-
1
-
-
78649703966
-
Rewiring of genetic networks in response to DNA damage
-
Bandyopadhyay, S. et al. Rewiring of genetic networks in response to DNA damage. Science 330, 1385-1389 (2010
-
(2010)
Science
, vol.330
, pp. 1385-1389
-
-
Bandyopadhyay, S.1
-
2
-
-
84861989206
-
Functional repurposing revealed by comparing S. Pombe and S. Cerevisiae genetic interactions
-
Frost, A. et al. Functional repurposing revealed by comparing S. pombe and S. cerevisiae genetic interactions. Cell 149, 1339-1352 (2012
-
(2012)
Cell
, vol.149
, pp. 1339-1352
-
-
Frost, A.1
-
3
-
-
63449128473
-
Comprehensive characterization of genes required for protein folding in the endoplasmic reticulum
-
Jonikas, M.C. et al. Comprehensive characterization of genes required for protein folding in the endoplasmic reticulum. Science 323, 1693-1697 (2009
-
(2009)
Science
, vol.323
, pp. 1693-1697
-
-
Jonikas, M.C.1
-
4
-
-
54249107599
-
Conservation and rewiring of functional modules revealed by an epistasis map in fission yeast
-
Roguev, A. et al. Conservation and rewiring of functional modules revealed by an epistasis map in fission yeast. Science 322, 405-410 (2008
-
(2008)
Science
, vol.322
, pp. 405-410
-
-
Roguev, A.1
-
5
-
-
26844489762
-
Exploration of the function and organization of the yeast early secretory pathway through an epistatic miniarray profile
-
Schuldiner, M. et al. Exploration of the function and organization of the yeast early secretory pathway through an epistatic miniarray profile. Cell 123, 507-519 (2005
-
(2005)
Cell
, vol.123
, pp. 507-519
-
-
Schuldiner, M.1
-
6
-
-
0035861532
-
Systematic genetic analysis with ordered arrays of yeast deletion mutants
-
Tong, A.H. et al. Systematic genetic analysis with ordered arrays of yeast deletion mutants. Science 294, 2364-2368 (2001
-
(2001)
Science
, vol.294
, pp. 2364-2368
-
-
Tong, A.H.1
-
7
-
-
10744230485
-
Global mapping of the yeast genetic interaction network
-
Tong, A.H. et al. Global mapping of the yeast genetic interaction network. Science 303, 808-813 (2004
-
(2004)
Science
, vol.303
, pp. 808-813
-
-
Tong, A.H.1
-
8
-
-
34147217542
-
Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map
-
Collins, S.R. et al. Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map. Nature 446, 806-810 (2007
-
(2007)
Nature
, vol.446
, pp. 806-810
-
-
Collins, S.R.1
-
9
-
-
84879319702
-
Integrated platform for genome-wide screening and construction of high-density genetic interaction maps in mammalian cells
-
Kampmann, M., Bassik, M.C. & Weissman, J.S. Integrated platform for genome-wide screening and construction of high-density genetic interaction maps in mammalian cells. Proc. Natl. Acad. Sci. USA 110, E2317-E2326 (2013
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
-
-
Kampmann, M.1
Bassik, M.C.2
Weissman, J.S.3
-
10
-
-
84874113985
-
A systematic mammalian genetic interaction map reveals pathways underlying ricin susceptibility
-
Bassik, M.C. et al. A systematic mammalian genetic interaction map reveals pathways underlying ricin susceptibility. Cell 152, 909-922 (2013
-
(2013)
Cell
, vol.152
, pp. 909-922
-
-
Bassik, M.C.1
-
11
-
-
84877303028
-
Mapping genetic interactions in human cancer cells with RNAi and multiparametric phenotyping
-
Laufer, C., Fischer, B., Billmann, M., Huber, W. & Boutros, M. Mapping genetic interactions in human cancer cells with RNAi and multiparametric phenotyping. Nat. Methods 10, 427-431 (2013
-
(2013)
Nat. Methods
, vol.10
, pp. 427-431
-
-
Laufer, C.1
Fischer, B.2
Billmann, M.3
Huber, W.4
Boutros, M.5
-
12
-
-
84877262605
-
Quantitative genetic-interaction mapping in mammalian cells
-
Roguev, A. et al. Quantitative genetic-interaction mapping in mammalian cells. Nat. Methods 10, 432-437 (2013
-
(2013)
Nat. Methods
, vol.10
, pp. 432-437
-
-
Roguev, A.1
-
13
-
-
67349251607
-
Rapid creation and quantitative monitoring of high-coverage shRNA libraries
-
Bassik, M.C. et al. Rapid creation and quantitative monitoring of high-coverage shRNA libraries. Nat. Methods 6, 443-445 (2009
-
(2009)
Nat. Methods
, vol.6
, pp. 443-445
-
-
Bassik, M.C.1
-
14
-
-
84864326893
-
Use and abuse of RNAi to study mammalian gene function
-
Kaelin, W.G. Jr. Use and abuse of RNAi to study mammalian gene function. Science 337, 421-422 (2012
-
(2012)
Science
, vol.337
, pp. 421-422
-
-
Kaelin Jr., W.G.1
-
15
-
-
79961062492
-
Systematic investigation of genetic vulnerabilities across cancer cell lines reveals lineage-specific dependencies in ovarian cancer
-
Cheung, H.W. et al. Systematic investigation of genetic vulnerabilities across cancer cell lines reveals lineage-specific dependencies in ovarian cancer. Proc. Natl. Acad. Sci. USA 108, 12372-12377 (2011
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 12372-12377
-
-
Cheung, H.W.1
-
16
-
-
58149521944
-
Highly parallel identification of essential genes in cancer cells
-
Luo, B. et al. Highly parallel identification of essential genes in cancer cells. Proc. Natl. Acad. Sci. USA 105, 20380-20385 (2008
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 20380-20385
-
-
Luo, B.1
-
17
-
-
66149091940
-
A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene
-
Luo, J. et al. A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene. Cell 137, 835-848 (2009
-
(2009)
Cell
, vol.137
, pp. 835-848
-
-
Luo, J.1
-
18
-
-
78651312134
-
Toolkit for evaluating genes required for proliferation and survival using tetracycline-regulated RNAi
-
Zuber, J. et al. Toolkit for evaluating genes required for proliferation and survival using tetracycline-regulated RNAi. Nat. Biotechnol. 29, 79-83 (2011
-
(2011)
Nat. Biotechnol
, vol.29
, pp. 79-83
-
-
Zuber, J.1
-
19
-
-
84874687019
-
Repurposing crispr as an rna-guided platform for sequence-specific control of gene expression
-
Qi, L.S. et al. Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression. Cell 152, 1173-1183 (2013
-
(2013)
Cell
, vol.152
, pp. 1173-1183
-
-
Qi, L.S.1
-
20
-
-
84880571335
-
CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes
-
Gilbert, L.A. et al. CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes. Cell 154, 442-451 (2013
-
(2013)
Cell
, vol.154
, pp. 442-451
-
-
Gilbert, L.A.1
-
21
-
-
84892749369
-
Genetic screens in human cells using the CRISPR-Cas9 system
-
Wang, T., Wei, J.J., Sabatini, D.M. & Lander, E.S. Genetic screens in human cells using the CRISPR-Cas9 system. Science 343, 80-84 (2013
-
(2013)
Science
, vol.343
, pp. 80-84
-
-
Wang, T.1
Wei, J.J.2
Sabatini, D.M.3
Lander, E.S.4
-
22
-
-
84892765883
-
Genome-scale CRISPR-Cas9 knockout screening in human cells
-
Shalem, O. et al. Genome-scale CRISPR-Cas9 knockout screening in human cells. Science 343, 84-87 (2013
-
(2013)
Science
, vol.343
, pp. 84-87
-
-
Shalem, O.1
-
23
-
-
79952303452
-
The pinducer lentiviral toolkit for inducible rna interference in vitro and in vivo
-
Meerbrey, K.L. et al. The pINDUCER lentiviral toolkit for inducible RNA interference in vitro and in vivo. Proc. Natl. Acad. Sci. USA 108, 3665-3670 (2011
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 3665-3670
-
-
Meerbrey, K.L.1
-
24
-
-
38849192515
-
Profiling essential genes in human mammary cells by multiplex RNAi screening
-
Silva, J.M. et al. Profiling essential genes in human mammary cells by multiplex RNAi screening. Science 319, 617-620 (2008
-
(2008)
Science
, vol.319
, pp. 617-620
-
-
Silva, J.M.1
-
25
-
-
0031710033
-
A third-generation lentivirus vector with a conditional packaging system
-
Dull, T. et al. A third-generation lentivirus vector with a conditional packaging system. J. Virol. 72, 8463-8471 (1998
-
(1998)
J. Virol
, vol.72
, pp. 8463-8471
-
-
Dull, T.1
-
26
-
-
0029996147
-
In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector
-
Naldini, L. et al. In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector. Science 272, 263-267 (1996
-
(1996)
Science
, vol.272
, pp. 263-267
-
-
Naldini, L.1
-
27
-
-
9444225935
-
Java treeview: Extensible visualization of microarray data
-
Saldanha, A.J. Java TreeView: Extensible visualization of microarray data. Bioinformatics 20, 3246-3248 (2004
-
(2004)
Bioinformatics
, vol.20
, pp. 3246-3248
-
-
Saldanha, A.J.1
-
28
-
-
84888262057
-
Next-generation nampt inhibitors identified by sequential high-Throughput phenotypic chemical and functional genomic screens
-
Matheny, C.J. et al. Next-generation NAMPT inhibitors identified by sequential high-Throughput phenotypic chemical and functional genomic screens. Chem. Biol. 20, 1352-1363 (2013
-
(2013)
Chem. Biol
, vol.20
, pp. 1352-1363
-
-
Matheny, C.J.1
-
29
-
-
0032441150
-
Cluster analysis and display of genome-wide expression patterns
-
Eisen, M.B., Spellman, P.T., Brown, P.O. & Botstein, D. Cluster analysis and display of genome-wide expression patterns. Proc. Natl. Acad. Sci. USA 95, 14863-14868 (1998
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 14863-14868
-
-
Eisen, M.B.1
Spellman, P.T.2
Brown, P.O.3
Botstein, D.4
|