Aerobic exercise increases hippocampal volume and improves memory in multiple sclerosis: Preliminary findings

Neurocase

Volumn 20, Issue 6, 2014, Pages 695-697

  Leavitt, V M ^a,b   Cirnigliaro, C ^c,d   Cohen, A ^a   Farag, A ^c   Brooks, M ^c   Wecht, J M ^c   Wylie, G R ^a,b   Chiaravalloti, N D ^a,b   DeLuca, J ^a,b   Sumowski, J F ^a,b  

^a KESSLER FOUNDATION   (United States)

^b RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

^d KESSLER INSTITUTE FOR REHABILITATION   (United States)

Author keywords

Aerobic; Functional connectivity; Hippocampus; Memory; Multiple sclerosis

Indexed keywords

ADULT; AEROBIC EXERCISE; ARTICLE; BRIEF VISUAL MEMORY TEST; CALIFORNIA VERBAL LEARNING TEST; CASE REPORT; COGNITIVE DEFECT; CYCLING; FEMALE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HIPPOCAMPUS; HUMAN; LEARNING TEST; MEMORY; MEMORY DISORDER; MULTIPLE SCLEROSIS; PACED AUDITORY SERIAL ADDITION TEST; PILOT STUDY; PSYCHOLOGIC TEST; QUALITY OF LIFE; STROOP TEST; SYMBOL DIGIT MODALITY TEST; VISUAL MEMORY; WORKING MEMORY; BRAIN; CONTROLLED STUDY; KINESIOTHERAPY; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; PSYCHOLOGY; RANDOMIZED CONTROLLED TRIAL; TREATMENT OUTCOME;

ADULT; BRAIN; EXERCISE THERAPY; FEMALE; HIPPOCAMPUS; HUMANS; MEMORY; MULTIPLE SCLEROSIS; TREATMENT OUTCOME;

EID: 84905026541     PISSN: 13554794     EISSN: 14653656     Source Type: Journal    
DOI: 10.1080/13554794.2013.841951     Document Type: Article

References (7)

1. Cow, R. W. (1996). AFNI: Software for analysis and visualization of functional magnetic resonance neuroimages. Computers and Biomedical Research, 29, 162-173.
2. das Nair, R., Ferguson, H., Stark, D. L., & Lincoln, N. B. (2012). Memory rehabilitation for people with multiple sclerosis. Cochrane Database of Systematic Review, 3, CD008754.
3. Erickson, K. I., Voss, M. W., Prakash, R. S., Basak, C., Szabo, A., Chaddock, L., Kramer, A. F. (2011). Exercise training increases size of hippocampus and improves memory. Proceedings of the National Academy of Sciences of the United States of America, 108, 3017-3022.
4. Pajonk, F. G., Wobrock, T., Gruber, O., Scherk, H., Berner, D., Kaizl, I., Falkai, P. (2010). Hippocampal plasticity in response to exercise in schizophrenia. Archives of General Psychiatry, 67, 133-143.
5. Sicotte, N. L., Kern, K. C., Giesser, B. S., Arshanapalli, A., Schultz, A., Montag, M., Bookheimer, S. Y. (2008). Regional hippocampal atrophy in multiple sclerosis. Brain, 131, 1134-1141.
6. Thornton, A. E., & Raz, N. (1997). Memory impairment in multiple sclerosis: A quantitative review. Neuropsychology, 11, 357-366.
7. van Praag, H., Christie, B. R., Sejnowski, T. J., & Gage, F. H. (1999). Running enhances neurogenesis, learning, and long-term potentiation in mice. Proceedings of the National Academy of Sciences of the United States of America, 96, 13427-13431.