Cytotoxicity and cytokine release in rat hepatocytes, C3A cells and macrophages exposed to gold nanoparticles - Effect of biological dispersion media or corona

Journal of Biomedical Nanotechnology

Volumn 10, Issue 11, 2014, Pages 3416-3429

  Brown, David M ^a   Johnston, Helinor ^a   Gubbins, Eva ^a   Stone, Vicki ^a  

^a HERIOT WATT UNIVERSITY   (United Kingdom)

Author keywords

C3A; Cytokine; Gold nanoparticles; Hepatocyte; Macrophage; Toxicity

Indexed keywords

BIOLOGICAL ORGANS; BODY FLUIDS; CELL CULTURE; CYTOTOXICITY; GOLD; GOLD ALLOYS; METAL NANOPARTICLES; PARTICLE SIZE; TOXICITY;

C3A; CYTOKINE RESPONSE; CYTOKINES; CYTOTOXIC EFFECTS; DIFFERENT EFFECTS; GOLD NANOPARTICLES; HEPATOCYTES; PRIMARY HEPATOCYTES;

MACROPHAGES;

BOVINE SERUM ALBUMIN; CYTOKINE; GOLD NANOPARTICLE; INTERLEUKIN 1BETA; INTERLEUKIN 6; LACTATE DEHYDROGENASE; MONOCYTE CHEMOTACTIC PROTEIN 1; TUMOR NECROSIS FACTOR ALPHA; GOLD; METAL NANOPARTICLE;

ANIMAL CELL; ARTICLE; CELL MIGRATION; CELL VIABILITY; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOTOXICITY; DISPERSION; HEPATOCELLULAR CARCINOMA CELL LINE; HUMAN; HUMAN CELL; LIGHT SCATTERING; LIVER CELL; MACROPHAGE; MALE; MOUSE; NONHUMAN; PARTICLE SIZE; RAT; ZETA POTENTIAL; ANIMAL; CELL CULTURE; CELL SURVIVAL; DRUG EFFECTS; IMMUNOLOGY; PATHOLOGY; SPRAGUE DAWLEY RAT; STRUCTURE ACTIVITY RELATION;

ANIMALS; CELL SURVIVAL; CELLS, CULTURED; GOLD; HEPATOCYTES; MACROPHAGES; MALE; METAL NANOPARTICLES; PARTICLE SIZE; RATS; RATS, SPRAGUE-DAWLEY; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84904894130     PISSN: 15507033     EISSN: 15507041     Source Type: Journal    
DOI: 10.1166/jbn.2014.1871     Document Type: Article

References (35)

1. J. M. Balbus, A. D. Maynard, V. L. Colvin, V. Castranova, G. P. Daston, R. A. Denison, K. L. Dreher, P. L. Goering, A. M. Goldberg, K. M. Kulinowski, N. A. Monteiro-Riviere, G. Oberdorster, G. S. Omenn, K. E. Pinkerton, K. S. Ramos, K. M. Rest, J. B. Sass, E. K. Silbergeld, and B. A. Wong, Meeting report: Hazard assessment for NPs - Report from an interdisciplinary workshop. Env. Hlth Perspect 115, 1654 (2007).
2. X. Gao, Y. Cui, R. M. Levenson, L. W. K. Chung, and S. Nie, In vivo cancer targeting and imaging with semiconductor quantum dots. Nat. Biotechnol. 22, 969 (2004).
3. G. Oberdorster, Z. Sharp, V. Atudorei, A. Elder, R. Gelein, A. Lunts, W. Kreyling, and C. Cox, Extrapulmonary translocation of ultrafine carbon particles following whole-body inhalation exposure of rats. J. Toxicol Environ. Health 65, 1531 (2002).
4. P. U. Jani, G. W. Halbert, J. Langridge, and A. T. Florence, Nanoparticle uptake by the rat gastrointestinal mucosa: quantitation and particle size dependency. J. Pharm. Pharmacol. 42, 821 (1990).
5. C. Schleh, M. Semmler-Behnke, J. Lipka, A. Wenk, S. Hirn, M. Schäffler, G. Schmid, U. Simon, and W. G. Kreyling, Size and surface charge of gold nanoparticles determine absorption across intestinal barriers and accumulation in secondary target organs after oral administration. Nanotoxicology 6, 36 (2012).
6. J. Lipka, M. Semmler-Behnke, R. A. Sperling, A. Wenk, S. Takenaka, C. Schleh, T. Kissel, W. J. Parak, and W. G. Kreyling. Biodistribution of PEG-modified gold nanoparticles following intratracheal instillation and intravenous injection. Biomaterials 31, 6574e (2010).
7. G. Oberdorster, A. Maynard, K. Donaldson, V. Castranova, J. Fitzpatrick, K. Ausman, J. Carter, B. Karn, W. Kreyling, D. Lai, S. Olin, N. Monteiro-Riviere, D. Warheit, and H. Yang, Principles for characterizing the potential human health effects from exposure to nanomaterials: elements of a screening strategy. Part Fibre Toxicol. 2, 8 (2005).
8. K. Ogawara, M. Yoshida, K. Higaki, T. Kimura, K. Shiraishi, M. Nishikawa, Y. Takakura, and M. Hashida, Hepatic uptake of polystyrene microspheres in rats: Effect of particle size on intrahepatic distribution. J Control Release 59, 15 (1999).
9. M. Semmler-Behnke, W. G. Kreyling, and J. Lipka, Biodistribution of 1.4 and 18nm gold particles in rats. Small 4, 2108 (2008).
10. A. Nemmar, P. H. Hoet, B. Vanquickenborne, D. Dinsdale, M. Thomeer, M. F. Hoylaerts, H. Vanbilloen, L. Mortelmans, and A. Nemery, Passage of inhaled particles into the blood circulation in humans. Circulation 105, 411 (2002).
11. S. Takenaka, E. Karg, C. Roth, H. Schulz, A. Ziesenis, U. Heinzmann, P. Schramel, and J. Heyder, Pulmonary and systemic distribution of inhaled ultrafine silver particles in rats. Environment Hlth Perspect 109, 547 (2001).
12. A. Nemmar, H. Vanbilloen, M. F. Hoylaerts, P. H. Hoet, A. Verbruggen, and A. Nemery, Passage of intratracheally instilled ultrafine particles from the lung into the systemic circulation in hamster. Am. J. Respir Critl. Care Med. 164, 1665 (2001).
13. M. Semmler, J. Seitz, F. Erbe, P. Mayer, J. Heyder, G. Oberdorster, and W. G. Kreyling, Long-term clearance kinetics of inhaled ultrafine insoluble iridium particles from the rat lung, including transient translocation into secondary organs. Inhal. Toxicol. 16, 453 (2004).
14. D. M. Brown, V. Stone, P. Findlay, W. MacNee, and K. Donaldson, Increased inflammation and intracellular calcium caused by ultrafine carbon black is independent of transition metals or other soluble components. Occup. Environ. Med. 57, 685 (2000).
15. D. M. Brown, C. Dickson, P. Duncan, F. Al-Attili, and V. Stone, Interaction between NPs and cytokine proteins: Impact on protein and particle functionality. Nanotechnology 21, 215104 (2010).
16. I. Lynch and K. A. Dawson, Protein-nanoparticle interactions. Nanotoday 3, 40 (2008).
17. M. P. Monopoli, D. Walczyk, A. Campbell, G. Elia, I. Lynch, F. Baldelli Bombelli, and K. A. Dawson, Physical-chemical aspects of protein corona: Relevance to in vitro and in vivo biological impacts of nanoparticles. J. Am. Chem. Soc. 133, 2525 (2011).
18. W. S. Cho, S. Kim, B. S. Han, W. C. Son, and J. Jeong, Comparison of gene expression profiles in mice liver following intravenous injection of 4 and 100 nm-sized PEG-coated gold nanoparticles. Toxicol. Lett. 191, 96 (2009).
19. V. Sharma, D. Anderson, and A. Dhawan, Zinc oxide nanoparticles induce oxidative stress and genotoxicity in human liver cells (HepG2). J. Biomed. Nanotechnol. 7, 98 (2011).
20. H. Ishii, S. Hayashi, J. C. Hogg, T. Fujii, Y. Goto, N. Sakamoto, H. Mukae, R. Vincent, and S. F. van Eeden, Alveolar macrophage-epithelial cell interaction following exposure to atmospheric particles induces the release of mediators involved in monocyte mobilization and recruitment. Respiratory Research 6, 87 (2005).
21. E. Sadauskas, H. Wallin, M. Stoltenberg, U. Vogel, P. Doering, A. Larsen, and G. Danscher, Kupffer cells are central in the removal of nanoparticles from the organism. Part Fibre Toxicol. 19, 4 (2007).
22. T. Morais, M. E. Soares, J. A. Duarte, L. Soares, S. Maia, P. Gomes, E. Pereira, S. Fraga, H. Carmo, and L. B. Mde, Effect of surface coating on the biodistribution profile of gold nanoparticles in the rat. Eur. J. Pharm. Biopharm. 80, 185 (2012).
23. R. P. Baughman, D. J. Mangels, S. Strohofer, and B. C. Corser, Enhancement of macrophage and monocyte cytotoxicity by the surface active material of lung lining fluid. Journal of Laboratory and Clinical Medicine 109, 692 (1987).
24. A. Gautam, O. C. Ng, and J. L. Boyer, Isolated rat hepatocyte couplets in short-term culture: Structural characteristics and plasma membrane reorganization. Hepatology 7, 216 (1987).
25. A. Kermanizadeh, G. Pojana, B. K. Gaiser, R. Birkedal, O. D. Bilanic, H. Wallin, K. A. Jensen, B. Sellergren, G. R. Hutchison, A. Marcomini, and V. Stone, In vitro assessment of engineered nanomaterials using a hepatocyte cell line: cytotoxicity, pro-inflammatory cytokines and functional markers. Nanotoxicology 7, 301 (2013).
26. M. J. Clift, M. S. P. Boyles, D. M. Brown, and V. Stone, An investigation into the potential for different surface-coated quantum dots to cause oxidative stress and affect macrophage cell signalling in vitro. Nanotoxicology 4, 139 (2010).
27. M. J. Clift, B. Rothen-Rutishauser, D. M. Brown, R. Duffin, K. Donaldson, L. Proudfoot, K. Guy, and V. Stone, The impact of different nanoparticle surface chemistry and size on uptake and toxicity in a murine macrophage cell line. Toxicol. Appl. Pharmacol. 232, 418 (2008).
28. L. Foucaud, M. R. Wilson, D. M. Brown, and V. Stone, Measurement of reactive species production by nanoparticles prepared in biologically relevant media. Toxicol Lett. 1, 1 (2007).
29. J. Ferin, G. Oberdoster, D. P. Penney, S. C. Soderholm, R. Gelein, and H. C. Piper, Increased pulmonary toxicity of ultrafine particles? I. Particle clearance, translocation, morphology. J. Aerosol. Sci. 21, 381 (1990).
30. G. Oberdoerster, J. Ferin, J. Finkelstein, P. Wade, and N. Corson, Increased pulmonary toxicity of ultrafine particles? II. Lung lavage studies. J. Aerosol. Sci. 21, 384 (1990).
31. V. Stone, J. Shaw, D. M. Brown, W. MacNee, S. P. Faux, and K. Donaldson, The role of oxidative stress in the prolonged inhibitory effect of ultrafine carbon black on epithelial cell function. Toxicol. In Vitro 12, 649 (1998).
32. V. Stone, M. Tuinman, J. E. Vamvakopoulos, J. Shaw, D. Brown, S. Petterson, S. P. Faux, P. Borm, W. MacNee, F. Michaelangeli, and K. Donaldson, Increased calcium influx in a monocytic cell line on exposure to ultrafine carbon black. Eur. Respir J. 15, 297 (2000).
33. D. M. Brown, M. R. Wilson, W. MacNee, V. Stone, and K. Donaldson, Size-dependent proinflammatory effects of ultrafine polystyrene particles: A role for surface area and oxidative stress in the enhanced activity of ultrafines. Toxicol. Appl. Pharmacol. 175, 191 (2001).
34. A. Kermanizadeh, B. K. Gaiser, M. B. Ward, and V. Stone, Primary human hepatocytes versus hepatic cell line: assessing their suitability for in vitro nanotoxicology. Nanotoxicology 7, 1255 (2012).
35. L. Treuel, M. Malissek, J. S. Gebauer, and R. Zellner, The influence of surface composition of NPs on their interactions with serum albumin. Eur. J. Chem. Phys. Chem. 11, 3093 (2010).