Enoyl acyl carrier protein reductase (FabI) catalyzed asymmetric reduction of the C=C double bond of α,β-unsaturated ketones: Preparation of (R)-2-alkyl-cyclopentanones

Chemical Communications

Volumn 50, Issue 68, 2014, Pages 9729-9732

  Liu, Ji ^a   Wu, Jinchuan ^b   Li, Zhi ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b INSTITUTE OF CHEMICAL AND ENGINEERING SCIENCES   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOPENTANE DERIVATIVE; CYCLOPENTANONE; ENOYL ACYL CARRIER PROTEIN REDUCTASE (NADH); KETONE; 2 ALKYLIDENECYCLOPENTANONE; ALPHA BETA UNSATURATED KETONE; CYCLOPENTANONE DERIVATIVE; GLUTAMATE DEHYDROGENASE; KETONE DERIVATIVE; UNCLASSIFIED DRUG;

ACINETOBACTER; ALKYLATION; CHEMICAL STRUCTURE; CHEMISTRY; ENZYMOLOGY; ESCHERICHIA COLI; GENETICS; METABOLISM; MOLECULAR CLONING; MOLECULAR DOCKING; OXIDATION REDUCTION REACTION; PROTEIN ENGINEERING; SYNTHESIS; ARTICLE; ASYMMETRIC CATALYSIS; BIOLOGICAL ACTIVITY; CHEMICAL ANALYSIS; CHEMICAL BOND; CHEMICAL REACTION; ENANTIOSELECTIVITY; ENZYME SPECIFICITY; GENOME ANALYSIS; NONHUMAN; ONE POT SYNTHESIS; OXIDATION; REDUCTION KINETICS;

ACINETOBACTER; ALKYLATION; CLONING, MOLECULAR; CYCLOPENTANES; ENOYL-(ACYL-CARRIER-PROTEIN) REDUCTASE (NADH); ESCHERICHIA COLI; KETONES; MODELS, MOLECULAR; MOLECULAR DOCKING SIMULATION; OXIDATION-REDUCTION; PROTEIN ENGINEERING;

EID: 84904963024     PISSN: 13597345     EISSN: 1364548X     Source Type: Journal    
DOI: 10.1039/c4cc04150j     Document Type: Article

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