MicroRNA-195 regulates steroid receptor coactivator-3 protein expression in hepatocellular carcinoma cells

Tumor Biology

Volumn 35, Issue 7, 2014, Pages 6955-6960

  Jiang, Hong Lei ^a   Yu, Hao ^a   Ma, Xu ^a   Xu, Dong ^a   Lin, Guo Fu ^a   Ma, Dong Yan ^a   Jin, Jun Zhe ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

Author keywords

Hepatocellular carcinoma; miR 195; Proliferation; SRC 3

Indexed keywords

MICRORNA; MICRORNA 195; STEROID RECEPTOR COACTIVATOR 3; UNCLASSIFIED DRUG;

3' UNTRANSLATED REGION; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; HEPATOCELLULAR CARCINOMA CELL LINE; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; LIVER CELL CARCINOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR GROWTH; UPREGULATION;

CARCINOMA, HEPATOCELLULAR; CELL PROLIFERATION; GENE EXPRESSION REGULATION, NEOPLASTIC; HEP G2 CELLS; HUMANS; LIVER NEOPLASMS; MICRORNAS; NUCLEAR RECEPTOR COACTIVATOR 3;

EID: 84905054289     PISSN: 10104283     EISSN: 14230380     Source Type: Journal    
DOI: 10.1007/s13277-014-1933-x     Document Type: Article

References (20)

1. York B, O'Malley BW. Steroid receptor coactivator (src) family: Masters of systems biology. J Biol Chem. 2010;285:38743-50.
2. Xu J, Li Q. Review of the in vivo functions of the p160 steroid receptor coactivator family. Mol Endocrinol (Baltimore, Md). 2003;17:1681-92. (Pubitemid 37072287)
3. Liao L, Kuang SQ, Yuan Y, Gonzalez SM, O'Malley BW, Xu J. Molecular structure and biological function of the cancer-amplified nuclear receptor coactivator SRC-3/AIB1. J Steroid Biochem Mol Biol. 2002;83:3-14. (Pubitemid 37040636)
4. Xu J, Liao L, Ning G, Yoshida-Komiya H, Deng C, O'Malley BW. The steroid receptor coactivator src-3 (p/CIP/RAC3/AIB1/ACTR/TRAM-1) is required for normal growth, puberty, female reproductive function, and mammary gland development. Proc Natl Acad Sci U S A. 2000;97:6379-84. (Pubitemid 30412722)
5. Louet JF, Coste A, Amazit L, Tannour-Louet M, Wu RC, Tsai SY, et al. Oncogenic steroid receptor coactivator-3 is a key regulator of the white adipogenic program. Proc Natl Acad Sci U S A. 2006;103:17868-73. (Pubitemid 44852252)
6. Coste A, Louet JF, Lagouge M, Lerin C, Antal MC, Meziane H, et al. The genetic ablation of SRC-3 protects against obesity and improves insulin sensitivity by reducing the acetylation of PGC-1{alpha}. Proc Natl Acad Sci U S A. 2008;105:17187-92.
7. Tien JC, Xu J. Steroid receptor coactivator-3 as a potential molecular target for cancer therapy. Expert Opin Ther Targets. 2012;16:1085-96.
8. Ma G, Ren Y, Wang K, He J. SRC-3 has a role in cancer other than as a nuclear receptor coactivator. Int J Biol Sci. 2011;7:664-72.
9. Lydon JP, O'Malley BW. Minireview: Steroid receptor coactivator-3: a multifarious coregulator in mammary gland metastasis. Endocrinology. 2011;152:19-25.
10. Ling H, Fabbri M, Calin GA. Micrornas and other non-coding rnas as targets for anticancer drug development. Nat Rev Drug Discov. 2013;12:847-65.
11. Sun K, Lai EC. Adult-specific functions of animal micrornas. Nat Rev Genet. 2013;14:535-48.
12. Gougelet A, Colnot S. [microrna: new diagnostic and therapeutic tools in liver disease?]. Medecine Sciences. 2013;29:861-7.
13. Callegari E, Elamin BK, Sabbioni S, Gramantieri L, Negrini M. Role of micrornas in hepatocellular carcinoma: A clinical perspective. Onco Targets and Therapy. 2013;6:1167-78.
14. Karmakar S, Gao T, Pace MC, Oesterreich S, Smith CL. Cooperative activation of cyclin D1 and progesterone receptor gene expression by the SRC-3 coactivator and SMRT corepressor. Mol Endocrinol. 2010;24:1187-202.
15. Xu T, Zhu Y, Xiong Y, Ge YY, Yun JP, Zhuang SM. Microrna-195 suppresses tumorigenicity and regulates G1/S transition of human hepatocellular carcinoma cells. Hepatology (Baltimore, Md). 2009;50:113-21.
16. Yang X, Yu J, Yin J, Xiang Q, Tang H, Lei X. Mir-195 regulates cell apoptosis of human hepatocellular carcinoma cells by targeting LATS2. Die Pharmazie. 2012;67:645-51.
17. Mussi P, Yu C, O'Malley BW, Xu J. Stimulation of steroid receptor coactivator-3 (src-3) gene overexpression by a positive regulatory loop of E2F1 and SRC-3. Mol Endocrinol (Baltimore, Md). 2006;20:3105-19. (Pubitemid 44833559)
18. Garabedian MJ, Logan SK. Atypical regulation of SRC-3. Trends Biochem Sci. 2008;33:301-4.
19. Yi P, Feng Q, Amazit L, Lonard DM, Tsai SY, Tsai MJ, et al. A typical protein kinase c regulates dual pathways for degradation of the oncogenic coactivator SRC-3/AIB1. Mol Cell. 2008;29:465-76. (Pubitemid 351291678)
20. Long W, Foulds CE, Qin J, Liu J, Ding C, Lonard DM, et al. ERK3 signals through SRC-3 coactivator to promote human lung cancer cell invasion. J Clin Invest. 2012;122:1869-80.