Transient serum exposure regimes to support dual differentiation of human mesenchymal stem cells

Journal of Tissue Engineering and Regenerative Medicine

Volumn 8, Issue 8, 2014, Pages 652-663

  France, L A ^a   Scotchford, C A ^a   Grant, D M ^a   Rashidi, H ^a   Popov, A A ^a   Sottile, V ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

Differentiation; Mesenchymal stem cells; Osteogenesis; Serum free medium

Indexed keywords

BODY FLUIDS; CELL ENGINEERING; FLOWCHARTING; OSTEOBLASTS; STEM CELLS; TISSUE; TISSUE ENGINEERING;

CHONDROGENIC DIFFERENTIATION; DIFFERENTIATION; HUMAN MESENCHYMAL STEM CELLS; MESENCHYMAL STEM CELL; OSTEOGENESIS; OSTEOGENIC; OSTEOGENIC DIFFERENTIATION; SERUM FREE; SERUM-FREE CONDITIONS; SERUM-FREE MEDIA;

CELL CULTURE;

ARTICLE; BIOREACTOR; BONE DEVELOPMENT; CARTILAGE CELL; CELL DIFFERENTIATION; CHONDROGENESIS; CLINICAL PROTOCOL; CULTURE MEDIUM; ENVIRONMENTAL EXPOSURE; MESENCHYMAL STEM CELL; MINERALIZATION; OSTEOBLAST; PRIORITY JOURNAL; REGENERATIVE MEDICINE; SERUM; TISSUE ENGINEERING; CELL CULTURE; CELL PROLIFERATION; CYTOLOGY; HUMAN; KINETICS; MESENCHYMAL STROMA CELL; METABOLISM; ULTRASTRUCTURE;

BIOLOGICAL MARKER; CALCIUM; MINERAL;

BIOLOGICAL MARKERS; CALCIUM; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; CHONDROGENESIS; HUMANS; KINETICS; MESENCHYMAL STROMAL CELLS; MINERALS; OSTEOGENESIS; SERUM;

EID: 84904976692     PISSN: 19326254     EISSN: 19327005     Source Type: Journal    
DOI: 10.1002/term.1567     Document Type: Article

References (39)

1. Agata H, Watanabe N, Ishii Y et al. 2009; Feasibility and efficacy of bone tissue engineering using human bone marrow stromal cells cultivated in serum-free conditions. Biochem Biophys Res Commun 382: 353-358.
2. Berger MG, Veyrat-Masson R, Rapatel C et al. 2006; Cell culture medium composition and translational adult bone marrow-derived stem cell research. Stem Cells 24: 2888-2890.
3. Bruder SP, Fink DJ, Caplan AI. 1994; Mesenchymal stem cells in bone development, bone repair, and skeletal regenaration therapy. J Cell Biochem 56: 283-294.
4. Bruder SP, Jaiswal N, Haynesworth SE. 1997; Growth kinetics, self-renewal, and the osteogenic potential of purified human mesenchymal stem cells during extensive subcultivation and following cryopreservation. J Cell Biochem 64: 278-294.
5. Cancedda R, Dozin B, Giannoni P et al. 2003; Tissue engineering and cell therapy of cartilage and bone. Matrix Biol 22: 81-91.
6. Caplan AI, Bruder SP. 2001; Mesenchymal stem cells: building blocks for molecular medicine in the 21st century. Trends Mol Med 7: 259-264.
7. Caplan AI, Pechak DG. 1987; The cellular and molecular embryology of bone formation. In Bone and Mineral Research, Peck WA (ed). Elsevier: New York; 117-184.
8. Csaki C, Schneider PR, Shakibaei M. 2008; Mesenchymal stem cells as a potential pool for cartilage tissue engineering. Ann Anat 190: 395-412.
9. Deans RJ, Moseley AB. 2000; Mesenchymal stem cells: biology and potential clinical uses. Exp Hematol 28: 875-884.
10. Edwards HK, Fay MW, Anderson SI et al. 2009; An appraisal of ultramicrotomy, FIBSEM and cryogenic FIBSEM techniques for the sectioning of biological cells on titanium substrates for TEM investigation. J Microsc 234: 16-25.
11. Farndale RW, Sayers CA, Barrett AJ. 1982; A direct spectrophotometric microassay for sulfated glycosaminoglycans in cartilage cultures. Connect Tissue Res 9: 247-248.
12. Friedman MS, Long MW, Hankenson KD. 2006; Osteogenic differentiation of human mesenchymal stem cells is regulated by bone morphogenetic protein-6. J Cell Biochem 98: 538-554.
13. Gronthos S, Simmons PJ. 1995; The growth factor requirements of STRO-1-positive human bone marrow stromal precursors under serum-deprived conditions in vitro. Blood 85: 929-940.
14. Kuznetsov SA, Friedenstein AJ, Robey PG. 1997; Factors required for bone marrow stromal fibroblast colony formation in vitro. Br J Haematol 97: 561-570.
15. Kuznetsov SA, Mankani MH, Robey PG. 2000; Effect of serum on human bone marrow stromal cells: ex vivo expansion and in vivo bone formation. Transplantation 70: 1780-1787.
16. Lee S, Kim JH, Jo CH et al. 2009; Effect of serum and growth factors on chondrogenic differentiation of synovium-derived stromal cells. Tissue Eng Part A 15: 3401-3415.
17. Lian JB, Stein GS, Stein JL et al. 1999; Regulated expression of the bone-specific osteocalcin gene by vitamins and hormones. Vitam Horm 55: 443-509.
18. Little K. 1969; Nature of osteopetrosis. Br Med J 2: 49-50.
19. Liu CH, Wu ML, Hwang SM. 2007; Optimization of serum-free medium for cord blood mesenchymal stem cells. Biochem Eng J 33: 1-9.
20. Mackay AM, Beck SC, Murphy JM et al. 1998; Chondrogenic differentiation of cultured human mesenchymal stem cells from marrow. Tissue Eng 4: 415-428.
21. Malpeli M, Randazzo N, Cancedda R et al. 2004; Serum-free growth medium sustains commitment of human articular chondrocyte through maintenance of Sox9 expression. Tissue Eng 10: 145-155.
22. Martin I, Miot S, Barbero A et al. 2007; Osteochondral tissue engineering. J Biomech 40: 750-765.
23. Montzka K, Führmann T, Wöltje M et al. 2010; Expansion of human bone marrow-derived mesenchymal stromal cells: serum-reduced medium is better than conventional medium. Cytotherapy 12: 587-592.
24. Mow VC, Ateshian GA, Spilker RL. 1993; Biomechanics of diarthrodial joints: a review of twenty years of progress. J Biomech Eng 115: 460-467.
25. Okamoto T, Aoyama T, Nakayama T et al. 2002; Clonal heterogeneity in differentiation potential of immortalized human mesenchymal stem cells. Biochem Biophys Res Commun 295: 354-361.
26. Pittenger MF, Mackay AM, Beck SC et al. 1999; Multilineage potential of adult human mesenchymal stem cells. Science 284: 143-147.
27. Quarto R, Mastrogiacomo M, Cancedda R et al. 2001; Repair of large bone defects with the use of autologous bone marrow stromal cells. N Engl J Med 344: 385-386.
28. Rago R, Mitchen J, Wilding G. 1990; DNA fluorometric assay in 96-well tissue culture plates using Hoechst 33258 after cell lysis by freezing in distilled water. Anal Biochem 191: 31-34.
29. Siffert RS. 1951; The role of alkaline phosphatase in osteogenesis. J Exp Med 93: 415-426.
30. Sotiropoulou PA, Perez SA, Salagianni M et al. 2006; Cell culture medium composition and translational adult bone marrow-derived stem cell research. Stem Cells 24: 1409-1410.
31. Sottile V, Halleux C, Bassilana F et al. 2002; Stem cell characteristics of human trabecular bone-derived cells. Bone 30: 699-704.
32. Sottile V, Thomson A, McWhir J. 2003; In vitro osteogenic differentiation of human ES cells. Cloning Stem Cells 5: 149-155.
33. Swieszkowski W, Tuan BH, Kurzydlowski KJ et al. 2007; Repair and regeneration of osteochondral defects in the articular joints. Biomol Eng 24: 489-495.
34. Tampieri A, Sandri M, Landi E et al. 2008; Design of graded biomimetic osteochondral composite scaffolds. Biomaterials 29: 3539-3546.
35. Tataria M, Quarto N, Longaker MT et al. 2006; Absence of the p53 tumor suppressor gene promotes osteogenesis in mesenchymal stem cells. J Pediatr Surg 41: 624-632.
36. Titorencu I, Jinga VV, Constantinescu E et al. 2007; Proliferation, differentiation and characterization of osteoblasts from human BM mesenchymal cells. Cytotherapy 9: 682-696.
37. Vinatier C, Mrugala D, Jorgensen C et al. 2009; Cartilage engineering: a crucial combination of cells, biomaterials and biofactors. Trends Biotechnol 27: 307-314.
38. Wang CY, Chen LL, Kuo PY et al. 2010; Apoptosis in chondrogenesis of human mesenchymal stem cells: effect of serum and medium supplements. Apoptosis 15: 439-449.
39. Young RG, Butler DL, Weber W et al. 1998; Use of mesenchymal stem cells in a collagen matrix for Achilles tendon repair. J Orthop Res 16: 406-413.