, 20(3), 345-357. (Pubitemid 30649812)
-
(1999)
Endocrine Reviews
, vol.20
, Issue.3
, pp. 345-357
-
-
Suda, T.1
Takahashi, N.2
Udagawa, N.3
Jimi, E.4
Gillespie, M.T.5
Martin, T.J.6
-
9
-
-
30644469500
-
RANKL-RANK signaling in osteoclastogenesis and bone disease
-
DOI 10.1016/j.molmed.2005.11.007, PII S1471491405002674
-
Wada, T., Nakashima, T., Hiroshi, N., & Penninger, J. M. (2006). RANKL-RANK signaling in osteoclastogenesis and bone disease. Trends in Molecular Medicine, 12(1), 17-25. (Pubitemid 43089652)
-
(2006)
Trends in Molecular Medicine
, vol.12
, Issue.1
, pp. 17-25
-
-
Wada, T.1
Nakashima, T.2
Hiroshi, N.3
Penninger, J.M.4
-
10
-
-
79953331206
-
Human prostate cancer metastases target the hematopoietic stem cell niche to establish footholds in mouse bone marrow
-
Shiozawa, Y., Pedersen, E. A., Havens, A. M., et al. (2011). Human prostate cancer metastases target the hematopoietic stem cell niche to establish footholds in mouse bone marrow. The Journal of Clinical Investigation, 121(4), 1298.
-
(2011)
The Journal of Clinical Investigation
, vol.121
, Issue.4
, pp. 1298
-
-
Shiozawa, Y.1
Pedersen, E.A.2
Havens, A.M.3
-
11
-
-
84860851484
-
The prostate cancer bone marrow niche: More than just 'fertile soil'
-
Pedersen, E. A., Shiozawa, Y., Pienta, K. J., & Taichman, R. S. (2012). The prostate cancer bone marrow niche: more than just 'fertile soil'. Asian Journal of Andrology, 14(3), 423-427.
-
(2012)
Asian Journal of Andrology
, vol.14
, Issue.3
, pp. 423-427
-
-
Pedersen, E.A.1
Shiozawa, Y.2
Pienta, K.J.3
Taichman, R.S.4
-
12
-
-
15444365985
-
Bone turnover mediates preferential localization of prostate cancer in the skeleton
-
DOI 10.1210/en.2004-1211
-
Schneider, A., Kalikin, L. M., Mattos, A. C., et al. (2005). Bone turnover mediates preferential localization of prostate cancer in the skeleton. Endocrinology, 146(4), 1727-1736. (Pubitemid 40396881)
-
(2005)
Endocrinology
, vol.146
, Issue.4
, pp. 1727-1736
-
-
Schneider, A.1
Kalikin, L.M.2
Mattos, A.C.3
Keller, E.T.4
Allen, M.J.5
Pienta, K.J.6
McCauley, L.K.7
-
13
-
-
76749109371
-
GAS6/AXL axis regulates prostate cancer invasion, proliferation, and survival in the bone marrow niche
-
Shiozawa, Y., Pedersen, E. A., Patel, L. R., et al. (2010). GAS6/AXL axis regulates prostate cancer invasion, proliferation, and survival in the bone marrow niche. Neoplasia (New York, NY), 12(2), 116.
-
(2010)
Neoplasia (New York, NY)
, vol.12
, Issue.2
, pp. 116
-
-
Shiozawa, Y.1
Pedersen, E.A.2
Patel, L.R.3
-
14
-
-
84876545834
-
GAS6 receptor status is associated with dormancy and bone metastatic tumor formation
-
Taichman, R. S., Patel, L. R., Bedenis, R., et al. (2013). GAS6 receptor status is associated with dormancy and bone metastatic tumor formation. PloS one, 8(4), e61873.
-
(2013)
PloS One
, vol.8
, Issue.4
-
-
Taichman, R.S.1
Patel, L.R.2
Bedenis, R.3
-
15
-
-
27144441519
-
A paradigm for the treatment of prostate cancer bone metastases based on an understanding of tumor cell-microenvironment interactions
-
DOI 10.1002/jcb.20522
-
Loberg, R. D., Gayed, B. A., Olson, K. B., & Pienta, K. J. (2005). A paradigm for the treatment of prostate cancer bone metastases based on an understanding of tumor cell-microenvironment interactions. Journal of Cellular Biochemistry, 96(3), 439-446. (Pubitemid 41504643)
-
(2005)
Journal of Cellular Biochemistry
, vol.96
, Issue.3
, pp. 439-446
-
-
Loberg, R.D.1
Gayed, B.A.2
Olson, K.B.3
Pienta, K.J.4
-
16
-
-
33750738067
-
Basic mechanisms responsible for osteolytic and osteoblastic bone metastases
-
DOI 10.1158/1078-0432.CCR-06-1007
-
Guise, T. A., Mohammad, K. S., Clines, G., et al. (2006). Basic mechanisms responsible for osteolytic and osteoblastic bone metastases. Clinical cancer research, 12(20), 6213s-6216s. (Pubitemid 44703792)
-
(2006)
Clinical Cancer Research
, vol.12
, Issue.20 PART 2
-
-
Guise, T.A.1
Mohammad, K.S.2
Clines, G.3
Stebbins, E.G.4
Wong, D.H.5
Higgins, L.S.6
Vessella, R.7
Corey, E.8
Padalecki, S.9
Suva, L.10
Chirgwin, J.M.11
Pearse12
Roodman13
Lipton14
Clohisy15
Weilbaecher16
Smith17
-
17
-
-
0642337996
-
Combined analysis of two multicenter, randomized, placebo-controlled studies of pamidronate disodium for the palliation of bone pain in men with metastatic prostate cancer
-
DOI 10.1200/JCO.2003.05.147
-
Small, E. J., Smith, M. R., Seaman, J. J., Petrone, S., & Kowalski, M. O. (2003). Combined analysis of two multicenter, randomized, placebo-controlled studies of pamidronate disodium for the palliation of bone pain in men with metastatic prostate cancer. Journal of Clinical Oncology, 21(23), 4277-4284. (Pubitemid 46621802)
-
(2003)
Journal of Clinical Oncology
, vol.21
, Issue.23
, pp. 4277-4284
-
-
Small, E.J.1
Smith, M.R.2
Seaman, J.J.3
Petrone, S.4
Kowalski, M.O.5
-
18
-
-
2942518111
-
Long-term efficacy of zoledronic acid for the prevention of skeletal complications in patients with metastatic hormone-refractory prostate cancer
-
Saad, F., Gleason, D. M., Murray, R., et al. (2004). Long-term efficacy of zoledronic acid for the prevention of skeletal complications in patients with metastatic hormone-refractory prostate cancer. Journal of the National Cancer Institute, 96(11), 879-882. (Pubitemid 38807610)
-
(2004)
Journal of the National Cancer Institute
, vol.96
, Issue.11
, pp. 879-882
-
-
Saad, F.1
Gleason, D.M.2
Murray, R.3
Tchekmedyian, S.4
Venner, P.5
Lacombe, L.6
Chin, J.L.7
Vinholes, J.J.8
Goas, J.A.9
Zheng, M.10
-
19
-
-
10744233021
-
Long-term efficacy and safety of zoledronic acid compared with pamidronate disodium in the treatment of skeletal complications in patients with advanced multiple myeloma or breast carcinoma: A randomized, double-blind, multicenter, comparative trial
-
DOI 10.1002/cncr.11701
-
Rosen, L. S., Gordon, D., Kaminski, M., et al. (2003). Long-term efficacy and safety of zoledronic acid compared with pamidronate disodium in the treatment of skeletal complications in patients with advanced multiple myeloma or breast carcinoma. Cancer, 98(8), 1735-1744. (Pubitemid 37238631)
-
(2003)
Cancer
, vol.98
, Issue.8
, pp. 1735-1744
-
-
Rosen, L.S.1
Gordon, D.2
Kaminski, M.3
Howell, A.4
Belch, A.5
Mackey, J.6
Apffelstaedt, J.7
Hussein, M.A.8
Coleman, R.E.9
Reitsma, D.J.10
Chen, B.-L.11
Seaman, J.J.12
-
20
-
-
84905088310
-
Efficacy and safety of zoledronic acid in men with castration-sensitive prostate cancer and bone metastases: Results of CALGB 90202 (alliance)
-
Smith, M. R., Halabi, S., Ryan, C. J., et al. (2013). Efficacy and safety of zoledronic acid in men with castration-sensitive prostate cancer and bone metastases: results of CALGB 90202 (alliance). ASCO Meeting Abstracts, 31(6-suppl), 27.
-
(2013)
ASCO Meeting Abstracts
, vol.31
, Issue.6 SUPPL.
, pp. 27
-
-
Smith, M.R.1
Halabi, S.2
Ryan, C.J.3
-
21
-
-
84905109952
-
Zoledronic acid for the prevention of bone metastases in high risk prostate cancer patients. A randomised, open label, multicentre study of the European Association of Urology (EAU) in cooperation with the Scandinavian Prostate Cancer Group (SPCG) and the Arbeitsgemeinschaft Urologische Onkologie (AUO)
-
Wirth, M., Tammela, T., Huland, H., et al. (2008). Zoledronic acid for the prevention of bone metastases in high risk prostate cancer patients. A randomised, open label, multicentre study of the European Association of Urology (EAU) in cooperation with the Scandinavian Prostate Cancer Group (SPCG) and the Arbeitsgemeinschaft Urologische Onkologie (AUO). European Urology Supplements, 7(3), 232.
-
(2008)
European Urology Supplements
, vol.7
, Issue.3
, pp. 232
-
-
Wirth, M.1
Tammela, T.2
Huland, H.3
-
22
-
-
69049105440
-
Denosumab in men receiving androgen-deprivation therapy for prostate cancer
-
Smith, M. R., Egerdie, B., Toriz, N. H., et al. (2009). Denosumab in men receiving androgen-deprivation therapy for prostate cancer. The New England Journal of Medicine, 361(8), 745-755.
-
(2009)
The New England Journal of Medicine
, vol.361
, Issue.8
, pp. 745-755
-
-
Smith, M.R.1
Egerdie, B.2
Toriz, N.H.3
-
23
-
-
63749094012
-
Randomized phase II trial of denosumab in patients with bone metastases from prostate cancer, breast cancer, or other neoplasms after intravenous bisphosphonates
-
Fizazi, K., Lipton, A., Mariette, X., et al. (2009). Randomized phase II trial of denosumab in patients with bone metastases from prostate cancer, breast cancer, or other neoplasms after intravenous bisphosphonates. Journal of Clinical Oncology, 27(10), 1564-1571.
-
(2009)
Journal of Clinical Oncology
, vol.27
, Issue.10
, pp. 1564-1571
-
-
Fizazi, K.1
Lipton, A.2
Mariette, X.3
-
24
-
-
79952360832
-
Denosumab versus zoledronic acid for treatment of bone metastases in men with castration-resistant prostate cancer: A randomised, double-blind study
-
Fizazi, K., Carducci, M., Smith, M., et al. (2011). Denosumab versus zoledronic acid for treatment of bone metastases in men with castration-resistant prostate cancer: a randomised, double-blind study. The Lancet, 377(9768), 813-822.
-
(2011)
The Lancet
, vol.377
, Issue.9768
, pp. 813-822
-
-
Fizazi, K.1
Carducci, M.2
Smith, M.3
-
25
-
-
84855516339
-
Denosumab and bone-metastasis-free survival in men with castration-resistant prostate cancer: Results of a phase 3, randomised, placebo-controlled trial
-
Smith, M. R., Saad, F., Coleman, R., et al. (2012). Denosumab and bone-metastasis-free survival in men with castration-resistant prostate cancer: results of a phase 3, randomised, placebo-controlled trial. The Lancet, 379(9810), 39-46.
-
(2012)
The Lancet
, vol.379
, Issue.9810
, pp. 39-46
-
-
Smith, M.R.1
Saad, F.2
Coleman, R.3
-
27
-
-
0029972407
-
Dosage and response in radiopharmaceutical therapy of painful osseous metastases
-
Silberstein, E. B. (1996). Dosage and response in radiopharmaceutical therapy of painful osseous metastases. Journal of Nuclear Medicine, 37(2), 249-252.
-
(1996)
Journal of Nuclear Medicine
, vol.37
, Issue.2
, pp. 249-252
-
-
Silberstein, E.B.1
-
28
-
-
0035798930
-
Bone-targeted therapy for advanced androgen-independent carcinoma of the prostate: A randomised phase II trial
-
DOI 10.1016/S0140-6736(00)03639-4
-
Tu, S., Millikan, R. E., Mengistu, B., et al. (2001). Bone-targeted therapy for advanced androgen-independent carcinoma of the prostate: a randomised phase II trial. The Lancet, 357(9253), 336-341. (Pubitemid 32128538)
-
(2001)
Lancet
, vol.357
, Issue.9253
, pp. 336-341
-
-
Tu, S.-M.1
Millikan, R.E.2
Mengistu, B.3
Delpassand, E.S.4
Amato, R.J.5
Pagliaro, L.C.6
Daliani, D.7
Papandreou, C.N.8
Smith, T.L.9
Kim, J.10
Podoloff, D.A.11
Logothetis, C.J.12
-
29
-
-
33846703339
-
Safety and efficacy of repeat administration of samarium Sm-153 lexidronam to patients with metastatic bone pain
-
DOI 10.1002/cncr.22431
-
Sartor, O., Reid, R. H., Bushnell, D. L., Quick, D. P., & Ell, P. J. (2007). Safety and efficacy of repeat administration of samarium Sm-153 lexidronam to patients with metastatic bone pain. Cancer, 109(3), 637-643. (Pubitemid 46190974)
-
(2007)
Cancer
, vol.109
, Issue.3
, pp. 637-643
-
-
Sartor, O.1
Reid, R.H.2
Bushnell, D.L.3
Quick, D.P.4
Ell, P.J.5
-
30
-
-
66349089867
-
Phase II trial of consolidation docetaxel and samarium-153 in patients with bone metastases from castration-resistant prostate cancer
-
Fizazi, K., Beuzeboc, P., Lumbroso, J., et al. (2009). Phase II trial of consolidation docetaxel and samarium-153 in patients with bone metastases from castration-resistant prostate cancer. Journal of Clinical Oncology, 27(15), 2429-2435.
-
(2009)
Journal of Clinical Oncology
, vol.27
, Issue.15
, pp. 2429-2435
-
-
Fizazi, K.1
Beuzeboc, P.2
Lumbroso, J.3
-
31
-
-
84892633157
-
Clinical outcomes in patients with castrate-refractory prostate cancer (CRPC) metastatic to bone randomized in the factorial TRAPEZE trial to docetaxel (D) with strontium-89 (Sr89), zoledronic acid (ZA), neither, or both (ISRCTN 12808747)
-
James, N. D., Pirrie, S., Barton, D., et al. (2013). Clinical outcomes in patients with castrate-refractory prostate cancer (CRPC) metastatic to bone randomized in the factorial TRAPEZE trial to docetaxel (D) with strontium-89 (Sr89), zoledronic acid (ZA), neither, or both (ISRCTN 12808747). ASCO Meeting Abstracts, 31(18-suppl), LBA5000.
-
(2013)
ASCO Meeting Abstracts
, vol.31
, Issue.18 SUPPL.
-
-
James, N.D.1
Pirrie, S.2
Barton, D.3
-
32
-
-
34347244905
-
Bone-targeted radium-223 in symptomatic, hormone-refractory prostate cancer: A randomised, multicentre, placebo-controlled phase II study
-
DOI 10.1016/S1470-2045(07)70147-X, PII S147020450770147X
-
Nilsson, S., Franzén, L., Parker, C., et al. (2007). Bone-targeted radium-223 in symptomatic, hormone-refractory prostate cancer: a randomised, multicentre, placebo-controlled phase II study. The Lancet Oncology, 8(7), 587-594. (Pubitemid 46995621)
-
(2007)
Lancet Oncology
, vol.8
, Issue.7
, pp. 587-594
-
-
Nilsson, S.1
Franzen, L.2
Parker, C.3
Tyrrell, C.4
Blom, R.5
Tennvall, J.6
Lennernas, B.7
Petersson, U.8
Johannessen, D.C.9
Sokal, M.10
Pigott, K.11
Yachnin, J.12
Garkavij, M.13
Strang, P.14
Harmenberg, J.15
Bolstad, B.16
Bruland, O.S.17
-
33
-
-
84858706749
-
A randomized, dose-response, multicenter phase II study of radium-223 chloride for the palliation of painful bone metastases in patients with castration-resistant prostate cancer
-
Nilsson, S., Strang, P., Aksnes, A. K., et al. (2012). A randomized, dose-response, multicenter phase II study of radium-223 chloride for the palliation of painful bone metastases in patients with castration-resistant prostate cancer. European Journal of Cancer, 48(5), 678-686.
-
(2012)
European Journal of Cancer
, vol.48
, Issue.5
, pp. 678-686
-
-
Nilsson, S.1
Strang, P.2
Aksnes, A.K.3
-
34
-
-
84900503061
-
Safety of radium-223 dichloride (ra-223) with docetaxel (D) in patients with bone metastases from castration-resistant prostate cancer (CRPC): A phase I prostate cancer clinical trials consortium study
-
Morris, M. J., Hammers, H. J., Sweeney, C., et al. (2013). Safety of radium-223 dichloride (ra-223) with docetaxel (D) in patients with bone metastases from castration-resistant prostate cancer (CRPC): a phase I prostate cancer clinical trials consortium study. ASCO Meeting Abstracts, 31(15-suppl), 5021.
-
(2013)
ASCO Meeting Abstracts
, vol.31
, Issue.15 SUPPL.
, pp. 5021
-
-
Morris, M.J.1
Hammers, H.J.2
Sweeney, C.3
-
35
-
-
0037441843
-
Effect of endothelin-A receptor blockade with atrasentan on tumor progression in men with hormone-refractory prostate cancer: A randomized, phase II, placebo-controlled trial
-
DOI 10.1200/JCO.2003.04.176
-
Carducci, M. A., Padley, R. J., Breul, J., et al. (2003). Effect of endothelin-A receptor blockade with atrasentan on tumor progression inmen with hormone-refractory prostate cancer: a randomized, phase II, placebo-controlled trial. Journal of Clinical Oncology, 21(4), 679-689. (Pubitemid 46621903)
-
(2003)
Journal of Clinical Oncology
, vol.21
, Issue.4
, pp. 679-689
-
-
Carducci, M.A.1
Padley, R.J.2
Breul, J.3
Vogelzang, N.J.4
Zonnenberg, B.A.5
Daliani, D.D.6
Schulman, C.C.7
Nabulsi, A.A.8
Humerickhouse, R.A.9
Weinberg, M.A.10
Schmitt, J.L.11
Nelson, J.B.12
-
36
-
-
79151468942
-
A phase I study of zibotentan (ZD4054) in patients with metastatic, castrate-resistant prostate cancer
-
Schelman, W. R., Liu, G., Wilding, G., Morris, T., Phung, D., & Dreicer, R. (2011). A phase I study of zibotentan (ZD4054) in patients with metastatic, castrate-resistant prostate cancer. Investigational New Drugs, 29(1), 118-125.
-
(2011)
Investigational New Drugs
, vol.29
, Issue.1
, pp. 118-125
-
-
Schelman, W.R.1
Liu, G.2
Wilding, G.3
Morris, T.4
Phung, D.5
Dreicer, R.6
-
37
-
-
77956634017
-
Final safety and efficacy analysis of the specific endothelin A receptor antagonist zibotentan (ZD4054) in patients with metastatic castration-resistant prostate cancer and bone metastases who were pain-free or mildly symptomatic for pain: A double-blind, placebo-controlled, randomized phase II trial
-
James, N. D., Caty, A., Payne, H., et al. (2010). Final safety and efficacy analysis of the specific endothelin A receptor antagonist zibotentan (ZD4054) in patients with metastatic castration-resistant prostate cancer and bone metastases who were pain-free or mildly symptomatic for pain: a double-blind, placebo-controlled, randomized phase II trial. BJU International, 106(7), 966-973.
-
(2010)
BJU International
, vol.106
, Issue.7
, pp. 966-973
-
-
James, N.D.1
Caty, A.2
Payne, H.3
-
38
-
-
55549112219
-
Phase 3, randomized, controlled trial of atrasentan in patients with nonmetastatic, hormone-refractory prostate cancer
-
Nelson, J. B., Love, W., Chin, J. L., et al. (2008). Phase 3, randomized, controlled trial of atrasentan in patients with nonmetastatic, hormone-refractory prostate cancer. Cancer, 113(9), 2478-2487.
-
(2008)
Cancer
, vol.113
, Issue.9
, pp. 2478-2487
-
-
Nelson, J.B.1
Love, W.2
Chin, J.L.3
-
39
-
-
84868200731
-
Phase 3, randomized, placebo-controlled study of zibotentan (ZD4054) in patients with castration-resistant prostate cancer metastatic to bone
-
Nelson, J. B., Fizazi, K., Miller, K., et al. (2012). Phase 3, randomized, placebo-controlled study of zibotentan (ZD4054) in patients with castration-resistant prostate cancer metastatic to bone. Cancer, 118(22), 5709-5718.
-
(2012)
Cancer
, vol.118
, Issue.22
, pp. 5709-5718
-
-
Nelson, J.B.1
Fizazi, K.2
Miller, K.3
-
40
-
-
84882450996
-
Phase III, randomized, placebo-controlled study of once-daily oral zibotentan (ZD4054) in patients with non-metastatic castration-resistant prostate cancer
-
Miller, K., Moul, J., Gleave, M., et al. (2013). Phase III, randomized, placebo-controlled study of once-daily oral zibotentan (ZD4054) in patients with non-metastatic castration-resistant prostate cancer. Prostate cancer and prostatic diseases, 16(2), 187-192.
-
(2013)
Prostate Cancer and Prostatic Diseases
, vol.16
, Issue.2
, pp. 187-192
-
-
Miller, K.1
Moul, J.2
Gleave, M.3
-
41
-
-
33749045722
-
Endothelin receptor A blockade enhances taxane effects in prostate cancer
-
DOI 10.1593/neo.06388
-
Akhavan, A., McHugh, K. H., Guruli, G., et al. (2006). Endothelin receptor A blockade enhances taxane effects in prostate cancer. Neoplasia, 8(9), 725-732. (Pubitemid 44465524)
-
(2006)
Neoplasia
, vol.8
, Issue.9
, pp. 725-732
-
-
Akhavan, A.1
McHugh, K.H.2
Guruli, G.3
Bies, R.R.4
Zamboni, W.C.5
Strychor, S.6
Nelson, J.B.7
Pflug, B.R.8
-
42
-
-
70349758510
-
Src kinases as therapeutic targets for cancer
-
Kim, L. C., Song, L., & Haura, E. B. (2009). Src kinases as therapeutic targets for cancer. Nature Reviews Clinical Oncology, 6(10), 587-595.
-
(2009)
Nature Reviews Clinical Oncology
, vol.6
, Issue.10
, pp. 587-595
-
-
Kim, L.C.1
Song, L.2
Haura, E.B.3
-
43
-
-
0038386613
-
Src family kinases in tumor progression and metastasis
-
DOI 10.1023/A:1023772912750
-
Summy, J. M., & Gallick, G. E. (2003). Src family kinases in tumor progression and metastasis. Cancer and Metastasis Reviews, 22(4), 337-358. (Pubitemid 36791891)
-
(2003)
Cancer and Metastasis Reviews
, vol.22
, Issue.4
, pp. 337-358
-
-
Summy, J.M.1
Gallick, G.E.2
-
44
-
-
77951474381
-
Src kinase inhibitors: An emerging therapeutic treatment option for prostate cancer
-
Edwards, J. (2010). Src kinase inhibitors: an emerging therapeutic treatment option for prostate cancer. Expert Opinion on Investigational Drugs, 19(5), 605-614.
-
(2010)
Expert Opinion on Investigational Drugs
, vol.19
, Issue.5
, pp. 605-614
-
-
Edwards, J.1
-
45
-
-
66149164441
-
SRC family kinase activity is up-regulated in hormone-refractory prostate cancer
-
Tatarov, O., Mitchell, T. J., Seywright, M., Leung, H. Y., Brunton, V. G., & Edwards, J. (2009). SRC family kinase activity is up-regulated in hormone-refractory prostate cancer. Clinical Cancer Research, 15(10), 3540-3549.
-
(2009)
Clinical Cancer Research
, vol.15
, Issue.10
, pp. 3540-3549
-
-
Tatarov, O.1
Mitchell, T.J.2
Seywright, M.3
Leung, H.Y.4
Brunton, V.G.5
Edwards, J.6
-
46
-
-
27144547509
-
Action of the Src family kinase inhibitor, dasatinib (BMS-354825), on human prostate cancer cells
-
DOI 10.1158/0008-5472.CAN-05-1731
-
Nam, S., Kim, D., Cheng, J. Q., et al. (2005). Action of the src family kinase inhibitor, dasatinib (BMS-354825), on human prostate cancer cells. Cancer Research, 65(20), 9185-9189. (Pubitemid 41507982)
-
(2005)
Cancer Research
, vol.65
, Issue.20
, pp. 9185-9189
-
-
Nam, S.1
Kim, D.2
Cheng, J.Q.3
Zhang, S.4
Lee, J.-H.5
Buettner, R.6
Mirosevich, J.7
Lee, F.Y.8
Jove, R.9
-
47
-
-
62549089748
-
Dasatinib is a potent inhibitor of tumour-associated macrophages, osteoclasts and the FMS receptor
-
Brownlow, N., Mol, C., Hayford, C., Ghaem-Maghami, S., & Dibb, N. (2008). Dasatinib is a potent inhibitor of tumour-associated macrophages, osteoclasts and the FMS receptor. Leukemia, 23(3), 590-594.
-
(2008)
Leukemia
, vol.23
, Issue.3
, pp. 590-594
-
-
Brownlow, N.1
Mol, C.2
Hayford, C.3
Ghaem-Maghami, S.4
Dibb, N.5
-
48
-
-
77953229623
-
Src family kinase/abl inhibitor dasatinib suppresses proliferation and enhances differentiation of osteoblasts
-
Lee, Y., Huang, C., Murshed, M., Chu, K., Araujo, J. C., & Ye, X. (2010). Src family kinase/abl inhibitor dasatinib suppresses proliferation and enhances differentiation of osteoblasts. Oncogene, 29(22), 3196-3207.
-
(2010)
Oncogene
, vol.29
, Issue.22
, pp. 3196-3207
-
-
Lee, Y.1
Huang, C.2
Murshed, M.3
Chu, K.4
Araujo, J.C.5
Ye, X.6
-
49
-
-
84888130823
-
Docetaxel and dasatinib or placebo in men with metastatic castration-resistant prostate cancer (READY): A randomised, double-blind phase 3 trial
-
Araujo, J. C., Trudel, G. C., Saad, F., Armstrong, A. J., Yu, E. Y., Bellmunt, J., et al. (2013). Docetaxel and dasatinib or placebo in men with metastatic castration-resistant prostate cancer (READY): a randomised, double-blind phase 3 trial. Lancet Oncol, 14(13), 1307-1316.
-
(2013)
Lancet Oncol
, vol.14
, Issue.13
, pp. 1307-1316
-
-
Araujo, J.C.1
Trudel, G.C.2
Saad, F.3
Armstrong, A.J.4
Yu, E.Y.5
Bellmunt, J.6
-
50
-
-
83855162892
-
Dasatinib combined with docetaxel for castration-resistant prostate cancer
-
Araujo, J. C., Mathew, P., Armstrong, A. J., et al. (2012). Dasatinib combined with docetaxel for castration-resistant prostate cancer. Cancer, 118(1), 63-71.
-
(2012)
Cancer
, vol.118
, Issue.1
, pp. 63-71
-
-
Araujo, J.C.1
Mathew, P.2
Armstrong, A.J.3
-
51
-
-
33645736007
-
Thalidomide derivative CC-4047 inhibits osteoclast formation by down-regulation of PU.1
-
Anderson, G., Gries, M., Kurihara, N., et al. (2006). Thalidomide derivative CC-4047 inhibits osteoclast formation by down-regulation of PU.1. Blood, 107(8), 3098-3105.
-
(2006)
Blood
, vol.107
, Issue.8
, pp. 3098-3105
-
-
Anderson, G.1
Gries, M.2
Kurihara, N.3
-
52
-
-
33947212926
-
Initial modulation of the tumor microenvironment accounts for thalidomide activity in prostate cancer
-
DOI 10.1158/1078-0432.CCR-06-1938
-
Efstathiou, E., Troncoso, P., Wen, S., et al. (2007). Initial modulation of the tumor microenvironment accounts for thalidomide activity in prostate cancer. Clinical Cancer Research, 13(4), 1224-1231. (Pubitemid 46424064)
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.4
, pp. 1224-1231
-
-
Efstathiou, E.1
Troncoso, P.2
Wen, S.3
Do, K.-A.4
Pettaway, C.A.5
Pisters, L.L.6
McDonnell, T.J.7
Logothetis, C.J.8
-
53
-
-
47649085380
-
Thalidomide and lenalidomide: Mechanism-based potential drug combinations
-
DOI 10.1080/10428190802005191, PII 792758569
-
Vallet, S., Palumbo, A., Raje, N., et al. (2008). Thalidomide and lenalidomide: mechanism-based potential drug combinations. Leuk Lymphoma, 49(7), 1238-1245. (Pubitemid 352015786)
-
(2008)
Leukemia and Lymphoma
, vol.49
, Issue.7
, pp. 1238-1245
-
-
Vallet, S.1
Palumbo, A.2
Raje, N.3
Boccadoro, M.4
Anderson, K.C.5
-
54
-
-
4344682179
-
Randomized phase II trial of docetaxel plus thalidomide in androgen-independent prostate cancer
-
DOI 10.1200/JCO.2004.05.074
-
Dahut, W. L., Gulley, J. L., Arlen, P. M., et al. (2004). Randomized phase II trial of docetaxel plus thalidomide in androgen-independent prostate cancer. Journal of Clinical Oncology, 22(13), 2532-2539. (Pubitemid 41103740)
-
(2004)
Journal of Clinical Oncology
, vol.22
, Issue.13
, pp. 2532-2539
-
-
Dahut, W.L.1
Gulley, J.L.2
Arlen, P.M.3
Liu, Y.4
Fedenko, K.M.5
Steinberg, S.M.6
Wright, J.J.7
Parnes, H.8
Chen, C.C.9
Jones, E.10
Parker, C.E.11
Linehan, W.M.12
Figg, W.D.13
-
56
-
-
0032877615
-
Tyrosine kinases expressed in vivo by human prostate cancer bone marrow metastases and loss of the type 1 insulin-like growth factor receptor
-
Chott, A., Sun, Z., Morganstern, D., et al. (1999). Tyrosine kinases expressed in vivo by human prostate cancer bone marrow metastases and loss of the type 1 insulin-like growth factor receptor. The American Journal of Pathology, 155(4), 1271-1279. (Pubitemid 29488934)
-
(1999)
American Journal of Pathology
, vol.155
, Issue.4
, pp. 1271-1279
-
-
Chott, A.1
Sun, Z.2
Morganstem, D.3
Pan, J.4
Li, T.5
Susani, M.6
Mosberger, I.7
Upton, M.P.8
Bubley, G.J.9
Balk, S.P.10
-
57
-
-
70149095573
-
Cross-talk between the VEGF-A and HGF signalling pathways in endothelial cells
-
Sulpice, E., Ding, S., Muscatelli-Groux, B., et al. (2009). Cross-talk between the VEGF-A and HGF signalling pathways in endothelial cells. Biology of the Cell, 101(9), 525-539.
-
(2009)
Biology of the Cell
, vol.101
, Issue.9
, pp. 525-539
-
-
Sulpice, E.1
Ding, S.2
Muscatelli-Groux, B.3
-
58
-
-
84860385747
-
Hepatocyte growth factor-induced BMP-2 expression is mediated by c-met receptor, FAK, JNK, Runx2, and p300 pathways in human osteoblasts
-
Tsai, S., Huang, Y., Yang, W., & Tang, C. (2012). Hepatocyte growth factor-induced BMP-2 expression is mediated by c-met receptor, FAK, JNK, Runx2, and p300 pathways in human osteoblasts. International Immunopharmacology, 13(2), 156-162.
-
(2012)
International Immunopharmacology
, vol.13
, Issue.2
, pp. 156-162
-
-
Tsai, S.1
Huang, Y.2
Yang, W.3
Tang, C.4
-
59
-
-
84871962904
-
Targeted MET inhibition in castration-resistant prostate cancer: A randomized phase II study and biomarker analysis with rilotumumab plus mitoxantrone and prednisone
-
Ryan, C. J., Rosenthal, M., Ng, S., et al. (2013). Targeted MET inhibition in castration-resistant prostate cancer: a randomized phase II study and biomarker analysis with rilotumumab plus mitoxantrone and prednisone. Clinical Cancer Research, 19(1), 215-224.
-
(2013)
Clinical Cancer Research
, vol.19
, Issue.1
, pp. 215-224
-
-
Ryan, C.J.1
Rosenthal, M.2
Ng, S.3
-
60
-
-
84861690508
-
Randomized, double-blind, placebo-controlled phase III trial comparing docetaxel and prednisone with or without bevacizumab in men with metastatic castration-resistant prostate cancer: CALGB 90401
-
Kelly, W. K., Halabi, S., Carducci, M., et al. (2012). Randomized, double-blind, placebo-controlled phase III trial comparing docetaxel and prednisone with or without bevacizumab in men with metastatic castration-resistant prostate cancer: CALGB 90401. Journal of Clinical Oncology, 30(13), 1534-1540.
-
(2012)
Journal of Clinical Oncology
, vol.30
, Issue.13
, pp. 1534-1540
-
-
Kelly, W.K.1
Halabi, S.2
Carducci, M.3
-
61
-
-
84874787799
-
Cabozantinib in patients with advanced prostate cancer: Results of a phase II randomized discontinuation trial
-
Smith, D. C., Smith, M. R., Sweeney, C., et al. (2013). Cabozantinib in patients with advanced prostate cancer: results of a phase II randomized discontinuation trial. Journal of Clinical Oncology, 31(4), 412-419.
-
(2013)
Journal of Clinical Oncology
, vol.31
, Issue.4
, pp. 412-419
-
-
Smith, D.C.1
Smith, M.R.2
Sweeney, C.3
-
62
-
-
33845394305
-
Identification of ABR-215050 as lead second generation quinoline-3- carboxamide anti-angiogenic agent for the treatment of prostate cancer
-
DOI 10.1002/pros.20509
-
Isaacs, J. T., Pili, R., Qian, D. Z., et al. (2006). Identification of ABR-215050 as lead second generation quinoline-3-carboxamide anti-angiogenic agent for the treatment of prostate cancer. Prostate, 66(16), 1768-1778. (Pubitemid 44893902)
-
(2006)
Prostate
, vol.66
, Issue.16
, pp. 1768-1778
-
-
Isaacs, J.T.1
Pili, R.2
Qian, D.Z.3
Dalrymple, S.L.4
Garrison, J.B.5
Kyprianou, N.6
Bjork, A.7
Olsson, A.8
Leanderson, T.9
-
63
-
-
77956562643
-
The long and winding road for the development of tasquinimod as an oral second-generation quinoline-3-carboxamide antiangiogenic drug for the treatment of prostate cancer
-
Isaacs, J. T. (2010). The long and winding road for the development of tasquinimod as an oral second-generation quinoline-3-carboxamide antiangiogenic drug for the treatment of prostate cancer. Expert Opinion on Investigational Drugs, 19(10), 1235-1243.
-
(2010)
Expert Opinion on Investigational Drugs
, vol.19
, Issue.10
, pp. 1235-1243
-
-
Isaacs, J.T.1
-
64
-
-
77952223624
-
Tasquinimod (ABR-215050), a quinoline-3-carboxamide anti-angiogenic agent, modulates the expression of thrombospondin-1 in human prostate tumors
-
Olsson, A., Björk, A., Vallon-Christersson, J., Isaacs, J. T., & Leanderson, T. (2010). Tasquinimod (ABR-215050), a quinoline-3-carboxamide anti-angiogenic agent, modulates the expression of thrombospondin-1 in human prostate tumors. Molecular Cancer, 9(1), 107.
-
(2010)
Molecular Cancer
, vol.9
, Issue.1
, pp. 107
-
-
Olsson, A.1
Björk, A.2
Vallon-Christersson, J.3
Isaacs, J.T.4
Leanderson, T.5
-
65
-
-
84874342427
-
Tasquinimod is an allosteric modulator of HDAC4 survival signaling within the compromised cancer microenvironment
-
Isaacs, J. T., Antony, L., Dalrymple, S. L., et al. (2013). Tasquinimod is an allosteric modulator of HDAC4 survival signaling within the compromised cancer microenvironment. Cancer Research, 73(4), 1386-1399.
-
(2013)
Cancer Research
, vol.73
, Issue.4
, pp. 1386-1399
-
-
Isaacs, J.T.1
Antony, L.2
Dalrymple, S.L.3
-
66
-
-
84860319412
-
Inhibition of metastasis in a castration resistant prostate cancer model by the quinoline-3-carboxamide tasquinimod (ABR-215050)
-
Jennbacken, K., Welén, K., Olsson, A., et al. (2012). Inhibition of metastasis in a castration resistant prostate cancer model by the quinoline-3-carboxamide tasquinimod (ABR-215050). Prostate, 72(8), 913-924.
-
(2012)
Prostate
, vol.72
, Issue.8
, pp. 913-924
-
-
Jennbacken, K.1
Welén, K.2
Olsson, A.3
-
67
-
-
70349952393
-
Open-label, clinical phase I studies of tasquinimod in patients with castration-resistant prostate cancer
-
Bratt, O., Häggman, M., Ahlgren, G., Nordle, Ö., Björk, A., & Damber, J. (2009). Open-label, clinical phase I studies of tasquinimod in patients with castration-resistant prostate cancer. British Journal of Cancer, 101(8), 1233-1240.
-
(2009)
British Journal of Cancer
, vol.101
, Issue.8
, pp. 1233-1240
-
-
Bratt, O.1
Häggman, M.2
Ahlgren, G.3
Nordle, Ö.4
Björk, A.5
Damber, J.6
-
68
-
-
80054761310
-
Phase II randomized, double-blind, placebo-controlled study of tasquinimod in men with minimally symptomatic metastatic castrate-resistant prostate cancer
-
Pili, R., Häggman, M., Stadler, W. M., et al. (2011). Phase II randomized, double-blind, placebo-controlled study of tasquinimod in men with minimally symptomatic metastatic castrate-resistant prostate cancer. Journal of Clinical Oncology, 29(30), 4022-4028.
-
(2011)
Journal of Clinical Oncology
, vol.29
, Issue.30
, pp. 4022-4028
-
-
Pili, R.1
Häggman, M.2
Stadler, W.M.3
-
69
-
-
84867676575
-
Tasquinimod and survival in men with metastatic castration-resistant prostate cancer: Results of long-term follow-up of a randomized phase II placebo-controlled trial
-
Armstrong, A. J., Haggman, M., Stadler, W. M., et al. (2012). Tasquinimod and survival in men with metastatic castration-resistant prostate cancer: results of long-term follow-up of a randomized phase II placebo-controlled trial. Journal of Clinical Oncology, 30(15 Suppl), 4550.
-
(2012)
Journal of Clinical Oncology
, vol.30
, Issue.15 SUPPL.
, pp. 4550
-
-
Armstrong, A.J.1
Haggman, M.2
Stadler, W.M.3
-
70
-
-
84866770294
-
Increased survival with enzalutamide in prostate cancer after chemotherapy
-
Scher, H. I., Fizazi, K., Saad, F., et al. (2012). Increased survival with enzalutamide in prostate cancer after chemotherapy. The New England Journal of Medicine, 367(13), 1187-1197.
-
(2012)
The New England Journal of Medicine
, vol.367
, Issue.13
, pp. 1187-1197
-
-
Scher, H.I.1
Fizazi, K.2
Saad, F.3
-
71
-
-
84872078210
-
Abiraterone in metastatic prostate cancer without previous chemotherapy
-
Ryan, C. J., Smith, M. R., de Bono, J. S., et al. (2013). Abiraterone in metastatic prostate cancer without previous chemotherapy. The New England Journal of Medicine, 368(2), 138-148.
-
(2013)
The New England Journal of Medicine
, vol.368
, Issue.2
, pp. 138-148
-
-
Ryan, C.J.1
Smith, M.R.2
De Bono, J.S.3
-
72
-
-
84870243969
-
Effect of abiraterone acetate and prednisone compared with placebo and prednisone on pain control and skeletal-related events in patients with metastatic castration-resistant prostate cancer: Exploratory analysis of data from the COU-AA-301 randomised trial
-
Logothetis, C. J., Basch, E., Molina, A., et al. (2012). Effect of abiraterone acetate and prednisone compared with placebo and prednisone on pain control and skeletal-related events in patients with metastatic castration-resistant prostate cancer: exploratory analysis of data from the COU-AA-301 randomised trial. The lancet oncology., 13, 1210-7.
-
(2012)
The Lancet Oncology
, vol.13
, pp. 1210-1217
-
-
Logothetis, C.J.1
Basch, E.2
Molina, A.3
-
73
-
-
65649090203
-
Development of a second-generation antiandrogen for treatment of advanced prostate cancer
-
Tran, C., Ouk, S., Clegg, N. J., et al. (2009). Development of a second-generation antiandrogen for treatment of advanced prostate cancer. Science, 324(5928), 787-790.
-
(2009)
Science
, vol.324
, Issue.5928
, pp. 787-790
-
-
Tran, C.1
Ouk, S.2
Clegg, N.J.3
-
74
-
-
84886720136
-
Impact of enzalutamide, an androgen receptor signaling inhibitor, on time to first skeletal related event (SRE) and pain in the phase 3 AFFIRM study
-
Fizazi, K., Scher, H., Saad, F., et al. (2012). Impact of enzalutamide, an androgen receptor signaling inhibitor, on time to first skeletal related event (SRE) and pain in the phase 3 AFFIRM study. Annals of Oncology, 23, 295-296.
-
(2012)
Annals of Oncology
, vol.23
, pp. 295-296
-
-
Fizazi, K.1
Scher, H.2
Saad, F.3
-
75
-
-
79952278967
-
The cathepsin K inhibitor odanacatib suppresses bone resorption in women with breast cancer and established bone metastases: Results of a 4-week, double-blind, randomized, controlled trial
-
Jensen, A. B., Wynne, C., Ramirez, G., et al. (2010). The cathepsin K inhibitor odanacatib suppresses bone resorption in women with breast cancer and established bone metastases: results of a 4-week, double-blind, randomized, controlled trial. Clinical Breast Cancer, 10(6), 452-458.
-
(2010)
Clinical Breast Cancer
, vol.10
, Issue.6
, pp. 452-458
-
-
Jensen, A.B.1
Wynne, C.2
Ramirez, G.3
-
76
-
-
15944377835
-
Blood and bone: Two tissues whose fates are intertwined to create the hematopoietic stem-cell niche
-
Taichman, R. S. (2005). Blood and bone: two tissues whose fates are intertwined to create the hematopoietic stem-cell niche. Blood, 105(7), 2631-2639.
-
(2005)
Blood
, vol.105
, Issue.7
, pp. 2631-2639
-
-
Taichman, R.S.1
-
77
-
-
63049104211
-
Microenvironmental regulation of metastasis
-
Joyce, J. A., & Pollard, J.W. (2008). Microenvironmental regulation of metastasis. Nature Reviews Cancer, 9(4), 239-252.
-
(2008)
Nature Reviews Cancer
, vol.9
, Issue.4
, pp. 239-252
-
-
Joyce, J.A.1
Pollard, J.W.2
-
78
-
-
35548936833
-
Models, mechanisms and clinical evidence for cancer dormancy
-
Aguirre-Ghiso, J. A. (2007). Models, mechanisms and clinical evidence for cancer dormancy. Nature Reviews Cancer, 7(11), 834-846.
-
(2007)
Nature Reviews Cancer
, vol.7
, Issue.11
, pp. 834-846
-
-
Aguirre-Ghiso, J.A.1
|